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Conditions: Pressure Ulcer
Interventions: BlastX with negative pressure therapy; Device
Lead sponsor: SerenaGroup, Inc.; Network
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Kittanning, Pennsylvania

Conditions: Pain
Interventions: Lidocaine, Placebo; Drug
Lead sponsor: University of Florida; Other
Eligibility: 18 Years and older
Enrollment: 34 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2017
U.S. locations: 2
States / cities: Gainesville, Florida

Conditions: Wounds and Injuries
Interventions: Processed Amniotic Fluid, Standard of Care Wound Treatment Regimen; Drug · Other
Lead sponsor: University of Utah; Other
Eligibility: 18 Years to 85 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Healing
Interventions: Shapes by PolyMem dressing, Shapes by PolyMem Silver Dressing, Shapes by PolyMem on one site and Shapes by PolyMem Silver dressing on second site; Device
Lead sponsor: Ferris Mfg. Corp.; Industry
Eligibility: 18 Years and older
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2012
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Wound Chronic Draining, Wound Closure
Interventions: Platelet-rich fibrin (PRF); Device
Lead sponsor: Estar Medical dba Medical Technologies, LTD; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 3
States / cities: Bradenton, Florida • San Antonio, Texas

Conditions: Wounds and Injuries
Interventions: AR/101, Placebo; Drug
Lead sponsor: Arava Bio Tech Ltd.; Industry
Eligibility: 25 Years to 55 Years
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Coronary Artery Disease
Interventions: Quikclot Radial (QC) Pad; Device
Lead sponsor: Memorial Healthcare System; Other
Eligibility: 18 Years and older
Enrollment: 355 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Hollywood, Florida

Conditions: Nonmalignant Breast Conditions, Breast Cancer
Interventions: Sodium hypochlorite (Dakin's Solution), Chlorhexidine gluconate disk, Control, Occlusive Adhesive Dressing; Device · Procedure
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 90 Years
Enrollment: 110 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2013
U.S. locations: 2
States / cities: San Francisco, California • Rochester, Minnesota

Conditions: Skin Reaction to Mechanical, Thermal and Radiation Stimuli, Skin Sensitisation
Interventions: Sponsor incisional negative pressure wound therapy device and dressing, Standard of Care incisional negative pressure wound therapy system; Device
Lead sponsor: DeRoyal Industries, Inc.; Industry
Eligibility: 40 Years to 80 Years
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Knoxville, Tennessee

Conditions: Diabetic Foot Ulcer
Interventions: Lavior Diabetic Wound Gel, Smith & Nephew Solosite Gel Hydrogel Wound Dressing; Drug
Lead sponsor: Lavior Pharma Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Burns, Skin Burn Requiring Skin Graft
Interventions: P6 Low Adherent Dressing, Standard of Care (SOC); Device · Other
Lead sponsor: Milliken Healthcare Products, LLC; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 4
States / cities: Gainesville, Florida • Chapel Hill, North Carolina • Winston-Salem, North Carolina + 1 more

Conditions: Ostomy, Enterocutaneous Fistula
Interventions: Limpet, Control; Device
Lead sponsor: HealthPartners Institute; Other
Eligibility: 18 Years and older
Enrollment: 92 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 1
States / cities: Saint Paul, Minnesota

Conditions: Chronic Ulcer of Leg or Foot, Pressure Injury
Interventions: ConvaFoam; Device
Lead sponsor: ConvaTec Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 95 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 5
States / cities: Hagerstown, Maryland • Mineola, New York • Raleigh, North Carolina + 2 more

Conditions: Osteoarthritis of Knee, Edema, Wounds and Injuries
Interventions: ODIN1, Standard Care, Diagnostic Device Testing; Device · Other
Lead sponsor: Bioelectric Research Corporation; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016
U.S. locations: 2
States / cities: Las Vegas, Nevada

Conditions: Diabetic Foot Ulcer
Interventions: Dressing Application, Offloading; Procedure · Device
Lead sponsor: MiMedx Group, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 105 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 2
States / cities: Tulsa, Oklahoma • Roanoke, Virginia

Conditions: Chronic Pressure Ulcers
Interventions: PuraPly® Antimicrobial Wound Matrix, SOC for Pressure Ulcers; Device · Other
Lead sponsor: Organogenesis; Industry
Eligibility: 18 Years to 99 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 2
States / cities: Lake Success, New York • Mineola, New York

Conditions: Foot Ulcer, Diabetic
Interventions: DERMASEAL, Plasma Film, Standard of Care; Combination Product · Biological · Other
Lead sponsor: Vitruvian Medical Devices, Inc.; Industry
Eligibility: 21 Years and older
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 4
States / cities: Fresno, California • South Miami, Florida • Boardman, Ohio + 1 more

Conditions: Diabetic Foot Ulcer, Venous Leg Ulcer
Interventions: Synthetic Hybrid-Scale Fiber Matrix, Standard of Care, Living Cellular Skin Substitute; Device
Lead sponsor: Acera Surgical, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 6
States / cities: Vista, California • Jacksonville, Florida • Miami Beach, Florida + 3 more

Conditions: Non-healing Soft Tissue Wounds
Interventions: Procellera; Drug
Lead sponsor: Henry M. Jackson Foundation for the Advancement of Military Medicine; Other
Eligibility: 18 Years to 99 Years
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Diabetic Foot Ulcer
Interventions: Dual-layer perinatal tissue allograft, Three-layer fenestrated perinatal tissue allograft, Standard of care; Other
Lead sponsor: Samaritan Biologics; Industry
Eligibility: 18 Years and older
Enrollment: 170 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Monroe, North Carolina

Conditions: Venous Leg Ulcer
Interventions: TTAX01, Profore Compression Therapy, Cadexomer Iodine dressing; Biological · Other
Lead sponsor: BioTissue Holdings, Inc; Industry
Eligibility: 18 Years and older
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 6
States / cities: Carlsbad, California • Sylmar, California • North Chicago, Illinois + 3 more

Conditions: Healthy, Macromastia, Negative Pressure Therapy, Mammaplasty, Wound Healing
Interventions: Prophylactic ciNPWT, Standard Adhesive Dressing; Device · Other
Lead sponsor: Medstar Health Research Institute; Other
Eligibility: 18 Years and older · Female only
Enrollment: 92 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Burns, Contracture Scar, Surgical Injury
Interventions: Split Thickness Skin Graft (STSG), Base of wound fat graft with STSG Reconstruction (Autologous Layered Composite Grafting).; Procedure
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 2
States / cities: Pittsburgh, Pennsylvania

Conditions: Impaired Wound Healing, Postoperative Wound Infection-deep
Interventions: Dry Sterile Dressing, Metallic Silver Dressing, Ionic Silver Dressing; Other
Lead sponsor: Carilion Clinic; Other
Eligibility: 21 Years and older
Enrollment: 351 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Roanoke, Virginia

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Evaluating Blast-X® in Combination With Negative Pressure Wound Therapy

Lidocaine For Treatment of Post-operative Pain From Donor Sites Following Burn Injury.

Processed Amniotic Fluid (pAF) for the Treatment of Chronic Wounds

Evaluation of Preferences of Consumers and Clinicians for the Management of Shave Biopsy Sites With a PolyMem Formulation Dressing or Current Standard of Care.

Using TropoCells(R) Autologous Platelet-Rich Fibrin (PRF) to Treat Chronic Non-Healing Wounds

Safety and Efficacy of AR/101 in Accelerating Re-epithelialization of Split Thickness Wounds

Hemostasis With QuikClot® Radial® Pad Versus TR Band® After Transradial Artery Access

Trial of Drain Antisepsis After Tissue Expander Breast Reconstruction

Study Comparing iNPWT Dressing and Devices Affect on Bioburden Levels and Skin Condition After Seven Days

Restoring Tissue and Evaluating Novel Treatments for Efficacy in Wounds

Study of Low Adherent Dressing Versus the Standard of Care for the Management of Skin Grafts Over Thermal Burns

Novel Post-Surgical Incision Management to Prevent Ostomy Complications

A Prospective, Multi Centre, Interventional, Non-comparator, Open Label Study to Demonstrate the Efficacy, Safety, and Performance of ConvaFoam™ Dressings in the Management of Indicated Chronic Wound Types.

Microcurrent Stimulation Reduces Post-Operative Swelling and Healing Time Following Knee Replacement Surgery

DHACM vs Other Commercially Available Treatments

PuraPly® AM Plus the Standard of Care to Standard of Care Alone for the Management of Stage II-IV Pressure Ulcers.

Study to Assess the Safety of DERMASEAL for Diabetic Foot Ulcers

Assessment of Wound Closure Comparing Synthetic Hybrid-Scale Fiber Matrix With Standard of Care in Treating Diabetic Foot Ulcers (DFU) and With Living Cellular Skin Substitute in Treating Venous Leg Ulcers (VLU)

Clinical and Mechanistic Demonstration of a Bioelectric Dressing System for Non-healing Wound Management: A Phase II Trial

Evaluating the Efficacy of Perinatal Membrane Allografts in Addition to the Standard of Care for the Treatment of Non-healing Diabetic Foot Ulcers.

Subjects With Non-Healing Venous Leg Ulcers Treated With Standard Care Plus Cryopreserved Human Umbilical Cord (TTAX01)

NPWT Reduction Mammaplasty

Autologous Point-of-Care Adipose Therapy: Recent Injury

A Comparison of Post-Sternotomy Dressings