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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Standard Wound Closure Clear all
Suspended Not applicable Interventional

Aesthetic Outcome of Tie-over Bolster Application in Surgical Wounds

NCT05758168
View directory record Official record
Conditions
Scarring
Interventions
Addition of Tie-Over Bolster Dressing
Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Sep 24, 2026, 2:09 PM EDT
Completed Not applicable Interventional

Aesthetic Outcome of Layered Closure vs. Layered Closure Followed by 2-Octyl Cyanoacrylate

NCT05449457
View directory record Official record
Conditions
Scarring
Interventions
2-Octyl cyanoacrylate
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 13, 2024 · Synced Sep 24, 2026, 2:09 PM EDT
Completed Phase 4 Interventional Results available

Efficacy of Peri-Incisional Multimodal Drug Injection Following Operative Management of Femur Fractures

NCT02793947
View directory record Official record
Conditions
Pain, Postoperative, Femur Fracture
Interventions
Ropivacaine, Epinephrine, Morphine, 0.9% sodium chloride solution
Drug
Lead sponsor
University of Iowa
Other
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Apr 4, 2018 · Synced Sep 24, 2026, 2:09 PM EDT
Completed Phase 2 Interventional Results available

Teduglutide for Enterocutaneous Fistula (ECF)

NCT02889393
View directory record Official record
Conditions
Postoperative Fistula
Interventions
Teduglutide, Standard of Care
Drug · Other
Lead sponsor
Daniel Dante Yeh
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Oct 5, 2021 · Synced Sep 24, 2026, 2:09 PM EDT
Recruiting Not applicable Interventional

Outcomes of Running Locking Suture vs Standard Running Suture in Surgical Wounds

NCT06288009
View directory record Official record
Conditions
Scarring
Interventions
Running locking suture, Standard running suture
Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Sep 24, 2026, 2:09 PM EDT
Recruiting Not applicable Interventional

Miro3D Wound Matrix for Treatment of Diabetic Foot Ulcers

NCT07632001
View directory record Official record
Conditions
Diabetic Foot Ulcers (DFUs), Diabetic Foot, Chronic Wounds
Interventions
Miro3D Wound Matrix, Standard of Care
Device · Other
Lead sponsor
Reprise Biomedical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
14
States / cities
Phoenix, Arizona • Coconut Creek, Florida • Coral Gables, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Sep 24, 2026, 2:09 PM EDT
Terminated Not applicable Interventional Results available

Secondary Versus Tertiary Wound Closure in High Risk Gynecologic Abdominal Surgical Incisions

NCT03861065
View directory record Official record
Conditions
Surgical Incision
Interventions
Tertiary Wound Closure, Historical Wound Closure
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Sep 24, 2026, 2:09 PM EDT
Completed Not applicable Interventional

Clinical Study Evaluating Symphony™ Versus Standard of Care in the Treatment of Non-Healing Diabetic Foot Ulcers

NCT06035536
View directory record Official record
Conditions
Diabetic Foot, Diabetic Foot Ulcer, Foot Ulcer, Chronic Foot Ulcer
Interventions
Symphony™ plus Off-loading, Wound Dressing comprising of calcium alginate Fibracol
Device
Lead sponsor
Aroa Biosurgery Limited
Industry
Eligibility
18 Years and older
Enrollment
143 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
11
States / cities
Los Angeles, California • San Francisco, California • Miami, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Sep 24, 2026, 2:09 PM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

The Use of Steri3X for Prevention of Post-operative Wound Infections in Cesarean Sections

NCT05392400
View directory record Official record
Conditions
Surgical Site Infection, Cesarean Section; Complications, Wound, Infection (Following Delivery), Postpartum Complication
Interventions
Steri3X, Control
Device · Other
Lead sponsor
University of Tennessee
Other
Eligibility
16 Years and older · Female only
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 12, 2023 · Synced Sep 24, 2026, 2:09 PM EDT
Withdrawn Not applicable Interventional

Negative Pressure Wound Therapy vs Standard Care Dressing

NCT03566641
View directory record Official record
Conditions
Negative-Pressure Wound Therapy
Interventions
Negative pressure wound therapy, standard care dressing
Device · Other
Lead sponsor
University of Toledo Health Science Campus
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated May 20, 2024 · Synced Sep 24, 2026, 2:09 PM EDT
Not listed Not applicable Interventional

Optimal Method of Fascial Closure in High Risk Patients Undergoing Laparotomy

NCT02145052
View directory record Official record
Conditions
Fascial Closure
Interventions
Continuous suture, Interrupted suture
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
388 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 28, 2016 · Synced Sep 24, 2026, 2:09 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Preventing Adverse Incisional Outcomes at Cesarean Multicenter Trial

NCT03009110
View directory record Official record
Conditions
Surgical Wound Infection, Cesarean Section
Interventions
Prophylactic NPWT, Standard Dressing
Device
Lead sponsor
Indiana University
Other
Eligibility
16 Years and older · Female only
Enrollment
1,624 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
6
States / cities
Birmingham, Alabama • Indianapolis, Indiana • New Orleans, Louisiana + 1 more
Source: ClinicalTrials.gov public record
Updated May 31, 2023 · Synced Sep 24, 2026, 2:09 PM EDT
Recruiting Phase 2 Interventional

The Effects of Tranexamic Acid on Joint Inflammation and Cartilage Health in Anterior Cruciate Ligament Injured Patients

NCT03552705
View directory record Official record
Conditions
Anterior Cruciate Ligament Reconstruction
Interventions
Tranexamic Acid, Placebos
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 30 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 24, 2026, 2:09 PM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

Vacuum Assisted Closure for Cesarean Section

NCT02390401
View directory record Official record
Conditions
Surgical Wound Infection
Interventions
Vacuum-assisted closure, Standard sterile dressing
Device
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
166 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
4
States / cities
Lebanon, New Hampshire • Nashua, New Hampshire
Source: ClinicalTrials.gov public record
Updated May 21, 2018 · Synced Sep 24, 2026, 2:09 PM EDT
Recruiting Not applicable Interventional

Study of Miro3D Wound Matrix for Healing Wounds and Ulcers in Outpatient Care

NCT06939673
View directory record Official record
Conditions
Diabetic Foot Ulcers (DFUs), Venous Leg Ulcers (VLUs), Pressure Ulcers, Surgical Wound Dehiscence (SWD), Chronic Wounds, Undermined and Tunneling Wounds
Interventions
Acellular Porcine-Derived Wound Matrix
Device
Lead sponsor
Reprise Biomedical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Coconut Creek, Florida • Tamarac, Florida
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Sep 24, 2026, 2:09 PM EDT
Completed Phase 2 Interventional Results available

Efficacy and Safety of a Collagen Bupivacaine Implant in Women Following Abdominal Hysterectomy

NCT00624910
View directory record Official record
Conditions
Postoperative Pain
Interventions
Bupivacaine Collagen Sponge (CollaRx®), placebo
Drug
Lead sponsor
Innocoll
Industry
Eligibility
18 Years to 75 Years · Female only
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 22, 2021 · Synced Sep 24, 2026, 2:09 PM EDT
Completed Phase 3 Interventional Results available

Safety and Efficacy of an Antibiotic Implant in Cardiac Surgical Subjects at Higher Risk for Sternal Wound Infection

NCT00600483
View directory record Official record
Conditions
Cardiac Surgery, Sternal Wound Infection
Interventions
gentamicin-collagen sponge dipped in saline
Drug
Lead sponsor
Innocoll
Industry
Eligibility
18 Years and older
Enrollment
1,502 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
43
States / cities
Birmingham, Alabama • Florence, Alabama • Pasadena, California + 39 more
Source: ClinicalTrials.gov public record
Updated May 4, 2022 · Synced Sep 24, 2026, 2:09 PM EDT
Terminated Not applicable Interventional Results available

Use of Negative Pressure Wound Therapy in Morbidly Obese Women After Cesarean Delivery

NCT03269968
View directory record Official record
Conditions
Obesity, Morbid, Wound Infection, Wound Complication
Interventions
Negative pressure wound therapy (PREVENA Incision Management Therapy System), Standard dressing
Device
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 18, 2020 · Synced Sep 24, 2026, 2:09 PM EDT
Recruiting Not applicable Interventional

Pelashield™ PainGuard™ vs Restrata® in HS Surgery

NCT07316192
View directory record Official record
Conditions
Hidradenitis Suppurativa (HS)
Interventions
Pelashield Painguard
Device
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 24, 2026, 2:09 PM EDT
Terminated Not applicable Interventional Results available

Prevention of Wound Complications After Cesarean Delivery in Obese Women Utilizing Negative Pressure Wound Therapy

NCT00654641
View directory record Official record
Conditions
Surgical Wound Dehiscence, Wound Infection
Interventions
Negative pressure wound closure, Standard wound closure
Procedure
Lead sponsor
West Virginia University
Other
Eligibility
18 Years and older · Female only
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
2
States / cities
Charleston, West Virginia • Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Jan 29, 2013 · Synced Sep 24, 2026, 2:09 PM EDT
Not listed Not applicable Interventional

Comparison of microMend® Devices to Sutures in Closing Lacerations in Children

NCT04557761
View directory record Official record
Conditions
Laceration, Skin Wound, Wound Heal
Interventions
microMend®, Closure with Sutures
Device
Lead sponsor
Children's Hospital of Orange County
Other
Eligibility
7 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Mar 27, 2022 · Synced Sep 24, 2026, 2:09 PM EDT
Withdrawn Phase 3 Interventional

Bone Healing Accelerant Versus Standard of Care for Open Tibia Fractures

NCT03826784
View directory record Official record
Conditions
Tibial Fractures
Interventions
BHA
Combination Product
Lead sponsor
Carmell Therapeutics Corporation
Industry
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 22, 2020 · Synced Sep 24, 2026, 2:09 PM EDT
Enrolling by invitation Not applicable Interventional

Undermining Apices in Surgical Wounds

NCT05758181
View directory record Official record
Conditions
Scarring
Interventions
Apical Undermining
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Sep 24, 2026, 2:09 PM EDT
Completed Not applicable Interventional

Next Science Wound Gel Efficacy in Chronic Wound Versus Standard of Care

NCT02138994
View directory record Official record
Conditions
Wound Chronic Draining
Interventions
Next Science Wound Gel, Triple Antibiotic Ointment Neosporin
Device · Drug
Lead sponsor
Next Science TM
Industry
Eligibility
18 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 27, 2017 · Synced Sep 24, 2026, 2:09 PM EDT