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ClinicalTrials.gov public records Last synced Sep 7, 2026, 1:52 AM EDT

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Showing 1–24 of 50 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Bariatric - Sleeve Gastrectomy Staple Line Reinforcement, Gynecology - Vaginal Cuff Closure
Interventions
Robotic Suturing of gastric sleeve oversew and vaginal cuff closure
Device
Lead sponsor
Ethicon, Inc.
Industry
Eligibility
18 Years and older
Enrollment
161 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
4
States / cities
Miami, Florida • Albany, New York • New York, New York
Completed Phase 4 Interventional Results available

PleuraSeal Post Market Study (Europe)

NCT00704171
Conditions
Lung Disease, Pulmonary Lobectomy
Interventions
Standard Tissue Closure Techniques, PleuraSeal Lung Sealant System
Procedure · Device
Lead sponsor
Integra LifeSciences Corporation
Industry
Eligibility
18 Years and older
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Bedford, Massachusetts
Conditions
Deep Full-thickness Burn Injury (Disorder)
Interventions
realSKIN (skin xenotransplant), Human Cadaver Allograft
Biological
Lead sponsor
XenoTherapeutics, Inc.
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
Augusta, Georgia • Boston, Massachusetts
Completed Phase 2 Interventional Accepts healthy volunteers Results available

A Comparison of Metallic Staples Versus Absorbable Staples After a Cesarean Section (C-Section)

NCT01198691
Conditions
Cesarean Section
Interventions
Insorb absorbable staples, Insorb
Device
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Cincinnati, Ohio
Terminated Not applicable Interventional Results available

Staples Versus Suture for Cesarean Wound Closure

NCT01008449
Conditions
Wound
Interventions
Surgical staples, Absorbable Surgical Suture
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
16 Years and older · Female only
Enrollment
398 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Birmingham, Alabama
Completed Not applicable Interventional Results available

NeoMend ProGEL™ Pleural Air Leak Sealant Post-Approval Study

NCT01394978
Conditions
Lung Cancer, Lung Tumor
Interventions
Control, ProGEL Pleural Air Leak Sealant with standard surgical closure, ProGEL Pleural Air Leak Sealant without standard surgical closure
Other · Device
Lead sponsor
C. R. Bard
Industry
Eligibility
18 Years and older
Enrollment
444 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
18
States / cities
Birmingham, Alabama • Jacksonville, Florida • Tampa, Florida + 10 more
Conditions
Obesity, Severe, Cesarean Section
Interventions
Absorbable subcuticular suture, Stainless steel staples
Device
Lead sponsor
MemorialCare Health System
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
238 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
4
States / cities
Long Beach, California • Orange, California
Conditions
Surgery
Interventions
Surgical wound closure techniques, Surgical wound closure techniques (Comparator)
Procedure
Lead sponsor
University of Kentucky
Other
Eligibility
18 Years and older
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Lexington, Kentucky
Conditions
Laparotomy
Interventions
Laparotomy, ICG, Spectrum NIR imaging system
Procedure · Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
8
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 5 more
Terminated Not applicable Interventional Accepts healthy volunteers

Sutures vs. Staples Skin Closure After C-section in Obese Patients

NCT01820221
Conditions
Obesity, Pregnancy
Interventions
Suture vs. staples closure method after c-section in obese women.
Procedure
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Little Rock, Arkansas
Conditions
Pregnancy
Interventions
Subcuticular monocryl suture, Subcuticular absorbable staple using Insorb device
Procedure · Device
Lead sponsor
Inova Health Care Services
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
237 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Falls Church, Virginia
Conditions
Wounds and Injuries, Compartment Syndrome
Interventions
DermaClose fasciotomy closure, Vessel loop
Device
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Columbia, Missouri
Conditions
Arthroplasty, Replacement, Knee
Interventions
Zip Surgical Skin Closure, Steel Staples
Device
Lead sponsor
ZipLine Medical Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Indianapolis, Indiana
Conditions
Traumatic Lacerations or Surgical Incisions
Interventions
BondEase, CWCD
Device · Procedure
Lead sponsor
OptMed, Inc.
Industry
Eligibility
18 Years and older
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
6
States / cities
Orlando, Florida • Chicago, Illinois • Chevy Chase, Maryland + 3 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Clinical Trial of Subcuticular Staples Versus Subcuticular Suture for Cesarean Section Skin Closure

NCT01753518
Conditions
Surgical Wound
Interventions
Subcuticular suture, Subcuticular staple
Device
Lead sponsor
Margaret L. Dow, M.D.
Other
Eligibility
18 Years and older · Female only
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Wound Heal
Interventions
DERMABOND, Staples
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Subcuticular Absorbable Staples Versus Conventional Skin Closure in Women Undergoing Cesarean Delivery

NCT05112640
Conditions
Operative Time, Wound Heal
Interventions
INSORB: subcuticular stapling device, Subcuticular monocryl suture manufactured by Ethicon
Device
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
117 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Galveston, Texas
Conditions
Malignant Gastric Outlet Obstruction
Interventions
EUS Gastrojejunostomy, Surgical Gastrojejunostomy, Gastric Outlet Obstruction Scoring System (GOOSS)
Procedure · Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Wound Infection, Wound Complication
Interventions
4-0 monofilament suture, Stainless steel staples
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
173 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Postoperative Complications, Obesity, Gynecologic Neoplasms
Interventions
Standard Wound Closure, Prevena™ Incision Management System
Procedure · Device
Lead sponsor
Masonic Cancer Center, University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Spinal Injuries
Interventions
Closure technique
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Rochester, Minnesota
Terminated Not applicable Interventional Accepts healthy volunteers

Postoperative Pain and Skin Closure Methods After Cesarean Section

NCT02028000
Conditions
Pregnancy
Interventions
Insorb staples skin closure, Monocryl skin closure, Vicryl skin closure
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Arthroplasty, Knee Replacement, Wound Healing
Interventions
Zip Surgical Skin Closure, Steel Staples
Device
Lead sponsor
ZipLine Medical Inc.
Industry
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Indianapolis, Indiana
Completed No phase listed Observational Accepts healthy volunteers

Use of Insorb Absorbable Vicryl Staples in Skin Closure for Cesarean Section

NCT01446627
Conditions
Wound Infection
Interventions
There is no intervention for this study
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
14 Years to 50 Years · Female only
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Houston, Texas