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Conditions: Musculoskeletal Diseases
Interventions: Story checklist; Other
Lead sponsor: University of Texas at Austin; Other
Eligibility: 18 Years to 89 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 5
States / cities: Austin, Texas

Conditions: Traumatic Brain Injury
Interventions: Rehabilitation Discharge Plan, Rehabilitation Transition Plan; Other
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 1,555 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 6
States / cities: Indianapolis, Indiana • New York, New York • Columbus, Ohio + 3 more

Conditions: Pediatric Asthma
Interventions: CASE in person version (High Intensity Package), CASE-V remote version (Low Intensity Package), CASE and HARP in person (High Intensity package), CASE-V and HARP-V remote version (Low Intensity package); Behavioral
Lead sponsor: Rhode Island Hospital; Other
Eligibility: 2 Years to 12 Years
Enrollment: 480 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Fatigue, Depression, Pain, Sleep Disturbance, Stress, Survivorship, Breast Cancer, Dietary Habits
Interventions: Personalized Meal Plan, Dietary Omega-3LC intervention; Behavioral
Lead sponsor: University of Connecticut; Other
Eligibility: 35 Years to 70 Years · Female only
Enrollment: 98 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Hartford, Connecticut

Conditions: Sensory Disorders, Autism, Autism Spectrum Disorder, Autism With High Cognitive Abilities, Autistic Behavior, Hyperacusis
Interventions: Exposure therapy, Psycho-education, Caregiver education/home program development; Behavioral
Lead sponsor: University of Florida; Other
Eligibility: 5 Years to 17 Years
Enrollment: 5 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 2
States / cities: Gainesville, Florida

Conditions: Death, Postoperative Complications, Myocardial Infarction, Stroke, Renal Failure
Interventions: FACE quality improvement initiative (see below), Pre-quality improvement initiative; Other
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 2
States / cities: Ann Arbor, Michigan • St Louis, Missouri

Conditions: Other Specified Complications of Labor and Delivery
Interventions: Vaginal Delivery Debrief Checklist; Other
Lead sponsor: Providence Health & Services; Other
Eligibility: Not listed
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013
U.S. locations: 1
States / cities: Olympia, Washington

Conditions: Musculoskeletal Injury Trauma
Interventions: Integrated care (ICare), Usual Care (UsCare), Patient-Reported Outcomes Measurement Information System, Lower Extremity Gain Scale (LEGS), Dynamometer, Active Range of Motion (AROM), Posttraumatic Stress Disorder (PTSD), Beck Depression Inventory-II, State-Trait Anxiety Inventory (STAI), Tampa Scale of Kinesiophobia-11 (TSK-11); Procedure · Other
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 85 Years
Enrollment: 88 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2023
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Sepsis Severe, Septic Shock
Interventions: Sepsis Bundle; Other
Lead sponsor: Rhode Island Hospital; Other
Eligibility: 18 Years and older
Enrollment: 10,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Tourette Syndrome
Interventions: The Sensory Profile, The Adult/Adolescent Sensory Profile, Children's Yale-Brown Obsessive Compulsive Scale, Yale-Brown Obsessive Compulsive Scale, Yale Global Tic Severity Scale, Demographic Data; Other
Lead sponsor: University of Florida; Other
Eligibility: 6 Years to 18 Years
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Fall, Accidental, Fall, Hospital Readmission, Emergency Medical Services
Interventions: Transport PLUS group; Behavioral
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older
Enrollment: 58 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: COPD
Interventions: Education (self-guided), Education (counselor-led), Physical Activity, Inhaler Training; Behavioral
Lead sponsor: Rush University Medical Center; Other
Eligibility: 40 Years and older
Enrollment: 448 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Children, Only, Risk Reduction, Environmental Exposure
Interventions: Changes in pesticide exposure, IPM Practices, Educational Workshops; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 3 Years to 75 Years
Enrollment: 987 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2024
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Autism Spectrum Disorder, Autism
Interventions: Early Diagnostic Response Model Expanded; Behavioral
Lead sponsor: Emory University; Other
Eligibility: 16 Months to 36 Months
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Hospice, Pain, Anxiety, Stress
Interventions: Reiki therapy; Other
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Critical Illness
Interventions: Live music, Recorded music, Usual care; Behavioral · Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 2 Months to 17 Years
Enrollment: 171 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Post Operative Complications, Pneumonia
Interventions: ICOUGH Recovery App v2.0; Other
Lead sponsor: Boston Medical Center; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Substance Use
Interventions: Standard Screening, Standard Psychoeducation, Standard Brief Negotiated Interview (BNI), Standard Referral to Treatment (RT), Family Screening, Family Psychoeducation, Family Brief Negotiated Interview (BNI), Family Facilitated Conversation (FC) & Referral to Treatment (RT); Behavioral
Lead sponsor: The National Center on Addiction and Substance Abuse at Columbia University; Other
Eligibility: 12 Years to 17 Years
Enrollment: 2,300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2029
U.S. locations: 1
States / cities: New York, New York

Conditions: Hematological Malignancy
Interventions: Body Scan, Rotterdam Symptom Checklist, Practice Logs; Behavioral · Other
Lead sponsor: Washington University School of Medicine; Other
Eligibility: Not listed
Enrollment: 37 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Critical Illness, Hypoxia, Respiratory Failure
Interventions: End-tidal oxygen monitor; Device
Lead sponsor: Sydney Local Health District; Government
Eligibility: 18 Years and older
Enrollment: 1,400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 3
States / cities: Minneapolis, Minnesota • Albuquerque, New Mexico • The Bronx, New York

Conditions: COVID-19, Proning, Oxygenation, Length of Stay
Interventions: Proning group, Control group; Other
Lead sponsor: Baylor St. Luke's Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 216 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Low Back Pain, Neck Pain
Interventions: Engagement of clinic leadership (System Intervention - Usual Care), Engagement of clinic leadership (System Intervention - STEPPT), Patient Registry (System Intervention - STEPPT), Delivery of Patient Education Materials (System Intervention - Usual Care), Delivery of Patient Education Materials (System Intervention - STEPPT), Referral Specialist Training (System Intervention - Usual Care), Patient Health Navigator Training (System Intervention - STEPPT), Care Navigation (System Intervention - STEPPT), Care navigation audit and feedback (System Intervention - STEPPT), Primary Care Provider training (Provider Intervention - STEPPT), Nurse/Medical Assistant Training (Provider Intervention - STEPPT), Provider feedback on PT referral and adherence (Provider Intervention - STEPPT), Patient education on spine pain condition (Patient Intervention - Usual Care), Patient education on spine pain condition (Patient Intervention - STEPPT), Patient Education on Physical Referral by Providers (Patient Intervention - Usual Care), Patient Education on Physical Referral by Providers (Patient Intervention - STEPPT), Electronic Patient Education on Physical Therapy Referral (Patient Intervention - STEPPT), Patient education on physical therapy referral by Referral Specialist (Patient Intervention - Usual Care), Patient education on physical therapy referral by Patient Health Navigator (Patient Intervention - STEPPT), Care Navigation (System Intervention - Usual Care), Monitoring of PT referral and adherence rates (System Intervention - STEPPT), Monitoring of PT referral and adherence rates (System intervention - Usual Care); Behavioral
Lead sponsor: San Diego State University; Other
Eligibility: 18 Years and older
Enrollment: 17,587 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: San Diego, California

Conditions: Concussion, Brain
Interventions: Active Rehab (Group 2), Progressive Return to Activity (Group 1); Other
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 99 Years
Enrollment: 130 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 2
States / cities: Fort Liberty, North Carolina

Conditions: Amputation, Prosthesis Use
Interventions: Training with PRC, Training with DC, PRC Device use in community and home, DC Device use in community and home; Device
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years and older
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 2
States / cities: Austin, Texas • Richmond, Virginia

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Disjunction Between Patient Narrative and Formulaic Thinking in the Doctor

Brain Injury Rehabilitation Improving the Transition Experience

The Puerto Rico Asthma Integrated Response Program ("PR-AIR")

Adaptive Symptom Care Using Fish-Based Nutritional Directives Post Breast Cancer

Exposure Therapy for Auditory Sensitivity in Autism

Study to Determine the Impact of Intraoperative Blood Pressure Management on Postoperative Outcomes (MAP-ALIVE)

Vaginal Delivery Debrief Checklist to Improve Team Communication

An Integrated-Delivery-of-Care Approach to Improve Patient Outcomes, Safety, Well-Being After Orthopaedic Trauma

Assessment for Implementation Methods in Sepsis

Sensory Processing in Tourette Syndrome

Transport PLUS Intervention

COPD Resources, Education, and Activity Designed for You Study

Reducing Pesticide Exposures in Child Care Centers

Early Diagnostic Telehealth Pilot for Moderate- and High-Risk Children: Evaluating Assessment Protocols and Efficiency in Georgia's Early Intervention Program

Teaching Caregivers of Hospice Patients to Administer Reiki

Music Listening: A Mechanistic Trial

Inpatient ICOUGH RECOVERY App Version 2.0

Primary Connections for Youth and Families

Body Scan Activity on Bone Marrow Transplant Patients and Their Caregivers

End-Tidal Oxygen for Intubation in the Emergency Department

Non-ventilated Prone Positioning in the COVID-19 Population

Stratified Targeted Engagement From Primary Care to Physical Therapy (STEPPT)

A Pragmatic Rehabilitation Intervention: The Active Rehab Study

Comparing the Attentional Demands and Functional Outcomes in People With Transradial Amputation