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Conditions: Burns, Pediatric ALL
Interventions: Face-to-face burn care, Telemedicine enhanced burn care; Procedure
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 0 Years to 80 Years
Enrollment: 130 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Surgical Wound, Bilateral Total Knee Arthroplasty, Wounds and Injuries, Joint Diseases, Musculoskeletal Diseases, Edema Leg, Joint Pain, Arthritis Knee
Interventions: Closed Incision Negative Pressure Therapy (ciNPT), Standard Silver-containing Dressing; Device
Lead sponsor: Solventum US LLC; Industry
Eligibility: 22 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 6
States / cities: Annapolis, Maryland • Baltimore, Maryland • Columbia, Maryland + 3 more

Conditions: Surgical Site Infection, Cesarean Section; Complications, Wound, Infection (Following Delivery), Postpartum Complication
Interventions: Steri3X, Control; Device · Other
Lead sponsor: University of Tennessee; Other
Eligibility: 16 Years and older · Female only
Enrollment: 1,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Diabetes, Morbid Obesity, Lymphedema, Orthopedic Disorder
Interventions: Avance Solo, Optifoam; Device · Other
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Diabetic Foot Ulcer
Interventions: AMNIOEXCEL Plus Amniotic Membrane, A Marketed Comparator, Standard of Care; Other · Device
Lead sponsor: Integra LifeSciences Corporation; Industry
Eligibility: 21 Years and older
Enrollment: 116 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 7
States / cities: Fresno, California • Los Angeles, California • Gainesville, Georgia + 3 more

Conditions: Diabetic Foot Ulcers (DFUs)
Interventions: E-GRAFT ™, FIBRACOL™; Other · Device
Lead sponsor: Skye Biologics Holdings, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Roanoke, Virginia

Conditions: Chronic Wounds
Interventions: Atteris Antimicrobial Skin and Wound Cleanser, Atteris Antimicrobial Barrier Film Dressing; Device
Lead sponsor: Atteris Healthcare, LLC; Industry
Eligibility: 18 Years to 89 Years
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Burn Wound
Interventions: Cellutome Device, Standard of Care; Device · Other
Lead sponsor: Lehigh Valley Hospital; Other
Eligibility: 18 Years and older
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: Allentown, Pennsylvania

Conditions: Osteoarthritis of Knee, Edema, Wounds and Injuries
Interventions: ODIN1, Standard Care, Diagnostic Device Testing; Device · Other
Lead sponsor: Bioelectric Research Corporation; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016
U.S. locations: 2
States / cities: Las Vegas, Nevada

Conditions: Pain
Interventions: Virtual Reality; Other
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 8 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Post-operative Complications, Surgical Site Infection, Surgical Wound Infection
Interventions: Prevena™ Incision Management System (PIMS), Standard-of-care Dressing; Device
Lead sponsor: KCI USA, Inc; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 92 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Venous Ulcer
Interventions: Standard Wound Care, Flexitouch System with Standard Wound Care; Device
Lead sponsor: Tactile Systems Technology, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 2
States / cities: Minneapolis, Minnesota • College Station, Texas

Conditions: Skin Reaction to Mechanical, Thermal and Radiation Stimuli, Skin Sensitisation
Interventions: Sponsor incisional negative pressure wound therapy device and dressing, Standard of Care incisional negative pressure wound therapy system; Device
Lead sponsor: DeRoyal Industries, Inc.; Industry
Eligibility: 40 Years to 80 Years
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Knoxville, Tennessee

Conditions: Diabetic Foot Ulcer, Venous Leg Ulcer
Interventions: Synthetic Hybrid-Scale Fiber Matrix, Standard of Care, Living Cellular Skin Substitute; Device
Lead sponsor: Acera Surgical, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 6
States / cities: Vista, California • Jacksonville, Florida • Miami Beach, Florida + 3 more

Conditions: Infections, Surgery
Interventions: Silverlon, Standard of Care Dressing; Other
Lead sponsor: Jorge Marcet; Other
Eligibility: 18 Years and older
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Diabetic Foot Ulcer
Interventions: Dermagraft, Comparator; Device · Other
Lead sponsor: Organogenesis; Industry
Eligibility: 18 Years and older
Enrollment: 314 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1998 – 2000
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Open Wound Abdominal Wall, Wound Non Healing
Interventions: NPWT Standard of Care plus Oasis wound product, Routine NPWT Standard of Care; Device
Lead sponsor: Kettering Health Network; Other
Eligibility: 18 Years to 89 Years
Enrollment: 43 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Kettering, Ohio

Conditions: Chronic Ulcer of Leg or Foot, Pressure Injury
Interventions: ConvaFoam; Device
Lead sponsor: ConvaTec Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 95 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 5
States / cities: Hagerstown, Maryland • Mineola, New York • Raleigh, North Carolina + 2 more

Conditions: Wound of Skin, Wound Heal, Surgical Wound, Full Thickness Skin Graft Healing
Interventions: 0.25% timolol gel with full-thickness skin grafts, Vaseline dressing; Drug · Other
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Open Wound, Wound Heal
Interventions: Micro/nanobubble (MNB) - Irrigation, 0.9% Normal Saline - Irrigation, Micro/nanobubble (MNB) - Negative Pressure Wound Therapy with Instillation (NPWTi), 0.9% Normal Saline - Negative Pressure Wound Therapy with Instillation (NPWTi); Drug · Other
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: Orange, California

Conditions: Surgical Site Infection
Interventions: Bioelectric dressing; Device
Lead sponsor: AdventHealth; Other
Eligibility: 18 Years to 90 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Kissimmee, Florida

Conditions: Complications Wounds, Negative Pressure Wound Therapy, Wound Healing Delayed, Incisional, Panniculectomy, Incisional Negative Pressure Wound Therapy, Incisional Vac, Wound Vac, Obese, Renal Failure, Kidney Transplant; Complications, Wound Healing Complication
Interventions: Incisional Negative Pressure Wound Therapy, Standard Closure with Skin Glue, PICO (Smith&Nephew), Dermabond; Procedure · Device
Lead sponsor: University of California, Davis; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Diabetic Foot, DFU, Diabetic Foot Ulcer, Foot Ulcer, Diabetic, Ulcer Foot, Venous Leg Ulcer, Leg Ulcer, Leg Ulcers Venous, Ulcer
Interventions: Standard of Care DFU, Tri-Membrane Wrap™ DFU, Membrane Wrap™ DFU, Membrane Wrap-Lite™ DFU, Membrane Wrap-Hydro™ DFU, Standard of Care VLU, Tri-Membrane Wrap™ VLU, Membrane Wrap™ VLU, Membrane Wrap-Lite™ VLU, Membrane Wrap-Hydro™ VLU; Other
Lead sponsor: BioLab Holdings; Industry
Eligibility: 18 Years and older
Enrollment: 650 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Philidelphia, Pennsylvania

Conditions: Venous Ulcer
Interventions: Apligraf, Standard of Care Dressing Group; Device · Other
Lead sponsor: Organogenesis; Industry
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Miami, Florida

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Telemedicine Optimized Burn Intervention

Evaluating Edema and Range of Motion Using Negative Pressure Therapy vs. Standard Surgical Dressing in Bilateral TKA

The Use of Steri3X for Prevention of Post-operative Wound Infections in Cesarean Sections

Closed Incision Negative Pressure Wound Therapy vs. Foam as Post Operative Dressing

AMNIOEXCEL® Plus vs A Marketed Comparator vs SOC in the Management of Diabetic Foot Ulcers

Clinical Trial Evaluating an Amnion Membrane Allograft for Use in the Management of Non- Healing Diabetic Foot Ulcers Versus Standard Of Care

A Study to Investigate Two Atteris Antimicrobial Products on Chronic Wound Healing.

Study Comparing Healing With Epidermal Fractional Blistergrafting (CellutomeTM) to Acellular Technique

Microcurrent Stimulation Reduces Post-Operative Swelling and Healing Time Following Knee Replacement Surgery

Virtual Reality for Pain Management in Burn Patients

The Use of the Prevena™ Incision Management System on Post-Surgical Cesarean Section Incisions

Flexitouch Treatment for Venous Ulcers

Study Comparing iNPWT Dressing and Devices Affect on Bioburden Levels and Skin Condition After Seven Days

Assessment of Wound Closure Comparing Synthetic Hybrid-Scale Fiber Matrix With Standard of Care in Treating Diabetic Foot Ulcers (DFU) and With Living Cellular Skin Substitute in Treating Venous Leg Ulcers (VLU)

Study Looking at the Effect of Silverlon on Post Operative Wound Infections

Pivotal Trial of Dermagraft(R) to Treat Diabetic Foot Ulcers

Effect of Oasis® Wound Matrix on Stage III and IV Trunk Pressure Wounds Treated With Negative Pressure Wound Therapy

A Prospective, Multi Centre, Interventional, Non-comparator, Open Label Study to Demonstrate the Efficacy, Safety, and Performance of ConvaFoam™ Dressings in the Management of Indicated Chronic Wound Types.

Efficacy and Safety of 0.25% Timolol Gel in Enhancing Full Thickness Skin Grafts Healing and Cosmetic Outcomes

Micro/Nanobubbles (MNBs) for Treatment of Acute and Chronic Wounds

Reducing Wound Infections Using Bioelectric Wound Dressings

Incisional Negative Pressure Wound Therapy in High Risk Patients Undergoing Panniculectomy: A Prospective Randomized Controlled Trial

Trial Assessing the Efficacy of Human Placental Membrane Products and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot Ulcers and Venous Leg Ulcers

A Post Marketing Study of Apligraf in Non-healing Wounds of Subjects With Venous Leg Ulcers