Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced Sep 10, 2026, 9:20 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Intervention: Spinal manipulation Clear all
Terminated Not applicable Interventional Accepts healthy volunteers

Validation of CPR for Manipulation for Neck Pain

NCT02287337
View directory record Official record
Conditions
Cervicalgia
Interventions
Manipulation, Exercise
Procedure
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years to 70 Years
Enrollment
86 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Oct 21, 2019 · Synced Sep 10, 2026, 9:20 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Activator and Type II Diabetics

NCT01782092
View directory record Official record
Conditions
Type II Diabetes
Interventions
Chiropractic Adjustment
Other
Lead sponsor
Life University
Other
Eligibility
30 Years to 60 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Marietta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 19, 2016 · Synced Sep 10, 2026, 9:20 PM EDT
Recruiting Not applicable Interventional

Chiropractic Care for Episodic Migraine

NCT06229834
View directory record Official record
Conditions
Episodic Migraine
Interventions
Chiropractic Care, Headache Health Education
Procedure · Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Sep 10, 2026, 9:20 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Chiropractic Distraction Spinal Manipulation- Lumbar Stenosis Study

NCT03863769
View directory record Official record
Conditions
Spinal Stenosis Lumbar
Interventions
Lumbar Spinal Stenosis
Other
Lead sponsor
Parker University
Other
Eligibility
48 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 13, 2022 · Synced Sep 10, 2026, 9:20 PM EDT
Completed Not applicable Interventional

The Effect of Lumbopelvic Non-Thrust Spinal Manipulation on Individuals With Low Back Pain

NCT04646018
View directory record Official record
Conditions
Low Back Pain
Interventions
Lumbar Spine Manipulation, Sham Manipulation
Other
Lead sponsor
Alvernia University
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Reading, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 26, 2020 · Synced Sep 10, 2026, 9:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Changes in Functional Movement Scores Associated With Multimodal Chiropractic Care: a Pilot Feasibility Study

NCT05690568
View directory record Official record
Conditions
Chiropractic
Interventions
multimodal chiropractic care
Other
Lead sponsor
Cleveland University Kansas City
Other
Eligibility
21 Years to 35 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Jan 18, 2023 · Synced Sep 10, 2026, 9:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Non-Specific Effects of Manual Therapy

NCT03017534
View directory record Official record
Conditions
Musculoskeletal Manipulations, Placebo Effect
Interventions
Spinal Manual Therapy
Procedure
Lead sponsor
Shenandoah University
Other
Eligibility
18 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Winchester, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 8, 2017 · Synced Sep 10, 2026, 9:20 PM EDT
Completed Phase 1Phase 2 Interventional

Duration of Spinal Manipulation Effects as Influenced by Orthotics

NCT01704807
View directory record Official record
Conditions
Low Back Pain
Interventions
foot orthotics, Sham foot orthotic
Device
Lead sponsor
Logan College of Chiropractic
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Chesterfield, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 10, 2012 · Synced Sep 10, 2026, 9:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Looking Beyond the Immediate Effects of Lumbar Spinal Manipulation Using Pain Pressure Threshold in Asymptomatic Individuals

NCT06156605
View directory record Official record
Conditions
Lumbar Spine Injury, Pain
Interventions
Sidelying lumbar manipulation
Procedure
Lead sponsor
University of Mary
Other
Eligibility
18 Years to 50 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Bismarck, North Dakota
Source: ClinicalTrials.gov public record
Updated Dec 4, 2023 · Synced Sep 10, 2026, 9:20 PM EDT
Completed Not applicable Interventional

Effects of Cervical Manual Therapy on Cervicogenic Headache

NCT03385889
View directory record Official record
Conditions
Unilateral Headache, Musculoskeletal Neck Pain
Interventions
Cervical Spine Mobilization, Cervical Spine Manipulation
Procedure
Lead sponsor
Shenandoah University
Other
Eligibility
18 Years to 70 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Winchester, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 3, 2019 · Synced Sep 10, 2026, 9:20 PM EDT
Completed Not applicable Interventional Results available

Validation of the STarT Back Screening Tool in the Military

NCT03127826
View directory record Official record
Conditions
Low Back Pain, Lumbago, Radiculopathy, Intervertebral Disc Disorder
Interventions
Risk Stratified Care, Usual Care
Procedure
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 50 Years
Enrollment
290 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Sep 10, 2026, 9:20 PM EDT
Completed Not applicable Interventional

Cervical and Upper Thoracic Mobilization and Manipulation for Mechanical Neck Pain

NCT02036905
View directory record Official record
Conditions
Neck Pain
Interventions
Cervical and thoracic mobilization, cervical and thoracic manipulation
Other
Lead sponsor
Youngstown State University
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
2
States / cities
Solon, Ohio • Havertown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 25, 2016 · Synced Sep 10, 2026, 9:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Influence of Spinal Manipulative Therapy Upon Stroop Task Performance

NCT00335426
View directory record Official record
Conditions
Motor Response Time
Interventions
Spinal manipulative therapy
Procedure
Lead sponsor
Logan College of Chiropractic
Other
Eligibility
18 Years to 35 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2006
U.S. locations
1
States / cities
Chesterfield, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 31, 2009 · Synced Sep 10, 2026, 9:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Predicting Patients' Response to Spinal Manipulation

NCT00285649
View directory record Official record
Conditions
Low Back Pain
Interventions
HVLA-SM, LVVA-SM, Usual Medical Care
Other
Lead sponsor
Palmer College of Chiropractic
Other
Eligibility
21 Years to 55 Years
Enrollment
192 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Davenport, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 15, 2017 · Synced Sep 10, 2026, 9:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cervical Spine Manipulation Affects on Balance and Proprioception

NCT01745705
View directory record Official record
Conditions
Neck Pain, Headache
Interventions
Cervical Spine Manipulation, Manual Contact
Other
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years to 60 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Jun 18, 2013 · Synced Sep 10, 2026, 9:20 PM EDT
Completed Not applicable Interventional

Using fMRI to Determine if Cerebral Hemodynamic Responses to Pain Change Following Thoracic Spine Manipulation in Individuals With Mechanical Neck Pain

NCT01862705
View directory record Official record
Conditions
Neck Pain
Interventions
Thoracic spine manipulation
Other
Lead sponsor
OSF Healthcare System
Other
Eligibility
18 Years to 60 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Peoria, Illinois
Source: ClinicalTrials.gov public record
Updated May 12, 2015 · Synced Sep 10, 2026, 9:20 PM EDT
Not listed No phase listed Observational

Applying Pain Adaptability to Manual Therapy Practice

NCT05209659
View directory record Official record
Conditions
Musculoskeletal Manipulations, Low Back Pain
Interventions
Pragmatic Mobilization
Other
Lead sponsor
Youngstown State University
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
3
States / cities
Haslett, Michigan • Old Bridge, New Jersey • Canfield, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 28, 2022 · Synced Sep 10, 2026, 9:20 PM EDT
Completed Phase 2 Interventional

Elderly Back Pain: Comparing Chiropractic to Medical Care

NCT00602901
View directory record Official record
Conditions
Subacute Low Back Pain, Chronic Low Back Pain
Interventions
HVLA-SM, LVVA-SM, Usual medical care
Other · Drug
Lead sponsor
Palmer College of Chiropractic
Other
Eligibility
55 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
2
States / cities
Davenport, Iowa • Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Apr 5, 2017 · Synced Sep 10, 2026, 9:20 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

MIST3: Active Patient Safety Reporting

NCT04161677
View directory record Official record
Conditions
Safety Issues
Interventions
Not listed
Lead sponsor
Parker University
Other
Eligibility
18 Years to 65 Years
Enrollment
161 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 15, 2021 · Synced Sep 10, 2026, 9:20 PM EDT
Terminated Phase 1 Interventional

Study of Chiropractic and Neuromuscular Reeducation as a Treatment for Autism Symptoms

NCT01996800
View directory record Official record
Conditions
Autism
Interventions
Spinal Manipulative Therapy (SMT), SMT and Neuromuscular Reeducation
Procedure
Lead sponsor
Southern California University of Health Sciences
Other
Eligibility
5 Years to 15 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Whittier, California
Source: ClinicalTrials.gov public record
Updated Oct 3, 2016 · Synced Sep 10, 2026, 9:20 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Exploring How Osteopathic Manipulative Treatment May Affect Spinal Fluid Flow: An MRI Study

NCT07629765
View directory record Official record
Conditions
Osteopathic Manipulative Treatment (OMT) Effects on Cerebrospinal Fluid (CSF) Dynamics
Interventions
Osteopathic Manipulative Treatment (OMT)
Other
Lead sponsor
Edward Via Virginia College of Osteopathic Medicine
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Sep 10, 2026, 9:20 PM EDT
Completed Not applicable Interventional Results available

Comparative Effectiveness of Early Physical Therapy Versus Usual Care for Low Back Pain

NCT01556581
View directory record Official record
Conditions
Low Back Pain
Interventions
Usual Care (UC), Early Physical Therapy (PT)
Procedure
Lead sponsor
Madigan Army Medical Center
Federal
Eligibility
18 Years to 60 Years
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Jul 13, 2020 · Synced Sep 10, 2026, 9:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Assessing Student Learning of Spinal Mobilization With Real-time Objective Feedback

NCT05445622
View directory record Official record
Conditions
Healthy
Interventions
learning spinal mobilization with a force sensor
Other
Lead sponsor
Youngstown State University
Other
Eligibility
20 Years to 60 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Youngstown, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 5, 2022 · Synced Sep 10, 2026, 9:20 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Pregnancy-Related Low Back Pain and Complementary and Alternative Medicine (CAM) Treatment

NCT00937365
View directory record Official record
Conditions
Low Back Pain
Interventions
Exercise, Spinal Manipulation, Neuroemotional Technique (NET)
Behavioral · Procedure
Lead sponsor
Oregon Health and Science University
Other
Eligibility
20 Years to 49 Years · Female only
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Dec 17, 2019 · Synced Sep 10, 2026, 9:20 PM EDT