Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Oct 21, 2026, 11:07 PM EDT

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Showing 73–96 of 124 matching trials from the live ClinicalTrials.gov search.
Conditions
Plantar Fasciitis, Plantar Fasciopathy
Interventions
Ankle Dorsiflexion Dynasplint, Commercially Available Static Night splint
Device · Procedure
Lead sponsor
Dynasplint Systems, Inc.
Industry
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
1
States / cities
Lewisburg, Pennsylvania
Conditions
Carpometacarpal (CMC) Joint Arthritis
Interventions
Woodcasting Splint, Control (Standard treatment)
Other
Lead sponsor
Foundation for Orthopaedic Research and Education
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Obstructive Sleep Apnea Treatment in Serious Mental Illness

NCT05457127
Conditions
Schizoaffective Disorder, Schizophrenia, Bipolar Disorder, Obstructive Sleep Apnea of Adult
Interventions
Automatic Positive Airway Pressure (APAP)
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
40 Years to 70 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
La Jolla, California
Conditions
Arthritis, Osteoarthritis Hand, Scleroderma, Systemic, Scleroderma, Diffuse, Rheumatoid Arthritis
Interventions
Custom Fabricated Splint
Other
Lead sponsor
Giovanna Fichera
Other
Eligibility
18 Years to 100 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Troy, New York
Conditions
Carpal Tunnel Syndrome
Interventions
Theraworx Foam, Placebo Foam, Theraworx Foam and night splint, Placebo Foam and night time splint
Drug · Other
Lead sponsor
John Fowler
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers Results available

Nocturnal Mouth Guards, SOVA vs. Standard Acrylic Orthotic; Phase IV

NCT02340663
Conditions
Sleep Bruxism, Tooth Wear
Interventions
SOVA Bite Splint, Michigan Bite Splint
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 70 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Not yet recruiting Not applicable Interventional

Tools for Return of Facial Function

NCT07825844
Conditions
Facial Scarring, Facial Trauma, Burn, Orofacial Contracture, Facial Scar Contracture
Interventions
Intraoral Stretching Splints
Device
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
7 Years to 100 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Galveston, Texas
Terminated Not applicable Interventional Results available

Diabetes-Obstructive Sleep Apnea Treatment Trial

NCT01901055
Conditions
Type 2 Diabetes, Obstructive Sleep Apnea
Interventions
CPAP, Sham-CPAP, Diabetes Education
Device · Behavioral
Lead sponsor
Eileen R. Chasens
Other
Eligibility
18 Years and older
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
4
States / cities
Detroit, Michigan • Pittsburgh, Pennsylvania • Morgantown, West Virginia
Conditions
Hemiparesis, Cerebral Palsy
Interventions
Neurorehabilitation therapy with cast, Neurorehabilitation therapy with splint, Neurorehabilitation bimanual
Behavioral
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
6 Months to 24 Months
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
3
States / cities
Columbus, Ohio • Charlottesville, Virginia • Roanoke, Virginia
Conditions
Sleep Apnea, Obstructive, Diabetes Mellitus, Type 2
Interventions
Continuous Positive Airway Pressure (CPAP), Sham- Continuous Positive Airway Pressure (Sham-CPAP)
Device
Lead sponsor
Eileen R. Chasens
Other
Eligibility
40 Years to 65 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Thumb Osteoarthritis, First Dorsal Interosseous Strengthening
Interventions
Splint, Splint with strengthening exercises
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Temporomandibular Disorders
Interventions
Chiropractic w/Activator & Self Care, Dental Care & Self Care, Sham AMCT, Self-Care Only Group
Device · Other
Lead sponsor
Palmer College of Chiropractic
Other
Eligibility
21 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
3
States / cities
Coralville, Iowa • Davenport, Iowa • Iowa City, Iowa
Conditions
Tracheobronchomalacia
Interventions
Bioresorbable Tracheobronchial Splint
Device
Lead sponsor
University of Michigan
Other
Eligibility
1 Week to 3 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2034
U.S. locations
1
States / cities
Ann Arbor, Michigan
Completed Phase 3 Interventional Accepts healthy volunteers

Effectiveness of Splinting After Collagenase Injection

NCT04874870
Conditions
Dupuytren Contracture, Dupuytren's Disease
Interventions
Collagenase Clostridium Histolyticum 0.9 MG [Xiaflex], Xiaflex + Hand-Based Custom Orthosis
Drug · Combination Product
Lead sponsor
Foundation for Orthopaedic Research and Education
Other
Eligibility
18 Years to 90 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Tampa, Florida
Conditions
Carpal Tunnel Syndrome
Interventions
Early Carpal Tunnel Release for Mild or Moderate CTS, MR Nerve Imaging for CTS
Procedure · Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
1
States / cities
Seattle, Washington
Completed No phase listed Observational Results available

A Clinical Trial of Splinting for DeQuervain's Tenosynovitis

NCT00438191
Conditions
DeQuervain's Tenosynovitis
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Not listed Not applicable Interventional Accepts healthy volunteers

Treatment of Carpal Tunnel Syndrome With Dynamic Splinting

NCT00558116
Conditions
Carpal Tunnel Syndrome
Interventions
Dynamic splinting
Device
Lead sponsor
Advanced Centers for Orthopaedic Surgery and Sports Medicine
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Owings Mills, Maryland
Conditions
Nail Bed Injury, Nail Laceration, Nail Plate Disruption
Interventions
Nail Bed Repair, Nail bed dressing
Other
Lead sponsor
Stanford University
Other
Eligibility
2 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Palo Alto, California
Conditions
Obstructive Sleep Apnea
Interventions
Mandibular advancement device (MAD)
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Distal Radius Fracture
Interventions
Early Mobilization Protocol, Late Mobilization Protocol
Procedure
Lead sponsor
Robert Wood Johnson Barnabas Health
Other
Eligibility
18 Years to 75 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Somerset, New Jersey
Conditions
Ankle Fractures, Ankle Fracture - Lateral Malleolus, Ankle Fracture, Bimalleolar, Ankle Fracture, Trimalleolar, Ankle Fracture - Medial Malleolus, Maisonneuve's Fracture, Syndesmotic Injuries, Fibula Fracture
Interventions
Tourniquet
Procedure
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 89 Years
Enrollment
390 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Portland, Oregon
Conditions
Carpal Tunnel Syndrome
Interventions
Osteopathic manipulative treatment (OMT), Conservative treatment
Other
Lead sponsor
Kettering Health Network
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Dayton, Ohio
Conditions
Assessment of Vertical Dimension Change
Interventions
Occlusal Vertical Dimension Modification (+4mm), Occlusal Vertical Dimension Modification (-2 mm), Occlusal Vertical Dimension Modification (0 mm), Occlusal Vertical Dimension Modification (+2mm)
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
21 Years to 90 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Houston, Texas
Conditions
Carpal Tunnel Syndrome
Interventions
Group One, Control Group Two
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
Not listed
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Columbia, Missouri