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Showing 1–24 of 166 matching trials from the live ClinicalTrials.gov search.
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Completed Phase 4 Interventional Results available

Loss of Resistance, w/wo Stimulation, For Epidural Placement

NCT03087604
View directory record Official record
Conditions
Anesthesia
Interventions
Thoracic epidural block, Electrical Nerve stimulation, Solution For Thoracic epidural block
Procedure · Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 16, 2020 · Synced Sep 5, 2026, 3:23 PM EDT
Recruiting Phase 1Phase 2 Interventional

Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Granulomatous Disease (CGD) With an Alemtuzumab, Busulfan and TBI-based Conditioning Regimen Combined With Cytokine (IL-6, +/- IFN-gamma) Antagonists

NCT05463133
View directory record Official record
Conditions
Chronic Granulomatous Disease
Interventions
Sirolimus, Cyclophosphamide, Alemtuzumab, Busulfan, Pheripheral blood stem cells, Emapalumab-Izsg, Tociluzumab, Total Body Irradiation
Drug · Biological
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
4 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2032
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Sep 5, 2026, 3:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Radiofrequency and Hybrid Fractional Laser for Vaginal Rejuvenation

NCT03316950
View directory record Official record
Conditions
Vaginal Atrophy
Interventions
IntraGen RF, DiVA, Placebo (DIVA/IntraGen combined)
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
40 Years to 65 Years · Female only
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 3, 2023 · Synced Sep 5, 2026, 3:23 PM EDT
Completed Phase 2 Interventional Results available

eIMPACT-DM Pilot Trial: Depression Treatment to Reduce Diabetes Risk

NCT04437485
View directory record Official record
Conditions
Depression, Major Depressive Disorder, Dysthymic Disorder, Depressive Symptoms, Type 2 Diabetes, PreDiabetes, Insulin Resistance
Interventions
Good Days Ahead (GDA), Problem Solving Treatment in Primary Care (PST-PC), Antidepressant Medications, Active Control
Behavioral · Drug · Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 1, 2023 · Synced Sep 5, 2026, 3:23 PM EDT
Completed Phase 2 Interventional Results available

Galantamine to Enhance Cognitive Behavioral Therapy for Cocaine Abuse

NCT00809835
View directory record Official record
Conditions
Cocaine Dependence
Interventions
Galantamine, Computer Assisted Cognitive Behavioral Therapy (CBT)
Drug · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 50 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2015
U.S. locations
2
States / cities
Bridgeport, Connecticut • Stratford, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 29, 2019 · Synced Sep 5, 2026, 3:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Fluid Volume During Fluid Shifts

NCT03447574
View directory record Official record
Conditions
Development of Non-invasive Protocol
Interventions
ethanol dilution
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
3
States / cities
Scottsdale, Arizona • Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 7, 2022 · Synced Sep 5, 2026, 3:23 PM EDT
Active, not recruiting Not applicable Interventional

Feasibility of the 5-Step Method in the U.S.

NCT06565429
View directory record Official record
Conditions
Family Members, Relatives, Substance-Related Disorders, Alcohol-Related Disorders, Coping Skills, Stress, Psychological, Stress Physiology
Interventions
5-Step Method Intervention
Behavioral
Lead sponsor
Villanova University
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Winchester, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Sep 5, 2026, 3:23 PM EDT
Not listed Phase 4 Interventional

Evaluation of Liposomal Bupivacaine Compared to Usual Care and Its Effects on Pain for Cardiac Surgery

NCT04065919
View directory record Official record
Conditions
Cardiothoracic Surgery
Interventions
Liposomal bupivacaine, 0.25% Bupivacaine with epinephrine
Drug
Lead sponsor
Florida Heart and Lung Institute
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 5, 2020 · Synced Sep 5, 2026, 3:23 PM EDT
Withdrawn Not applicable Interventional

Evaluation of Fracture Fixation With Energy and Cement in Tumors of the Spine

NCT00594321
View directory record Official record
Conditions
Spinal Fractures
Interventions
SPACE CpsXL Bone Cement and SPACE 360 Delivery System, standard vertebroplasty
Device
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Sep 2, 2012 · Synced Sep 5, 2026, 3:23 PM EDT
Completed Not applicable Interventional

Gravity- Versus Suction-driven Large Volume Thoracentesis

NCT03591952
View directory record Official record
Conditions
Pleural Effusion
Interventions
Suction-Driven Thoracentesis, Gravity-Driven Thoracentesis
Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 13, 2022 · Synced Sep 5, 2026, 3:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Childcare Outdoor Learning Environments as Active Food Systems

NCT04864574
View directory record Official record
Conditions
Pediatric Obesity, Sedentary Behavior
Interventions
Garden installation
Other
Lead sponsor
North Carolina State University
Other
Eligibility
42 Months to 6 Years
Enrollment
286 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
15
States / cities
Cary, North Carolina • Fuquay-Varina, North Carolina • Knightdale, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 28, 2021 · Synced Sep 5, 2026, 3:23 PM EDT
Completed Phase 1Phase 2 Interventional

Sterile Amniotic Fluid Filtrate Epidural Injection.

NCT04537026
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
Amniotic Fluid Allograft, Dexamethasone sodium phosphate
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Sep 23, 2025 · Synced Sep 5, 2026, 3:23 PM EDT
Recruiting Not applicable Interventional

Virtual Reality During Lumbar Punctures in Acute Lymphoblastic Leukemia

NCT06722638
View directory record Official record
Conditions
Acute Lymphoblastic Leukemia, Pediatric
Interventions
Use of Virtual Reality Headset
Other
Lead sponsor
Children's National Research Institute
Other
Eligibility
7 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Dec 8, 2024 · Synced Sep 5, 2026, 3:23 PM EDT
Withdrawn Phase 2 Interventional Accepts healthy volunteers

Novel Collagen Scaffold vs Conventional Scaffold in Regeneration of Human Dental Pulp Tissue

NCT03613090
View directory record Official record
Conditions
Root Canal Therapy
Interventions
Collagen-hydroxyapatite scaffold (Syn-Oss), Collagen Scaffold (Colla-Plug)
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
12 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 22, 2019 · Synced Sep 5, 2026, 3:23 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

A Comparison Trial Between PCA and Epidural Analgesia for Pectus Excavatum Repair

NCT02056301
View directory record Official record
Conditions
Pectus Excavatum
Interventions
Hydromorphone, Morphine
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
8 Years to 18 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 10, 2020 · Synced Sep 5, 2026, 3:23 PM EDT
Recruiting Phase 4 Interventional

Novel Extended-Release Bupivacaine Polymer for Sustained Pain Relief Following Total Knee Arthroplasty

NCT07775248
View directory record Official record
Conditions
Osteoarthritis (OA) of the Knee
Interventions
Periarticular Injection, Adductor Canal Block, Bupivacaine-Meloxicam
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Grosse Pointe Farms, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Sep 5, 2026, 3:23 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Lumoptik BRIGHTPOINT Reflectometer Device for Lumbar Epidural Placement

NCT06020508
View directory record Official record
Conditions
Lumbar Spine Surgery
Interventions
Group 1 - Lumoptik BrightPoint Epidural Device
Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 99 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 9, 2026 · Synced Sep 5, 2026, 3:23 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Comparative Analysis of Spinal Anesthesia Versus General Anesthesia for vNOTES

NCT05688943
View directory record Official record
Conditions
Anesthesia, Tubal Ligation
Interventions
Spinal Anesthesia, General Anesthesia
Procedure
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
21 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Sep 5, 2026, 3:23 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Pleural Space Saline Irrigation in Addition to Standard Intrapleural Thrombolytic Therapy in Empyema/Complicated Parapneumonic Effusion

NCT06434324
View directory record Official record
Conditions
Pleural Infection
Interventions
Saline Irrigation
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Sep 5, 2026, 3:23 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluation of a Powered Ankle Prosthesis Capable of Bidirectional Control Via Neural Recording and Cutaneous Stimulation in Free-Space and Walking Tasks

NCT07645729
View directory record Official record
Conditions
Amputation
Interventions
Powered Prosthesis, Prescribed Prosthesis
Device
Lead sponsor
Massachusetts Institute of Technology
Other
Eligibility
18 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2031
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Sep 5, 2026, 3:23 PM EDT
Recruiting Not applicable Interventional

BELIEVE Trial: Bulking vErsus sLing for Treating Stress Urinary IncontinEnce at the Time of Vaginal prolapsE Repair (BELIEVE)

NCT06754046
View directory record Official record
Conditions
Stress Urinary Incontinence, Vaginal Prolapse
Interventions
RP-MUS, PAHG
Device · Procedure
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
476 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 31, 2026 · Synced Sep 5, 2026, 3:23 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effects of Analgesic Techniques on Duration of Labor for Induction Patients

NCT01982851
View directory record Official record
Conditions
Effects of; Anesthesia, in Labor and Delivery, Pregnancy, Prolonged First Stage of Labor
Interventions
Epidural de novo, CSE
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 10, 2014 · Synced Sep 5, 2026, 3:23 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Does a Brief Intervention Decrease Patient Drop Out Rates?

NCT04803045
View directory record Official record
Conditions
Infertility
Interventions
Follow up email
Other
Lead sponsor
Boston IVF
Other
Eligibility
Female only
Enrollment
647 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Waltham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 21, 2021 · Synced Sep 5, 2026, 3:23 PM EDT
Withdrawn Phase 2 Interventional

OsciPulse D-dimer Efficacy Trial

NCT05389488
View directory record Official record
Conditions
Venous Thromboses, Ischemic Stroke
Interventions
OsciPulse system, Flowtron ACS900
Device
Lead sponsor
OsciFlex LLC
Industry
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 6, 2023 · Synced Sep 5, 2026, 3:23 PM EDT