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ClinicalTrials.gov public records Last synced Nov 9, 2026, 12:05 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 145 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Stress Challenge Clear all

Conditions: Post Traumatic Stress Disorder
Interventions: CPT Skills, Cognitive Processing Therapy, Present Centered Therapy, Shared Decision Making, Measurement Based Care; Behavioral
Lead sponsor: United States Department of Defense; Federal
Eligibility: 18 Years and older
Enrollment: 280 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 4
States / cities: Phoenix, Arizona • New Orleans, Louisiana • Charleston, South Carolina + 1 more

Conditions: Dementia, Alzheimer Disease
Interventions: Telephone Support; Behavioral
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 21 Years and older
Enrollment: 154 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2014
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Dementia
Interventions: Tailored Activity Program, Home Safety and Education Program; Behavioral · Other
Lead sponsor: Johns Hopkins University; Other
Eligibility: 21 Years and older
Enrollment: 250 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Compassion Fatigue
Interventions: Mindfulness-Based Stress Reduction (MBSR) Program; Behavioral
Lead sponsor: Nova Southeastern University; Other
Eligibility: 18 Years and older
Enrollment: 11 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Hollywood, Florida

Conditions: Sensory Disorders, Autism, Autism Spectrum Disorder, Autism With High Cognitive Abilities, Autistic Behavior, Hyperacusis
Interventions: Exposure therapy, Psycho-education, Caregiver education/home program development; Behavioral
Lead sponsor: University of Florida; Other
Eligibility: 5 Years to 17 Years
Enrollment: 5 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 2
States / cities: Gainesville, Florida

Conditions: Pediatric Brain Tumor
Interventions: Survivor's Journey+; Behavioral
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 15 Years to 25 Years
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 2
States / cities: Cincinnati, Ohio • Columbus, Ohio

Conditions: Reading Problem
Interventions: Reading, Mindset, Reading Embedded with Mindset, Business as Usual; Behavioral
Lead sponsor: Vanderbilt University; Other
Eligibility: 9 Years to 11 Years
Enrollment: 580 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 2
States / cities: Nashville, Tennessee • Dallas, Texas

Conditions: Depression, Stress Disorders, Post-traumatic, Bipolar Disorder
Interventions: Treatment As Usual, Cornerstone; Behavioral
Lead sponsor: New York University; Other
Eligibility: 17 Years to 18 Years
Enrollment: 59 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: New York, New York

Conditions: Stress Disorders, Post-Traumatic, Depressive Symptoms, Anxiety Symptoms, Quality of Life
Interventions: Cognitive Processing Therapy, Present-Centered Therapy; Behavioral
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years and older
Enrollment: 129 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Autism Spectrum Disorder
Interventions: Strengthening Skills Program, PEERS Social Skills Program; Behavioral
Lead sponsor: Southwest Autism Research & Resource Center; Other
Eligibility: 21 Years to 70 Years
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Tempe, Arizona

Conditions: Hematopoietic/Lymphoid Cancer
Interventions: fPER; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 85 Years
Enrollment: 159 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2017
U.S. locations: 2
States / cities: Aurora, Colorado • Denver, Colorado

Conditions: Care Giving Burden, Dementia, Chronic Pain, Pain Management, Palliative Care
Interventions: Web-based pain management support tool, Usual Pain Management Care; Other · Behavioral
Lead sponsor: University of Iowa; Other
Eligibility: 18 Years to 100 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: PTSD, Concussion, Mild
Interventions: SMART-CPT, CPT; Behavioral
Lead sponsor: San Diego Veterans Healthcare System; Federal
Eligibility: 18 Years to 55 Years
Enrollment: 124 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: San Diego, California

Conditions: Physiological Stress
Interventions: Not listed
Lead sponsor: Texas State University; Other
Eligibility: 18 Years to 39 Years
Enrollment: 56 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: San Marcos, Texas

Conditions: Cervical Pain
Interventions: Yoga Group Exercise, Pilates Group Mat Exercise; Other
Lead sponsor: Wayne State University; Other
Eligibility: 18 Years and older
Enrollment: 88 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 4
States / cities: Bloomfield Hills, Michigan • Detroit, Michigan • Novi, Michigan + 1 more

Conditions: Breast Cancer Female
Interventions: The Behavioral Activation/ Problem Solving Intervention, Attention Control Condition; Behavioral
Lead sponsor: MGH Institute of Health Professions; Other
Eligibility: 18 Years and older · Female only
Enrollment: 303 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 2
States / cities: Birmingham, Alabama • Lebanon, New Hampshire

Conditions: PTSD
Interventions: Renew; Behavioral
Lead sponsor: Palo Alto Veterans Institute for Research; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Menlo Park, California

Conditions: Stress, Mental Health Wellness 1
Interventions: HeartBot App; Behavioral
Lead sponsor: Ranjani Iyer; Other
Eligibility: 14 Years and older
Enrollment: 88 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Novi, Michigan

Conditions: Postural Orthostatic Tachycardia Syndrome, Postural Tachycardia Syndrome, Tachycardia, Arrhythmias, Cardiac, Autonomic Nervous System Diseases, Orthostatic Intolerance, Cardiovascular Diseases, Primary Dysautonomias
Interventions: phenylephrine, isoproterenol, 25 micro-Ci of radiation, Posture study with blood samples, 24-hour heart rhythm and blood pressure monitoring, Quantitative Axonal Sudomotor Reflex Testing, Autonomic function tests, Rebreathing test, Assessment of splanchnic capacitance, microneurography; Drug · Radiation · Procedure + 1 more
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years to 50 Years
Enrollment: 58 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2026
U.S. locations: 2
States / cities: Oklahoma City, Oklahoma • Nashville, Tennessee

Conditions: Body Dysmorphic Disorder, Obsessive-Compulsive Spectrum Disorder, Anxiety Disorders, Somatoform Disorders
Interventions: Cognitive Behavioral Therapy, Supportive Psychotherapy; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2017
U.S. locations: 2
States / cities: Boston, Massachusetts • Providence, Rhode Island

Conditions: Parent-Child Relations
Interventions: Family Foundations Coparenting Program; Behavioral
Lead sponsor: Penn State University; Other
Eligibility: 18 Years and older
Enrollment: 497 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2002 – 2007
U.S. locations: 1
States / cities: University Park, Pennsylvania

Conditions: Aggression, Anger, Posttraumatic Stress Disorder
Interventions: Cognitive Behavioral Therapy, Present Centered Therapy; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Healthcare Professionals
Interventions: Narrative Medicine Workshop; Behavioral
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 21 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Post Traumatic Stress Disorder
Interventions: Repetitive Transcranial Magnetic Stimulation (rTMS), Cognitive Processing Therapy, Repetitive Transcranial Magnet Stimulation (rTMS); Device · Behavioral
Lead sponsor: The University of Texas at Dallas; Other
Eligibility: 18 Years to 60 Years
Enrollment: 103 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Dallas, Texas

Search by objective public record fields.

Reducing Dropout and Improving Outcomes From PTSD Therapy: When to Switch Therapies or Stay the Course

Testing the Effectiveness of Telephone Support for Dementia Caregivers

Reducing Agitation in People With Dementia: the Customized Activity Trial

MBSR Programs to Reduce Compassion Fatigue in Nurses

Exposure Therapy for Auditory Sensitivity in Autism

Survivors Journey+

Improving Response to Intervention in Students With or at Risk of Reading Disabilities

Cornerstone Program for Transition-Age Youth Study Protocol for a Randomized Controlled Trial

Treatment for Veterans With Military Sexual Trauma

Strengthening Skills Behavioral Intervention for Adults With Autism Spectrum Disorder

Improved Outcome in Allogeneic Hematopoietic Stem Cell Transplant (HSCT) Patients by Reducing Caregiver Distress

E-Tailored Pain Management Support for Dementia Family Caregivers: Feasibility of the PACE-app

SMART-CPT for PTSD/Concussion Implementation

Impact of Combined Stress on Biomarkers of Stress

Effect of Group Pilates and Yoga Exercise Classes for Chronic Cervical Pain

Optimizing Functional Recovery of Breast Cancer Survivors

Testing a Self-Management App for Symptoms of Posttraumatic Stress

The Effects of the App HeartBot on the Stress and Emotional Well-Being Over a 21-day Challenge

Autoimmune Basis for Postural Tachycardia Syndrome

Cognitive-Behavioral Therapy and Supportive Psychotherapy for Body Dysmorphic Disorder

Family Foundations Coparenting Pilot Trial

Group CBT for Aggression in Veterans

Narrative Medicine Effects on Burnout and Stress

Novel Treatment of Emotional Dysfunction in Post Traumatic Stress Disorder (PTSD)