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ClinicalTrials.gov public records Last synced Sep 19, 2026, 11:44 AM EDT

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Showing 1–24 of 433 matching trials from the live ClinicalTrials.gov search.
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Conditions
Aortic Stenosis Treated With TAVI, Aortic Diseases
Interventions
F2 Filter and Delivery System, Transcatheter Aortic Valve Replacement (TAVR)
Device · Procedure
Lead sponsor
EnCompass Technologies, Inc.
Industry
Eligibility
50 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
8
States / cities
Naples, Florida • Indianappolis, Indiana • Detroit, Michigan + 5 more
Terminated Not applicable Interventional Results available

REGENETEN™ Bioinductive Implant System in Full-thickness Tears

NCT04450342
Conditions
Rotator Cuff Injuries
Interventions
Arthroscopic rotator cuff repair with REGENETEN™ Bioinductive Implant augmentation, Arthroscopic rotator cuff repair, Arthroscopic rotator cuff repair for revision surgery
Device · Procedure
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
40 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
8
States / cities
Rome, Georgia • Chicago, Illinois • Baltimore, Maryland + 5 more
Conditions
Chronic Pain
Interventions
Office-based procedure indicated for chronic pain with music, Office-based procedure indicated for chronic pain without music
Procedure
Lead sponsor
Lake Erie College of Osteopathic Medicine
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Wesley Chapel, Florida • Zephyrhills, Florida
Conditions
Glioblastoma
Interventions
GammaTile®, External Beam Radiation Therapy, Temozolomide
Device · Radiation · Drug
Lead sponsor
GT Medical Technologies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
766 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
9
States / cities
Scottsdale, Arizona • Atlanta, Georgia • Baltimore, Maryland + 6 more
Conditions
Degenerative Disc Disease(DDD)
Interventions
Circumferential Cervical Fusion (CCF), Anterior Cervical Discectomy and Fusion
Device · Procedure
Lead sponsor
Providence Medical Technology, Inc.
Industry
Eligibility
18 Years and older
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Paducah, Kentucky
Conditions
Contraception Behavior
Interventions
LARC education and training
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 25 Years · Female only
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
San Francisco, California
Conditions
Arteriovenous Graft
Interventions
SRM003, Participating Site's standard practice
Biological · Other
Lead sponsor
Shire
Industry
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
46
States / cities
Phoenix, Arizona • Tucson, Arizona • Fresno, California + 40 more
Conditions
Jaw, Edentulous
Interventions
Overdenture treatment
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2023
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Hearing Loss
Interventions
Electrical stimulator
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
New York, New York
Conditions
Breast Carcinoma, Breast Cancer
Interventions
Measurement of Body Composition, Chart Review
Procedure · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
San Francisco, California
Conditions
Prostate Cancer
Interventions
RapidStrand seeds for use with 18g needle, ThinStrand
Device
Lead sponsor
Prostate Cancer Foundation of Chicago
Other
Eligibility
40 Years and older · Male only
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2010
U.S. locations
1
States / cities
Westmont, Illinois
Completed Not applicable Interventional Results available

Does Implant Design Improve Postoperative Flexion?

NCT00380861
Conditions
Non-inflammatory Arthritis
Interventions
Total knee replacement using the PFC Sigma RPF knee implant., Total knee replacement using the PFC Sigma RP knee implant
Device
Lead sponsor
DePuy Orthopaedics
Industry
Eligibility
40 Years to 70 Years
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
4
States / cities
Denver, Colorado • Jacksonville, Florida • Iowa City, Iowa + 1 more
Conditions
Recurrent Glioblastoma, IDH-Wildtype
Interventions
Cerebraca wafer, Temozolomide (for relapsed malignant glioma)
Drug
Lead sponsor
Everfront Biotech Co., Ltd.
Industry
Eligibility
18 Years and older
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
Providence, Rhode Island
Conditions
Periprosthetic Joint Infection
Interventions
Single Debridement, Antibiotics and Implant Retention, Planned Double Debridement, Antibiotics and Implant Retention
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
490 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2032
U.S. locations
2
States / cities
Jacksonville, Florida • Rochester, Minnesota
Conditions
Osteoporosis, Arthroplasty Complications, Fragility Fracture
Interventions
Surgeon-Initiated Bone Health Referral Pathway
Combination Product
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years and older
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Columbia, Maryland
Conditions
Missing Tooth
Interventions
Platform-matched dental implant, Platform-switched dental implant
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 100 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Louisville, Kentucky
Completed Not applicable Interventional Accepts healthy volunteers

Procedures for Improving the Mucosa Around Implants

NCT01944267
Conditions
Keratinized Mucosa, Dental Implants
Interventions
Apically positioned flap, Free Gingival Graft, apically positioned flap with Mucograft
Procedure
Lead sponsor
Tufts University
Other
Eligibility
18 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Withdrawn Early Phase 1 Interventional Accepts healthy volunteers

Pre-Emptive Analgesia in Dental Implant Surgery

NCT03243032
Conditions
Pain, Postoperative
Interventions
Ibuprofen 600 mg, Local anesthetic Group 1, Placebo oral capsule, Local anesthetic Control
Drug
Lead sponsor
Satheesh Elangovan
Other
Eligibility
18 Years to 64 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Coronary Artery Disease
Interventions
VEST, Coronary artery bypass vein grafts
Device · Procedure
Lead sponsor
Vascular Graft Solutions Ltd.
Industry
Eligibility
21 Years and older
Enrollment
224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
14
States / cities
Los Angeles, California • Fort Wayne, Indiana • Baltimore, Maryland + 9 more
Conditions
Epilepsy
Interventions
fMRI, Neuropsychological Testing, Additional electrode implantation, Electrical brain stimulation
Other
Lead sponsor
Northwell Health
Other
Eligibility
5 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2029
U.S. locations
1
States / cities
Great Neck, New York
Conditions
Breast Cancer
Interventions
Tamoxifen, Lumpectomy, brachytherapy
Drug · Procedure · Radiation
Lead sponsor
Masonic Cancer Center, University of Minnesota
Other
Eligibility
18 Years and older · Female only
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2013
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Missing Teeth
Interventions
dental implant placement and immediate provisionalization
Device
Lead sponsor
Harvard Medical School (HMS and HSDM)
Other
Eligibility
20 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Results available

LINX Reflux Management System Clinical Study Protocol

NCT00776997
Conditions
Gastroesophageal Reflux
Interventions
Magnetic Sphincter Augmentation
Device
Lead sponsor
Torax Medical Incorporated
Industry
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
13
States / cities
Los Angeles, California • San Diego, California • Jacksonville, Florida + 10 more
Completed Not applicable Interventional Accepts healthy volunteers

Comparing Implant Stability Using Two Accepted Techniques for Implant Sites

NCT02096978
Conditions
Implant
Interventions
Preparing the osteotomy to accept a standard implant device
Procedure
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 65 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Newark, New Jersey