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ClinicalTrials.gov public records Last synced Oct 20, 2026, 9:44 PM EDT

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Showing 1–24 of 33 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Split dose preparation Clear all
Withdrawn No phase listed Observational Accepts healthy volunteers

The Effect of Adding Lubiprostone to Standard Large-Volume PEG-ELS on The Quality of Inpatient Colonoscopy Preparation

NCT04361656
View directory record Official record
Conditions
Colonoscopy Preparation
Interventions
PEG-ELS current standard of care, PEG-ELS current standard of care plus Lubiprostone 24 microgram Oral Cap (x2)
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
3
States / cities
Novi, Michigan • Southfield, Michigan • Warren, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 19, 2025 · Synced Oct 20, 2026, 9:44 PM EDT
Completed Phase 2 Interventional

Safety, Efficacy, and Patient Preference of Split-Dose Crystalline Lactulose as a Preparation for Colonoscopy in Adults

NCT01650870
View directory record Official record
Conditions
Colonoscopy
Interventions
Crystalline Lactulose
Drug
Lead sponsor
Benaroya Research Institute
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 8, 2014 · Synced Oct 20, 2026, 9:44 PM EDT
Active, not recruiting Phase 2 Interventional

High vs. Standard Dose Influenza Vaccine in Adult SOT Recipients

NCT04613206
View directory record Official record
Conditions
Immunization; Infection, Transplantation Infection, Influenza, Solid Organ Transplant
Interventions
High Dose Quadrivalent Inactivated Influenza Vaccine, Standard Dose Quadrivalent Inactivated Influenza Vaccine
Biological
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
396 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 20, 2026, 9:44 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

A Trial Comparing Split-Dose Miralax With Amitiza Pretreatment Versus Dulcolax Pretreatment Versus Golytely for Bowel Cleansing Prior to Colonoscopy

NCT00953017
View directory record Official record
Conditions
Colonoscopy
Interventions
Miralax (PEG 3350), Amitiza (Lubiprostone), Dulcolax (Bisacodyl), Golytely (polyethylene glycol)
Drug
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years and older
Enrollment
425 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Nov 30, 2012 · Synced Oct 20, 2026, 9:44 PM EDT
Completed Phase 4 Interventional

Assessment of Safety, Quality, and Acceptance of a Bowel Preparation Using a Food Kit With Laxatives

NCT07605897
View directory record Official record
Conditions
Bowel Preparation, Efficacy, Tolerability, Safety, Colon Cancer Screening, Bowel Preparation for Colonoscopy
Interventions
Use of a standardized meal content (food-kit) the day prior to colonoscopy, Polyethylene glycol 3350 - electrolyte solution (GoLYTELY)
Other · Drug
Lead sponsor
Joseph Spataro
Federal
Eligibility
18 Years to 69 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Oct 20, 2026, 9:44 PM EDT
Active, not recruiting Not applicable Interventional

Impact of Chewing Gum on Bowel Preparation in Patients Undergoing Colonoscopy

NCT07320989
View directory record Official record
Conditions
Colon Cancer Screening
Interventions
Chewing Sugar-Free Gum During Bowel Preparation, Standard Bowel Prep (2L PEG-ELP), Standard Bowel Prep
Behavioral · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
45 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Towson, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 17, 2026 · Synced Oct 20, 2026, 9:44 PM EDT
Completed Phase 4 Interventional Results available

MoviPrep® Versus GoLYTELY® Bowel Preparation in Hospitalized Patients Undergoing Colonoscopy

NCT05054036
View directory record Official record
Conditions
Bowel Preparation Before Colonoscopy
Interventions
MoviPrep, Golytely
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
520 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
2
States / cities
Bridgeport, Connecticut • New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Oct 20, 2026, 9:44 PM EDT
Completed Not applicable Interventional

EGD-assisted Bowel Preparation for Colonoscopy

NCT01563744
View directory record Official record
Conditions
Esophagoscopy Techniques, Colonoscopy
Interventions
EGD-assisted administration of colonoscopy prep, Control Group received standard prep by oral administration
Procedure
Lead sponsor
Rockford Gastroenterology Associates
Other
Eligibility
Not listed
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
2
States / cities
Rockford, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 19, 2016 · Synced Oct 20, 2026, 9:44 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Morning-Only 4 L PEG vs Split Dose Prep for Afternoon Colonoscopies, Endoscopist-Blinded Prospective Study

NCT02643316
View directory record Official record
Conditions
Colonoscopy
Interventions
Same day 4 L preparation (Polyethylene Glycol), Split dose 4 L preparation (Polyethylene Glycol)
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Dec 4, 2019 · Synced Oct 20, 2026, 9:44 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Evaluation of a PillCam Colon Bowel Preparation Regimen in Crohn's Disease Patients

NCT01576120
View directory record Official record
Conditions
Crohn's Disease
Interventions
bowel prep regimen first boost 6 oz. and second boost 3 oz., bowel prep regimen first boost 3 oz. and second boost 6 oz.
Other
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
2
States / cities
Atlanta, Georgia • Beavercreek, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 8, 2019 · Synced Oct 20, 2026, 9:44 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study to Evaluate the Safety and Immunogenicity of a Single Dose of H1ssF-3928 mRNA-LNP in Healthy Adults

NCT05755620
View directory record Official record
Conditions
Influenza
Interventions
Influenza Virus Quadrivalent Inactivated Vaccine, Sodium Chloride, 0.9%, VRC-FLUNPF099-00-VP (H1ssF_3928)
Biological · Other
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years to 49 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 20, 2026, 9:44 PM EDT
Active, not recruiting Phase 2 Interventional

High vs. Standard Dose Influenza Vaccine in Lung Allograft Recipients

NCT05215327
View directory record Official record
Conditions
Immunization; Infection, Transplantation Infection, Influenza
Interventions
High Dose Quadrivalent Inactivated Influenza Vaccine, Standard Dose Quadrivalent Inactivated Influenza Vaccine
Biological
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
16 Years and older
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 20, 2026, 9:44 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Efficacy Study of Bowel Preparation Before Colonoscopy

NCT00621920
View directory record Official record
Conditions
Bowel Cleansing Prior to Colonoscopy
Interventions
FM-601
Drug
Lead sponsor
C.B. Fleet Company, Inc.
Industry
Eligibility
50 Years and older
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
2
States / cities
Anaheim, California • Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Feb 10, 2012 · Synced Oct 20, 2026, 9:44 PM EDT
Completed Not applicable Interventional

Comparison of Two Methods of Bowel Preparation for Colonoscopy in Hospitalized Patients

NCT01765491
View directory record Official record
Conditions
Bowel Preparation for Colonoscopy
Interventions
Split-dose polyethylene glycol, Morning-only polyethylene glycol
Other
Lead sponsor
Cook County Health
Government
Eligibility
18 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 18, 2023 · Synced Oct 20, 2026, 9:44 PM EDT
Terminated Not applicable Interventional

Effect of Use of Straw on Tolerability and Quality of Split Dose 4l-PEG Preparation

NCT02317731
View directory record Official record
Conditions
Colon Cancer
Interventions
Straw
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 18, 2016 · Synced Oct 20, 2026, 9:44 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

2 Regimens of Lactulose for Colonoscopy Preparation in Adults

NCT01887470
View directory record Official record
Conditions
Colonoscopy Preparation
Interventions
Full dose preparation, Split dose preparation
Drug
Lead sponsor
Cumberland Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Chattanooga, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 1, 2015 · Synced Oct 20, 2026, 9:44 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Safety and Efficacy Study of an Edible Colonoscopy Preparation

NCT03332485
View directory record Official record
Conditions
Colon Prep for Colonoscopy
Interventions
ECP Colon Prep Kit, MoviPrep®
Drug
Lead sponsor
Sebela Pharmaceuticals Development LLC
Industry
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
8
States / cities
Anaheim, California • Indianapolis, Indiana • Bastrop, Louisiana + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 19, 2018 · Synced Oct 20, 2026, 9:44 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Live Attenuated ETEC Vaccine ACE527 With and Without dmLT Adjuvant in Adults

NCT01739231
View directory record Official record
Conditions
Diarrhea
Interventions
ACE527, dmLT, CeraVacx placebo, H10407 challenge strain
Biological
Lead sponsor
PATH
Other
Eligibility
18 Years to 50 Years
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 12, 2019 · Synced Oct 20, 2026, 9:44 PM EDT
Completed Phase 4 Interventional Results available

Comparative Effectiveness of Split-Dose Colonoscopy Bowel Preparation Regimens

NCT03298945
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Miralax-Gatorade Prep, Golytely
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
2,239 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 5, 2025 · Synced Oct 20, 2026, 9:44 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Cleansing Options in Out-Patient Setting to Improve Tolerance (COOP SIT) Trial

NCT07215000
View directory record Official record
Conditions
Colorectal Cancer Screening, Bowel Cleansing for Colonoscopy
Interventions
Golytely, Sulfave, Sutab
Drug
Lead sponsor
Morehouse School of Medicine
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 9, 2025 · Synced Oct 20, 2026, 9:44 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Residual Gastric Volume in Same Day Versus Split Dose and Evening Before Bowel Preparation

NCT02264249
View directory record Official record
Conditions
Esophagogastroduodenoscopy, Colonoscopy
Interventions
Esophagogastroduodenoscopy and colonoscopy split dose prep, Esophagogastroduodenoscopy and colonoscopy Evening before colonoscopy prep, Esophagogastroduodenoscopy and colonoscopy Same day prep colonoscopy preparation
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
449 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated May 17, 2017 · Synced Oct 20, 2026, 9:44 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Bowel Preparation Quality for Screening Colonoscopy

NCT02690779
View directory record Official record
Conditions
Screening Colonoscopies
Interventions
Educational intervention, Routine Care Instructions
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
45 Years and older
Enrollment
155 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 27, 2017 · Synced Oct 20, 2026, 9:44 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

A Comparison of 5 Low Volume Bowel Preparations

NCT01719653
View directory record Official record
Conditions
Bowel Preparation for Colonoscopy
Interventions
MiraLAX, Gatorade, MoviPrep, SUPREP
Drug · Other
Lead sponsor
Gastroenterology Services, Ltd.
Other
Eligibility
18 Years and older
Enrollment
1,079 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Downers Grove, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 24, 2017 · Synced Oct 20, 2026, 9:44 PM EDT
Recruiting Phase 2 Interventional

High vs.Standard Dose Influenza Vaccine in Pediatric Solid Organ Transplant (SOT) Recipients

NCT05947071
View directory record Official record
Conditions
Immunization; Infection, Transplantation Infection, Influenza
Interventions
Standard Dose Quadrivalent Inactivated Influenza Vaccine, High Dose Quadrivalent Inactivated Influenza Vaccine
Biological
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
3 Years to 17 Years
Enrollment
312 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
10
States / cities
Stanford, California • Atlanta, Georgia • Chicago, Illinois + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 20, 2026, 9:44 PM EDT