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Conditions: Rett Syndrome
Interventions: Electroencephalogram (EEG) Recording; Procedure
Lead sponsor: University of Rochester; Other
Eligibility: 2 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Depression, Ketosis
Interventions: Ketogenic Diet, NIH Toolbox, gradCPT, Resting-state fMRI, Task-fMRI, CGM/CKM, Blood Draw, Sleep Monitoring, Ketone/Glucose Monitoring, Body Composition, PHQ-9, WHO-5, SKID; Other · Biological · Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years to 30 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Acute Lymphoblastic Leukemia, Transcranial Direct Current Stimulation, Executive Dysfunction
Interventions: Anodal tDCS treatment, Cathodal tDCS treatment, Sham treatment, NIH Toolbox List Sorting Working Memory Test, NIH Toolbox Flanker Inhibitory Control and Attention Test, Grooved Peg Board Test, Buschke Selective Reminding Test; Device · Other
Lead sponsor: St. Jude Children's Research Hospital; Other
Eligibility: 8 Years to 215 Months
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Basic Science: Visual Attention in Healthy Participants, Basic Science: Neural Representations of Location
Interventions: Stimulus properties: remembered feature; Other
Lead sponsor: University of California, Santa Barbara; Other
Eligibility: 18 Years to 55 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Santa Barbara, California

Conditions: Memory Consolidation
Interventions: Congruent vs. Incongruent, Immediate vs. Awake vs. Asleep, Targeted memory reactivation (TMR); Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 35 Years
Enrollment: 194 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Self-Injurious Behavior, Suicidal Ideation, Suicide Attempts
Interventions: Therapeutic Evaluative Conditioning, Neutral comparison condition; Behavioral
Lead sponsor: Franciscan Hospital For Children, INC.; Other
Eligibility: 12 Years to 19 Years
Enrollment: 155 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Brighton, Massachusetts

Conditions: Gastric Bypass Surgery Pain Management
Interventions: Real TMS 45 min, Sham TMS 45 min, Real TMS 4 Hours, Sham TMS 4 Hours; Device
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 60 Years
Enrollment: 108 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2011
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Breast Cancer, Cognitive Change, Cognitive Impairment, Quality of Life
Interventions: Sweep Seeker, Bird Safari, Jewel Diver, Master Gardener, Road Tour, Computerized Crossword Puzzles; Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 21 Years and older · Female only
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Self-Injurious Behavior, Problem Behavior, Intellectual Disability, Autism Spectrum Disorder, Restricted Behavior
Interventions: AUTOSIB across time, AUTOSIB diminished reinforcement; Behavioral
Lead sponsor: University of Georgia; Other
Eligibility: 2 Years and older
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Randolph, Massachusetts

Conditions: Parkinson's Disease
Interventions: Capsaicin vapor, fog, Videofluoroscopic swallow evaluation, Nebulizer; Drug · Other · Radiation + 1 more
Lead sponsor: University of Florida; Other
Eligibility: 50 Years to 80 Years
Enrollment: 158 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Episodic Memory
Interventions: Visual Memory Encoding and Retrieval Task During fMRI; Behavioral
Lead sponsor: Brown University; Other
Eligibility: 18 Years to 40 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Glaucoma, Suspect
Interventions: Pattern Electroretinogram; Diagnostic Test
Lead sponsor: Jorvec Corp.; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Autism Spectrum Disorder
Interventions: Stimulus-stimulus pairing, Vocal recorder; Behavioral · Other
Lead sponsor: Emory University; Other
Eligibility: 24 Months to 47 Months
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Opioid Use Disorder, Substance Use Disorder, Heroin Use Disorder
Interventions: Real-time fMRI Neurofeedback, Sham Real-time fMRI Neurofeedback; Behavioral
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years to 64 Years
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: New York, New York

Conditions: Depression
Interventions: Traditional Attention Bias Modification, Gamified Attention Bias Modification, Sham Attention Bias Modification; Behavioral
Lead sponsor: University of Texas at Austin; Other
Eligibility: 18 Years to 70 Years
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Obsessive Compulsive Disorder
Interventions: CBT treatment for OCD based on Exposure & Response Prevention (EX/RP) and when indicated medication treatment; Behavioral
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 5 Years to 17 Years
Enrollment: 55 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2021
U.S. locations: 1
States / cities: New York, New York

Conditions: Fibrous Dysplasia/McCune-Albright Syndrome
Interventions: MRI-based Neuroimaging, Non-contrast MRI, 18F-FDG-PET/CT, 18F-NaF-PET/CT; Diagnostic Test
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 10 Years to 45 Years
Enrollment: 37 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Post Traumatic Stress Disorder
Interventions: Experiment 1. Three-day aversive conditioning, extinction, and extinction retention testing paradigm, Allopregnanolone (Allo) with 6% USP Dexolve (sulfobutyl ether-beta-cyclodextrin sodium salt) in 0.9% saline for IV infusion will be provided by the University of California, Davis, GMP manufacturer., Matching IV Placebo, Experiment 2. Three-day aversive conditioning, reconsolidation blockade, and testing paradigm; Behavioral · Drug · Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 55 Years
Enrollment: 96 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Gait Disorders, Neurologic
Interventions: Fractal visual cueing, Periodic visual cueing, Random visual cueing; Behavioral
Lead sponsor: University of Nebraska; Other
Eligibility: 65 Years to 90 Years
Enrollment: 1 participant
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: Multiple Sclerosis, Cognitive Deficits, Gilenya Modifying Therapy for MS
Interventions: plasticity-based computerized cognitive remediation program, Gileyna; Other · Drug
Lead sponsor: Stony Brook University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Stony Brook, New York

Conditions: Healthy
Interventions: Cold-Pressor Task (CPT), Control CPT, fMRI; Behavioral · Device
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 64 Years
Enrollment: 397 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: New York, New York

Conditions: Healthy Adults, Mechanical Ventilation Dependence, Hypoxia, Exercise Training, Exercise Intolerance, Dietary Supplement, Nitrate Supplementation, Inspiratory Muscle Training
Interventions: Respiratory Muscle Training (RMT), Sham Respiratory Muscle Training, Dietary Supplement: Beetroot Juice Concentrate, placebo beverage; Device · Dietary Supplement
Lead sponsor: Embry-Riddle Aeronautical University; Other
Eligibility: 18 Years to 40 Years
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Daytona Beach, Florida

Conditions: Smoking
Interventions: Augmented Reality 1, Augmented Reality 2, Augmented Reality 3, Augmented Reality 4; Behavioral
Lead sponsor: H. Lee Moffitt Cancer Center and Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 197 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Migraine, Vestibular Migraine, Vestibular Schwannoma, Motion Sickness, Dizziness, Vestibular Disorder
Interventions: Temporal Binding Adaptation - PSS training, Temporal Binding Adaptation - PSS adaptation with VI stimulation, Chronic Motion-modulated Stimulation; Behavioral
Lead sponsor: Massachusetts Eye and Ear Infirmary; Other
Eligibility: 8 Years to 80 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2025
U.S. locations: 1
States / cities: Boston, Massachusetts

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Auditory EEG and Behavioral Assessments in Individuals With Rett Syndrome

Ketogenic Intervention in Depression

Transcranial Direct Current Stimulation of the Temporal Cortex in Survivors of Childhood Acute Lymphoblastic Leukemia (ALL)

Probing the Role of Feature Dimension Maps in Visual Cognition: Impact of Working Memory Maintenance (Expt 2.3)

The Impact of Reactivation During Sleep on the Consolidation of Abstract Information in Humans

Therapeutic Evaluative Conditioning to Reduce Adolescents' Self-injurious Thoughts and Behaviors During and After Psychiatric Inpatient Hospitalization

Transcranial Magnetic Stimulation Effects on Pain Perception

Computerized Cognitive Training in Breast Cancer Survivors

Expanding Interventions for Automatically Maintained SIB

Cough According to Stimulus Type in PD

The Dynamics of Representational Change Underlying Recall

CLAD Deconvolved PERG Responses in Glaucoma Patients

Stimulus-Stimulus Pairing Study

Neurofeedback During Naturalistic Stimuli to Reduce Craving in Heroin Addiction

Confirmatory Efficacy Trial of Attention Bias Modification for Depression

Overlapping Neural Circuits in Pediatric OCD

Pain in Fibrous Dysplasia

Facilitation of Extinction Retention and Reconsolidation Blockade by IV Allopregnanolone in PTSD.

Variable Visual Stimulus as a Novel Approach for Gait Rehabilitation

Computerized Exercise Training for Cognitive Remediation in Adults With Multiple Sclerosis Treated With Gilenya

Neural Mechanisms of Cost and Benefit Integration During Decision-Making, Aim 2: Acute & Lifetime Stress

Effects of Breathing Training and Nitrate on Exercise at Simulated Altitude

Utilizing Augmented Reality as an Adjunct for Smoking Cessation

Analysis of Vestibular Compensation Following Clinical Intervention for Vestibular Schwannoma