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ClinicalTrials.gov public records Last synced Sep 5, 2026, 11:36 PM EDT

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Showing 1–24 of 33 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Standard CPAP Intervention Clear all
Recruiting Not applicable Interventional

Neurocognitive and Health Impact of Sleep Apnea in Elderly Veterans With Comorbid COPD

NCT02703207
View directory record Official record
Conditions
Obstructive Sleep Apnea, OSA COPD Overlap Syndrome
Interventions
Positive airway pressure, NIPPV and /or oxygen
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
60 Years to 89 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated May 25, 2026 · Synced Sep 5, 2026, 11:36 PM EDT
Completed Not applicable Interventional Results available

Early Treatment of Amyotrophic Lateral Sclerosis (ALS) With Nutrition and Non-Invasive Positive Pressure Ventilation

NCT00116558
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis
Interventions
Early NIPPV, Standard NIPPV
Device
Lead sponsor
Edward Kasaraskis
Other
Eligibility
18 Years to 80 Years
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2012
U.S. locations
12
States / cities
Denver, Colorado • Miami, Florida • Lexington, Kentucky + 8 more
Source: ClinicalTrials.gov public record
Updated Jul 30, 2019 · Synced Sep 5, 2026, 11:36 PM EDT
Completed Not applicable Interventional

MonitAir Remote Patient Monitoring Versus Standard of Care for CPAP Adherence in Obstructive Sleep Apnea

NCT07182617
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Standard Coaching (SOC), MonitAir RPM
Behavioral
Lead sponsor
MonitAir
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Sep 5, 2026, 11:36 PM EDT
Completed Not applicable Interventional

Continous Positive Airway Pressure (CPAP) Compliance Study

NCT01642160
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
additional educational material, Standard of care
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 6, 2013 · Synced Sep 5, 2026, 11:36 PM EDT
Completed Not applicable Interventional Results available

Home-Based Diagnosis and Management of Sleep-Related Breathing Disorders in Spinal Cord Injury

NCT01882257
View directory record Official record
Conditions
Obstructive Sleep Apnea, Hypercapnia, Spinal Cord Injury
Interventions
BiPAP, BiPAP/AVAPS (Phillips Respironics)
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 10, 2017 · Synced Sep 5, 2026, 11:36 PM EDT
Not listed Not applicable Interventional

Peer-Driven Intervention for Sleep Apnea

NCT02056002
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Usual Care, Peer-Buddy System
Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 85 Years
Enrollment
362 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 4, 2017 · Synced Sep 5, 2026, 11:36 PM EDT
Not yet recruiting Not applicable Interventional

KPAP Adherence Crossover Study

NCT06413134
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
KPAP, APAP
Device
Lead sponsor
SleepRes Inc.
Industry
Eligibility
20 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Murfreesboro, Tennessee
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 5, 2026, 11:36 PM EDT
Recruiting Not applicable Interventional

Bilevel Positive Airway Pressure (BPAP) for Severe Asthma

NCT07582211
View directory record Official record
Conditions
Pediatric Asthma, Acute Asthma, BiPAP, Non-invasive Positive Pressure Ventilation
Interventions
Bilevel positive airway pressure ventilation
Device
Lead sponsor
Columbia University
Other
Eligibility
5 Years to 17 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
3
States / cities
New York, New York • Columbus, Ohio • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 5, 2026, 11:36 PM EDT
Recruiting Not applicable Interventional

Stroke and CPAP Outcome Study 3 Randomized Controlled Trial

NCT06722755
View directory record Official record
Conditions
Stroke Patients, CPAP, OSA - Obstructive Sleep Apnea
Interventions
CPAP device, CPAP technical support, Phone follow-up for adherence feedback and self-management skills, myAir, Tailored messages, Written Materials, Motivational Enhancement Therapy (MET)
Device · Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Downey, California • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Sep 5, 2026, 11:36 PM EDT
Withdrawn Not applicable Interventional

Comparison of High-flow Oxygen With or Without Nasal Positive Airway Pressure (PAP) During Propofol Sedation for Colonoscopy in an Ambulatory Surgical Center

NCT05754255
View directory record Official record
Conditions
Colonoscopy, Positive-Pressure Respiration
Interventions
Nasal Cannula, Nasal Positive Airway Pressure System
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Sep 5, 2026, 11:36 PM EDT
Completed No phase listed Observational

Prematurity-Related Ventilatory Control

NCT03464396
View directory record Official record
Conditions
Respiratory Control in Premature Infants
Interventions
Bedside Physiology study, Carotid Body Function Test, Room Air Challenge, Hypoxia Challenge Test, Effects of Nasal Cannula Flow, Magnetic Resonance Imaging, Echocardiogram, Blood Sample
Other · Diagnostic Test
Lead sponsor
Washington University School of Medicine
Other
Eligibility
1 Day to 28 Days
Enrollment
177 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 30, 2023 · Synced Sep 5, 2026, 11:36 PM EDT
Terminated Not applicable Interventional Results available

A Pilot Study to Assess the Effects of a Novel Application of Averaged Volume Assured Pressure Support Ventilation (AVAPS-AE) Therapy on Re-hospitalization in Patients With Sleep-Disordered Breathing With Co-morbid COPD

NCT02446769
View directory record Official record
Conditions
Breathing-Related Sleep Disorder
Interventions
AVAPS-AE Non-invasive ventilation therapy
Device
Lead sponsor
Philips Respironics
Industry
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 4, 2020 · Synced Sep 5, 2026, 11:36 PM EDT
Completed Not applicable Interventional Results available

A Pilot Study of Biomarkers in Obstructive Sleep Apnea

NCT02325687
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Lumbar Puncture (Standard-of-Care)
Procedure
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
50 Years to 84 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 20, 2020 · Synced Sep 5, 2026, 11:36 PM EDT
Terminated Not applicable Interventional Results available

MRI Only Radiation Therapy With CPAP

NCT03397342
View directory record Official record
Conditions
Carcinoma Liver, Carcinoma, Pancreatic
Interventions
CPAP machine
Device
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jan 17, 2024 · Synced Sep 5, 2026, 11:36 PM EDT
Completed Phase 1Phase 2 Interventional

Delivery Room CPAP in Extremely Low Birth Weight Infants

NCT01223274
View directory record Official record
Conditions
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Bronchopulmonary Dysplasia, Continuous Positive Airway Pressure
Interventions
CPAP/PEEP, Standard management practices
Device
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 10 Minutes
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2003
U.S. locations
6
States / cities
Birmingham, Alabama • San Diego, California • Miami, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Sep 5, 2026, 11:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Nasal Continuous Positive Airway Pressure Versus Standard Care During Procedural Sedation for Gastrointestinal Endoscopy

NCT03369197
View directory record Official record
Conditions
Hypoxia, Endoscopy, Anesthesia Morbidity
Interventions
Nasal Mask, Control: Nasal Cannula
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
111 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 17, 2022 · Synced Sep 5, 2026, 11:36 PM EDT
Completed Phase 1 Interventional Results available

Tailored Intervention to Promote Positive Airway Pressure Adherence

NCT01454830
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Patient Compliance
Interventions
Tailored, Usual care
Behavioral · Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 22, 2016 · Synced Sep 5, 2026, 11:36 PM EDT
Completed Not applicable Interventional

Trial of Non-invasive Ventilation for Stable COPD

NCT01722773
View directory record Official record
Conditions
COPD
Interventions
Bipap (Respironics, Inc)
Device
Lead sponsor
University of Iowa
Other
Eligibility
35 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 6, 2012 · Synced Sep 5, 2026, 11:36 PM EDT
Recruiting Not applicable Interventional

The Improving Sleep in African American Couples Study (ISAAC)

NCT07447284
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
CPAP Training and Education, Virtual Disease Support Group Sessions, Couple CPAP Training and Education, Couples Virtual OSA Support Group Sessions, CPAP Tele-monitoring and Feedback, Couples' Cognitive Behavioral Therapy
Behavioral
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
30 Years and older
Enrollment
440 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Cleveland, Ohio • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Sep 5, 2026, 11:36 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Impact of Early Diagnosis and Treatment of OSA on Hospital Readmission in Hospitalized COPD Patients

NCT03647462
View directory record Official record
Conditions
Obstructive Sleep Apnea, Chronic Obstructive Pulmonary Disease
Interventions
Continuous Positive Airway Pressure
Device
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Fontana, California
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Sep 5, 2026, 11:36 PM EDT
Not listed Phase 4 Interventional

OPTIMIST-A Trial: Minimally-invasive Surfactant Therapy in Preterm Infants 25-28 Weeks Gestation on CPAP

NCT02140580
View directory record Official record
Conditions
Bronchopulmonary Dysplasia
Interventions
Minimally invasive surfactant therapy, Continuation on CPAP
Device · Other
Lead sponsor
Menzies Institute for Medical Research
Other
Eligibility
1 Minute to 6 Hours
Enrollment
486 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2022
U.S. locations
5
States / cities
New Haven, Connecticut • Honolulu, Hawaii • Evanston, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 30, 2020 · Synced Sep 5, 2026, 11:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prophylactic DR-CPAP on Late Preterm Infants Born by C-section: an RCT

NCT05204719
View directory record Official record
Conditions
Premature Birth
Interventions
Prophylactic Delivery Room Continuous Positive Airway Pressure
Procedure
Lead sponsor
University of Oklahoma
Other
Eligibility
1 Minute to 5 Minutes
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
3
States / cities
Indianapolis, Indiana • St Louis, Missouri • Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Sep 5, 2026, 11:36 PM EDT
Completed Not applicable Interventional

High Flow Nasal Cannula With Noninvasive Ventilation

NCT04507425
View directory record Official record
Conditions
Acute Respiratory Failure
Interventions
Standard of Care - Nasal Cannula, High-flow nasal cannula, HFNC plus non-invasive ventilation
Other
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 100 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Nov 20, 2023 · Synced Sep 5, 2026, 11:36 PM EDT
Completed Not applicable Interventional

ThErapy Adherence Management in Veterans

NCT03243487
View directory record Official record
Conditions
Obstructive Sleep Apnea of Adult
Interventions
structured adherence management program, Standard of care
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 85 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
2
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 12, 2019 · Synced Sep 5, 2026, 11:36 PM EDT