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Showing 1–24 of 247 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Standard weight loss intervention Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Nutrition, Exercise, and Technology for Weight Loss

NCT02731768
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Standard, Social support-enhanced, Fitbit Zip, Digital body weight scale
Behavioral · Device
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 17, 2018 · Synced Sep 2, 2026, 5:02 PM EDT
Completed Phase 2Phase 3 Interventional

Delivering an Evidence-Based Lifestyle Intervention Via the Internet: A Randomized Controlled Study

NCT01043718
View directory record Official record
Conditions
Obesity
Interventions
More-Intensive, Less-Intensive
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 13, 2016 · Synced Sep 2, 2026, 5:02 PM EDT
Completed Phase 2 Interventional

The Comparison of a Technology-Based System and an In-Person Behavioral Weight Loss Intervention

NCT01134874
View directory record Official record
Conditions
Obesity
Interventions
Standard weight loss intervention, Standard weight loss intervention plus technology, Technology only
Behavioral
Lead sponsor
John M. Jakicic, PhD
Other
Eligibility
18 Years to 55 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 4, 2015 · Synced Sep 2, 2026, 5:02 PM EDT
Completed Not applicable Interventional Results available

Auricular Acupuncture in the Treatment of Obesity

NCT02269371
View directory record Official record
Conditions
Obesity
Interventions
Auricular Acupuncture, Sham Acupuncture
Other
Lead sponsor
Mike O'Callaghan Military Hospital
Federal
Eligibility
18 Years and older
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Aug 5, 2024 · Synced Sep 2, 2026, 5:02 PM EDT
Completed Phase 2 Interventional

Innovative Approaches to Diet, Exercise and Activity

NCT01131871
View directory record Official record
Conditions
Body Weight
Interventions
Standard Behavioral Weight Loss Intervention, Enhanced Weight Loss Intervention
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 35 Years
Enrollment
471 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 4, 2015 · Synced Sep 2, 2026, 5:02 PM EDT
Recruiting Phase 2 Interventional

Uterine Preservation Via Lifestyle Transformation

NCT05903131
View directory record Official record
Conditions
Endometrial Hyperplasia, Grade 1 Endometrial Cancer
Interventions
Telemedicine behavioral weight intervention, Progestin, Enhanced usual care, Levonorgestrel-releasing IUD.
Behavioral · Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
3
States / cities
St Louis, Missouri • Albuquerque, New Mexico • Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jan 19, 2026 · Synced Sep 2, 2026, 5:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Bitter Taste and Weight Loss in Women

NCT01856660
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Low-Carbohydrate Diet, Low-fat Diet
Behavioral
Lead sponsor
Rutgers University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 23, 2021 · Synced Sep 2, 2026, 5:02 PM EDT
Completed Phase 2 Interventional

Diet, Exercise, and Breastfeeding Intervention Program for Women With Gestational Diabetes (DEBI Trial)

NCT00460018
View directory record Official record
Conditions
Gestational Diabetes Mellitus
Interventions
Diet, Exercise, and Breastfeeding Intervention
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
20 Years to 45 Years · Female only
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2005
U.S. locations
5
States / cities
Oakland, California • San Francisco, California • Santa Clara, California + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 18, 2009 · Synced Sep 2, 2026, 5:02 PM EDT
Completed Not applicable Interventional

Feasibility and Preliminary Efficacy of a Reverse Diet as a Novel Weight Loss Maintenance Strategy for Weight-Reduced Adults With Overweight/Obesity

NCT03560635
View directory record Official record
Conditions
Overweight and Obesity, Weight Loss Maintenance, Dietary Habits
Interventions
Weight Loss Maintenance (Control vs. Reverse Diet)
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
21 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 18, 2022 · Synced Sep 2, 2026, 5:02 PM EDT
Completed Not applicable Interventional

Effects of Wolffia Globosa (Mankai) in Patients Undergoing Bariatric Surgery.

NCT03999632
View directory record Official record
Conditions
Bariatric Surgery Candidate, Diet Modification
Interventions
Dietary modification with introduction of Mankai
Other
Lead sponsor
Cleveland Clinic Florida
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Feb 3, 2021 · Synced Sep 2, 2026, 5:02 PM EDT
Completed Not applicable Interventional

Environmental and Acceptance-Based Innovations for Weight Loss Maintenance

NCT01858714
View directory record Official record
Conditions
Obesity, Overweight, Weight Loss
Interventions
Behavior Therapy for Weight Loss, Behavior Therapy + Environment, Acceptance-based Behavior Therapy + Environment
Behavioral
Lead sponsor
Drexel University
Other
Eligibility
18 Years to 70 Years
Enrollment
238 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 4, 2016 · Synced Sep 2, 2026, 5:02 PM EDT
Completed Not applicable Interventional

Dietary Oxysterols and β-Cell Function Among African Americans

NCT05072587
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Plant-based diet with no oxysterols, Standard ADA Diet (SADA)
Behavioral
Lead sponsor
Morehouse School of Medicine
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Sep 2, 2026, 5:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Lifestyle Intervention Forever: Healthy Weight for Pregnancy and Birth (Pilot Study)

NCT01693666
View directory record Official record
Conditions
Pregnancy, Obesity, Weight Gain, Obstetric Complications
Interventions
Lifestyle intervention
Behavioral
Lead sponsor
St. Louis University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 1, 2015 · Synced Sep 2, 2026, 5:02 PM EDT
Completed Not applicable Interventional

Obesity Surgery and Kidney Transplant for Patients With Obesity and Renal Failure

NCT02128802
View directory record Official record
Conditions
Severe Obesity, Renal Failure
Interventions
Gastric Bypass, Weight Loss Program
Procedure · Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 59 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2024
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 9, 2025 · Synced Sep 2, 2026, 5:02 PM EDT
Completed Not applicable Interventional Results available

Feasibility of a Campaign Intervention Compared to a Standard Behavioral Weight Loss Intervention in Overweight and Obese Adults

NCT01803737
View directory record Official record
Conditions
Weight Loss
Interventions
Standard Behavioral Weight Loss Intervention (SBWL), Campaign Intervention (CI)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 55 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 16, 2014 · Synced Sep 2, 2026, 5:02 PM EDT
Completed Not applicable Interventional

Volume,Sodium and Blood Pressure Management in HD

NCT01766882
View directory record Official record
Conditions
End Stage Renal Failure
Interventions
Lower sodium intervention, Progressive Challenge to Post Dialysis Weight
Behavioral · Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
2
States / cities
Ann Arbor, Michigan • Livonia, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 14, 2016 · Synced Sep 2, 2026, 5:02 PM EDT
Completed Not applicable Interventional Results available

Reach for Health Study: Obesity-related Mechanisms and Mortality in Breast Cancer Survivors

NCT01302379
View directory record Official record
Conditions
Breast Neoplasms
Interventions
Metformin, Placebo, Lifestyle intervention, Standard printed dietary guidelines
Drug · Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
Female only
Enrollment
333 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 4, 2020 · Synced Sep 2, 2026, 5:02 PM EDT
Not yet recruiting Not applicable Interventional

Assessing Follow up Trajectories in Eating, Routines, and Weight After GLP-1

NCT07701460
View directory record Official record
Conditions
Weight Maintenance
Interventions
Digital Behavioral Application
Behavioral
Lead sponsor
Tufts University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Sep 2, 2026, 5:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Combined Eating Disorder and Weight Loss Online Guided-Self Help Intervention

NCT04248686
View directory record Official record
Conditions
Eating Disorders, Obesity
Interventions
CoED Online Intervention
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 6, 2022 · Synced Sep 2, 2026, 5:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Behavioral Lifestyle Intervention for Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) in Adults

NCT06121999
View directory record Official record
Conditions
Metabolic Associated-dysfunction Steatotic Liver Disease (MASLD), Metabolic Associated-dysfunction Steatohepatitis (MASH)
Interventions
Standard of care acceptance-based behavioral weight loss program, Occupational therapy dietary and lifestyle modifications
Behavioral
Lead sponsor
Grand Valley State University
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Wyoming, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced Sep 2, 2026, 5:02 PM EDT
Recruiting Not applicable Interventional

Lifestyle Change Implementation Research Network at PRC at UMass Chan

NCT07481305
View directory record Official record
Conditions
GLP - 1
Interventions
Digital Lifestyle Coaching Program
Other
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Sep 2, 2026, 5:02 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Piloting a Generative Artificial Intelligence Chatbot in a Mobile Weight Loss Program

NCT07534254
View directory record Official record
Conditions
Overweight and/or Obesity
Interventions
AGILE Intervention, Chatbot
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 39 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Sep 2, 2026, 5:02 PM EDT
Not yet recruiting Not applicable Interventional

Optimization of Dietary Adherence in a Mobile Weight Loss Intervention

NCT07582536
View directory record Official record
Conditions
Overweight and/or Obesity
Interventions
Core, Switch to Simplified Diet Monitoring, Goal Autonomy/Planning, Just-in-time (JIT) Messaging, Coach Sessions
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
580 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Sep 2, 2026, 5:02 PM EDT
Completed Not applicable Interventional Results available

Targeting Obesity to Optimize Health in Cardiac Rehab (TOPCARE)

NCT03423238
View directory record Official record
Conditions
Obesity, Weight Loss, CHD - Coronary Heart Disease
Interventions
Exercise, Health Education, Exercise Compliance, Calorie-Restricted Diet, Behavioral Modification, Weight-Loss Compliance, Dietary Counseling
Other · Behavioral · Dietary Supplement
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
40 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 22, 2021 · Synced Sep 2, 2026, 5:02 PM EDT