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Showing 1–24 of 28 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Standard CPR Clear all
Recruiting Phase 1 Interventional

Hydrogen's Feasibility and Safety as a Therapy in ECPR

NCT05574296
View directory record Official record
Conditions
Cardiac Arrest, Extracorporeal Membrane Oxygenation, Reperfusion Injury
Interventions
Hydrogen, Usual care
Drug · Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Not listed
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
4
States / cities
Washington D.C., District of Columbia • Boston, Massachusetts • Kansas City, Missouri + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 2, 2025 · Synced Sep 6, 2026, 8:28 AM EDT
Recruiting No phase listed Observational

Quality of Pediatric Resuscitation in a Multicenter Collaborative

NCT02708134
View directory record Official record
Conditions
Cardiac Arrest, Cardiopulmonary Arrest
Interventions
Not listed
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
0 Years to 18 Years
Enrollment
7,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2030
U.S. locations
40
States / cities
Los Angeles, California • Madera, California • Orange, California + 32 more
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Sep 6, 2026, 8:28 AM EDT
Active, not recruiting Not applicable Interventional

Situation Awareness Incorporating Multidisciplinary Teams Reduce Arrests In the Pediatric ICU

NCT06553534
View directory record Official record
Conditions
In-hospital Cardiac Arrest, Cardiopulmonary Resuscitation
Interventions
SAMURAI PICU Bundle
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Not listed
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
5
States / cities
Chicago, Illinois • Akron, Ohio • Charleston, South Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 15, 2024 · Synced Sep 6, 2026, 8:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Self-directed Video Versus Instructor-based Neonatal Resuscitation Training

NCT01847911
View directory record Official record
Conditions
Resuscitation of Newborn Training
Interventions
Self instructed video learning, instructor training
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 70 Years
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
3
States / cities
New York, New York • Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Feb 20, 2021 · Synced Sep 6, 2026, 8:28 AM EDT
Terminated Phase 3 Interventional

AutoPulse Assisted Prehospital International Resuscitation Trial (ASPIRE)

NCT00120965
View directory record Official record
Conditions
Cardiac Arrest
Interventions
AutoPulse, Manual CPR
Device · Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
1,837 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 26, 2011 · Synced Sep 6, 2026, 8:28 AM EDT
Completed Phase 1 Interventional

Trial of Vasopressin and Epinephrine to Epinephrine Only for In-Hospital Pediatric Cardiopulmonary Resuscitation

NCT00628550
View directory record Official record
Conditions
Cardiopulmonary Arrest, Cardiac Arrest
Interventions
Vasopressin, Epinephrine
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
Up to 18 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 16, 2019 · Synced Sep 6, 2026, 8:28 AM EDT
Terminated Not applicable Interventional Results available

Advanced Reperfusion Strategies for Refractory Cardiac Arrest

NCT03880565
View directory record Official record
Conditions
Cardiac Arrest, Extracorporeal Membrane Oxygenation Complication, Ventricular Fibrillation, Pulseless Ventricular Tachycardia, Out-Of-Hospital Cardiac Arrest
Interventions
Early Extracorporeal Membrane Oxygenation (ECMO) Facilitated Resuscitation, Standard Advanced Cardiac Life Support (ACLS) Resuscitation
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 9, 2022 · Synced Sep 6, 2026, 8:28 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Gathering Evidence on Best Practices for Lay Rescuer CPR Training

NCT05908500
View directory record Official record
Conditions
Cardiac Arrest, Out-Of-Hospital
Interventions
CPR Training, CPR Manikin Type
Behavioral · Device
Lead sponsor
University of Nevada, Reno
Other
Eligibility
Not listed
Enrollment
2,100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
Reno, Nevada
Source: ClinicalTrials.gov public record
Updated Jun 3, 2025 · Synced Sep 6, 2026, 8:28 AM EDT
Not yet recruiting Not applicable Interventional

PRECISION-CPR: PRecision-Controlled Ventilation in CPR

NCT07088120
View directory record Official record
Conditions
Cardiac Arrest (CA)
Interventions
Precision-Controlled Ventilation with Real-Time Feedback, Standard Manual Ventilation During CPR
Device · Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
852 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Sep 6, 2026, 8:28 AM EDT
Completed Phase 4 Interventional Results available

Continuous Chest Compressions vs AHA Standard CPR of 30:2

NCT01372748
View directory record Official record
Conditions
Out of Hospital Cardiac Arrest
Interventions
Standard CPR, Continuous chest compressions
Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
23,711 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
5
States / cities
Birmingham, Alabama • Pittsburgh, Pennsylvania • Dallas, Texas + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 27, 2016 · Synced Sep 6, 2026, 8:28 AM EDT
Recruiting Not applicable Interventional

Optimal Ventilation for Cardiac Arrest

NCT07114510
View directory record Official record
Conditions
Cardiac Arrest (CA)
Interventions
OPTI-VENT Bundle, Transition, None - control
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
37 Weeks to 18 Years
Enrollment
1,530 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
20
States / cities
Orange, California • Palo Alto, California • Denver, Colorado + 16 more
Source: ClinicalTrials.gov public record
Updated Oct 7, 2025 · Synced Sep 6, 2026, 8:28 AM EDT
Active, not recruiting Not applicable Interventional

RACE-CARS - RAndomized Cluster Evaluation of Cardiac ARrest Systems

NCT04660526
View directory record Official record
Conditions
Cardiac Arrest
Interventions
Rapid cardiac arrest recognition that triggers immediate priority EMS/first responder dispatch by 911 operators, Systematic bystander resuscitation instruction by 911 operators, Comprehensive community training of lay people in CPR and AED use., Optimized first responder performance including earlier use of AEDs.
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
20,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Sep 6, 2026, 8:28 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Cardiopulmonary Resuscitation (CPR) Dissemination Study Using Nurses and Volunteers

NCT01252316
View directory record Official record
Conditions
Cardiovascular Risk Factors, Coronary Disease, Cardiac Arrest
Interventions
CPR Training using the Family and Friends CPR Anytime VSI Kit, Implementation of an In-Hospital CPR Training Model
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 31, 2018 · Synced Sep 6, 2026, 8:28 AM EDT
Active, not recruiting Not applicable Interventional

The Feasibility of Using the PulsePoint to Facilitate Overdose Education and Naloxone Distribution

NCT06523985
View directory record Official record
Conditions
Carrying Naloxone/Narcan on Their Person or in Their Vehicle, Being Trained to Respond to an Opioid Overdose
Interventions
Push messages (standard), Push messages (customized)
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
Not listed
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Sep 6, 2026, 8:28 AM EDT
Completed Not applicable Interventional Results available

Hemodynamic Effects of Standard Cardiopulmonary Resuscitation (CPR), Active Compression Decompression CPR With an Inspiratory Impedance Device, and Standard CPR With an Intrathoracic Pressure Regulator During Out-of-hospital Cardiac Arrest

NCT01325870
View directory record Official record
Conditions
Cardiac Arrest, Sudden Cardiac Death
Interventions
ACD-CPR, ITPR, S-CPR, Impedance Threshold Device (ITD)
Device · Procedure
Lead sponsor
Advanced Circulatory Systems
Industry
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Kalamazoo, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 11, 2016 · Synced Sep 6, 2026, 8:28 AM EDT
Completed Not applicable Interventional

A Universal Electronic Health Record-based IMPROVE DD VTE Risk Assessment Model for the Prevention of Thromboembolism in Hospitalized Medically Ill Patients

NCT04768036
View directory record Official record
Conditions
Venous Thromboembolism, Arterial Thromboembolism
Interventions
IMPROVE DD VTE Tool
Other
Lead sponsor
Northwell Health
Other
Eligibility
60 Years and older
Enrollment
10,699 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
5
States / cities
Manhasset, New York • New Hyde Park, New York • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 1, 2022 · Synced Sep 6, 2026, 8:28 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

An In-Hospital Family Member Cardiopulmonary Resuscitation (CPR) Education Program

NCT01260441
View directory record Official record
Conditions
Cardiac Arrest, Coronary Disease, Cardiovascular Risk Factors
Interventions
CPR Training using the Family and Friends CPR Anytime VSI Kit
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
3
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 31, 2018 · Synced Sep 6, 2026, 8:28 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Choice of Diction's Effect

NCT04896411
View directory record Official record
Conditions
Communication, Advance Directives, Decision Making, Cardiopulmonary Resuscitation
Interventions
Alternative phrasing for no code, Standard of care for no code
Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
65 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 24, 2022 · Synced Sep 6, 2026, 8:28 AM EDT
Terminated Not applicable Interventional Results available

ResQ Trial: Impact of an ITD and Active Compression Decompression CPR on Survival From Out-of-Hospital Cardiac Arrest

NCT00189423
View directory record Official record
Conditions
Heart Arrest, Death, Sudden, Cardiac, Cardiopulmonary Resuscitation, Cardiac Arrest
Interventions
Use of an impedance threshold device (ITD) during the performance of active compression decompression CPR (ACD-CPR), Standard cardiopulmonary resuscitation (S-CPR)
Device · Procedure
Lead sponsor
Advanced Circulatory Systems
Industry
Eligibility
18 Years and older
Enrollment
1,653 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
7
States / cities
Indianapolis, Indiana • Ann Arbor, Michigan • Royal Oak, Michigan + 4 more
Source: ClinicalTrials.gov public record
Updated Dec 7, 2017 · Synced Sep 6, 2026, 8:28 AM EDT
Completed Not applicable Interventional

Prompt Diagnosis and Treatment of Subclinical Seizures After Cardiac Arrest

NCT02458820
View directory record Official record
Conditions
Heart Arrest, Seizures
Interventions
DSA EEG
Procedure
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
2 Days and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 8, 2019 · Synced Sep 6, 2026, 8:28 AM EDT
Completed Not applicable Interventional Results available

ECPR for Refractory Out-Of-Hospital Cardiac Arrest

NCT03065647
View directory record Official record
Conditions
Cardiac Arrest, Heart Arrest, Sudden Cardiac Arrest, Cardiopulmonary Arrest, Death, Sudden, Cardiac, Cardiopulmonary Resuscitation, CPR, Extracorporeal Cardiopulmonary Resuscitation, Extracorporeal Membrane Oxygenation
Interventions
Expedited Transport With Mechanical CPR
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 2, 2021 · Synced Sep 6, 2026, 8:28 AM EDT
Completed Not applicable Interventional

Default Options in Advance Directives

NCT02017548
View directory record Official record
Conditions
This Study Will Focus on Advance Care Planning Among Patients With Life-limiting Illnesses
Interventions
Life-extension default advance directive, Comfort default advance directive
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
4
States / cities
Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 31, 2019 · Synced Sep 6, 2026, 8:28 AM EDT
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers

Door-Through-Door Companion Rideshare Technology for Individuals With Alzheimer's Disease and Related Dementias (AD/ADRD)

NCT06850870
View directory record Official record
Conditions
Alzheimer Disease or Associated Disorder, Dementia, Cognitive Decline
Interventions
Door-through-door companion rideshare, Curb-to-curb rideshare services
Other
Lead sponsor
Onward Health, Inc
Industry
Eligibility
60 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Leandro, California
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Sep 6, 2026, 8:28 AM EDT
Completed Not applicable Interventional

The ICU-Resuscitation Project (ICU-RESUS)

NCT02837497
View directory record Official record
Conditions
Cardiac Arrest
Interventions
ICU-RESUS CPR Improvement Bundle
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
37 Weeks to 18 Years
Enrollment
1,127 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 16, 2021 · Synced Sep 6, 2026, 8:28 AM EDT