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ClinicalTrials.gov public records Last synced Oct 6, 2026, 11:41 PM EDT

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Showing 25–48 of 130 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Spinal cord transcutaneous stimulation Clear all
Recruiting Not applicable Interventional

Neuromodulation to Enhance Motor Function in HSP

NCT07417943
View directory record Official record
Conditions
Hereditary Spastic Paraplegia
Interventions
transcutaneous spinal cord stimulation
Device
Lead sponsor
Rahul Sachdeva
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Oct 6, 2026, 11:41 PM EDT
Terminated Not applicable Interventional Results available

Pairing Intermittent Hypoxia and Transcutaneous Electrical Spinal Cord Stimulation to Promote Arm Use After Cervical SCI

NCT04854057
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
AIH - Intermittent Hypoxia - hypoxia air mixture, SHAM - Intermittent Room Air - room air mixture, TESS - Transcutaneous Electrical Spinal Cord Stimulation + Functional Task Practice
Other · Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 10, 2024 · Synced Oct 6, 2026, 11:41 PM EDT
Active, not recruiting Not applicable Interventional

Electrical Neuromodulation for Modifying Spinal Network Involved in Spasticity

NCT07792616
View directory record Official record
Conditions
Spinal Cord Injuries (Complete and Incomplete), Spinal Cord Injury, Spinal Cord Injury Cervical, Spinal Cord Injury Thoracic, Spinal Cord Injuries, Spasticity, Spasm, Muscle Spasticity, Muscle Hypertonia, Muscle Spasm
Interventions
Transcutaneous spinal stimulation at 30 Hz, Transcutaneous spinal stimulation at 75 Hz, Tizanidine, Baclofen, Placebo
Other · Drug
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 6, 2026, 11:41 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Testing Non-Invasive Spinal Stimulation Devices

NCT07217314
View directory record Official record
Conditions
Healthy Participants
Interventions
Spinal Stimulation
Device
Lead sponsor
Gail Forrest
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Oct 6, 2026, 11:41 PM EDT
Active, not recruiting Early Phase 1 Interventional

Transformation of Paralysis to Stepping

NCT04105114
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Buspirone, Non-invasive Spinal Cord Stimulation, Overground stepping, Gravity Neutral Device, Body Weight Supported Treadmill Training, Rolling Walker
Drug · Device
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 13, 2026 · Synced Oct 6, 2026, 11:41 PM EDT
Not listed Not applicable Interventional

Using NI-ES to Treat Spinal Cord Injury (SCI)

NCT04097015
View directory record Official record
Conditions
Spinal Cord Injuries, Pain, Neuropathic
Interventions
Alpha-Stim M
Device
Lead sponsor
SCI Research Advancement
Other
Eligibility
Not listed
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Buellton, California
Source: ClinicalTrials.gov public record
Updated Oct 8, 2019 · Synced Oct 6, 2026, 11:41 PM EDT
Active, not recruiting Not applicable Interventional

Brain-Controlled Spinal Stimulation Walking Therapy After Incomplete Spinal Cord Injury (SCI)

NCT06406855
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Brain-Computer Interface-Triggered Transcutaneous Spinal Cord Stimulation (BCI-tSCS) System
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 70 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 6, 2026, 11:41 PM EDT
Completed Not applicable Interventional

Metabolic Health in Individuals With Spinal Cord Injury (SCI)

NCT03204240
View directory record Official record
Conditions
Spinal Cord Injuries, Skeletal Muscle Atrophy, Metabolic Disease
Interventions
Neuromuscular electrical stimulation
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 27, 2023 · Synced Oct 6, 2026, 11:41 PM EDT
Not listed Not applicable Interventional

Trancutaneous Abdominal Stimulation on Bowel Function.

NCT04627168
View directory record Official record
Conditions
Spinal Cord Injuries, Constipation
Interventions
Non-invasive, surface electrical stimulation device, DS5 Digitimer
Device
Lead sponsor
Amol Soin, M.D., MBA
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 13, 2022 · Synced Oct 6, 2026, 11:41 PM EDT
Recruiting Not applicable Interventional

Safety of Transcutaneous Electrical Stimulation Potentiating Recovery in Acute Spinal Cord Injury Syndromes

NCT07090473
View directory record Official record
Conditions
Acute Spinal Cord Injury (SCI), Acute Spinal Cord Injury of Traumatic Origin (tSCI)
Interventions
transcutaneous spinal cord stimulation, sham transcutaneous spinal cord stimulation
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Oct 6, 2026, 11:41 PM EDT
Suspended Not applicable Interventional

Non-Invasive Electrical and Magnetic Neuromodulation in Persons With Chronic Spinal

NCT05994846
View directory record Official record
Conditions
Spinal Cord Injuries, Spinal Cord Diseases
Interventions
RISES-T System
Device
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 9, 2025 · Synced Oct 6, 2026, 11:41 PM EDT
Recruiting Not applicable Interventional

Evaluating Safety and Feasibility of Transcutaneous Spinal Cord Stimulation Following Traumatic and Non-Traumatic Spinal Cord Injury: A Pilot Study

NCT06520020
View directory record Official record
Conditions
Spinal Cord Stimulation, Electric Stimulation Therapy, Traumatic Spinal Cord Injury, Cervical Myelopathy
Interventions
Transcutaneous Spinal Cord Stimulation (Tc-SCS)
Device
Lead sponsor
Francis Farhadi
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 6, 2026, 11:41 PM EDT
Completed Not applicable Interventional Results available

Spinal Stimulation and Mobility Devices

NCT05520359
View directory record Official record
Conditions
Cerebral Palsy, Stroke, Premature Birth, Hypoxic-Ischemic Encephalopathy, Periventricular Leukomalacia
Interventions
Mobility Device, Spinal Stimulation
Device
Lead sponsor
University of Washington
Other
Eligibility
4 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Oct 6, 2026, 11:41 PM EDT
Enrolling by invitation Not applicable Interventional

Neuromodulation of Spinal Locomotor Circuitry to Elicit Stepping After Pediatric Spinal Cord Injury

NCT04077346
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Biostim-5 transcutaneous spinal stimulator, Transcutaneous Spinal Stimulator + Activity Based Locomotor Training
Device · Other
Lead sponsor
University of Louisville
Other
Eligibility
4 Years to 12 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 6, 2026, 11:41 PM EDT
Active, not recruiting Not applicable Interventional

Autonomic Effects of Spinal Cord Stimulation in Spinal Cord Injury

NCT05960448
View directory record Official record
Conditions
Orthostatic Hypotension
Interventions
Transcutaneous Spinal Cord Stimulation (TSCS), Sham Transcutaneous Spinal Cord Stimulation
Other
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 6, 2026, 11:41 PM EDT
Recruiting Not applicable Interventional

Influence of Spinal Stimulation Frequency on Spasticity, Motor Control, and Pain After Spinal Cord Injury

NCT06214208
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Transcutaneous Spinal Stimulation
Other
Lead sponsor
Shepherd Center, Atlanta GA
Other
Eligibility
16 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Oct 6, 2026, 11:41 PM EDT
Completed Not applicable Interventional

Physiological Investigations of Movement Disorders

NCT01019343
View directory record Official record
Conditions
Parkinson's Disease, Tourette's Syndrome, Tic Disorders, Dystonia, Movement Disorders
Interventions
Transcranial Direct Current Stimulation (tDCS), Eye-tracking Device, Pulsed vibrator, Gait Trainer Treadmill (GTT), Standard psychiatric scales SCID-I, YBOCS and SCI-OBS-lifetime and cognitive scales MMSE and MOCA, iMobility, QMAT, Treadmill Test, Arm Intellistretch Device, Transcranial Sonography (TCS), Behavioral tasks, TMS single/paired pulse, MEG, EEG, MRI techniques, Peripheral Nerve Stimulation, EMG, Trancutaneous spinal direct current stimulation (tsDCS)
Procedure · Device · Other + 1 more
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
1,273 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Oct 6, 2026, 11:41 PM EDT
Completed Not applicable Interventional Results available

Noninvasive Spinal Stimulation in Stroke

NCT03714282
View directory record Official record
Conditions
Stroke
Interventions
Noninvasive spinal stimulation with gait training, Conventional gait training
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Oct 6, 2026, 11:41 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Transcutaneous Spinal Cord Stimulation in Healthy Adults

NCT06116838
View directory record Official record
Conditions
Healthy Adults
Interventions
Spinal motor evoked responses (sMERs), Continuous stimulation tolerance
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Oct 6, 2026, 11:41 PM EDT
Completed Not applicable Interventional Results available

Transspinal Stimulation Plus Locomotor Training for SCI

NCT04807764
View directory record Official record
Conditions
Spinal Cord Injuries, Paraplegia, Spinal, Tetraplegia/Tetraparesis, Paraplegia, Spastic
Interventions
Standing transspinal stimulation followed by robotic gait training, Lying transspinal stimulation followed by robotic gait training, Standing sham transspinal stimulation followed by robotic gait training
Combination Product · Other
Lead sponsor
City University of New York
Other
Eligibility
18 Years to 70 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
2
States / cities
Staten Island, New York • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 6, 2026, 11:41 PM EDT
Not yet recruiting Not applicable Interventional

Exoskeletal-assisted Walking Combined With Transcutaneous Spinal Cord Stimulation: Effect on Imaging and Serum Biomarkers of Skeletal Muscle Mass and Bone Strength.

NCT07418398
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Exoskeleton-Assisted Walking (EAW), Sham Transcutaneous Spinal Cord Stimulation (tSCS), Active Transcutaneous Spinal Cord Stimulation (tSCS)
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 60 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
2
States / cities
West Orange, New Jersey • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 6, 2026, 11:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Spinal Cord Stimulation for Restless Legs Syndrome

NCT03539081
View directory record Official record
Conditions
Restless Legs Syndrome, Neuropathic Pain
Interventions
Dual-energy X-ray absorptiometry Scan, Laboratory Measurements, Blood Flow Measurement, Continuous Blood Pressure, Partial pressure of oxygen, Microneurography, Anthropometric Measurements, John Hopkins Restless Legs Severity Scale, Continuous Blood Pressure Diary
Diagnostic Test · Other · Behavioral
Lead sponsor
Marshall Holland
Other
Eligibility
18 Years to 85 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 21, 2023 · Synced Oct 6, 2026, 11:41 PM EDT
Completed Not applicable Interventional Results available

Home Neuromodulation of the Neurogenic Bladder in Chronic Spinal Cord Injury With Transcutaneous Tibial Nerve Stimulation

NCT03458871
View directory record Official record
Conditions
Chronic Spinal Cord Injury, Neurogenic Bowel
Interventions
4-week TTNS home-based protocol
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 29, 2021 · Synced Oct 6, 2026, 11:41 PM EDT
Completed Not applicable Interventional

Restoring Arm and Hand Function With Non-invasive Spinal Stimulation

NCT01906424
View directory record Official record
Conditions
Paralysis, Spinal Cord Injury
Interventions
Transcutaneous Electrical Spinal Cord Stimulation
Device
Lead sponsor
NeuroEnabling Technologies, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
2
States / cities
Los Angeles, California • San Juan Capistrano, California
Source: ClinicalTrials.gov public record
Updated Jan 24, 2017 · Synced Oct 6, 2026, 11:41 PM EDT