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ClinicalTrials.gov public records Last synced Nov 11, 2026, 10:40 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 97–120 of 145 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Stress Challenge Clear all

Conditions: Weight Loss Trial, Cardiometabolic Syndrome, Hypertension, Dyslipidemia, Pre-diabetes, Type 2 Diabetes Mellitus
Interventions: Partnership for Improving Lifestyle Intervention (PILI) Lifestyle Program + Social Determinants of Health (SDOH) Component; Behavioral
Lead sponsor: University of Hawaii; Other
Eligibility: 18 Years and older
Enrollment: 242 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 4
States / cities: Fayetteville, Arkansas • Springdale, Arkansas • Honolulu, Hawaii

Conditions: Stress Disorders, Post-Traumatic
Interventions: Adjunctive writing to amplify response and engagement (AWARE), Cognitive processing therapy (CPT), Prolonged exposure (PE); Behavioral
Lead sponsor: Boston University; Other
Eligibility: 18 Years and older
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Sensory Disorders, Autism, Autism Spectrum Disorder, Autism With High Cognitive Abilities, Autistic Behavior, Hyperacusis
Interventions: Exposure therapy, Psycho-education, Caregiver education/home program development; Behavioral
Lead sponsor: University of Florida; Other
Eligibility: 5 Years to 17 Years
Enrollment: 5 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 2
States / cities: Gainesville, Florida

Conditions: Skin Health
Interventions: Supportive care with OCT product; Other
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Bone Marrow Transplant Complications
Interventions: BMT-VR; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: PTSD - Post Traumatic Stress Disorder, Depression/Anxiety
Interventions: Mobile Health Stress Self Management System, Intensive Cycling Activity; Behavioral
Lead sponsor: Texas A&M University; Other
Eligibility: 18 Years and older
Enrollment: 37 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: College Station, Texas

Conditions: Healthy Diet, Stress, Pediatric Obesity, Intergenerational Relations
Interventions: Happy Family, Healthy Kids Program; Behavioral
Lead sponsor: Michigan State University; Other
Eligibility: 3 Years to 5 Years
Enrollment: 214 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Thompsonville, Michigan

Conditions: Hot Flashes, Stress
Interventions: Mindfulness-based stress reduction; Behavioral
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 40 Years to 69 Years · Female only
Enrollment: 110 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2012
U.S. locations: 1
States / cities: Worcester, Massachusetts

Conditions: Anxiety
Interventions: Brief Cognitive Behavioral Therapy; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 225 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 3
States / cities: New Orleans, Louisiana • Houston, Texas • San Antonio, Texas

Conditions: Heart Failure
Interventions: Care-HF; Behavioral
Lead sponsor: Florida State University; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 4
States / cities: Gainesville, Florida • Togus, Maine • Durham, North Carolina + 1 more

Conditions: Breast Cancer
Interventions: Breath-Body-Mind (BBM), Survivorship education program (SEP); Behavioral
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 2
States / cities: Birmingham, Alabama

Conditions: Insomnia Chronic, Multiple Sclerosis
Interventions: Mindfulness Intervention, Sleep Hygiene; Behavioral
Lead sponsor: Griffin Hospital; Other
Eligibility: 18 Years and older
Enrollment: 49 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Derby, Connecticut

Conditions: Allergic Asthma
Interventions: Whole lung antigen challenge, segmental allergen challenge; Biological
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 50 Years
Enrollment: 43 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Stress, Mental Health Wellness 1
Interventions: HeartBot App; Behavioral
Lead sponsor: Ranjani Iyer; Other
Eligibility: 14 Years and older
Enrollment: 88 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Novi, Michigan

Conditions: Caregiver Burden, Stress, Depression, Anxiety, Cardiovascular Diseases
Interventions: Confident Caregiver Intervention; Behavioral
Lead sponsor: University of California, Davis; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Microbiome, Stress, Food Allergy in Infants
Interventions: Cow's Milk, Soy Milk; Other
Lead sponsor: University of Idaho; Other
Eligibility: 18 Years and older · Female only
Enrollment: 38 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Moscow, Idaho

Conditions: Sleep
Interventions: Construction Virtual Reality Stress Challenges, No Construction Virtual Reality Stress Challenges; Other
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 21 Years to 49 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Opioid Use Disorder, Behavioral Symptoms, Psychiatric or Mood Diseases or Conditions
Interventions: Remote Motivational Enhancement (RME) Intervention Arm, Information Only; Behavioral · Other
Lead sponsor: Cambridge Health Alliance; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Cambridge, Massachusetts

Conditions: Breast Cancer, Lung Cancer, Colon Cancer, Solid Tumor, Adult
Interventions: PEPRR, Pep-Pal; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 64 Years
Enrollment: 538 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Traumatic Brain Injury, Chronic Pain, Post Traumatic Stress Disorder, Depression, Anxiety
Interventions: ACT on Life, Education, Resources, and Support; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 176 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Stress, Stress, Psychological, Stress Physiology, Sleep, Slow Breathing
Interventions: Slow-Paced Breathing (SPB), Mindfulness (M), Yogic Breathing (SPB+M); Behavioral
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years to 24 Years
Enrollment: 19 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: PTSD
Interventions: Cognitive Processing Therapy, STAIR Narrative Therapy; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 2
States / cities: Palo Alto, California • San Francisco, California

Conditions: Parent-Child Relations
Interventions: Family Foundations Coparenting Program; Behavioral
Lead sponsor: Penn State University; Other
Eligibility: 18 Years and older
Enrollment: 497 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2002 – 2007
U.S. locations: 1
States / cities: University Park, Pennsylvania

Conditions: Stress, Positive Affect
Interventions: Resilience Challenge; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 11,659 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Chicago, Illinois

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Peau o le Vasa: Analysis of the Efficacy and Feasibility of the PILI Lifestyle Program (PLP) + Social Determinants of Health (SDOH) Intervention and Adaptation of SDOH Measures Pilot Study

Enhancing PTSD Treatment Outcomes by Improving Patient-Provider Communication

Exposure Therapy for Auditory Sensitivity in Autism

The Effects of Over-the-Counter Products on the Skin

Virtual Reality Intervention for Patients Undergoing BMT

An Integrative, Digital Health Approach to Veteran-Centered PTSD Care

Happy Family, Healthy Kids Program

Mindfulness Based Stress Reduction for Hot Flashes

A Pragmatic Trial of Brief CBT for Anxiety in VA Primary Care

Supporting Health in Veterans With Heart Failure

Mind-Body Group Interventions for Psychological Distress in Young Breast Cancer Survivors

Mindfulness Meditation in Treating Insomnia in Multiple Sclerosis

AsthMatic Inflammation and Neurocircuitry Activation (MINA)

The Effects of the App HeartBot on the Stress and Emotional Well-Being Over a 21-day Challenge

Supporting Mental Health and Reducing Care Stress in Caregivers of Persons With Cardiovascular Disease

Investigating the Detection of Bovine and Soy Proteins in Human Milk

Assessing Construction Execution Under Sleep Impairment

Effects of RME on Engagement in Buprenorphine Treatment

Developing a Virtual Stress Management Intervention for Spousal/Partnered Caregivers of Solid Tumor Cancer Patients.

One-day Life Skills Workshop for Veterans With TBI, Pain, and Psychopathology: Evaluating Efficacy and Mechanism of Change

Interactive Effects of Mindfulness and Slow-paced Breathing

A Comparative Effectiveness Study of PTSD Treatments Among Sexual and Gender Minority Populations

Family Foundations Coparenting Pilot Trial

The Resilience Challenge: Fostering Emotional Resilience During a Time of National Stress