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Conditions: Gestational Diabetes
Interventions: 4000 IU vitamin D3; Drug
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Pancreatic Cancer, Pancreas Cancer, Cancer of the Pancreas
Interventions: 5-FU, Leucovorin, Liposomal Irinotecan, Paricalcitol, Serum and plasma blood samples, Tumor biopsy; Drug · Procedure
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Vitamin D Deficiency
Interventions: Cholecalciferol; Drug
Lead sponsor: Parkview Medical Center; Other
Eligibility: 18 Years to 75 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Pueblo, Colorado

Conditions: Clonal Cytopenia of Undetermined Significance, High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements, Recurrent Diffuse Large B-Cell Lymphoma, Recurrent Hodgkin Lymphoma, Recurrent Lymphoma, Refractory Diffuse Large B-Cell Lymphoma, Refractory Lymphoma, Chronic Myelomonocytic Leukemia
Interventions: Ascorbic Acid, Carboplatin, Cisplatin, Cytarabine, Dexamethasone, Etoposide, Gemcitabine Hydrochloride, Ifosfamide, Laboratory Biomarker Analysis, Oxaliplatin, Placebo Administration, Questionnaire Administration, Rituximab, Decitabine, Biospecimen Collection, Core Biopsy, Bone Marrow Aspiration, Bone Marrow Biopsy, Echocardiography, Positron Emission Tomography, Magnetic Resonance Imaging, Central Venous Cannula Insertion, Portacath Placement, Computed Tomography; Dietary Supplement · Drug · Other + 2 more
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2033
U.S. locations: 4
States / cities: Mankato, Minnesota • Rochester, Minnesota • Eau Claire, Wisconsin + 1 more

Conditions: Morbid Obesity, Vitamin D Deficiency
Interventions: vitamin D3 (Replesta), vitamin D; Dietary Supplement
Lead sponsor: Texas Tech University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Lubbock, Texas

Conditions: Breast Cancer
Interventions: High Dose Vitamin D, Placebo, Standard Dose Vitamin D3, Letrozole 2.5mg; Dietary Supplement · Drug
Lead sponsor: Qamar Khan; Other
Eligibility: 18 Years and older · Female only
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 2
States / cities: Westwood, Kansas • Wichita, Kansas

Conditions: Death, Myocardial Infarction, Cerebral Vascular Accident, Heart Failure Hospitalization
Interventions: Vitamin D3; Biological
Lead sponsor: Intermountain Health Care, Inc.; Other
Eligibility: 18 Years and older
Enrollment: 634 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2025
U.S. locations: 1
States / cities: Murray, Utah

Conditions: Colon Cancer, Rectal Cancer
Interventions: cholecalciferol; Dietary Supplement
Lead sponsor: Legacy Health System; Other
Eligibility: 18 Years to 99 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 3
States / cities: Gresham, Oregon • Portland, Oregon • Tualatin, Oregon

Conditions: Vitamin D Deficiency, Cystic Fibrosis
Interventions: High-Dose Vitamin D3, Stool Sample, Sputum Sample, Sham Comparator, Blood draw; Dietary Supplement · Other · Procedure
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Chronic Kidney Disease, Hyperparathyroidism, Hyperparathyroidism, Secondary, Kidney Disease, Secondary Hyperparathyroidism
Interventions: cinacalcet capsule, placebo, Standard of Care; Drug
Lead sponsor: Amgen; Industry
Eligibility: 6 Years to 17 Years
Enrollment: 43 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2011
U.S. locations: 18
States / cities: Birmingham, Alabama • Los Angeles, California • San Francisco, California + 14 more

Conditions: Systemic Lupus Erythematosus
Interventions: Vitamin D3 6000 IU, Vitamin D3 400 IU; Drug
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 5 Years to 20 Years
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 13
States / cities: Los Angeles, California • Palo Alto, California • San Francisco, California + 9 more

Conditions: Metastatic Colorectal Cancer
Interventions: FOLFOX + bevacizumab, Vitamin D; Drug · Dietary Supplement
Lead sponsor: Dana-Farber Cancer Institute; Other
Eligibility: 18 Years and older
Enrollment: 139 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2019
U.S. locations: 18
States / cities: Boise, Idaho • Fruitland, Idaho • Meridian, Idaho + 13 more

Conditions: Sickle Cell Disease, Vitamin D Deficiency, Acute Chest Syndrome, Asthma, Respiratory Infections
Interventions: Experimental: Vitamin D3 100,000 IU, Active Comparator: Vitamin D3 12,000 IU; Drug
Lead sponsor: Gary M Brittenham, MD; Other
Eligibility: 3 Years to 20 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: New York, New York

Conditions: Colorectal Adenocarcinoma
Interventions: Bevacizumab, Oxaliplatin, Leucovorin Calcium, Fluorouracil, Irinotecan Hydrochloride, Irinotecan, Cholecalciferol, Quality-of-Life Assessment, Questionnaire Administration; Drug · Dietary Supplement · Other
Lead sponsor: Alliance for Clinical Trials in Oncology; Other
Eligibility: 18 Years and older
Enrollment: 455 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2026
U.S. locations: 1027
States / cities: Birmingham, Alabama • Anchorage, Alaska • Fairbanks, Alaska + 676 more

Conditions: Vitamin D Deficiency
Interventions: Vitamin D3; Drug
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 13 Years to 20 Years
Enrollment: 183 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Metastatic Cancer, Prostate Cancer
Interventions: zoledronic acid, placebo, androgen deprivation therapy, GnRH agonist, Calcium supplement, Vitamin D; Drug · Other · Dietary Supplement
Lead sponsor: Alliance for Clinical Trials in Oncology; Other
Eligibility: 18 Years and older · Male only
Enrollment: 645 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2014
U.S. locations: 238
States / cities: Mobile, Alabama • Fort Smith, Arkansas • Little Rock, Arkansas + 159 more

Conditions: Short Segment Barrett's Esophagus, Long Segment Barrett's Esophagus
Interventions: Omeprazole, Vitamin D3, upper endoscopy, Metformin; Drug · Procedure
Lead sponsor: Case Comprehensive Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2016
U.S. locations: 3
States / cities: Beachwood, Ohio • Cleveland, Ohio

Conditions: Obesity, Insulin Resistance, Vitamin D Deficiency
Interventions: Vitamin D3; Drug
Lead sponsor: Perrin C White, MD; Other
Eligibility: 6 Years to 17 Years
Enrollment: 109 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Osteoarthritis, Vitamin D Deficiency
Interventions: Vitamin D3; Drug
Lead sponsor: University of Miami; Other
Eligibility: 18 Years to 96 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Bone Metabolism Biomarkers, Bone Mineral Density, Physical Fitness
Interventions: Vitamin D3, Physical Activity; Drug · Behavioral
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years to 99 Years · Female only
Enrollment: 191 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2026
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Vitamin D Deficiency, Stem Cell Transplant Complications, Pediatric Cancer, Blood Disorder, Pediatric Acute Myeloid Leukemia, Pediatric Acute Lymphoid Leukemia, Myelodysplastic Syndromes, Sickle Cell Anemia in Children, Aplastic Anemia, Thalassemia in Children
Interventions: Vitamin D3, Standard Vitamin D3 Supplementation; Dietary Supplement
Lead sponsor: Phoenix Children's Hospital; Other
Eligibility: 1 Year to 25 Years
Enrollment: 49 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Hot Flushes, Menopause, Premature, Obesity, Vitamin D Deficiency
Interventions: Vitamin D, Placebo; Dietary Supplement · Other
Lead sponsor: Kaiser Permanente; Other
Eligibility: 40 Years to 60 Years · Female only
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Respiratory Infection
Interventions: High Dose Vitamin D, Standard Dose Vitamin D, Placebo, Usual Care; Drug · Dietary Supplement
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 60 Years and older
Enrollment: 107 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2016
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Kidney Transplantation, Vitamin D Deficiency
Interventions: Standard vitamin D3 treatment, High dose vitamin D3 treatment; Dietary Supplement
Lead sponsor: University of Nebraska; Other
Eligibility: 19 Years and older
Enrollment: 116 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2023
U.S. locations: 1
States / cities: Omaha, Nebraska

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High Dose Cholecalciferol to Reduce the Incidence of Gestational Diabetes in High Risk Pregnant Women

Liposomal Irinotecan Plus 5-FU / LV Combined With Paricalcitol in Patients With Advanced Pancreatic Cancer Progressed on Gemcitabine-based Therapy

Treatment of Vitamin D Deficiency With Large Bolus Cholecalciferol

Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia

Effect of a Monthly High Dose of Vitamin D3 on Bariatric Surgery Patients

Vitamin D3 for Aromatase Inhibitor Induced Arthralgias

A Trial Evaluating Vitamin D Normalization on Major Adverse Cardiovascular-Related Events Among Myocardial Infarction Patients

Effectiveness of High Dose Vitamin D Supplementation in Stage III Colorectal Cancer

Vitamin D and Microbiota in Cystic Fibrosis

Pediatric Chronic Kidney Disease Safety and Efficacy

Vitamin D3 Treatment in Pediatric Systemic Lupus Erythematosus

Study of Vitamin D in Untreated Metastatic Colorectal Cancer

Vitamin D for Sickle-cell Respiratory Complications

Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer

Treatment Study of Vitamin D Deficiency in Adolescents

Zoledronate in Preventing Skeletal (Bone)-Related Events in Men Who Are Receiving Androgen Deprivation Therapy For Prostate Cancer and Bone Metastases

Vitamin D Supplementation on 15-Prostaglandin Dehydrogenase Expression in Barrett's Esophagus

Correction of Vitamin D Levels and Its Effect on Insulin Resistance and Weight Gain in Obese Youth

Preoperative Correction of Vitamin D Deficiency in Total Joint Arthroplasty (TJA)

Vitamin D and Physical Activity on Bone Health

A Randomized Phase IV Control Trial of Single High Dose Oral Vitamin D3 in Pediatric Patients Undergoing HSCT

The Role of Vitamin D in Menopause: Relationship to Menopausal Symptoms in Body Composition

Vitamin D Supplementation and Acute Respiratory Infection in Older Long-Term Care Residents

Vitamin D Replacement After Kidney Transplant