- Conditions
- Anterior Cruciate Ligament Reconstruction
- Interventions
- Non-operative treatment group will undergo standardized treatment which will include rehabilitation, bracing and certain activity restrictions, Surgical technique: Transphyseal reconstruction, Surgical technique: Partial transphyseal reconstruction, Surgical technique: Physeal sparing reconstruction by the Anderson method, Surgical technique: Physeal sparing reconstruction by the Micheli/Kocher method
- Other · Procedure
- Lead sponsor
- Boston Children's Hospital
- Other
- Eligibility
- 5 Years to 18 Years
- Enrollment
- 765 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2030
- U.S. locations
- 10
- States / cities
- Palo Alto, California • San Diego, California • Atlanta, Georgia + 7 more
Search Results
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Showing 1–24
of 26
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Anterior Cruciate Ligament Reconstruction
- Interventions
- iovera°
- Device
- Lead sponsor
- Pacira Pharmaceuticals, Inc
- Industry
- Eligibility
- 18 Years to 49 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- ACL Tear
- Interventions
- ACL reconstruction with BTB autograft with internal brace augmentation (suture tape), ACL reconstruction with BTB autograft without internal brace augmentation (suture tape), Standardized Rehabilitation Protocol
- Procedure · Other
- Lead sponsor
- Columbia University
- Other
- Eligibility
- 12 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2032
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Anterior Cruciate Ligament Reconstruction Rehabilitation
- Interventions
- Rehabilitation with Exercise and Psychological Support (REPS)
- Behavioral
- Lead sponsor
- HealthPartners Institute
- Other
- Eligibility
- 15 Years to 21 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Bloomington, Minnesota
- Conditions
- Anterior Cruciate Ligament Injuries, Knee Injuries, Quadriceps Muscle Atrophy
- Interventions
- Blood Flow Restriction using Delfi Personalized Tourniquet System
- Device
- Lead sponsor
- Connecticut Children's Medical Center
- Other
- Eligibility
- 12 Years to 18 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2029
- U.S. locations
- 1
- States / cities
- Farmington, Connecticut
- Conditions
- Anterior Cruciate Ligament Rupture
- Interventions
- Blood Flow Restriction Therapy, ACL Reconstruction rehabilitation
- Device · Other
- Lead sponsor
- Inova Health Care Services
- Other
- Eligibility
- 13 Years to 50 Years
- Enrollment
- 49 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Fairfax, Virginia
- Conditions
- ACL Tear
- Interventions
- Delfi's PTS Personalized Tourniquet System for Blood Flow Restriction Group, Standard ACL rehab
- Device · Other
- Lead sponsor
- Candice Dunkin, MS, LAT, ATC
- Other
- Eligibility
- 16 Years to 22 Years
- Enrollment
- 19 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2025
- U.S. locations
- 1
- States / cities
- Fort Wayne, Indiana
- Conditions
- Anterior Cruciate Ligament Tear
- Interventions
- Delfi, Standard rehabilitation
- Device · Other
- Lead sponsor
- University of Missouri-Columbia
- Other
- Eligibility
- 18 Years to 30 Years
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 1
- States / cities
- Columbia, Missouri
- Conditions
- ACL Tear, Arthrofibrosis, ACL Injury
- Interventions
- Graymont X ERIS Knee Splint, Standard Hinge Knee Brace
- Device
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- 18 Years to 40 Years
- Enrollment
- 21 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- ACL Tear
- Interventions
- NMES and BFR, Standard physical therapy
- Other
- Lead sponsor
- Stanford University
- Other
- Eligibility
- 13 Years to 17 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Sunnyvale, California
- Conditions
- Anterior Cruciate Ligament Injury
- Interventions
- Neuromuscular Electrical Stimulation (NMES), Eccentric Exercise (ECC), Neuromuscular Electrical Stimulation (NMES) placebo, Eccentric Exercise (ECC) placebo
- Device · Other
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 14 Years to 45 Years
- Enrollment
- 135 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2025
- U.S. locations
- 2
- States / cities
- Ann Arbor, Michigan
- Conditions
- Anterior Cruciate Ligament Injuries
- Interventions
- blood flow restriction, physical therapy standard of care
- Other
- Lead sponsor
- University of Arkansas
- Other
- Eligibility
- 18 Years to 34 Years
- Enrollment
- 2 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Little Rock, Arkansas
- Conditions
- Knee Osteoarthristis, ACL Injuries, Post-Traumatic
- Interventions
- extracorporeal shockwave therapy (ESWT), Sham Comparator
- Device
- Lead sponsor
- Spaulding Rehabilitation Hospital
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 70 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Cambridge, Massachusetts
- Conditions
- Anterior Cruciate Ligament Rupture
- Interventions
- Blood Flow Restriction using Delfi Personalized Tourniquet System
- Device
- Lead sponsor
- Children's Healthcare of Atlanta
- Other
- Eligibility
- 12 Years to 18 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- Atlanta, Georgia
- Conditions
- Knee Injuries, Anterior Cruciate Ligament Injuries
- Interventions
- Blood Flow Restriction Therapy, Standard Postoperative Physical Therapy
- Other
- Lead sponsor
- Stanford University
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Redwood City, California
- Conditions
- Anterior Cruciate Ligament Reconstruction
- Interventions
- Body Weight Supported Treadmill Use of Patients with ACL Reconstruction
- Other
- Lead sponsor
- Nationwide Children's Hospital
- Other
- Eligibility
- Not listed
- Enrollment
- 5 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015
- U.S. locations
- 1
- States / cities
- Westerville, Ohio
- Conditions
- Pain and Anterior Cruciate Ligament Reconstruction
- Interventions
- Dry needling and STM
- Other
- Lead sponsor
- Keller Army Community Hospital
- Federal
- Eligibility
- 18 Years to 40 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- West Point, New York
- Conditions
- Blood Flow Restriction, ACL Tear, ACL Injury
- Interventions
- Blood Flow Restriction using Delfi Personalized Tourniquet System
- Device
- Lead sponsor
- Connecticut Children's Medical Center
- Other
- Eligibility
- 12 Years to 18 Years
- Enrollment
- 47 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- Farmington, Connecticut
- Conditions
- Anterior Cruciate Ligament Injury
- Interventions
- Electrical Stimulation, Eccentric Exercise
- Device · Other
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 14 Years to 35 Years
- Enrollment
- 43 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2014
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- ACL Injury
- Interventions
- Blood Flow Restriction (BFR) therapy, Standard REHAB
- Other
- Lead sponsor
- Brooke Army Medical Center
- Federal
- Eligibility
- 15 Years to 45 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
- Conditions
- Rehabilitation, ACL Reconstruction
- Interventions
- HOME, TNMT
- Other
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 13 Years to 30 Years
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2024
- U.S. locations
- 4
- States / cities
- Flowery Branch, Georgia • Minneapolis, Minnesota • Rochester, Minnesota + 1 more
- Conditions
- Anterior Cruciate Ligament Injury, Knee Injury
- Interventions
- Standard Plyometric Training, Plyometric Training with BWS
- Procedure
- Lead sponsor
- University of Montana
- Other
- Eligibility
- 12 Years to 35 Years
- Enrollment
- 47 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2018
- U.S. locations
- 1
- States / cities
- Missoula, Montana
- Conditions
- Anterior Cruciate Ligament Reconstruction, Volumetric Muscle Loss, Chronic Thigh Muscle Weakness, Knee Arthroscopy
- Interventions
- Blood Flow Restriction (BFR) Training, Standard ACSM-guided strength training
- Other
- Lead sponsor
- Brooke Army Medical Center
- Federal
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2017
- U.S. locations
- 2
- States / cities
- Fort Sam Houston, Texas
- Conditions
- Osteoarthritis, Knee, Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, Quadriceps Muscle Atrophy
- Interventions
- Experimental: Whole Body Vibration, Experimental: Local Muscle Vibration, Standard ACL Rehabilitation
- Device · Other
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 16 Years to 35 Years
- Enrollment
- 114 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2026
- U.S. locations
- 2
- States / cities
- Chapel Hill, North Carolina