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ClinicalTrials.gov public records Last synced Nov 12, 2026, 12:53 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 121–144 of 145 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Stress Challenge Clear all

Conditions: Anxiety, Depressive Symptoms, Stress, Psychological
Interventions: StriveWeekly; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 1,631 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Mild Traumatic Brain Injury, Distress-based Psychopathology, Chronic Pain
Interventions: Acceptance and Commitment Therapy; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 75 Years
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Post-Traumatic Stress Disorder, Overweight and Obesity, Metabolic Syndrome, Inflammation
Interventions: Mediterranean Diet & Physical Activity, Usual Care; Behavioral
Lead sponsor: Stony Brook University; Other
Eligibility: 40 Years to 65 Years
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Commack, New York

Conditions: Depression, Alcoholism, Drug Abuse
Interventions: Interpersonal and Social Rhythm Therapy (ISRT), Bipolar-Specific Cognitive Behavioral Therapy (CBT), Mindfulness-Based Stress Reduction (MBSR), Psycho-education & Understanding Bipolar Medications Therapy; Behavioral
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 64 Years
Enrollment: 130 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2026
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Postural Orthostatic Tachycardia Syndrome, Postural Tachycardia Syndrome, Tachycardia, Arrhythmias, Cardiac, Autonomic Nervous System Diseases, Orthostatic Intolerance, Cardiovascular Diseases, Primary Dysautonomias
Interventions: phenylephrine, isoproterenol, 25 micro-Ci of radiation, Posture study with blood samples, 24-hour heart rhythm and blood pressure monitoring, Quantitative Axonal Sudomotor Reflex Testing, Autonomic function tests, Rebreathing test, Assessment of splanchnic capacitance, microneurography; Drug · Radiation · Procedure + 1 more
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years to 50 Years
Enrollment: 58 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2027
U.S. locations: 2
States / cities: Oklahoma City, Oklahoma • Nashville, Tennessee

Conditions: Binge-Eating Disorder
Interventions: Acceptance and Commitment Therapy (ACT), Brief MOVE-II control group intervention; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: San Diego, California

Conditions: Dementia, Mild Cognitive Impairment (MCI), Alzheimer Disease
Interventions: Psychoeducational skills training intervention; Behavioral
Lead sponsor: Arizona State University; Other
Eligibility: 60 Years and older
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Hypertension, Stress, Psychological
Interventions: Caregiver Training; Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 40 Years and older · Female only
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Dementia
Interventions: Tailored Activity Program, Home Safety and Education Program; Behavioral · Other
Lead sponsor: Johns Hopkins University; Other
Eligibility: 21 Years and older
Enrollment: 250 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Alteration of Cognitive Function
Interventions: Exercise Challenge; Other
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 40 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Inflammation, Depression Disorder, Mindfulness, Emotional Well-being, Physical Health, Mental Health
Interventions: Mindfulness-based cognitive therapy for perinatal depression, Pregnancy Health Group; Behavioral
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Pediatric Brain Tumor
Interventions: Survivor's Journey+; Behavioral
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 15 Years to 25 Years
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 2
States / cities: Cincinnati, Ohio • Columbus, Ohio

Conditions: Generalized Anxiety Disorder, Emotional Disorder
Interventions: 14 days of EMI, Uncertainty reappraisal training; Behavioral
Lead sponsor: Ohio University; Other
Eligibility: 18 Years and older
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Athens, Ohio

Conditions: Chronic Low-back Pain
Interventions: Spinal Manipulation Therapy (SMT), Naloxone, Placebo, Mindfulness Based Stress Reduction Therapy (MT); Other · Drug · Behavioral
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years to 75 Years
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 2
States / cities: Chicago, Illinois • Nashville, Tennessee

Conditions: Fatigue, Stress, Burnout, Professional, Musculoskeletal Pain, Back Pain, Neck Pain, Headache, Dizziness, Sleep Disturbance, Chest Pain, Syncope, Cardiovascular Diseases, Shortness of Breath, Gastrointestinal Diseases
Interventions: Not listed
Lead sponsor: TMRW Life Sciences; Industry
Eligibility: 22 Years to 65 Years
Enrollment: 123 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Coronary Endothelial Dysfunction, Apical Ballooning Syndrome, Myocardial Infarction
Interventions: Not listed
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 190 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2011
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Nicotine Dependence, Alcohol Use
Interventions: Mindfulness Training for Smokers, Interactive Learning for Smokers; Behavioral
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 29 Years
Enrollment: 55 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Autism Spectrum Disorder
Interventions: Surviving and Thriving in the Real World, Program for the Education and Enrichment of Relational Skills; Behavioral
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 15 Years to 22 Years
Enrollment: 73 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Cervical Pain
Interventions: Yoga Group Exercise, Pilates Group Mat Exercise; Other
Lead sponsor: Wayne State University; Other
Eligibility: 18 Years and older
Enrollment: 88 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 4
States / cities: Bloomfield Hills, Michigan • Detroit, Michigan • Novi, Michigan + 1 more

Conditions: Opioid Use Disorder, Opioid Withdrawal, Substance Use Disorders
Interventions: Ibogaine Hydrochloride, Extended-release naltrexone injection, 380 mg, Matching Oral Placebo, Matching Intramuscular Placebo, My-E-Health SENTINEL Digital Monitoring and Human-Gated Escalation Platform, Standardized Psychological Preparation, Integration and Recovery Support, Garmin-Enabled Longitudinal Wellness Monitoring; Drug · Device · Behavioral + 1 more
Lead sponsor: Clive Michelsen; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2029
U.S. locations: 1
States / cities: Basalt, Colorado

Conditions: Stress Disorders, Post-Traumatic, Depressive Symptoms, Anxiety Symptoms, Quality of Life
Interventions: Cognitive Processing Therapy, Present-Centered Therapy; Behavioral
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years and older
Enrollment: 129 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: PTSD, Alcohol Use Disorder, Depression, Anxiety
Interventions: Brief Unified Protocol, Psychoeducation; Behavioral
Lead sponsor: Baylor Research Institute; Other
Eligibility: 21 Years and older
Enrollment: 480 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Waco, Texas

Conditions: Posttraumatic Stress Disorder (PTSD)
Interventions: Typhoid VI Polysaccharide Vaccine Injectable Solution, Saline Placebo (0.5mL injection); Biological · Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 65 Years
Enrollment: 288 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Dietary Modification
Interventions: Tart cherry Juice, High-fat meal, Exercise; Dietary Supplement · Other
Lead sponsor: University of Georgia; Other
Eligibility: 18 Years to 30 Years · Male only
Enrollment: 13 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Athens, Georgia

Search by objective public record fields.

StriveWeekly: Self-Guided Online Intervention for Anxiety, Depression, and Stress in University Students

One-Day Life Skills Workshop for Veterans With TBI, Pain and Psychopathology

Lifestyle Intervention to Reduce Body Weight and Systemic Inflammation Among World Trade Center Responders

Suicidal Behavior in Patients Diagnosed With Bipolar Disorder

Autoimmune Basis for Postural Tachycardia Syndrome

Acceptance-based Group Intervention for Binge Eating

Early-Stage Partner in Care Living Alone Plus

Stress and Hypertension in Dementia Caregivers

Reducing Agitation in People With Dementia: the Customized Activity Trial

Exercise and Cognition Trials

Inflammatory Pathways Modulated by Prenatal Mindfulness: A Route to Improve Maternal Child Emotional Well Being and Whole Person Health

Survivors Journey+

Acceptability/Feasibility of IU Intervention

Efficacy of Spinal Manipulation Therapy or Mindfulness-based Reduction Therapy on Patients With Chronic Low Back Pain

The U.K. Embryologist Fatigue Study

The Relationship Between the Response to Mental Stress and Vascular Endothelial Function

Pilot Study on Mindfulness for Tobacco and Alcohol in University Students

Daily Living Skills Intervention for Adolescents With Autism Spectrum Disorder

Effect of Group Pilates and Yoga Exercise Classes for Chronic Cervical Pain

Medically Supervised Ibogaine With 12-Month Digital Recovery Support for Opioid Use Disorder

Treatment for Veterans With Military Sexual Trauma

Peer Delivered, Emotion Regulation-Focused Mental Health Prevention Training for Fire Fighter Trainees

Inflammatory Challenge and Fear

Antioxidant Responses to Exercise and Cherry Consumption