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ClinicalTrials.gov public records Last synced Nov 12, 2026, 9:39 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 35 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Standard abdominal breathing Clear all

Conditions: GERD
Interventions: Diaphragm Training; Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 192 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Pelvic Pain, Chronic Pain, Muscle Tightness
Interventions: Orthopedic Physical Therapy Intervention, Dry Needling; Procedure · Device
Lead sponsor: Texas Woman's University; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Lee's Summit, Missouri

Conditions: Stress (Psychology), Resilience, Psychological, Anxiety, Depressive Symptoms, Well-being, Sleep Quality
Interventions: Wearable ring with continuous biometric monitoring, AI health coaching application, Osteopathic manipulative treatment (OMT); Device · Behavioral · Other
Lead sponsor: Touro University, California; Other
Eligibility: 18 Years and older
Enrollment: 43 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Vallejo, California

Conditions: Anesthesia and Analgesia
Interventions: Diaphragmatic Breathing; Behavioral
Lead sponsor: University of Southern California; Other
Eligibility: 50 Years to 90 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Gastric Cancer, Lung Cancer
Interventions: respiration correlated CT scan; Procedure
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2018
U.S. locations: 1
States / cities: New York, New York

Conditions: Lung Cancer, Non-small Cell Lung Cancer
Interventions: PET/CT and BH PET/CT; Procedure
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: New York, New York

Conditions: Pelvic Floor Disorders
Interventions: Preoperative and Postoperative Pelvic Floor Physical Therapy (PFPT), No Pelvic Floor Physical Therapy (PFPT), Postoperative PFPT; Other
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older · Male only
Enrollment: 37 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Insomnia, Alcohol Use Disorder
Interventions: Cognitive Behavioral Therapy for Insomnia, Sleep Hygiene, Alcohol Use Disorder Treatment as Usual; Behavioral
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 18 Years and older
Enrollment: 67 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: GERD
Interventions: Diaphragmatic Breathing, Sham Comparator; Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Premature Infant, Work of Breathing, Oxygen Saturation
Interventions: Not listed
Lead sponsor: Christiana Care Health Services; Other
Eligibility: 4 Days to 6 Months
Enrollment: 29 participants
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Newark, Delaware

Conditions: Nightmares, Stress Disorders, Post-Traumatic, Actigraphy, Respiratory Sinus Arrhythmia, Veterans
Interventions: Exposure, Relaxation, and Rescripting Therapy, Sleep and Nightmare Management; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Alcohol Abuse
Interventions: Brief Motivational Intervention (BMI), Substance-Free Activity Session (SFAS), Relaxation Session; Behavioral
Lead sponsor: University of Memphis; Other
Eligibility: 18 Years to 27 Years
Enrollment: 393 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 2
States / cities: Columbia, Missouri • Memphis, Tennessee

Conditions: Obesity, Morbid, Ventilator-Induced Lung Injury, Respiratory Failure
Interventions: Esophageal balloon, Intervention Spontaneous Breathing Trial (SBT) and Extubation, Control Spontaneous Breathing Trial and Extubation, Intervention Weaning after Tracheostomy, Control Weaning after Tracheostomy; Device · Procedure
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years and older
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 2
States / cities: Chapel Hill, North Carolina • Greenville, North Carolina

Conditions: Mild Cognitive Impairment, Accidental Falls, Aging
Interventions: dual-task tai ji quan, standard tai ji quan, stretching; Behavioral
Lead sponsor: Oregon Research Institute; Other
Eligibility: 65 Years to 95 Years
Enrollment: 336 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Springfield, Oregon

Conditions: Autonomic Nervous System Disease, Concussive Injury, Mild Traumatic Brain Injury, Post Traumatic Stress Disorder, Persistent Post Concussion Syndrome
Interventions: HRV Coherence Ratio, NSI, Pittsburgh Sleep Quality Index (PSQI), Quantitative Sleep Measures, Patient Global Impression of Change (PGIC), Cognitive Performance/NIH Toolbox Cognitive Battery, Pain Interference/TBI-QoL Pain Interference Short-Form, Patient Health Questionnaire-9 (PHQ-9), PTSD Checklist for DSM-5 (PCL-5), HRV Biofeedback (HRV-B), Psychoeducational (Edu) Comparator Intervention; Other · Behavioral
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years and older
Enrollment: 148 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Anxiety Sensitivity
Interventions: Standard exposure, Enhanced exposure, Intensive exposure, Expressive writing; Behavioral
Lead sponsor: University of Wyoming; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Laramie, Wyoming

Conditions: Cardiovascular Disease
Interventions: Integrative Therapies Intervention; Behavioral
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2007
U.S. locations: 1
States / cities: New York, New York

Conditions: Laryngeal/Pharyngeal Reflux (LPR)
Interventions: Standard abdominal breathing, Resisted Exercise; Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 69 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Asthma, HIV, Adiposity
Interventions: Blood draw, Questionnaires, Spirometry, Methacholine challenge test, Quantitative CT scans, Urine pregnancy test, Adipose biopsy, Exhaled nitric oxide measurement; Procedure · Other · Radiation
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 80 Years
Enrollment: 102 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Surgery
Interventions: Esophageal pressure measurement guided ventilation; Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Respiratory Distress Syndrome, Adult, Ventilator-Induced Lung Injury, Neurocognitive Dysfunction, Quality of Life, Respiration Disorders
Interventions: Ventilation Inhomogeneity, Diaphragm Ultrasound, Respiratory Inductance Plethysmography, Spirometry, Functional Residual Capacity, MIP/MEP, 6 minute walk test, Neurocognitive Testing, Emotional Health Assessment, Health Related Quality of Life, Functional Status, Respiratory Status Questionnaire; Diagnostic Test
Lead sponsor: Children's Hospital Los Angeles; Other
Eligibility: 1 Month to 18 Years
Enrollment: 176 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2026
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Chronic Pelvic Pain
Interventions: Pain Neuroscience Education, Lumbopelvic and Hip Therapeutic Exercise, Extrapelvic Manual Therapy, Extrapelvic Dry Needling, Deep Paced Diaphragmatic Breathing Training, Chronic Pelvic Pain Education, Intravaginal and intrarectal pelvic floor physical therapy; Other
Lead sponsor: Baylor University; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 2
States / cities: San Antonio, Texas • Waco, Texas

Conditions: Dysfunctional Voiding, Urinary Dysfunction
Interventions: Diaphragmatic Breathing Exercises, Bladder Hygiene Education; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 59 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 2
States / cities: Durham, North Carolina • Raleigh, North Carolina

Conditions: Constipation, Constipation by Outlet Obstruction, Constipation-predominant Irritable Bowel Syndrome, Constipation - Functional
Interventions: Standard Physical Therapy Care, Aerobic and Inspiratory Muscle Training; Other
Lead sponsor: University of Miami; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Coral Gables, Florida

Search by objective public record fields.

Effectiveness of Diaphragmatic Breathing on Reflux Symptoms in Outpatients

The Effect of an Individualized Impairment-based, Orthopedic Physical Therapy Intervention (IOI), on Muscle Stiffness, Pelvic Floor Function, and Pain in Women With Chronic Pelvic Pain

High-Tech, High-Touch

Diaphragmatic Breathing Exercises in Total Knee Arthroplasty Patients

Evaluation of Respiratory Motion-Corrected Cone-Beam CT in Radiation Treatment of Thoracic and Abdominal Cancers

Breathing Synchronized PET/CT Scans for the Detection of Malignant Lung & Liver Lesions and Assessment of Tumor Glycolysis

Pelvic Floor Physical Therapy vs Standard Care in Transgender Women Undergoing Vaginoplasty for Gender Affirmation

CBT-I on Alcohol Treatment Outcomes Among Veterans

Understanding the Pathophysiology and Effects of Diaphragmatic Breathing in Upright Gastroesophageal Reflux

Work of Breathing and Kangaroo Mother Care

Understanding Trauma Nightmares Using In-Home Measurement

Improving Brief Alcohol Interventions With a Behavioral Economic Supplement

Providing Optimal PEEP During Mechanical Ventilation for Obese Patients Using Esophageal Balloon

A Study of Dual-task Exercise Training to Prevent Falls Among Older Adults With Mild Cognitive Impairment

Randomized Controlled Trial of Treatment to Optimize Heart Rate Variability for Persistent Post-Concussion Symptoms

Comparison of Methods for the Delivery of Interoceptive Exposure

Usefulness of Integrative Medicine Tools As Adjunctive Care for Women After Coronary Artery Bypass Grafting

Effectiveness of Two Diaphragmatic Strengthening Programs on Symptoms of LPR as Measured by the Reflux Symptom Index (RSI) and the Reflux Disease Questionnaire (RDQ)

Adiposity and Airway Inflammation in HIV-Associated Airway Disease

Esophageal Balloon Measurements to Better Characterize Thoraco-abdominal Interrelationship Mechanics.

Long Term Follow up of Children Enrolled in the REDvent Study

Conservative Care for Pelvic Pain (C2P2) in Women Service Members

At-Home Diaphragmatic Interventions for Voiding Abnormalities (DIVA)

The Impact of Aerobic Interval and Inspiratory Muscle Training On Patient Reported Outcome Scores In Individuals With Chronic Constipation