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ClinicalTrials.gov public records Last synced Oct 25, 2026, 7:33 PM EDT

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Showing 1–24 of 79 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Standard Atrial fibrillation ablation Clear all
Recruiting Not applicable Interventional

Artificial Intelligence Mapping and Ablation of Non-Pulmonary Vein Electrical Drivers of AF Study

NCT06935591
View directory record Official record
Conditions
Atrial Fibrillation (AF)
Interventions
Pulmonary Vein Isolation, vMap® + Pulmonary Vein Isolation
Procedure · Device
Lead sponsor
Vektor Medical
Industry
Eligibility
22 Years and older
Enrollment
423 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
12
States / cities
Jonesboro, Arkansas • Clearwater, Florida • Jacksonville, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Oct 25, 2026, 7:33 PM EDT
Completed Not applicable Interventional Results available

Randomized Evaluation of Atrial Fibrillation Treatment With Focal Impulse and Rotor Modulation Guided Procedures

NCT02274857
View directory record Official record
Conditions
Persistent Atrial Fibrillation
Interventions
Standard PVI Ablation, FIRM-Guided Procedure and PVI
Procedure
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years to 80 Years
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
10
States / cities
Phoenix, Arizona • Newport Beach, California • Maywood, Illinois + 6 more
Source: ClinicalTrials.gov public record
Updated Feb 7, 2020 · Synced Oct 25, 2026, 7:33 PM EDT
Completed No phase listed Observational

Implantable Loop Recorders in Post-atrial Fibrillation (AF) Ablation: RPAF-A

NCT01061125
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
TTM and Holter monitor
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 100 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 10, 2017 · Synced Oct 25, 2026, 7:33 PM EDT
Completed No phase listed Observational

Novel Cardiac Signal Processing System

NCT04112433
View directory record Official record
Conditions
Cardiac Arrhythmia
Interventions
PURE EP 2
Device
Lead sponsor
BioSig Technologies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
3
States / cities
Jacksonville, Florida • Boston, Massachusetts • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Feb 11, 2022 · Synced Oct 25, 2026, 7:33 PM EDT
Terminated Not applicable Interventional

Necessity of Anti-Arrhythmic Medication After Surgical Ablation for Atrial Fibrillation

NCT01416935
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
No Amiodarone
Other
Lead sponsor
Inova Health Care Services
Other
Eligibility
18 Years and older
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Falls Church, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 20, 2022 · Synced Oct 25, 2026, 7:33 PM EDT
Recruiting No phase listed Observational

REPRESENT-PF Registry

NCT07535268
View directory record Official record
Conditions
Persistent Atrial Fibrillation, Paroxysmal Atrial Fibrillation
Interventions
FARAWAVE Pulsed Field Ablation Catheter
Device
Lead sponsor
Vivek Reddy
Other
Eligibility
18 Years and older
Enrollment
275 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
New York, New York • Winchester, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 17, 2026 · Synced Oct 25, 2026, 7:33 PM EDT
Completed Not applicable Interventional Results available

Randomized Evaluation of Redo Ablation Procedures of Atrial Fibrillation With FIRM Guided Procedures

NCT02799043
View directory record Official record
Conditions
Persistent Atrial Fibrillation, Paroxysmal Atrial Fibrillation
Interventions
Standard PVI, FIRM-Guided Procedure and PVI
Procedure
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years to 80 Years
Enrollment
269 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
12
States / cities
Phoenix, Arizona • Ventura, California • Fort Lauderdale, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 25, 2026, 7:33 PM EDT
Active, not recruiting No phase listed Observational

Acute Cognitive Changes During Atrial Fibrillation Episodes (AFCOG)

NCT04033510
View directory record Official record
Conditions
Atrial Fibrillation, Cognitive Symptom, Executive Dysfunction, Cognitive Change, Cognitive Impairment, Cognitive Impairment, Mild
Interventions
Standard of Care Interventions to convert patient from atrial fibrillation to normal rhythm
Other
Lead sponsor
David Brunk, PA-C, MMS
Other
Eligibility
35 Years to 80 Years
Enrollment
600 participants
Timeline
2019 – 2027
U.S. locations
1
States / cities
Colorado Springs, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Oct 25, 2026, 7:33 PM EDT
Completed Phase 3 Interventional

Renal Artery Denervation In Addition to Catheter Ablation To Eliminate Atrial Fibrillation

NCT01873352
View directory record Official record
Conditions
Atrial Fibrillation, Hypertension
Interventions
catheter ablation, renal sympathetic denervation
Procedure
Lead sponsor
Meshalkin Research Institute of Pathology of Circulation
Network
Eligibility
18 Years to 75 Years
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Short Hills, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 4, 2019 · Synced Oct 25, 2026, 7:33 PM EDT
Terminated Not applicable Interventional

Bariatric Atrial Restoration of Sinus Rhythm

NCT04050969
View directory record Official record
Conditions
Atrial Fibrillation, Morbid Obesity
Interventions
Bariatric surgery, Atrial Fibrillation (AF) Catheter Ablation
Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 70 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Oct 19, 2022 · Synced Oct 25, 2026, 7:33 PM EDT
Completed Not applicable Interventional

ICE: Intracardiac Ultrasound Within the Left Atrium During Radiofrequency Ablation of Nonvalvular Atrial Fibrillation

NCT02028143
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Biosense Webster irrigated tip catheter, Pulmonary vein isolation, ICE catheter placed through one of two existing 8F sheaths
Device · Procedure
Lead sponsor
Gregory Jones
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Kingsport, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 24, 2018 · Synced Oct 25, 2026, 7:33 PM EDT
Recruiting Not applicable Interventional

Comparison of Two Pulse Field Ablation Systems for AF Ablation

NCT07883629
View directory record Official record
Conditions
AF - Atrial Fibrillation
Interventions
Pulse Field Ablation
Procedure
Lead sponsor
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Other
Eligibility
18 Years to 89 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 25, 2026, 7:33 PM EDT
Completed Not applicable Interventional Results available

General Anesthesia With ETT vs LMA in Patients Undergoing Ablation for Atrial Fibrillation

NCT02896595
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
General Anesthesia with endotracheal tube, General Anesthesia with laryngeal mask airway
Device
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 99 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 21, 2020 · Synced Oct 25, 2026, 7:33 PM EDT
Active, not recruiting Not applicable Interventional

RESOLVE-AF: Clinical Evaluation of the Ablacath™ Mapping Catheter and Ablamap® System Utilizing Electrographic Flow (EGF) Mapping to Resolve Extra-PV Sources of Atrial Fibrillation and Guide Ablation Therapy.

NCT05883631
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Fibrillation, Persistent, Atrial Fibrillation Paroxysmal, Arrhythmia, Arrhythmias, Cardiac, Atrial Flutter, Atrial Fibrillation, Paroxysmal or Persistent, Atrial Arrhythmia, Atrial Tachycardia
Interventions
Electrographic Flow (EGF) mapping and ablation of EGF-identified sources of Atrial Fibrillation, Electrographic Flow (EGF) mapping (no ablation)
Device
Lead sponsor
Cortex
Industry
Eligibility
18 Years to 80 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
15
States / cities
Birmingham, Alabama • Phoenix, Arizona • Redwood City, California + 11 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2025 · Synced Oct 25, 2026, 7:33 PM EDT
Completed Phase 3 Interventional Results available

Vein of Marshall Ethanol Infusion for Persistent Atrial Fibrillation

NCT01898221
View directory record Official record
Conditions
Ventricular Tachycardia, Atrial Fibrillation
Interventions
Ethanol, Ablation
Drug · Procedure
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years to 85 Years
Enrollment
343 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
12
States / cities
Phoenix, Arizona • Los Angeles, California • San Diego, California + 7 more
Source: ClinicalTrials.gov public record
Updated Aug 21, 2025 · Synced Oct 25, 2026, 7:33 PM EDT
Terminated Not applicable Interventional

Focal Impulse and Rotor Modulation Ablation Trial for Treatment of Paroxysmal Atrial Fibrillation (FIRMAT-PAF)

NCT01925885
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation
Interventions
PVI Ablation, FIRM Ablation
Procedure
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 80 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 5, 2017 · Synced Oct 25, 2026, 7:33 PM EDT
Completed Not applicable Interventional

Pulmonary Vein Isolation in Athletes

NCT03226847
View directory record Official record
Conditions
Athletes, Atrial Fibrillation, Catheter Ablation
Interventions
Pulmonary Vein Isolation
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 13, 2021 · Synced Oct 25, 2026, 7:33 PM EDT
Completed No phase listed Observational

Clinical Utility and Validation of the Rhythmia Mapping System for the Treatment of Cardiac Arrhythmias

NCT03094221
View directory record Official record
Conditions
Cardiac Arrhythmias, Electroanatomic Mapping, Cardiac Ablation
Interventions
Rhythmia Mapping System
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 29, 2017 · Synced Oct 25, 2026, 7:33 PM EDT
Not listed Not applicable Interventional

Left Atrial Posterior Wall and PV Isolation Using Cryoballoon for Treatment of Persistent AF

NCT04505163
View directory record Official record
Conditions
Persistent Atrial Fibrillation
Interventions
Standard Cryoballoon Pulmonary Vein Isolation (PVI), Cryoballoon PVI + Posterior Wall Isolation
Procedure · Device
Lead sponsor
Dignity Health Medical Foundation
Other
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
11
States / cities
Sacramento, California • Fort Collins, Colorado • Washington D.C., District of Columbia + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 6, 2023 · Synced Oct 25, 2026, 7:33 PM EDT
Active, not recruiting Not applicable Interventional

STrategies for Catheter Ablation of peRsistent Atrial Fibrlllation

NCT04428944
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Wide Circumferential Pulmonary Vein Antrum Isolation (PVAI), Pulmonary Vein Antrum Isolation Plus Driver Ablation (PVAI+drivers), Pulmonary Vein Antrum Isolation Plus Box Isolation of Posterior Wall (PVAI+box)
Procedure
Lead sponsor
McGill University Health Centre/Research Institute of the McGill University Health Centre
Other
Eligibility
18 Years and older
Enrollment
617 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 25, 2026, 7:33 PM EDT
Terminated No phase listed Observational

Release of Acetylcholine From the Ganglionated Plexus During the Thaw Phase of Cryoballon Pulmonary Vein Ablation (GP RESPONSE Study)

NCT03636100
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Cryoballoon ablation
Device
Lead sponsor
Saint Luke's Health System
Other
Eligibility
18 Years to 80 Years
Enrollment
7 participants
Timeline
2018 – 2019
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 19, 2021 · Synced Oct 25, 2026, 7:33 PM EDT
Terminated No phase listed Observational

All Inclusive Kodex - EPD Study

NCT05489445
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
KODEX - EPD
Device
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 15, 2023 · Synced Oct 25, 2026, 7:33 PM EDT
Completed Not applicable Interventional

Outcome of Atrial Fibrillation Ablation After Permanent Pulmonary Vein Antrum Isolation With or Without Proven Left Atrial Posterior Wall Isolation

NCT01660100
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Pulmonary vein antrum isolation (PVAI), PVAI plus left atrial posterior wall (LAPW) isolation
Procedure
Lead sponsor
Texas Cardiac Arrhythmia Research Foundation
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Oct 19, 2017 · Synced Oct 25, 2026, 7:33 PM EDT
Terminated Not applicable Interventional

Radiofrequency (RF) Ablation for Atrial Fibrillation (AF) in Patients With Heart Failure With Preserved Ejection Fraction

NCT04327596
View directory record Official record
Conditions
Heart Failure With Preserved Ejection Fraction
Interventions
RF ablation of AF using CARTO 3 and a Thermocool ST SF ablation catheter
Procedure
Lead sponsor
University of Rochester
Other
Eligibility
50 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
2
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Feb 23, 2022 · Synced Oct 25, 2026, 7:33 PM EDT