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ClinicalTrials.gov public records Last synced Nov 14, 2026, 10:42 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 917 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Standard of care for pain Clear all

Conditions: Cervical Radiculopathy, Cervical Radicular Pain
Interventions: Cervical epidural steroid injection; Procedure
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 90 Years
Enrollment: 78 participants
Timeline: 2020 – 2022
U.S. locations: 2
States / cities: Washington D.C., District of Columbia • Baltimore, Maryland

Conditions: Chronic Low-back Pain
Interventions: Flowly (TMC-CP01); Device
Lead sponsor: Ajay Wasan, MD, Msc; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Blood Donors
Interventions: Competence, Autonomy, Relatedness; Behavioral
Lead sponsor: Ohio University; Other
Eligibility: 16 Years to 24 Years
Enrollment: 2,580 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Athens, Ohio

Conditions: Anxiety, Opioid Use
Interventions: hypnosis therapy; Behavioral
Lead sponsor: Foundation for Orthopaedic Research and Education; Other
Eligibility: 18 Years and older
Enrollment: 144 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Knee Osteoarthritis, Total Knee Arthroplasty (TKA)
Interventions: Pain Scale/Medication Log; Other
Lead sponsor: Endeavor Health; Other
Eligibility: 18 Years and older
Enrollment: 375 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Skokie, Illinois

Conditions: Breast Cancer
Interventions: Not listed
Lead sponsor: Walter Reed Army Medical Center; Federal
Eligibility: 18 Years and older · Female only
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Osteoarthritis
Interventions: Dextrose Prolotherapy, Saline Prolotherapy, At-home physical therapy exercise group; Procedure · Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 40 Years to 70 Years
Enrollment: 98 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2016
U.S. locations: 2
States / cities: Madison, Wisconsin

Conditions: Kidney Stone, Pain, Postoperative, Anxiety Postoperative
Interventions: Meditation; Behavioral
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 12 Years and older
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 2
States / cities: Philadelphia, Pennsylvania

Conditions: Migraine, Migraine in Adolescence
Interventions: BREATHE with Headache (BREATHE-HA), Enhanced Standard-of-Care: Headache Education; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 12 Years to 17 Years
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Osteoarthritis
Interventions: Standard of care for osteoarthritis treatment, Conjoint Analysis for Osteoarthritis; Behavioral
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 65 Years to 95 Years
Enrollment: 182 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Sickle Cell Disease
Interventions: Morphine, Methadone; Drug
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 7 Years to 40 Years
Enrollment: 47 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Prostate Cancer, Prostate Adenocarcinoma
Interventions: Blood Collection During Standard of Care Treatment; Other
Lead sponsor: H. Lee Moffitt Cancer Center and Research Institute; Other
Eligibility: 18 Years and older · Male only
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Pain, Postoperative
Interventions: Buprenorphine Sublingual Spray, Morphine, Oxycodone Hydrochloride, Zofran; Drug
Lead sponsor: INSYS Therapeutics Inc; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 2
States / cities: Pasadena, California • Murray, Utah

Conditions: Dental Crowding, Dental Occlusion, Traumatic, Endodontic Disease, Orthodontic Treatment, Endodontic Lesions, PeriodontalConditions, Oral Surgery Conditions, Tooth Extractions, Local Anesthesia, Traumatic Dental Pain, TMJ, Orthodontics, Endodontic Histopathology, Periodontal Diseases
Interventions: dental-dedicated MRI (ddMRI); Device
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 500 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Tonsillectomy
Interventions: Celecoxib, Placebo, Acetaminophen, Oxycodone; Drug · Other
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 3 Years to 11 Years
Enrollment: 172 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Contraceptive Devices, Long-Acting Reversible Contraception, Analgesia, Adolescent Health, Gynecology
Interventions: Nitrous oxide gas for inhalation, Oxygen Gas for Inhalation; Drug
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 14 Years to 24 Years · Female only
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Postoperative Pain, Medication Side Effects, Narcotic Requirement
Interventions: IV acetaminophen; Drug
Lead sponsor: Gundersen Lutheran Medical Foundation; Other
Eligibility: 18 Years to 90 Years
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: La Crosse, Wisconsin

Conditions: Obesity, Pain
Interventions: Use of PDA + support to reduce weight and pain, MOVE! level 2 group weight loss counseling; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Hines, Illinois

Conditions: Acute Pain, Low Back Pain, Mechanical
Interventions: Supported-Self Management (SSM), Spinal Manipulation Therapy (SMT), SMT + SSM, Standard Medical Care (SMC); Behavioral · Other · Combination Product + 1 more
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 1,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 3
States / cities: Minneapolis, Minnesota • Pittsburgh, Pennsylvania • Seattle, Washington

Conditions: Chronic Pain
Interventions: Intervention, Control; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Hip Pain Chronic, Hip Pain, Physical Medicine and Rehabilitation
Interventions: HIPS-1, HIPS-2; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Back Pain Lower Back Chronic, Chronic Pain, Musculoskeletal Pain
Interventions: Digital Musculoskeletal (MSK) Program, Transcutaneous Electrical Nerve Stimulation (TENS), Standard of Care (SOC); Behavioral · Device · Other
Lead sponsor: Hinge Health, Inc; Industry
Eligibility: 18 Years and older
Enrollment: 196 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Eden Prairie, Minnesota

Conditions: Contraception
Interventions: Music; Behavioral
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 2
States / cities: New York, New York

Conditions: Chronic Pain
Interventions: Pramipexole Oral Tablet, Placebo; Drug · Other
Lead sponsor: University of New Mexico; Other
Eligibility: 18 Years and older
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Search by objective public record fields.

Non-organic Signs to Predict Outcomes for Neck Pain

VANISH for Chronic Low Back Pain

Blood Donor Competence, Autonomy and Relatedness Enhancement

Effects of Hypnosis Therapy on Outcomes in Shoulder Replacement Therapy

How Variations in Pharmacogenomic Profiles Affect Pain and Narcotic Needs Following Total Knee Arthroplasty (TKA)

PASSION - P Trial: Ph Adjusted Sulfur-Colloid, Sentinel Initiative ON Pain Trial

Joint Injections for Osteoarthritic Knee Pain

Meditation Effects on Discomfort, Pain InTerference, and AnxieTy After urEteroscopy

Headache Education and Awareness vs. Daily Mindfulness Strategies - Understanding Pain

Conjoint Analysis of Treatment Preferences for Osteoarthritis

Methadone in Pediatric and Adult Sickle Cell Patients

Assess Gamma H2AX Positivity in Circulating Prostate Cancer Cells Before and After Radium 223

Study of Buprenorphine Sublingual Spray Versus Standard of Care Narcotic Therapy for the Treatment of Post-Operative Pain

Exploration of the Utility of Dental-dedicated MRI for Dentistry

Celecoxib After Tonsillectomy

Nitrous Oxide for Pain Management During IUD Insertion in Nulliparous Adolescent Women

Pain Control After Minimally Invasive Coronary Artery Bypass Grafting

PDA+: A Personal Digital Assistant for Obesity Treatment

Spinal Manipulation and Patient Self-Management for Preventing Acute to Chronic Back Pain

Pilot Testing of a Behavioral Intervention for Chronic Pain in Individuals With HIV

HIPS Feasibility Randomized Controlled Trial

Examining the Impact of a Digital Health Program and TENS Device for Patients With Chronic Low Back Pain

Music as a Nonpharmacologic Approach to Pain Control With Intrauterine Device Placement

Non-Opioid Pramipexole and Pain