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Showing 1–24 of 57 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Structured Weight Loss Program Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Optimal Digital Weight Loss Treatment for Rural Individuals

NCT06105957
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Core, Facilitated Weekly Group Sessions, Counselor Crafted Feedback, Individual Coaching Calls, Pre-Scripted Feedback
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
616 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Sep 6, 2026, 2:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Inhibitory Control and Pediatric Weight Management

NCT04747548
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Kurbo Only, Kurbo + PolyRules!
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
7 Years to 13 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 18, 2022 · Synced Sep 6, 2026, 2:13 AM EDT
Completed Not applicable Interventional

Impact of a POPOP on Preoperative Health, Eligibility, and Clinical & Patient-Reported Outcomes in TJA

NCT04910048
View directory record Official record
Conditions
Osteoarthritis, Knee, Osteoarthritis, Hip, Avascular Necrosis, Rheumatoid Arthritis
Interventions
POPOP (preoperative patient optimization program), SOC (standard of care)
Other
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 80 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 6, 2026, 2:13 AM EDT
Completed Phase 2 Interventional

Lifestyle Modification and Blood Pressure Study

NCT00964847
View directory record Official record
Conditions
High Blood Pressure
Interventions
Yoga exercise program, Blood pressure education/walking program
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 75 Years
Enrollment
147 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 14, 2017 · Synced Sep 6, 2026, 2:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Get Social: Randomized Trial of a Social Network Delivered Lifestyle Intervention

NCT02646618
View directory record Official record
Conditions
Weight Loss
Interventions
Get Social, Traditional, Smartphone
Behavioral · Device
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 65 Years
Enrollment
329 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 23, 2023 · Synced Sep 6, 2026, 2:13 AM EDT
Terminated No phase listed Observational

RESCUE: Discontinuation of GLP-1

NCT07190794
View directory record Official record
Conditions
Obesity
Interventions
OverStitch™ or OverStitch NXT™, Lifestyle Modification
Device · Behavioral
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Sep 6, 2026, 2:13 AM EDT
Terminated Not applicable Interventional Results available

Diet and Exercise Program to Promote Weight Loss and Improve Health in Men With Low- or Low-Intermediate-Risk Prostate Cancer

NCT02454517
View directory record Official record
Conditions
Prostate Adenocarcinoma, Stage I Prostate Cancer AJCC V7, Stage IIA Prostate Cancer AJCC v7
Interventions
Behavioral Dietary Intervention, Exercise Intervention, Informational Intervention, Laboratory Biomarker Analysis, Quality-of-Life Assessment, Questionnaire Administration
Behavioral · Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
40 Years and older · Male only
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 3, 2023 · Synced Sep 6, 2026, 2:13 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Evaluation of a Commercial Program on Weight Loss and Health Outcomes

NCT03928483
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Modified WW Food program
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 75 Years
Enrollment
143 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 10, 2019 · Synced Sep 6, 2026, 2:13 AM EDT
Recruiting Not applicable Interventional

Optimizing Telehealth-delivery of a Weight Loss Intervention in Older Adults

NCT06044571
View directory record Official record
Conditions
Obesity, Multiple Chronic Conditions
Interventions
Prescriptive, Behavioral
Other · Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
65 Years to 85 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Sep 6, 2026, 2:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of a Structured Parent Intervention on Adolescent Weight Loss Modification Program.

NCT02086851
View directory record Official record
Conditions
Pediatric Obesity, Impact of Parent Intervention on Adolescent Weight Loss
Interventions
Lifestyle Intervention, Parent Motivational Interviewing
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
11 Years to 16 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Henrico, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 10, 2016 · Synced Sep 6, 2026, 2:13 AM EDT
Recruiting Not applicable Interventional

Effects of Exercise on Lipids and Endothelial Function in Youth

NCT07409064
View directory record Official record
Conditions
Obesity & Overweight
Interventions
Exercise Program
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
10 Years to 20 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Sep 6, 2026, 2:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Program to Reduce Incontinence by Diet and Exercise

NCT00091988
View directory record Official record
Conditions
Urinary Incontinence
Interventions
Lifestyle & Behavioral Change Program, Structured Education Program
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
30 Years and older · Female only
Enrollment
338 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
4
States / cities
Birmingham, Alabama • Little Rock, Arkansas • San Francisco, California + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 15, 2020 · Synced Sep 6, 2026, 2:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

NC Works4Health: Reducing Chronic Disease Risks in Socioeconomically Disadvantaged, Unemployed Populations

NCT04815278
View directory record Official record
Conditions
Diabetes, Chronic Disease, Psychological Distress
Interventions
Immediate Chronic Disease Prevention Program (CDPP), Workplace Equity, Job and Health Supports Employer Intervention, Delayed, attenuated Chronic Disease Prevention Program (CDPP)
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 64 Years
Enrollment
455 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Sep 6, 2026, 2:13 AM EDT
Active, not recruiting Not applicable Interventional

Solutions for Hunger And Regulating Eating

NCT05004883
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Regulation of Cues Enhanced, Behavioral Weight Loss, Nutrition Education, Stress Management and Social Support
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Sep 6, 2026, 2:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Multiple Health Behavior Change Intervention for Overweight and Obese Smokers

NCT05136430
View directory record Official record
Conditions
Smoking Cessation, Obesity
Interventions
Self-Regulation strategies + large changes (SR), Healthy Lifestyle Education (LE), Smoking Cessation Treatment
Behavioral · Other
Lead sponsor
Brown University
Other
Eligibility
18 Years to 75 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 8, 2025 · Synced Sep 6, 2026, 2:13 AM EDT
Not yet recruiting No phase listed Observational

GLP-1 Medication & Behavioral Health Programs on Weight & Metabolic Outcomes: FLOURISH and THRIVE Prospective Cohort Study

NCT07588984
View directory record Official record
Conditions
Obesity & Overweight, Weight Loss, Preventative Health, Body Weight, Cardiovascular Disease Risk Factor
Interventions
Noom Weight, Free Tier, Education-only control, Semaglutide, Tirzepatide, Microdose semaglutide, Microdose tirzepatide
Behavioral · Drug
Lead sponsor
Noom Inc.
Industry
Eligibility
18 Years to 64 Years
Enrollment
2,310 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Princeton, New Jersey
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Sep 6, 2026, 2:13 AM EDT
Completed Not applicable Interventional

FRESH-TEEN: Families Responsibility Education Support Health for Teens

NCT03674944
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Behavioral Weight Loss (BWL) + Emotion Regulation (ER), Behavioral Weight Loss (BWL)
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
13 Years to 16 Years
Enrollment
332 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
2
States / cities
La Jolla, California • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 23, 2024 · Synced Sep 6, 2026, 2:13 AM EDT
Recruiting Not applicable Interventional

EMPOWER: Effects of Weight Loss and Exercise Post-stroke

NCT05901675
View directory record Official record
Conditions
Obesity, Stroke
Interventions
Lifestyle Management Program, Post-stroke Optimization of Walking using Explosive Resistance
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
35 Years to 85 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Sep 6, 2026, 2:13 AM EDT
Completed Not applicable Interventional Results available

Novel Executive Function Training for Obesity

NCT03724396
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Behavioral Weight Loss - BWL, Novel Executive Function Training - NEXT
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Feb 14, 2024 · Synced Sep 6, 2026, 2:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Time-Restricted Feeding on Fat Loss and Cardiometabolic Risk Factors in Overweight Adults

NCT03459703
View directory record Official record
Conditions
Obesity
Interventions
Early Time-Restricted Feeding, Control Schedule, Structured Weight Loss Program
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
25 Years to 75 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 7, 2020 · Synced Sep 6, 2026, 2:13 AM EDT
Active, not recruiting Not applicable Interventional

Feasibility of the Paso Program for Patients With Metabolic Dysfunction Associated Steatotic Liver Disease

NCT06854185
View directory record Official record
Conditions
Metabolic Dysfunction Associated Steatotic Liver Disease, Overweight (BMI > 25), Metabolic Syndrome
Interventions
Paso Program
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Sep 6, 2026, 2:13 AM EDT
Recruiting Phase 4 Interventional

Optimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver Disease

NCT07058155
View directory record Official record
Conditions
Liver Cirrhoses, Portal Hypertension Related to Cirrhosis, Severe Obesity, TIPS
Interventions
Transjugular Intrahepatic Portosystemic Shunt (TIPS), Sleeve Gastrectomy, Anti-Obesity Pharmacotherapy (Class Effect), Lifestyle Counseling - Diet & Physical-Activity Program
Procedure · Drug · Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 70 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2034
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Sep 6, 2026, 2:13 AM EDT
Withdrawn Phase 2 Interventional Accepts healthy volunteers

Mechanistic Insights to Weight Loss Maintenance Through SGLT2 Inhibitors

NCT05885074
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Empagliflozin Arm, Control Arm, Exercise capacity VO2 maximum determination, Exercise Challenge
Drug · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 6, 2024 · Synced Sep 6, 2026, 2:13 AM EDT
Not yet recruiting Not applicable Interventional

Addressing Food Access and Physical Activity to Improve Diabetes Prevention Outcomes Among Underserved African Americans

NCT07560969
View directory record Official record
Conditions
Diabetes, Physical Activity, Food Security, Nutrition Security
Interventions
Culturally-tailored, enhanced adaption of Diabetes Prevention Program
Behavioral
Lead sponsor
University of Missouri, Kansas City
Other
Eligibility
18 Years and older
Enrollment
408 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2031
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 6, 2026, 2:13 AM EDT