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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Standard abstinence Clear all
Completed Phase 4 Interventional Accepts healthy volunteers

Reinforcement-Based Treatment and Abstinence-Contingent Housing for Drug Abusers

NCT00685620
View directory record Official record
Conditions
Drug Abuse
Interventions
Reinforcement Based Treatment
Behavioral
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 65 Years
Enrollment
463 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2007
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 10, 2017 · Synced Sep 19, 2026, 9:33 PM EDT
Completed Not applicable Interventional Results available

Neural Mechanisms Associated With Risk of Smoking Relapse

NCT02837510
View directory record Official record
Conditions
Nicotine Addiction
Interventions
Standard smoking cessation counseling
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 4, 2025 · Synced Sep 19, 2026, 9:33 PM EDT
Completed Phase 1 Interventional

Reducing Drug Use and HIV Risk in Drug-dependent Adults Arrested for Prostitution

NCT01560221
View directory record Official record
Conditions
Substance-related Disorders, HIV Risk Behavior
Interventions
Therapeutic Workplace, Methadone, Buprenorphine
Behavioral · Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 65 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 10, 2014 · Synced Sep 19, 2026, 9:33 PM EDT
Completed Not applicable Interventional Results available

Interventions for Unemployed Hazardous Drinkers

NCT02559609
View directory record Official record
Conditions
Unemployment, Hazardous Drinking
Interventions
Contingency management for alcohol abstinence, Contingency management for completing job related activities, Job relelated activity contracting
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years to 65 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Middletown, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 22, 2024 · Synced Sep 19, 2026, 9:33 PM EDT
Completed Not applicable Interventional

Mobile Contingency Management for Smoking Cessation in Returning US Veterans

NCT02513069
View directory record Official record
Conditions
Smoking, Veterans
Interventions
Nicotine gum, mobile contingency management, Telephone counseling, Nicotine patch, Nicotine lozenge, Smart phone, Carbon monoxide monitor
Other · Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
291 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 20, 2020 · Synced Sep 19, 2026, 9:33 PM EDT
Completed Not applicable Interventional

Adaptive Interventions for Problem Drinkers

NCT02511808
View directory record Official record
Conditions
Alcohol-Related Disorders, Alcohol Use Disorders, Alcohol Drinking, Alcoholism, Alcohol Abuse
Interventions
Brief Advice, Motivational Interviewing, Behavioral Self-Control Training
Behavioral
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 75 Years
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Great Neck, New York
Source: ClinicalTrials.gov public record
Updated Sep 10, 2020 · Synced Sep 19, 2026, 9:33 PM EDT
Completed No phase listed Observational

The Pharmacokinetics of Oral Methadone in the Treatment of Neonatal Abstinence Syndrome

NCT01754324
View directory record Official record
Conditions
Neonatal Abstinence Syndrome
Interventions
Methadone
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Up to 1 Month
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
2
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 12, 2014 · Synced Sep 19, 2026, 9:33 PM EDT
Completed Not applicable Interventional

Buprenorphine and Substance Abuse Services for Prescription Opioid Dependence

NCT02496403
View directory record Official record
Conditions
Opiate Substitution Treatment
Interventions
Standard Medical Management (SMM)
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
239 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Sep 25, 2019 · Synced Sep 19, 2026, 9:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Lung and Breast Cancer Prevention by an Integrated Intervention of Maternal Smoking Cessation and Breastfeeding

NCT05123118
View directory record Official record
Conditions
Smoking, Cigarette, Breastfeeding
Interventions
Integrated intervention of smoking cessation and breastfeeding, Attention placebo control
Behavioral
Lead sponsor
Xiaozhong Wen
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Apr 16, 2025 · Synced Sep 19, 2026, 9:33 PM EDT
Withdrawn Phase 2 Interventional

Inpatient Buprenorphine Induction With Psilocybin for Opioid Use Disorder

NCT06005662
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
Psilocybin
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 22, 2026 · Synced Sep 19, 2026, 9:33 PM EDT
Active, not recruiting Not applicable Interventional

Enhancing Long-Term Smoking Abstinence Among Cervical Cancer Survivors (Project ACCESS)

NCT05645146
View directory record Official record
Conditions
Smoking Cessation, Cervical Cancer, High Grade Cervical Dysplasia
Interventions
Smoking Cessation treatment delivered by Tobacco Free Florida Quitline, Nicotine patch, Nicotine Lozenge, Motivation and Problem Solving (MAPS) intervention
Behavioral · Drug
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Sep 19, 2026, 9:33 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Automated Mobile Contingency Management for Smoking Cessation: A Pilot RCT (SCC PREVAILgo)

NCT03739437
View directory record Official record
Conditions
Smoking Cessation
Interventions
Mobile Contingency Management, Standard Care
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 100 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 3, 2023 · Synced Sep 19, 2026, 9:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Multimodal Neuroimaging of Stress and Reward Cues to Assess Alcoholism Risk and Relapse

NCT02616094
View directory record Official record
Conditions
Alcohol Dependence
Interventions
Multi-method Neuroendocrine and Neuroimaging Procedure Scan 1, Multi-method Neuroendocrine and Neuroimaging Procedure Scan 2
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years to 60 Years
Enrollment
224 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 17, 2023 · Synced Sep 19, 2026, 9:33 PM EDT
Completed Not applicable Interventional Results available

Contingency Management to Promote Smoking Abstinence in Cancer Patients

NCT04605458
View directory record Official record
Conditions
Smoking Cessation
Interventions
Contingency Management, Standard Care
Combination Product
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
282 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 19, 2026, 9:33 PM EDT
Completed Not applicable Interventional Results available

Optimizing Pregnancy and Treatment Interventions for Moms 2.0

NCT03833245
View directory record Official record
Conditions
Pregnancy, High Risk, Opioid-Related Disorders, Pregnancy Related
Interventions
Patient Navigation
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older · Female only
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 2, 2025 · Synced Sep 19, 2026, 9:33 PM EDT
Not yet recruiting Not applicable Interventional

Methamphetamine Use Disorder Support in Heart Failure Pilot Study

NCT07211724
View directory record Official record
Conditions
Heart Failure, Methamphetamine Use Disorder
Interventions
MUD Management (contingency management +/- adjunctive MUD pharmacotherapy), HF GDMT management
Other
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Sep 19, 2026, 9:33 PM EDT
Completed Not applicable Interventional Results available

Women's Recovery Group (WRG) Study - A Randomized Controlled Stage II Trial

NCT01318538
View directory record Official record
Conditions
Substance-Related Disorders, Alcohol-Related Disorders
Interventions
The Women's Recovery Group, Group Drug Counseling
Behavioral
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years and older
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
2
States / cities
Belmont, Massachusetts • Fall River, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 4, 2017 · Synced Sep 19, 2026, 9:33 PM EDT
Completed Not applicable Interventional

Effect of CBT Microinterventions on Mechanisms of Behavior Change Among Adults With AUD

NCT03661853
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Control, Functional Analysis, Cognitive Restructuring, Dealing With Cravings
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 26, 2021 · Synced Sep 19, 2026, 9:33 PM EDT
Completed Not applicable Interventional

RCT of an Integrative Intervention for Non-Treatment-Seeking Meth Users

NCT01926184
View directory record Official record
Conditions
HIV/AIDS, Stimulant Use Disorders
Interventions
Affect Regulation Treatment to Enhance Meth Intervention Success (ARTEMIS), Contingency Management (CM)
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Male only
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 20, 2022 · Synced Sep 19, 2026, 9:33 PM EDT
Completed Not applicable Interventional

In Vivo Experience With NRT to Increase Adherence and Smoking Abstinence

NCT02938403
View directory record Official record
Conditions
Smoking Reduction or Abstinence
Interventions
In vivo counseling, Standard Smoking Cessation Counseling
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
517 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 6, 2025 · Synced Sep 19, 2026, 9:33 PM EDT
Completed Phase 2 Interventional

Abstinence-Linked Money Management Multisite

NCT01327586
View directory record Official record
Conditions
Dual Diagnosis, Cocaine Abuse, Cocaine Dependence, Polysubstance Abuse
Interventions
ATM, Individual Drug Counseling
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
2
States / cities
Bridgeport, Connecticut • Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 29, 2020 · Synced Sep 19, 2026, 9:33 PM EDT
Completed Phase 2Phase 3 Interventional

Integrated Digital Intervention for Alcohol Use Disorder

NCT05748639
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Mobile health application, Medical Management
Other
Lead sponsor
Quit Genius
Industry
Eligibility
18 Years and older
Enrollment
242 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 19, 2025 · Synced Sep 19, 2026, 9:33 PM EDT
Completed Not applicable Interventional

Enhanced Smoking Cessation Intervention for Smokers Exposed to the World Trade Center (WTC) Disaster

NCT02538601
View directory record Official record
Conditions
Cigarette Smoking, Post Traumatic Stress Disorder, Signs and Symptoms, Respiratory
Interventions
CBT-A, CBT-S
Behavioral
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Sep 1, 2015 · Synced Sep 19, 2026, 9:33 PM EDT
Completed Not applicable Interventional Results available

Alcohol Screening and Pre-Operative Intervention Research Study

NCT03929562
View directory record Official record
Conditions
Alcohol Drinking
Interventions
Brief advice, Health coaching
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 75 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 14, 2022 · Synced Sep 19, 2026, 9:33 PM EDT