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ClinicalTrials.gov public records Last synced Oct 17, 2026, 11:08 PM EDT

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Showing 145–168 of 222 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Spinal-Block Clear all
Recruiting Not applicable Interventional

Evaluating a Strategy to Improve Pre-Anesthesia Care Discussions (My Anesthesia Choice-Hip Fracture)

NCT06438640
View directory record Official record
Conditions
Hip Fractures, Femoral Neck Fractures, Intertrochanteric Fractures, Subtrochanteric Fractures
Interventions
My Anesthesia Choice-HF Model
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
50 Years and older
Enrollment
1,881 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
6
States / cities
Gainesville, Florida • Detroit, Michigan • Lebanon, New Hampshire + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Oct 17, 2026, 11:08 PM EDT
Terminated No phase listed Observational

Delirium, Intraoperative Cerebral Perfusion and EEG Abnormalities After Total Hip Arthroplasty

NCT02818764
View directory record Official record
Conditions
Delirium, Hip Arthroplasty, Elderly
Interventions
Blood Draw, Cerebral Spinal Fluid collection, Electroencephalogram, Cerebral blood flow and oxygen extraction fraction
Procedure · Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
65 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 23, 2020 · Synced Oct 17, 2026, 11:08 PM EDT
Completed No phase listed Observational

Continuous Blockade of the Brachial Plexus

NCT02769429
View directory record Official record
Conditions
Arthroses, Degenerative Disorder, Osteoarthritis
Interventions
Ultrasound-guided CISB, nerve stimulator-guided CCPVB
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 25, 2019 · Synced Oct 17, 2026, 11:08 PM EDT
Completed Phase 2 Interventional Results available

Erector Spinae Plane Block for Uncomplicated Renal Colic

NCT05625802
View directory record Official record
Conditions
Renal Colic, Kidney Stone
Interventions
Erector Spinae Plane Block (ESPB), Ropivacaine
Procedure · Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Oct 17, 2026, 11:08 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Transvaginal Versus Fluoroscopy-guided Trans Gluteal Pudendal Nerve Block for Pudendal Neuralgia

NCT06644261
View directory record Official record
Conditions
Pudendal Neuralgia, Chronic Pelvic Pain Syndrome
Interventions
Bupivacaine injection
Drug
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 18, 2024 · Synced Oct 17, 2026, 11:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Music on Satisfaction, Anxiety, and Hemodynamics During Spinal Anesthesia for Cesarean Delivery

NCT02732964
View directory record Official record
Conditions
Anxiety, Hypotension
Interventions
Pandora Music, Mozart Music
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 30, 2017 · Synced Oct 17, 2026, 11:08 PM EDT
Not yet recruiting Phase 4 Interventional

ESP Blocks for Posterior Spinal Fusion

NCT07228039
View directory record Official record
Conditions
Postoperative Pain
Interventions
ESP Block with Bupivacaine, ESP Block with Bupivacaine + Liposomal Bupivacaine
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 75 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 17, 2026, 11:08 PM EDT
Completed Phase 2Phase 3 Interventional

Intravenous Ondansetron to Attenuate the Hypotensive, Bradycardic Response to Spinal Anesthesia in Healthy Parturients

NCT01414777
View directory record Official record
Conditions
Hypotension, Pregnancy
Interventions
ondansetron, placebo
Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 24, 2022 · Synced Oct 17, 2026, 11:08 PM EDT
Withdrawn Not applicable Interventional

Extra Sitting Time After Spinal Anesthesia for Cesarean Section and Fetal Well-being

NCT02893696
View directory record Official record
Conditions
Complications; Cesarean Section, Hypotension
Interventions
Various sitting time
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 31, 2019 · Synced Oct 17, 2026, 11:08 PM EDT
Recruiting Phase 3 Interventional

Opioid-Sparing Joint Replacement

NCT07348627
View directory record Official record
Conditions
Pain Management, Opioid Consumption
Interventions
Placebo, Oxycodone 5 mg, Multimodal Non-Opioid Analgesia
Drug · Other
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 17, 2026 · Synced Oct 17, 2026, 11:08 PM EDT
Terminated Phase 4 Interventional Results available

Evaluation of the Safety and Efficacy of EXPAREL When Administered Into the TAP in Subjects Undergoing Cesarean Section

NCT02353754
View directory record Official record
Conditions
Pain
Interventions
Intrathecal morphine injection, EXPAREL
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
18 Years and older · Female only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
5
States / cities
Port Saint Lucie, Florida • Minneapolis, Minnesota • New Brunswick, New Jersey + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 26, 2021 · Synced Oct 17, 2026, 11:08 PM EDT
Completed Not applicable Interventional Results available

Liposomal Bupivacaine Versus Standard Analgesia in Total Joint Arthroplasty (TJA)

NCT02197273
View directory record Official record
Conditions
Osteoarthritis, Knee, Osteoarthritis, Hip, Osteoarthritis, Shoulder
Interventions
Liposomal bupivacaine, Standard of care analgesia
Drug
Lead sponsor
OhioHealth
Other
Eligibility
18 Years and older
Enrollment
211 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 21, 2016 · Synced Oct 17, 2026, 11:08 PM EDT
Completed Phase 4 Interventional Results available

Spinal Anesthesia Induced Hypotension During Cesarean Section

NCT00846651
View directory record Official record
Conditions
Hypotension
Interventions
Colloid administration, Crystalloid administration, phenylephrine infusion
Other · Drug
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 16, 2017 · Synced Oct 17, 2026, 11:08 PM EDT
Enrolling by invitation Phase 3 Interventional Accepts healthy volunteers

GA + ESP vs. SA + ESP in Lumbar Decompression Surgeries

NCT05444751
View directory record Official record
Conditions
Lumbar Disc Herniation, Lumbar Disc Disease, Lumbar Radiculopathy
Interventions
General anesthetic, SA + ESP
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 80 Years
Enrollment
142 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 17, 2026, 11:08 PM EDT
Completed Not applicable Interventional

Dexmedetomidine After Cesarean for the Treatment of Nausea and Shivering

NCT03370562
View directory record Official record
Conditions
Shivering, Nausea and Vomiting, Postoperative
Interventions
Dexmedetomidine, Placebo
Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 1, 2021 · Synced Oct 17, 2026, 11:08 PM EDT
Terminated Phase 2 Interventional Results available

Chloroprocaine Spinal for Outpatient Knee Surgery

NCT03365752
View directory record Official record
Conditions
Knee Arthroscopy
Interventions
Chloroprocaine, Mepivacaine, General Anesthetics
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 80 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 20, 2022 · Synced Oct 17, 2026, 11:08 PM EDT
Completed Not applicable Interventional

FLO2 for Recovery After SCI

NCT03833674
View directory record Official record
Conditions
Spinal Cord Injury (SCI)
Interventions
Daily AIH Block, Sham dAIH Block, Respiratory Strength Training Block, AIH + Strength Training Block
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 70 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated May 29, 2024 · Synced Oct 17, 2026, 11:08 PM EDT
Recruiting Not applicable Interventional

Minimal Sedation During Knee Replacement Surgery

NCT07371390
View directory record Official record
Conditions
Total Knee Arthroplasty
Interventions
Active Noise Cancelling Headset System
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Oct 17, 2026, 11:08 PM EDT
Withdrawn Phase 3 Interventional

Intraoperative Transversus Abdominis Plane Block for Gynecologic Surgery (GYNTAP)

NCT02506855
View directory record Official record
Conditions
Postoperative Pain, Postoperative Nausea and Vomiting
Interventions
Ropivacaine, Placebo, Transversus Abdominis Plane Block
Drug · Other · Procedure
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated May 13, 2016 · Synced Oct 17, 2026, 11:08 PM EDT
Terminated Not applicable Interventional Results available

Determination of ED90 of Intrathecal Lidocaine for Adequate Anesthesia for Elective Cervical Cerclage Surgery

NCT02574832
View directory record Official record
Conditions
Pregnancy, Surgery, Pain
Interventions
Lidocaine Administration
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 20, 2018 · Synced Oct 17, 2026, 11:08 PM EDT
Completed Phase 2 Interventional Results available

Vaccine Responses in Tralokinumab-Treated Atopic Dermatitis - ECZTRA 5 (ECZema TRAlokinumab Trial No. 5)

NCT03562377
View directory record Official record
Conditions
Atopic Dermatitis
Interventions
Tralokinumab, Placebo, Tdap vaccine, Meningococcal vaccine
Drug · Biological
Lead sponsor
LEO Pharma
Industry
Eligibility
18 Years to 54 Years
Enrollment
215 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
39
States / cities
Fort Smith, Arkansas • Bakersfield, California • Beverly Hills, California + 33 more
Source: ClinicalTrials.gov public record
Updated Mar 11, 2025 · Synced Oct 17, 2026, 11:08 PM EDT
Completed Not applicable Interventional Results available

Spinal Morphine vs. Hydromorphone for Pain Control After Cesarean Delivery

NCT02789410
View directory record Official record
Conditions
Analgesia, Obstetrical, Obstetric Surgical Procedures
Interventions
Morphine, Hydromorphone
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 25, 2019 · Synced Oct 17, 2026, 11:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study to Find Optimal Dose of Local Spinal Anesthetic (Mepivacaine) Combined With Narcotic (Fentanyl) For Knee Surgery

NCT01701102
View directory record Official record
Conditions
Arthroscopic Knee Surgery
Interventions
Mepivacaine (24 mg) plus fentanyl, Mepivacaine (27 mg) plus fentanyl, Mepivacaine (30 mg) plus fentanyl, Mepivacaine
Procedure
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 60 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 5, 2016 · Synced Oct 17, 2026, 11:08 PM EDT
Completed Not applicable Interventional

A User-friendly, Non-invasive Neuro-orthosis That Restores Volitionally Controlled Grasp Functions for SCI Survivors With Tetraplegia

NCT06087445
View directory record Official record
Conditions
Cervical Spinal Cord Injury
Interventions
NeuroLife EMG-FES Sleeve System
Device
Lead sponsor
Ohio State University
Other
Eligibility
22 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Oct 17, 2026, 11:08 PM EDT