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ClinicalTrials.gov public records Last synced Oct 9, 2026, 10:04 AM EDT

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Showing 49–72 of 600 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Standard of Care for Pain Management Clear all
Completed Phase 2 Interventional

Safety and Activity of F14 for Management of Pain Following Total Knee Replacement

NCT03541655
View directory record Official record
Conditions
Total Knee Replacement, Postoperative Pain
Interventions
Bupivacaine HCl, F14 (celecoxib)
Drug
Lead sponsor
Arthritis Innovation Corporation
Industry
Eligibility
45 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
3
States / cities
Denver, Colorado • Dayton, Ohio • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 10, 2020 · Synced Oct 9, 2026, 10:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ventilatory Strategy for the Prevention of Atelectasis During Bronchoscopy Under General Anesthesia, VESPA Trial

NCT04311723
View directory record Official record
Conditions
Lung Disorder
Interventions
Anesthesia Procedure, Bronchoscopy
Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 22, 2024 · Synced Oct 9, 2026, 10:04 AM EDT
Completed Not applicable Interventional Results available

Virtual Reality for Pain Management in Orthopaedic Patients

NCT04152447
View directory record Official record
Conditions
Pain, Musculoskeletal
Interventions
VR device
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 15, 2022 · Synced Oct 9, 2026, 10:04 AM EDT
Recruiting Phase 4 Interventional

Precision Pain Management - A Randomized Clinical Trial Assessing the Efficacy of Suzetrigine on Postoperative Analgesia Among Surgical Patients at Higher Risk for Persistent Postoperative Opioid Use (POU)

NCT07672015
View directory record Official record
Conditions
Opioid Consumption, Postoperative
Interventions
Suzetrigine, Standard Care (in control arm)
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 9, 2026, 10:04 AM EDT
Completed Phase 4 Interventional Results available

Pudendal Enhancement of Enhanced Recovery After Surgery (ERAS) for Reconstructive Surgery (PEERS)

NCT04171050
View directory record Official record
Conditions
Pain Management
Interventions
Local anaesthetic, Pudendal Nerve Block plus anesthesia
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2025 · Synced Oct 9, 2026, 10:04 AM EDT
Completed Phase 4 Interventional

A Study Of Opioid Avoidance In Surgery Through Integrating Suzetrigine

NCT07257133
View directory record Official record
Conditions
Post Operative Pain
Interventions
Suzetrigine
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 9, 2026, 10:04 AM EDT
Terminated Not applicable Interventional

Empowered Relief: A One-Time Session to Help Postpartum Women Manage Ongoing Pain After Cesarean Delivery

NCT07090018
View directory record Official record
Conditions
Chronic Pain, Cesarean Section Complications
Interventions
Empowered Relief
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 9, 2026, 10:04 AM EDT
Not listed Not applicable Interventional

Intraoperative Cryoanalgesia for Extended Pain Management Following Thoracotomy

NCT03538340
View directory record Official record
Conditions
Chronic Post-thoracotomy Pain, Acute Post-thoracotomy Pain, Post-thoracotomy Pain Syndrome
Interventions
Thoracic Epidural, Intercostal Cryoanalgesia
Procedure
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 27, 2021 · Synced Oct 9, 2026, 10:04 AM EDT
Terminated Phase 1 Interventional

Quadratus Lumborum Nerve Blocks for Myomectomies

NCT03935815
View directory record Official record
Conditions
Laparoscopic Myomectomy, Quadratus Lumborum Nerve Block
Interventions
Ropivacaine injection, Sham treatment
Drug · Procedure
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older · Female only
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 28, 2021 · Synced Oct 9, 2026, 10:04 AM EDT
Not listed Not applicable Interventional

Impact of a Behavioral Tele-health Program on the Quality of Recovery for Patients Undergoing Total Joint Replacement Surgery

NCT05367050
View directory record Official record
Conditions
Opioid Dependence, Opioid Use, Pain, Joint
Interventions
Lucid Lane Therapy Program, Surgical Preparedness Course
Behavioral
Lead sponsor
Lucid Lane, Inc
Industry
Eligibility
21 Years to 90 Years
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated May 10, 2022 · Synced Oct 9, 2026, 10:04 AM EDT
Completed Phase 2 Interventional Results available

Video-assisted Thoracoscopic Surgery - Exparel Study

NCT04864210
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Liposomal bupivacaine, Bupivacaine
Drug
Lead sponsor
Nada Sadek
Other
Eligibility
18 Years to 80 Years
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 9, 2026, 10:04 AM EDT
Recruiting Not applicable Interventional

Effect of Virtual Reality Technology for Pain Management of Vaso-Occlusive Crisis in Patients With Sickle Cell Disease

NCT03353584
View directory record Official record
Conditions
Sickle Cell Disease, Vaso-occlusive Crisis
Interventions
Virtual Reality Therapy
Other
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
6 Years to 25 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
2
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 9, 2026, 10:04 AM EDT
Completed Phase 2 Interventional Results available

MOM's PAIN (Methylene Blue for Oral Mucositis' PAIN)

NCT03469284
View directory record Official record
Conditions
Malignant Neoplasm, Oral Pain, Stomatitis
Interventions
Best Practice, Methylene Blue
Other · Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced Oct 9, 2026, 10:04 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Does a Periaqueductal Gray-vagus Nerve Interface Malfunction Explain the Nat hx With Its Numerous Co-morbidities?

NCT06616363
View directory record Official record
Conditions
POTS - Postural Orthostatic Tachycardia Syndrome
Interventions
Questionnaires to be competed, Provide list of medication and lifetime events, Use phone App to record new life events, Will wear an activity monitor, Periodic 24-hour urine sodium check, A fMRI scan, A bedside tilt test will be performed, IV placed to collect blood samples, Stool Sample
Behavioral · Device · Other + 1 more
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
12 Years to 21 Years · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 9, 2026, 10:04 AM EDT
Recruiting Not applicable Interventional

General vs Spinal in Total Joint Arthroplasty (TJA)

NCT06747494
View directory record Official record
Conditions
Knee Osteoarthritis, Hip Osteoarthritis
Interventions
General Anesthesia, Spinal Anesthesia
Procedure
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
2,396 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Oct 9, 2026, 10:04 AM EDT
Recruiting Phase 4 Interventional

Exparel and Education to Avoid Opioids After Carpal Tunnel Release

NCT03867539
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Differing pain management strategy
Drug
Lead sponsor
Kettering Health Network
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
2
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Oct 9, 2026, 10:04 AM EDT
Terminated Not applicable Interventional

StimRouter™ for Pain Management in Post-stroke Shoulder Pain

NCT03093935
View directory record Official record
Conditions
Chronic Pain, Hemiplegic Shoulder Pain
Interventions
StimRouter Neuromodulation System
Device
Lead sponsor
Bioness Inc
Industry
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
2
States / cities
Miami, Florida • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 6, 2021 · Synced Oct 9, 2026, 10:04 AM EDT
Completed No phase listed Observational

Multimodal Analgesia With NSAID vs. Narcotics Alone After Shoulder Instability Surgery

NCT04018768
View directory record Official record
Conditions
Shoulder Pain
Interventions
ibuprofen 600 mg, Oxycodone/acetaminophen (Percocet) 5 mg/325
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 29, 2020 · Synced Oct 9, 2026, 10:04 AM EDT
Active, not recruiting Not applicable Interventional

A Collaborative Intervention for Improving Cancer Pain Management in Cancer Survivors

NCT06198010
View directory record Official record
Conditions
Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm, Hematopoietic and Lymphatic System Neoplasm
Interventions
Best Practice, Educational Intervention, Questionnaire Administration, Electronic Health Record Review, Health Telemonitoring, Cancer Pain Management
Other · Procedure · Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
680 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Scottsdale, Arizona • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 9, 2026, 10:04 AM EDT
Completed Not applicable Interventional Results available

Development of STEPPT

NCT06835439
View directory record Official record
Conditions
Pain, Back Pain, Low Back Pain, Chronic Pain, Neck Pain
Interventions
STEPPT Pilot, Standard Care (Control)
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
18 Years and older
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Oct 9, 2026, 10:04 AM EDT
Completed No phase listed Observational

Prospective Observational Clinical Study to Evaluate Patient Outcomes Following Pharmacogenetic Testing of Patients Undergoing Elective Surgical Procedures

NCT02605343
View directory record Official record
Conditions
Acute Pain, Surgery
Interventions
NeuroIDgenetix Test Panel
Other
Lead sponsor
AltheaDx
Industry
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 6, 2016 · Synced Oct 9, 2026, 10:04 AM EDT
Withdrawn Not applicable Interventional

Influence of Patient-Informed Choice in a Novel Treatment Model for LBP

NCT01744015
View directory record Official record
Conditions
Mechanical Low Back Pain
Interventions
Patient Decision Making tool, Standard of care
Behavioral · Other
Lead sponsor
Walsh University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 10, 2013 · Synced Oct 9, 2026, 10:04 AM EDT
Completed Phase 4 Interventional Results available

Effectiveness of Intensive Lipid Modification Medication in Preventing the Progression of Peripheral Arterial Disease (The ELIMIT Study)

NCT00687076
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Ezetimibe, Niaspan, Statin therapy, Standard care, Aspirin, Clopidogrel, Placebo Niaspan, Placebo Ezetimibe, Percutaneous transluminal angioplasty (PTA)
Drug · Behavioral · Procedure
Lead sponsor
Baylor College of Medicine
Other
Eligibility
40 Years to 80 Years
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 6, 2020 · Synced Oct 9, 2026, 10:04 AM EDT
Completed Not applicable Interventional

Post-market, Randomized, Controlled, Prospective Study Evaluating Intrathecal Pain Medication (IT) Versus Conventional Medical Management (CMM) in the Non-cancer, Refractory, Chronic Pain Population

NCT04096391
View directory record Official record
Conditions
Chronic Nonmalignant Pain, Pain, Intractable, Pain, Chronic
Interventions
Flowonix Prometra® II Programmable Infusion System, Pain Medicine
Device · Drug
Lead sponsor
Evolve Restorative Center
Other
Eligibility
22 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Santa Rosa, California
Source: ClinicalTrials.gov public record
Updated May 18, 2022 · Synced Oct 9, 2026, 10:04 AM EDT