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ClinicalTrials.gov public records Last synced Oct 18, 2026, 8:41 AM EDT

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Showing 73–96 of 107 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Staples Clear all
Withdrawn Not applicable Interventional

A Randomized Controlled Trial Comparing Sutures vs Staples for High Tension Closures

NCT06638736
View directory record Official record
Conditions
Surgery, Skin Cancer, Suture; Complications, Infection or Inflammation
Interventions
Wound Closure with sutures vs staples
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Oct 18, 2026, 8:41 AM EDT
Terminated Not applicable Interventional Results available

Sleeve Gastrectomy Outcomes With Different Stapling Devices

NCT02731079
View directory record Official record
Conditions
Morbid Obesity
Interventions
Covidien iDrive, Ethicon Echilon
Device
Lead sponsor
Edna Rath
Federal
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Oct 18, 2026, 8:41 AM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Laparoscopic Sleeve Gastrectomy Plus Weight Watchers vs. Weight Watchers Alone in Underserved Minority Women

NCT01929850
View directory record Official record
Conditions
Morbid Obesity
Interventions
Laparscopic Sleeve Gastrectomy, Weight Watchers Program
Procedure · Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years · Female only
Healthy volunteers
Accepts healthy volunteers
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 8, 2015 · Synced Oct 18, 2026, 8:41 AM EDT
Terminated Not applicable Interventional Results available

Reinforced Staple Line on Leak Rate in Distal Pancreatectomy

NCT01359410
View directory record Official record
Conditions
Pancreatic Neoplasms
Interventions
Mesh reinforced staple line (SEAMGUARD), Stapled without mesh reinforcement (PER-STRIPS DRY)
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 10, 2017 · Synced Oct 18, 2026, 8:41 AM EDT
Terminated Not applicable Interventional Results available

Comparison Study of Wound Closure at Time of Cesarean Delivery: Dermabond Glue Versus Surgical Staples

NCT00524511
View directory record Official record
Conditions
Cesarean Section
Interventions
Surgical skin staples, Dermabond
Device
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
Female only
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 5, 2013 · Synced Oct 18, 2026, 8:41 AM EDT
Completed Not applicable Interventional Results available

Study of ECHELON ENDOPATH(TM) Staple Line Reinforcement

NCT04544865
View directory record Official record
Conditions
Gastric Procedures, Lung Resection Procedures
Interventions
Staple Line Reinforcement
Device
Lead sponsor
Ethicon Endo-Surgery
Industry
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
8
States / cities
Indianapolis, Indiana • Baton Rouge, Louisiana • Detroit, Michigan + 5 more
Source: ClinicalTrials.gov public record
Updated Dec 5, 2023 · Synced Oct 18, 2026, 8:41 AM EDT
Completed Not applicable Interventional Results available

NeoMend ProGEL™ Pleural Air Leak Sealant Post-Approval Study

NCT01394978
View directory record Official record
Conditions
Lung Cancer, Lung Tumor
Interventions
Control, ProGEL Pleural Air Leak Sealant with standard surgical closure, ProGEL Pleural Air Leak Sealant without standard surgical closure
Other · Device
Lead sponsor
C. R. Bard
Industry
Eligibility
18 Years and older
Enrollment
444 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
18
States / cities
Birmingham, Alabama • Jacksonville, Florida • Tampa, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Jul 15, 2021 · Synced Oct 18, 2026, 8:41 AM EDT
Not listed Phase 3 Interventional

Efficacy and Safety of LifeSeal™ Kit for Colorectal Staple Line Sealing

NCT02907385
View directory record Official record
Conditions
Rectal Cancer, Anastomotic Leak
Interventions
LifeSeal™ Kit
Device
Lead sponsor
LifeBond Ltd.
Industry
Eligibility
21 Years and older
Enrollment
736 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
23
States / cities
Los Angeles, California • Stanford, California • Florida City, Florida + 17 more
Source: ClinicalTrials.gov public record
Updated Mar 30, 2018 · Synced Oct 18, 2026, 8:41 AM EDT
Not listed Not applicable Interventional

Comparison of microMend® Devices to Sutures in Closing Lacerations in Children

NCT04557761
View directory record Official record
Conditions
Laceration, Skin Wound, Wound Heal
Interventions
microMend®, Closure with Sutures
Device
Lead sponsor
Children's Hospital of Orange County
Other
Eligibility
7 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Mar 28, 2022 · Synced Oct 18, 2026, 8:41 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Post-Operative Cesarean Section Cosmesis

NCT06412978
View directory record Official record
Conditions
Cesarean Delivery
Interventions
absorbable subcuticular polyglycolic acid staples (INSORB), subcuticular, polyglecaprone suture (Monocryl)
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Oct 18, 2026, 8:41 AM EDT
Completed Not applicable Interventional

Evaluation of the Impact of a Food is Medicine Program on Diabetes-related Health Outcomes for People With Type 2 Diabetes in a Low Income Community-based Setting Compared to Usual Care

NCT07529184
View directory record Official record
Conditions
Diabetes (DM)
Interventions
Food is medicine
Dietary Supplement
Lead sponsor
Public Health Institute Center for Wellness and Nutrition
Other
Eligibility
18 Years and older
Enrollment
405 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Stockton, California
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 18, 2026, 8:41 AM EDT
Completed Not applicable Interventional

ENTact™ Septal Stapler Shelf Life Extension

NCT00957502
View directory record Official record
Conditions
Deviated Nasal Septum
Interventions
ENTact™ Septal Stapler
Device
Lead sponsor
ENTrigue Surgical, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 23, 2012 · Synced Oct 18, 2026, 8:41 AM EDT
Completed Not applicable Interventional

Random Comparison of LigaSure and Disposable Staples for Laparoscopic Surgery

NCT00487409
View directory record Official record
Conditions
Colonic Diseases, Rectal Diseases
Interventions
Bipolar electrosurgical generator and instruments, Disposable stapling instruments
Procedure
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 15, 2014 · Synced Oct 18, 2026, 8:41 AM EDT
Recruiting Not applicable Interventional

The Medically Tailored Groceries and Mental Health Study

NCT07779707
View directory record Official record
Conditions
Depression / Major Depressive Disorder, Food Insecurity
Interventions
Medically Tailored, Home-delivered Groceries, Active Comparison Group: Monthly Grocery Gift Card
Other
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
3
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 18, 2026, 8:41 AM EDT
Terminated Not applicable Interventional Results available

Bioabsorbable Staple Line Reinforcement in Colorectal,Coloanal and Ileoanal Anastomoses

NCT00663819
View directory record Official record
Conditions
Rectal Cancer, Ulcerative Colitis, Familial Adenomatous Polyposis, Diverticulitis
Interventions
GORE SEAMGUARD® Bioabsorbable Staple Line Reinforcement, Staple line without reinforcement
Device · Procedure
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
18 Years and older
Enrollment
258 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
16
States / cities
Mobile, Alabama • Los Angeles, California • Weston, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Apr 17, 2018 · Synced Oct 18, 2026, 8:41 AM EDT
Completed Not applicable Interventional Results available

Study to Assess Perfusion and Patient Satisfaction in Nipple-Areola Mastectomy With Immediate Reconstruction

NCT01969448
View directory record Official record
Conditions
Ductal Carcinoma in Situ - Category, Breast Cancer, Prophylactic Mastectomy
Interventions
Inframammary Fold Incision or Lateral Radial Incision, Lateral Radial Incision, Inframammary Fold Incision, Laser-assisted fluorescence angiography, Indocyanine Green
Procedure · Device · Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 18, 2018 · Synced Oct 18, 2026, 8:41 AM EDT
Completed Phase 4 Interventional

Study of Sutures Versus Staples for Skin Closure After Surgical Procedures of Hip

NCT00273715
View directory record Official record
Conditions
Surgery
Interventions
Surgical wound closure techniques, Surgical wound closure techniques (Comparator)
Procedure
Lead sponsor
University of Kentucky
Other
Eligibility
18 Years and older
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 31, 2013 · Synced Oct 18, 2026, 8:41 AM EDT
Completed Phase 3 Interventional Results available

Safety and Efficacy the Medigus SRS Endoscopic Stapling System in Gastroesophageal Reflux Disease (GERD)

NCT00734747
View directory record Official record
Conditions
Gastroesophageal Reflux Disease (GERD)
Interventions
Medigus SRS endoscopic stapling system
Device
Lead sponsor
Aviel Roy-Shapira, M.D.
Industry
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
2
States / cities
San Diego, California • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 2, 2016 · Synced Oct 18, 2026, 8:41 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Endostapler Sleeve Gastrectomy Study

NCT04617574
View directory record Official record
Conditions
Obesity
Interventions
AEON Endostapler, Endo GIA Reloads with Tri-Staple Technology
Device
Lead sponsor
Lexington Medical Inc.
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Holyoke, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 22, 2021 · Synced Oct 18, 2026, 8:41 AM EDT
Not yet recruiting Not applicable Interventional

Health-Related Social Needs Food Boxes Delivery Program

NCT07643909
View directory record Official record
Conditions
Food Insecurity
Interventions
Monthly food staples and fresh produce, Standard of care
Other
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 18, 2026, 8:41 AM EDT
Completed Not applicable Interventional Results available

Negative Pressure Wound Therapy in Obese Gynecologic Oncology Patients

NCT02309944
View directory record Official record
Conditions
Postoperative Complications, Obesity, Gynecologic Neoplasms
Interventions
Standard Wound Closure, Prevena™ Incision Management System
Procedure · Device
Lead sponsor
Masonic Cancer Center, University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 27, 2020 · Synced Oct 18, 2026, 8:41 AM EDT
Completed Not applicable Interventional Results available

Comparison of Staples Versus Subcuticular Suture in Class III Obese Women Undergoing Cesarean Delivery

NCT02466776
View directory record Official record
Conditions
Obesity, Severe, Cesarean Section
Interventions
Absorbable subcuticular suture, Stainless steel staples
Device
Lead sponsor
MemorialCare Health System
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
238 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
4
States / cities
Long Beach, California • Orange, California
Source: ClinicalTrials.gov public record
Updated Jan 9, 2024 · Synced Oct 18, 2026, 8:41 AM EDT
Not listed Not applicable Interventional

A Study Comparing Two Different Techniques for Closing the Skin After a Cesarean Delivery

NCT00293683
View directory record Official record
Conditions
Cesarean Section
Interventions
Insorb absorbable skin staple
Device
Lead sponsor
Thomas Jefferson University
Other
Eligibility
12 Years to 55 Years · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 29, 2014 · Synced Oct 18, 2026, 8:41 AM EDT
Completed Phase 1Phase 2 Interventional

Evaluation of Safety and Efficacy of realSKIN® (Skin Xenotransplant) for Complete Closure of Severe Burn Wounds

NCT03695939
View directory record Official record
Conditions
Deep Full-thickness Burn Injury (Disorder)
Interventions
realSKIN (skin xenotransplant), Human Cadaver Allograft
Biological
Lead sponsor
XenoTherapeutics, Inc.
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
Augusta, Georgia • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 12, 2024 · Synced Oct 18, 2026, 8:41 AM EDT