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ClinicalTrials.gov public records Last synced Oct 1, 2026, 9:54 AM EDT

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Showing 25–38 of 38 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Standard of Care sinus surgery Clear all
Terminated Not applicable Interventional Accepts healthy volunteers

Management of Pediatric Chronic Rhinosinusitis in Asthmatic Children

NCT03336671
View directory record Official record
Conditions
Chronic Sinusitis, Adenoid Disease - Chronic
Interventions
Endoscopic Sinus surgery, Adenoidectomy
Procedure
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
6 Years to 12 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Oct 13, 2021 · Synced Oct 1, 2026, 9:54 AM EDT
Withdrawn Phase 3 Interventional Accepts healthy volunteers

Comparison of Topical Therapies in Post op Endoscopic Sinus Surgery Patients

NCT03303677
View directory record Official record
Conditions
Chronic Rhinosinusitis (Diagnosis)
Interventions
Saline Nasal, Budesonide Nasal, Topical Antibacterial (Product)
Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 30, 2018 · Synced Oct 1, 2026, 9:54 AM EDT
Completed Phase 4 Interventional Results available

The PIO II Study: In-office Post-op Placement of a Steroid-eluting Sinus Implant

NCT02668302
View directory record Official record
Conditions
Chronic Sinusitis, Ethmoidal
Interventions
Steroid-eluting sinus implant, Post-op standard of care
Combination Product · Other
Lead sponsor
Collin County Ear Nose & Throat
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Frisco, Texas
Source: ClinicalTrials.gov public record
Updated Oct 12, 2018 · Synced Oct 1, 2026, 9:54 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

QOL Outcomes in CRS With Polyps

NCT03144375
View directory record Official record
Conditions
Chronic Rhinosinusitis, Polyps
Interventions
Medical optimization and education, Standard of Care sinus surgery
Other · Procedure
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 100 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 8, 2017 · Synced Oct 1, 2026, 9:54 AM EDT
Enrolling by invitation Not applicable Interventional

Closed Sinus Augmentation With a Calcium Phosphosilicate Putty

NCT06507709
View directory record Official record
Conditions
Dental Implant, Maxillary Sinus Floor Augmentation
Interventions
Low volume CBCT
Procedure
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 85 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 1, 2026, 9:54 AM EDT
Recruiting No phase listed Observational

Measurable Residual Disease Detection Using Tumor-Informed ctDNA Surveillance After Curative-Intent Treatment in HPV-Independent Squamous Cell Carcinoma of the Head and Neck

NCT06744296
View directory record Official record
Conditions
Squamous Cell Carcinoma of Head and Neck
Interventions
Blood Draws and Tissue Sample(s)
Other
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 18, 2025 · Synced Oct 1, 2026, 9:54 AM EDT
Suspended Not applicable Interventional

Operative Procedures Vs. Endovascular Neurosurgery for Untreated Pseudotumor Trial

NCT02513914
View directory record Official record
Conditions
Pseudotumor Cerebri, Idiopathic Intracranial Hypertension (IIH)
Interventions
Dural Venous Sinus Stenting, Cerebrospinal Fluid Shunting
Device
Lead sponsor
St. Joseph's Hospital and Medical Center, Phoenix
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
2
States / cities
Phoenix, Arizona • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 26, 2024 · Synced Oct 1, 2026, 9:54 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

TIVA vs TXA in Sinus Surgery to Evaluate Operative Blood Loss and Surgical Field Quality

NCT05639686
View directory record Official record
Conditions
Rhinosinusitis Chronic, Sinus Cancer, Sinus Polyp, Encephalocele
Interventions
Tranexamic acid injection, Total Intravenous Anesthesia, Inhalational isoflurane
Drug
Lead sponsor
Our Lady of the Lake Hospital
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Mar 23, 2023 · Synced Oct 1, 2026, 9:54 AM EDT
Active, not recruiting Early Phase 1 Interventional Accepts healthy volunteers

In Vivo Imaging of the Olfactory Epithelium Using Confocal Laser Endomicroscopy

NCT07546617
View directory record Official record
Conditions
Endonasal Surgery, Endoscopic Sinus Surgery, Olfactory Dysfunction
Interventions
CONVIVO system, Fluorescein injection, USP 10%
Device · Drug
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 1, 2026, 9:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Radiographic Changes in the Maxillary Sinus Following Closed Sinus Augmentation

NCT06296459
View directory record Official record
Conditions
Dental Implant
Interventions
3D R100 scanner, Conventional Radiograph
Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 85 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 4, 2025 · Synced Oct 1, 2026, 9:54 AM EDT
Recruiting Phase 2 Interventional

Toripalimab With Chemotherapy for Sinus Cancer

NCT06940180
View directory record Official record
Conditions
Sinonasal Cancer, Paranasal Sinus Neoplasms, Squamous Cell Carcinoma, Sinonasal Undifferentiated Carcinoma, Locally Advanced Head and Neck Cancer
Interventions
Toripalimab, Carboplatin, Docetaxel, Radiation Therapy, Cisplatin
Drug · Radiation
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Oct 1, 2026, 9:54 AM EDT
Completed Not applicable Interventional

Comparison of AVF Versus AVG in Elderly Patients Starting Dialysis

NCT02981706
View directory record Official record
Conditions
Chronic Kidney Disease, Endstage Renal Disease
Interventions
Arteriovenous Fistula (AVF), Arteriovenous Graft (AVG)
Procedure
Lead sponsor
Columbia University
Other
Eligibility
65 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 30, 2019 · Synced Oct 1, 2026, 9:54 AM EDT
Terminated Phase 3 Interventional Results available

Add-on Dupilumab for AFRS as Postoperative Therapy (ADAPT)

NCT05545072
View directory record Official record
Conditions
Allergic Fungal Rhinosinusitis
Interventions
Dupilumab, Placebo, Intranasal Corticosteroid Sprays (INCS)
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
3
States / cities
Atlanta, Georgia • Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 8, 2025 · Synced Oct 1, 2026, 9:54 AM EDT
Not listed Not applicable Interventional

Impact of Anxiety on Cardiac Substrate Modification in Women With Atrial Fibrillation Undergoing Catheter Ablation

NCT02547584
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Catheter ablation
Procedure
Lead sponsor
Texas Cardiac Arrhythmia Research Foundation
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 10, 2019 · Synced Oct 1, 2026, 9:54 AM EDT