Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 13, 2026, 3:03 AM EDT

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Showing 1–14 of 14 matching trials from the live ClinicalTrials.gov search.
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Conditions
Concussion, Brain, Near Point Convergence
Interventions
Brock String Therapy, Standard of Care
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years to 20 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Concussion, Mild, Mild Traumatic Brain Injury (mTBI), Psychological Health
Interventions
Acceptance and Commitment Therapy Integrated Rehabilitation (ACT), Usual Care Rehabilitation
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 49 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • Fort Hood, Texas
Conditions
Persistent Post-concussive Symptoms, Post Traumatic Headache
Interventions
SPINEPASS Physical Therapy, Standard Physical Therapy
Other
Lead sponsor
The University of Queensland
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
San Antonio, Texas
Conditions
Concussion (Diagnosis), Concussion, Mild Traumatic Brain Injury, Treatment, Sleep Health, Depression, Anxiety
Interventions
Sleep Intervention
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
10 Years to 19 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Completed Not applicable Interventional Accepts healthy volunteers

The TRAIN Study: A Concussion Prevention Strategy in Middle Schools

NCT04841473
Conditions
Concussion, Brain
Interventions
TRAIN Concussion Education, Standard Concussion Education
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
103 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Sports-related Concussion
Interventions
Photobiomodulation therapy (PBMt), Standard of Care
Device · Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
13 Years to 18 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Houston, Texas
Conditions
Traumatic Brain Injury
Interventions
STEP, Control
Behavioral
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
14 Years to 22 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Traumatic Brain Injury, Insomnia, Depression, Post-traumatic Stress, Sleep, Memory Impairment, Cognitive Behavioral Therapy, Concussion, Brain, Head Injury, Brain Injury Traumatic Mild
Interventions
Mindfulness-based treatment for insomnia (MBTI), Cognitive behavioral therapy for insomnia (CBT-I)
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
5
States / cities
Eglin Air Force Base, Florida • Bethesda, Maryland • Fort Bragg, North Carolina + 1 more
Conditions
Autonomic Nervous System Disease, Concussive Injury, Mild Traumatic Brain Injury, Post Traumatic Stress Disorder, Persistent Post Concussion Syndrome
Interventions
HRV Coherence Ratio, NSI, Pittsburgh Sleep Quality Index (PSQI), Quantitative Sleep Measures, Patient Global Impression of Change (PGIC), Cognitive Performance/NIH Toolbox Cognitive Battery, Pain Interference/TBI-QoL Pain Interference Short-Form, Patient Health Questionnaire-9 (PHQ-9), PTSD Checklist for DSM-5 (PCL-5), HRV Biofeedback (HRV-B), Psychoeducational (Edu) Comparator Intervention
Other · Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Richmond, Virginia
Recruiting Not applicable Interventional

Problem-Solving Training for Concussion

NCT05837676
Conditions
Brain Concussion
Interventions
Problem Solving Training for Concussion, Treatment as usual
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Buffalo, New York
Conditions
Mild Traumatic Brain Injury, Moderate Traumatic Brain Injury, Mild Cognitive Impairment
Interventions
No Intervention is used for this study but all subjects will be asked to complete electroencephalogram (EEG) testing and an MRI scan., No intervention is used for this study but all subjects will be asked to complete a venous blood draw procedure and a lumbar puncture procedure.
Device · Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
30 Years to 90 Years
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Enrolling by invitation Not applicable Interventional

Positive Assurance and mTBI

NCT04982731
Conditions
MTBI - Mild Traumatic Brain Injury, Concussion, Mild Traumatic Brain Injury
Interventions
Positive Assurance
Other
Lead sponsor
Inova Health Care Services
Other
Eligibility
13 Years to 21 Years
Enrollment
229 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Falls Church, Virginia
Completed Not applicable Interventional

TBI Evaluation and Management (TEaM)

NCT04576715
Conditions
Mild Traumatic Brain Injury
Interventions
TEaM Intervention, Standard of Care
Behavioral
Lead sponsor
Emory University
Other
Eligibility
5 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
3
States / cities
Atlanta, Georgia
Recruiting Not applicable Interventional

GyroStim for Post Concussion Syndrome

NCT07527663
Conditions
Post Concussion Syndrome
Interventions
Sensorimotor Multi-axis Automated Rotational Therapy (SMART) utilizing GyroStim device, Physical therapy and speech therapy/cognitive rehabilitation therapy
Device · Other
Lead sponsor
Neuroscience Group
Other
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Appleton, Wisconsin