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Showing 25–45 of 21 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Stepped care for depression Clear all
Completed Not applicable Interventional

Randomized Trial of Stepped Care for Suicide Prevention in Teens and Young Adults

NCT03092271
View directory record Official record
Conditions
Suicidal Behavior, Self-Harm, Deliberate, Suicidal Ideation, Suicide
Interventions
Stepped Care for Suicide Prevention, Zero Suicide Quality Improvement
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
12 Years to 24 Years
Enrollment
301 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
2
States / cities
Los Angeles, California • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 3, 2022 · Synced Sep 29, 2026, 5:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Stepped Care for Youth Living With HIV

NCT03109431
View directory record Official record
Conditions
HIV, Mental Health, Illicit Substance Use, Sexually Transmitted Infections (STI)
Interventions
Level 1, Level 2, Level 3
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
12 Years to 24 Years
Enrollment
170 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
2
States / cities
Los Angeles, California • New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Dec 5, 2022 · Synced Sep 29, 2026, 5:23 PM EDT
Completed Not applicable Interventional Results available

Stepped Telemental Health Care Intervention for Depression

NCT01906476
View directory record Official record
Conditions
Depression
Interventions
Stepped Care, Telephone Cognitive Behavior Therapy
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
312 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 7, 2023 · Synced Sep 29, 2026, 5:23 PM EDT
Enrolling by invitation Not applicable Interventional

Virtual Nurse and Social Worker Palliative Care Team to Improve Quality of Life in Veterans With Heart Failure or COPD

NCT07714252
View directory record Official record
Conditions
Heart Failure, Pulmonary Disease, Chronic Obstructive, Interstitial Lung Disease
Interventions
Virtual Nurse and Social Worker Palliative Care Team, Enhanced Implementation Support, Standard Implementation Support
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
7
States / cities
Phoenix, Arizona • Long Beach, California • Aurora, Colorado + 4 more
Source: ClinicalTrials.gov public record
Updated Aug 23, 2026 · Synced Sep 29, 2026, 5:23 PM EDT
Completed Phase 2Phase 3 Interventional

A Stepped Care Model of Adolescent Depression Treatment in Primary Care

NCT01443715
View directory record Official record
Conditions
Major Depressive Disorder, Dysthymia
Interventions
Stepped Care IPT-A (SCIPT-A), Treatment as Usual
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
13 Years to 20 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 3, 2014 · Synced Sep 29, 2026, 5:23 PM EDT
Completed Not applicable Interventional Results available

COPES Phase I Randomized Controlled Trial of Treatment For Distress in Heart Disease Patients

NCT00158054
View directory record Official record
Conditions
Heart Diseases, Depression
Interventions
Enhanced depression care, Referred depression care
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
21 Years and older
Enrollment
157 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2015
U.S. locations
3
States / cities
New Haven, Connecticut • New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 22, 2017 · Synced Sep 29, 2026, 5:23 PM EDT
Completed Not applicable Interventional

Pepped on Pre-exposure Prophylaxis (PrEP): A Counseling and Problem-Solving PrEP Adherence Intervention for Stimulant Using Men Who Have Sex With Men (MSM).

NCT03137342
View directory record Official record
Conditions
PrEP Uptake, Stimulant Abuse, Adherence, Medication
Interventions
Pepped on PrEP Package
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older · Male only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 10, 2018 · Synced Sep 29, 2026, 5:23 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Digitally Enhanced Stepped-Care for Depression in Primary Care

NCT07634705
View directory record Official record
Conditions
Depression
Interventions
Behavioral Activation Therapy App, Telehealth Delivered Behavioral Activation
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 29, 2026, 5:23 PM EDT
Completed Not applicable Interventional Results available

Stepped Care for Depression in Heart Failure

NCT02997865
View directory record Official record
Conditions
Heart Failure, Depressive Disorder, Major
Interventions
Stepped care for depression
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
25 Years and older
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 9, 2023 · Synced Sep 29, 2026, 5:23 PM EDT
Withdrawn Not applicable Interventional

Intervention for Rural Cancer Patients

NCT05091593
View directory record Official record
Conditions
Depression, Quality of Life, Social Support, Sleep, Stress
Interventions
Stepped collaborative care intervention, Enhanced Usual Care
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
21 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 27, 2025 · Synced Sep 29, 2026, 5:23 PM EDT
Completed Not applicable Interventional Results available

Trauma Survivors Outcomes and Support Study IV

NCT01625416
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Depression, Suicide, Traumatic Brain Injury, Alcohol Use, Drug Use
Interventions
Stepped Care Management
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
14 Years and older
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 12, 2017 · Synced Sep 29, 2026, 5:23 PM EDT
Completed Phase 2 Interventional Results available

eIMPACT-DM Pilot Trial: Depression Treatment to Reduce Diabetes Risk

NCT04437485
View directory record Official record
Conditions
Depression, Major Depressive Disorder, Dysthymic Disorder, Depressive Symptoms, Type 2 Diabetes, PreDiabetes, Insulin Resistance
Interventions
Good Days Ahead (GDA), Problem Solving Treatment in Primary Care (PST-PC), Antidepressant Medications, Active Control
Behavioral · Drug · Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 1, 2023 · Synced Sep 29, 2026, 5:23 PM EDT
Completed Not applicable Interventional

Managed Problem Solving for ART Adherence and HIV Care Retention Delivered by Community Health Workers

NCT04560621
View directory record Official record
Conditions
HIV/AIDS
Interventions
Managed Problem Solving (MAPS)
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
10
States / cities
Camden, New Jersey • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 2, 2025 · Synced Sep 29, 2026, 5:23 PM EDT
Completed Not applicable Interventional Results available

Reaching and Engaging Depressed Senior Center Clients (REDS)

NCT03246789
View directory record Official record
Conditions
Depression, Unipolar, Mental Health Disorder
Interventions
Engage-M, Wellness in Mind and Body
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
55 Years to 100 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 18, 2022 · Synced Sep 29, 2026, 5:23 PM EDT
Recruiting Not applicable Interventional

Latinas Integrating Fitness and Therapy

NCT07223346
View directory record Official record
Conditions
Stepped Care Cognitive Behavioral Therapy, Exercise, Physical Activity, Anxiety Depression
Interventions
Stepped Care Mental Health Counseling, Exercise Program
Behavioral
Lead sponsor
Colorado State University
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Sep 29, 2026, 5:23 PM EDT
Completed Not applicable Interventional Results available

PRogram In Support of Moms: An Innovative Stepped-Care Approach for Obstetrics and Gynecology Clinics

NCT02760004
View directory record Official record
Conditions
Depression
Interventions
PRogram In Support of Moms (PRISM), MCPAP for Moms
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
312 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 9, 2024 · Synced Sep 29, 2026, 5:23 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Improving Adult Protective Services Client Outcomes: A Stepped-Care Social and Mental Health Engagement Program

NCT06257095
View directory record Official record
Conditions
Depression in Old Age
Interventions
Stepped-care social and mental health engagement, APS Usual care
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
65 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Sep 29, 2026, 5:23 PM EDT
Completed Not applicable Interventional Results available

Hepatitis C Translating Initiatives for Depression Into Effective Solutions

NCT01143896
View directory record Official record
Conditions
Hepatitis C, Depression
Interventions
Depression collaborative care model
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 99 Years
Enrollment
309 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
4
States / cities
Little Rock, Arkansas • West Los Angeles, California • St Louis, Missouri + 1 more
Source: ClinicalTrials.gov public record
Updated May 15, 2016 · Synced Sep 29, 2026, 5:23 PM EDT
Completed Not applicable Interventional Results available

Treating Depression Among Low-Income Patients With Cancer

NCT00565110
View directory record Official record
Conditions
Major Depression, Dysthymia
Interventions
ADAPt-C intervention
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
472 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 23, 2017 · Synced Sep 29, 2026, 5:23 PM EDT
Completed Not applicable Interventional

Collaborative Care Model for the Treatment of Persistent Symptoms After Concussion Among Youth

NCT03034720
View directory record Official record
Conditions
Concussion, Brain, TBI, Depression, Anxiety
Interventions
Collaborative Care
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
11 Years to 18 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 7, 2021 · Synced Sep 29, 2026, 5:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reaching Out to Adolescents With Depression

NCT01140464
View directory record Official record
Conditions
Depression
Interventions
Collaborative care, Enhanced Usual Care
Other
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
13 Years to 17 Years
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 30, 2017 · Synced Sep 29, 2026, 5:23 PM EDT