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Showing 1–24 of 388 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Study Oral Nutritional Supplement Clear all
Recruiting Not applicable Interventional

Melatonin Effects on Cardiovascular Disease Mechanisms in Midlife Women: A Randomized Clinical Trial

NCT06826755
View directory record Official record
Conditions
Perimenopause, Hypertension
Interventions
Terry Naturally® melatonin 5mg SR, Placebo
Dietary Supplement
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years to 55 Years · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Sep 16, 2026, 6:22 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Efficacy Of Tocotrienol a Natural Vitamin E In Biopsy Wound

NCT01579227
View directory record Official record
Conditions
Scar
Interventions
Topical Tocotrienol (TCT), Oral Tocotrienol Capsules (TCT), Tamoxifen Cream, Placebo cream, placebo capsule
Device · Dietary Supplement
Lead sponsor
Chandan K Sen
Other
Eligibility
18 Years to 50 Years
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 28, 2018 · Synced Sep 16, 2026, 6:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy and Safety of 12-weeks Supplementation of Eubacterium Hallii on Insulin Sensitivity and Glycaemic Control

NCT04529473
View directory record Official record
Conditions
Pre Diabetes, Impaired Glucose Tolerance, Insulin Sensitivity, Insulin Resistance, Glucose Metabolism Disorders, Metabolic Syndrome
Interventions
Eubacterium hallii, Placebo
Dietary Supplement · Other
Lead sponsor
Atlantia Food Clinical Trials
Industry
Eligibility
21 Years to 69 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 14, 2022 · Synced Sep 16, 2026, 6:22 AM EDT
Completed Phase 2 Interventional Results available

Study of Pralatrexate to Treat Participants With Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma

NCT00998946
View directory record Official record
Conditions
Lymphoma, B-Cell
Interventions
Pralatrexate, Vitamin B12, Folic Acid
Drug · Dietary Supplement
Lead sponsor
Spectrum Pharmaceuticals, Inc
Industry
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
11
States / cities
Beverly Hills, California • Post Falls, Idaho • Chicago, Illinois + 8 more
Source: ClinicalTrials.gov public record
Updated Nov 4, 2021 · Synced Sep 16, 2026, 6:22 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Beetroot Juice and Sleep

NCT05864521
View directory record Official record
Conditions
Healthy
Interventions
Active Beetroot Juice Supplement (aBRJ), Placebo Beetroot Juice Supplement (pBRJ)
Dietary Supplement
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 7, 2026 · Synced Sep 16, 2026, 6:22 AM EDT
Terminated Early Phase 1 Interventional Results available

Vitamin D Supplementation in Women With DCIS and/or LCIS

NCT02936999
View directory record Official record
Conditions
Breast Cancer
Interventions
Cholecalciferol
Drug
Lead sponsor
Inova Health Care Services
Other
Eligibility
18 Years and older · Female only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 15, 2020 · Synced Sep 16, 2026, 6:22 AM EDT
Recruiting Not applicable Interventional

Safety, Tolerability, and Efficacy of Enteral Nutrition Versus Standard of Care Nutrition in Hematopoietic Stem Cell Transplant Patients: A Pilot Study

NCT06004063
View directory record Official record
Conditions
Stem Cell
Interventions
Enteral nutrition (EN), Standard care parenteral nutrition (PN)
Dietary Supplement · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Sep 16, 2026, 6:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Acute Effects of Onnit Alpha Brain on Cognition and Mood States

NCT07495592
View directory record Official record
Conditions
Cognitive, Mood and Cognitive Performance, Sleep Deprivation, Executive Function (Cognition), Fatigue
Interventions
Alpha Brain proprietary cognitive dietary supplement, Alpha Brain 2.0 proprietary cognitive dietary supplement, Controlled Placebo
Dietary Supplement
Lead sponsor
Applied Science & Performance Institute
Industry
Eligibility
20 Years to 59 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Sep 16, 2026, 6:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Magnesium Supplementation on Body Composition

NCT06703099
View directory record Official record
Conditions
Body Composition Changes
Interventions
Magnesium Supplementation
Dietary Supplement
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 30 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Davie, Florida
Source: ClinicalTrials.gov public record
Updated Jun 5, 2025 · Synced Sep 16, 2026, 6:22 AM EDT
Completed Not applicable Interventional

Pilot Study of Vitamin K2 (MK-7) and Vitamin D3 Supplementation and the Effects on PASC Symptomatology and Inflammatory Biomarkers

NCT05356936
View directory record Official record
Conditions
Post-acute COVID-19 Syndrome
Interventions
Vitamin K2 (MK-7), Vitamin D3
Dietary Supplement
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 26, 2024 · Synced Sep 16, 2026, 6:22 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Study of Pralatrexate & Gemcitabine With B12 & Folic Acid to Treat Relapsed/Refractory Lymphoproliferative Malignancies

NCT00481871
View directory record Official record
Conditions
Relapsed or Refractory Lymphoproliferative Malignancies, Hodgkin's Lymphoma, Peripheral T-cell Lymphoma, B-cell Lymphoma, Waldenstrom's Macroglobulinemia
Interventions
Pralatrexate Injection, Gemcitabine Hydrochloride, Vitamin B12, Folic Acid
Drug · Dietary Supplement
Lead sponsor
Acrotech Biopharma Inc.
Industry
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
15
States / cities
Los Angeles, California • Stanford, California • Denver, Colorado + 11 more
Source: ClinicalTrials.gov public record
Updated Jan 6, 2020 · Synced Sep 16, 2026, 6:22 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Impact of Mulberry Leaf on Type 2 Diabetes

NCT00795704
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Mulberry Leaf Extract, Placebo
Drug
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Aug 8, 2012 · Synced Sep 16, 2026, 6:22 AM EDT
Completed Phase 1 Interventional

Lipoic Acid as a Treatment for Acute Optic Neuritis

NCT01294176
View directory record Official record
Conditions
Optic Neuritis
Interventions
Lipoic Acid
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 65 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 25, 2019 · Synced Sep 16, 2026, 6:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Dietary Supplement With and Without a Probiotic

NCT04433208
View directory record Official record
Conditions
Healthy Adult Subjects
Interventions
Complex oligosaccharide, Probiotic, PPI, H2 Blocker
Dietary Supplement · Other
Lead sponsor
Prolacta Bioscience
Industry
Eligibility
18 Years to 44 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Cypress, California
Source: ClinicalTrials.gov public record
Updated Mar 17, 2025 · Synced Sep 16, 2026, 6:22 AM EDT
Completed Early Phase 1 Interventional

Resistance Training +/- Creatine for Metastatic Prostate Cancer Patients

NCT03987217
View directory record Official record
Conditions
Fatigue, Metastatic Prostate Carcinoma, Sedentary Lifestyle, Stage IV Prostate Cancer AJCC (American Joint Committee on Cancer) v8, Stage IVA Prostate Cancer AJCC (American Joint Committee on Cancer) v8, Stage IVB Prostate Cancer AJCC (American Joint Committee on Cancer) v8
Interventions
Creatine Monohydrate, Exercise Intervention, Questionnaire Administration
Dietary Supplement · Behavioral · Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older · Male only
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 13, 2025 · Synced Sep 16, 2026, 6:22 AM EDT
Completed Phase 1 Interventional Results available

A Phase 1 Study of LY2787106 in Cancer and Anemia

NCT01340976
View directory record Official record
Conditions
Anemia
Interventions
LY2787106, Iron Supplementation
Drug · Dietary Supplement
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
9
States / cities
La Jolla, California • Santa Monica, California • Indianapolis, Indiana + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 2, 2018 · Synced Sep 16, 2026, 6:22 AM EDT
Not yet recruiting Not applicable Interventional

Pycnogenol (French Maritime Pine Bark) for the Treatment of Gulf War Illness

NCT07266571
View directory record Official record
Conditions
Gulf War Syndrome
Interventions
Placebo, Pycnogenol, 100mg, Pycnogenol, 200mg, Pycnogenol, 400mg, Pycnogenol, 600mg
Other · Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older · Male only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Sep 16, 2026, 6:22 AM EDT
Not yet recruiting Phase 2 Interventional

Herbal Supplement (Biocidin REMOVE) for Bacterial Overgrowth in Irritable Bowel Syndrome

NCT07768267
View directory record Official record
Conditions
Irritable Bowel Syndrome (IBS), Small Intestinal Bacterial Overgrowth Syndrome (SIBO)
Interventions
Biocidin REMOVE, Placebo
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Sep 16, 2026, 6:22 AM EDT
Completed Phase 2 Interventional Results available

Study of Pralatrexate to Treat Advanced or Metastatic Relapsed Transitional Cell Carcinoma of the Urinary Bladder

NCT00722553
View directory record Official record
Conditions
Carcinoma, Transitional Cell, Bladder Cancer, Bladder Neoplasm
Interventions
Pralatrexate Injection, Vitamin B12, Folic Acid
Drug · Dietary Supplement
Lead sponsor
Acrotech Biopharma Inc.
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
4
States / cities
Tucson, Arizona • Atlanta, Georgia • Rochester, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Sep 16, 2026, 6:22 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Efficacy of Daily Vitamin D3 Supplementation in Normal Weight Adolescents

NCT01058720
View directory record Official record
Conditions
Vitamin D Deficiency
Interventions
Vitamin D3
Dietary Supplement
Lead sponsor
Mayo Clinic
Other
Eligibility
12 Years to 18 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 31, 2015 · Synced Sep 16, 2026, 6:22 AM EDT
Active, not recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

Effect of a Daily Supplement on Plasma PAI-1 Levels

NCT07469475
View directory record Official record
Conditions
Aging, Endothelial Dysfunction, Senescence
Interventions
Supplement with ginger extract, L-citrulline, Paullinia cupana, and muira puama
Dietary Supplement
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
2
States / cities
Los Angeles, California • Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Sep 16, 2026, 6:22 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Efficacy Study of AlphaBRAIN Administered Orally

NCT02739139
View directory record Official record
Conditions
Cognitive Functioning
Interventions
AlphaBrain
Dietary Supplement
Lead sponsor
Onnits Labs, LLC
Industry
Eligibility
18 Years to 35 Years
Enrollment
73 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 14, 2016 · Synced Sep 16, 2026, 6:22 AM EDT
Recruiting Phase 2Phase 3 Interventional

MitoQ for Early-phase Schizophrenia-spectrum Disorder and Mitochondrial Dysfunction

NCT06191965
View directory record Official record
Conditions
Schizophrenia and Related Disorders, Mitochondrial Alteration, Cognitive Impairment
Interventions
MitoQ, Placebo
Drug
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 35 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
New Haven, Connecticut • Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 24, 2025 · Synced Sep 16, 2026, 6:22 AM EDT
Terminated Not applicable Interventional

Extended-Release Melatonin in Patients With Rapid Eye Movement Sleep Behavior Disorder

NCT05307770
View directory record Official record
Conditions
Rapid Eye Movement Sleep Behavior Disorder, Parkinson Disease
Interventions
Immediate Release Melatonin, Extended Release Melatonin
Dietary Supplement
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated May 28, 2024 · Synced Sep 16, 2026, 6:22 AM EDT