- Conditions
- Analgesia
- Interventions
- F14 (sustained release celecoxib)
- Drug
- Lead sponsor
- Arthritis Innovation Corporation
- Industry
- Eligibility
- 45 Years to 80 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2027 – 2028
- U.S. locations
- 2
- States / cities
- Denver, Colorado • San Antonio, Texas
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Showing 25–48
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- Conditions
- Knee Arthroplasty
- Interventions
- Knee Flexion, Standard Care
- Other · Procedure
- Lead sponsor
- Icahn School of Medicine at Mount Sinai
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Opioid Use, Opioid Dependence, Knee Pain Chronic, Knee Osteoarthritis
- Interventions
- Improved Opioid-Tapering Instructions, Clinical Patient Educator
- Drug · Behavioral
- Lead sponsor
- Brigham and Women's Hospital
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Osteoarthritis
- Interventions
- Total Knee Arthroplasty
- Other
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- Up to 75 Years
- Enrollment
- 28 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2012
- U.S. locations
- 2
- States / cities
- Aurora, Colorado • Denver, Colorado
- Conditions
- Knee Replacement, Total
- Interventions
- TKA Journey - patient education, Optimized Rehab Scheduling, Usual Rehab
- Behavioral · Other
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 275 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Hip Fracture, Osteoarthritis, Femur Head Necrosis
- Interventions
- Essential amino acid supplement, Ketoconazole, Placebo
- Drug
- Lead sponsor
- University of Arkansas
- Other
- Eligibility
- 30 Years to 80 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2012
- U.S. locations
- 1
- States / cities
- Little Rock, Arkansas
- Conditions
- Knee Arthritis
- Interventions
- trumatch group, control group
- Procedure
- Lead sponsor
- VA Palo Alto Health Care System
- Federal
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 64 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2013
- U.S. locations
- 1
- States / cities
- Palo Alto, California
- Conditions
- Total Knee Arthroplasty
- Interventions
- 3D-Printed Mechanical Balancer
- Device
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Periprosthetic Joint Infection
- Interventions
- Single Debridement, Antibiotics and Implant Retention, Planned Double Debridement, Antibiotics and Implant Retention
- Procedure
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 490 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2032
- U.S. locations
- 2
- States / cities
- Jacksonville, Florida • Rochester, Minnesota
- Conditions
- Fat Consumption, Inflammatory Markers
- Interventions
- Inflammatory markers test in blood prior to surgery, Inflammatory markers test in CSF (cerebrospinal fluid), MOCA test, CAM-3D
- Diagnostic Test
- Lead sponsor
- Ohio State University
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 62 participants
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Degenerative Arthritis
- Interventions
- Orthosensor™ VERASENSE™ Knee System
- Device
- Lead sponsor
- LifeBridge Health
- Other
- Eligibility
- 45 Years to 80 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Obesity, Osteoarthritis
- Interventions
- Not listed
- Lead sponsor
- Geisinger Clinic
- Other
- Eligibility
- 22 Years to 75 Years
- Enrollment
- 289 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2024
- U.S. locations
- 1
- States / cities
- Danville, Pennsylvania
- Conditions
- Unilateral Knee Arthroplasty
- Interventions
- Preop acetaminophen IV, Preop orphenadrine IV, Postop oral oxycodone & acetaminophen, Postop hydromorphone IV, Postop oral orphenadrine, Postop oral oxycodone, Postop acetaminophen IV, Postop orphenadrine IV
- Drug
- Lead sponsor
- AdventHealth
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 180 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Winter Park, Florida
- Conditions
- Knee Arthroplasty
- Interventions
- Knee Arthroplasty
- Device
- Lead sponsor
- ZipLine Medical Inc.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 41 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Norristown, Pennsylvania
- Conditions
- Osteoarthritis, Post-traumatic; Arthrosis
- Interventions
- methylprednisolone acetate, active comparator
- Drug
- Lead sponsor
- New Lexington Clinic
- Other
- Eligibility
- 18 Years to 95 Years
- Enrollment
- 101 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2008
- U.S. locations
- 1
- States / cities
- Lexington, Kentucky
- Conditions
- Knee Osteoarthritis, Knee Arthritis, Knee Arthropathy
- Interventions
- Physical Therapy, In-home Exercise Equipment
- Other
- Lead sponsor
- Campbell University, Incorporated
- Other
- Eligibility
- Up to 65 Years
- Enrollment
- 51 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2019
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Osteoarthritis, Knee
- Interventions
- Telerehabilitation using the KinexConnect system for rehabilitation after TKA., Traditional outpatient PT for rehabilitation after TKA.
- Behavioral
- Lead sponsor
- Kinex Medical Company, LLC
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2023
- U.S. locations
- 1
- States / cities
- Des Moines, Iowa
- Conditions
- Knee Arthroplasty
- Interventions
- Standard Physical Therapy, Physical therapist discuss aerobic physical activity, Physical activity session
- Behavioral
- Lead sponsor
- University of South Carolina
- Other
- Eligibility
- 40 Years to 79 Years
- Enrollment
- 45 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2020
- U.S. locations
- 2
- States / cities
- Columbia, South Carolina
- Conditions
- Knee Arthroplasty
- Interventions
- video or education session in addition to standard consent
- Other
- Lead sponsor
- jasvinder singh
- Federal
- Eligibility
- 18 Years to 110 Years
- Enrollment
- 176 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2009
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota
- Conditions
- Knee Arthroplasty, Total
- Interventions
- ConforMIS custom total knee
- Device
- Lead sponsor
- University of Missouri-Columbia
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 28 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- Columbia, Missouri
- Conditions
- Osteoarthritis
- Interventions
- Neuromuscular Electrical Stimulation (NMES), Standard Rehabilitation Protocol
- Device · Other
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 50 Years to 85 Years
- Enrollment
- 66 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2011
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- Osteoarthritis of the Knee
- Interventions
- Instrument
- Other
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2014
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Total Knee Replacement Surgery, Total Hip Replacement Surgery
- Interventions
- XPERIENCE Advanced Surgical Irrigation, Standard of Care Irrigation
- Device · Other
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023
- U.S. locations
- 1
- States / cities
- Jacksonville, Florida
- Conditions
- Total Knee Replacement
- Interventions
- CPM, GAPFLEX
- Device
- Lead sponsor
- Xeras Medical Technologies
- Industry
- Eligibility
- 50 Years and older
- Enrollment
- 28 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2017
- U.S. locations
- 2
- States / cities
- San Antonio, Texas