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ClinicalTrials.gov public records Last synced Oct 23, 2026, 11:35 AM EDT

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Showing 1–23 of 23 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Standard mouthpiece Clear all
Completed Not applicable Interventional Results available

Vitabreath Pilot in Chronic Obstructive Pulmonary Disease (COPD) Patients

NCT03349437
View directory record Official record
Conditions
COPD, Dyspnea
Interventions
Vitabreath Device, Pursed Lip Breathing
Device · Other
Lead sponsor
Philips Respironics
Industry
Eligibility
40 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
2
States / cities
Youngstown, Ohio • Jefferson Hills, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 8, 2019 · Synced Oct 23, 2026, 11:35 AM EDT
Completed Not applicable Interventional Results available

Accelerated Invisalign Therapy in Conjunction With Acceledent Aura

NCT02868554
View directory record Official record
Conditions
Malocclusion
Interventions
AcceleDent Aura, Accelerated Invisalign therapy
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 27, 2020 · Synced Oct 23, 2026, 11:35 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

The Effects of Filter During CPET on WOB and Aerosol Particle Concentrations

NCT04526925
View directory record Official record
Conditions
Transmission, Patient-Professional
Interventions
Respiratory filter in-line placed with the standard mouthpiece, Standard mouthpiece
Device · Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 26, 2023 · Synced Oct 23, 2026, 11:35 AM EDT
Recruiting Not applicable Interventional

Breathing Training and Exercise Capacity in Non-CFB

NCT05860803
View directory record Official record
Conditions
Non-cystic Fibrosis Bronchiectasis
Interventions
LungTrainers, LungTrainers Pulmonary Rehabilitation regime
Device · Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Oct 23, 2026, 11:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Metabolic Response of Unweighted Treadmill Walking

NCT07870434
View directory record Official record
Conditions
Metabolic Testing
Interventions
AlterG Treadmill, Metabolic Assessment
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 30 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
2
States / cities
East Meadow, New York • Garden City, New York
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 23, 2026, 11:35 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Comparison of 129Xe MRI With 19F MRI in CF Lung Disease

NCT03482960
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
Hyperpolarized Xenon gas, PFP
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 25, 2021 · Synced Oct 23, 2026, 11:35 AM EDT
Completed No phase listed Observational

Adiposity and Airway Inflammation in HIV-Associated Airway Disease

NCT02975258
View directory record Official record
Conditions
Asthma, HIV, Adiposity
Interventions
Blood draw, Questionnaires, Spirometry, Methacholine challenge test, Quantitative CT scans, Urine pregnancy test, Adipose biopsy, Exhaled nitric oxide measurement
Procedure · Other · Radiation
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 80 Years
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 13, 2017 · Synced Oct 23, 2026, 11:35 AM EDT
Terminated Not applicable Interventional Results available

Electronic Nose Identification of Fasting and Non-fasting Breath Profiles

NCT02419976
View directory record Official record
Conditions
Fasting
Interventions
a breath analysis using the Aeonose, Aeonose
Other · Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
879 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Oct 23, 2026, 11:35 AM EDT
Terminated Phase 4 Interventional Results available

A Study of Arformoterol Tartrate Inhalation Solution and Tiotropium Bromide on Re-hospitalization in Chronic Obstructive Pulmonary Disease (COPD) Subjects

NCT02275481
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
Arformoterol tartrate inhalation solution, Tiotropium
Drug
Lead sponsor
Sumitomo Pharma America, Inc.
Industry
Eligibility
55 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
28
States / cities
Birmingham, Alabama • Flagstaff, Arizona • Waterbury, Connecticut + 24 more
Source: ClinicalTrials.gov public record
Updated Jun 27, 2018 · Synced Oct 23, 2026, 11:35 AM EDT
Withdrawn Not applicable Interventional

Medicated Aerosol Delivery Using A Jet Nebulizer Versus A Vibrating Mesh Nebulizer in COPD Exacerbation

NCT03051971
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
Vibrating Mesh Nebulizer, Jet Nebulizer
Device
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
40 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 27, 2021 · Synced Oct 23, 2026, 11:35 AM EDT
Recruiting Not applicable Interventional

Spinal Cord Stimulation for Respiratory Rehabilitation in Patients With Chronic Spinal Cord Injury

NCT06019949
View directory record Official record
Conditions
Spinal Cord Injuries, Respiration Disorders
Interventions
Transcutaneous spinal cord stimulator, Respiratory Training
Device
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 13, 2026 · Synced Oct 23, 2026, 11:35 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Cerebral Blood Flow and Childhood Obstructive Sleep Apnea

NCT02995837
View directory record Official record
Conditions
Obstructive Sleep Apnea Syndrome
Interventions
Sleep Study, Neurocognitive Testing, CBF During Wakefulness, CBF During Sleep
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
6 Years to 12 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 9, 2024 · Synced Oct 23, 2026, 11:35 AM EDT
Withdrawn Not applicable Interventional

Validation of a Personal Breath Analyzer for Diet and Energy Expenditure Assessment and Management

NCT02981160
View directory record Official record
Conditions
Obesity
Interventions
Dietary
Other
Lead sponsor
Banner Health
Other
Eligibility
18 Years to 50 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
Gilbert, Arizona • Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 13, 2017 · Synced Oct 23, 2026, 11:35 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Evaluation of Regional Ventilation Using 19F MRI of Inert Perfluorinated Gases Mixed With Oxygen

NCT01710449
View directory record Official record
Conditions
COPD, Asthma, Cystic Fibrosis, Emphysema, Small Airways Diseases
Interventions
perfluorinated gas/oxygen mixture
Drug
Lead sponsor
Hal C Charles
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 9, 2013 · Synced Oct 23, 2026, 11:35 AM EDT
Completed Not applicable Interventional Results available

Respiratory Muscle Strength Training in Presbyphonia

NCT03557775
View directory record Official record
Conditions
Presbylarynx
Interventions
Inspiratory Muscle Strength Training (IMST), Expiratory Muscle Strength Training (EMST), Voice Exercises
Device · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
50 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 7, 2020 · Synced Oct 23, 2026, 11:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Respiratory Motor Control and Blood Pressure Regulation After Spinal Cord Injury

NCT02396823
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Respiratory Muscle Training
Behavioral
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2019
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 7, 2025 · Synced Oct 23, 2026, 11:35 AM EDT
Active, not recruiting No phase listed Observational

Long Term Follow up of Children Enrolled in the REDvent Study

NCT03709199
View directory record Official record
Conditions
Respiratory Distress Syndrome, Adult, Ventilator-Induced Lung Injury, Neurocognitive Dysfunction, Quality of Life, Respiration Disorders
Interventions
Ventilation Inhomogeneity, Diaphragm Ultrasound, Respiratory Inductance Plethysmography, Spirometry, Functional Residual Capacity, MIP/MEP, 6 minute walk test, Neurocognitive Testing, Emotional Health Assessment, Health Related Quality of Life, Functional Status, Respiratory Status Questionnaire
Diagnostic Test
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
1 Month to 18 Years
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 17, 2025 · Synced Oct 23, 2026, 11:35 AM EDT
Completed Not applicable Interventional

A Trial Assessing Chemo Mouthpiece Device With Best Supportive Care for Symptoms of Chemotherapy-Induced Oral Mucositis

NCT04595838
View directory record Official record
Conditions
Oral Mucositis
Interventions
Chemo Mouthpiece, Best Supportive Care only
Device · Other
Lead sponsor
Chemo Mouthpiece
Industry
Eligibility
18 Years to 80 Years
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
11
States / cities
Costa Mesa, California • Goshen, Indiana • Farmington Hills, Michigan + 8 more
Source: ClinicalTrials.gov public record
Updated Sep 18, 2023 · Synced Oct 23, 2026, 11:35 AM EDT
Withdrawn Not applicable Interventional

Effectiveness of Jamboxx Respiratory Therapy Device: Study 1

NCT03533400
View directory record Official record
Conditions
Spinal Cord Injuries, Respiratory Complication
Interventions
Jamboxx Respiratory Therapy Device, Jamboxx Musical Device
Device
Lead sponsor
My Music Machines Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated May 13, 2020 · Synced Oct 23, 2026, 11:35 AM EDT
Terminated Not applicable Interventional

The Effectiveness of the Jamboxx Respiratory Therapy Device: Study 3

NCT03547349
View directory record Official record
Conditions
Atelectases, Postoperative Pulmonary
Interventions
Digital Incentive Spirometer, Jamboxx Respiratory Therapy Device
Device
Lead sponsor
My Music Machines Inc.
Industry
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Aug 24, 2022 · Synced Oct 23, 2026, 11:35 AM EDT
Completed Not applicable Interventional

Photobiomodulation to Demonstrate Safety and Reduce the Incidence of Oral Mucositis in Adult Head & Neck Cancer Patients

NCT03972527
View directory record Official record
Conditions
Oral Mucositis (Ulcerative), Oral Mucositis (Ulcerative) Due to Radiation, Oral Mucositis (Ulcerative) Due to Antineoplastic Therapy, Head and Neck Cancer
Interventions
Photobiomodulation, Routine Oral Care and Analgesia
Device · Other
Lead sponsor
MuReva Phototherapy Inc.
Industry
Eligibility
22 Years and older
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
12
States / cities
Birmingham, Alabama • Long Beach, California • Miami, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Aug 21, 2024 · Synced Oct 23, 2026, 11:35 AM EDT
Terminated Phase 4 Interventional Results available

Comparison of Nebulizers in ED in Pediatric Asthma Patients

NCT01951378
View directory record Official record
Conditions
Asthma
Interventions
Hudson RCI® nebulizer, NebuTech® HDN® nebulizer, Albuterol
Device · Drug
Lead sponsor
Seton Healthcare Family
Other
Eligibility
3 Years to 17 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 8, 2021 · Synced Oct 23, 2026, 11:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

ABVN Phase 1 - Vagal Maneuvers

NCT07881276
View directory record Official record
Conditions
Healthy Subjects
Interventions
Vagal Maneuvers, Multi-Electrode Array (MEA) Recording
Other · Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 80 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 23, 2026, 11:35 AM EDT