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Showing 1–23 of 23 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Subcuticular staple Clear all
Completed Phase 2 Interventional Results available

Randomized Clinical Trial of Skin Closure With Staples Versus Suture

NCT01977612
View directory record Official record
Conditions
Wound Infection, Wound Complication
Interventions
4-0 monofilament suture, Stainless steel staples
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
173 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 30, 2017 · Synced Sep 3, 2026, 5:13 AM EDT
Completed Not applicable Interventional Results available

Dermabond PRINEO for Total Shoulder Arthroplasty

NCT03860181
View directory record Official record
Conditions
Surgical Wound, Shoulder Arthritis, Surgical Incision
Interventions
Subcuticular Sutures - Surgeon 1, Metal Staples - Surgeon 2, PRINEO - Surgeon 1, PRINEO - Surgeon 2
Procedure · Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 30, 2021 · Synced Sep 3, 2026, 5:13 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Sutures vs. Staples Skin Closure After C-section in Obese Patients

NCT01820221
View directory record Official record
Conditions
Obesity, Pregnancy
Interventions
Suture vs. staples closure method after c-section in obese women.
Procedure
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Feb 2, 2017 · Synced Sep 3, 2026, 5:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Comparison of INSORB Staples With Metal Staples in Total Hip Replacement

NCT00940446
View directory record Official record
Conditions
Erythema, Drainage, Bruising, Pain
Interventions
Insorb staples, metal staples (Ethicon metal stapler)
Device
Lead sponsor
Orthopaedic Research Foundation
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 29, 2018 · Synced Sep 3, 2026, 5:13 AM EDT
Completed Not applicable Interventional

Cesarean Wound Closure in Women With BMI 40 or Greater

NCT02549131
View directory record Official record
Conditions
C.Delivery; Penetration, Pregnant Uterus, by Instrument, Obesity
Interventions
Randomizing to Suture or Staple closure of Cesarean section
Procedure
Lead sponsor
Pediatrix
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
232 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
2
States / cities
Phoenix, Arizona • Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 25, 2022 · Synced Sep 3, 2026, 5:13 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Use of Insorb Absorbable Vicryl Staples in Skin Closure for Cesarean Section

NCT01446627
View directory record Official record
Conditions
Wound Infection
Interventions
There is no intervention for this study
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
14 Years to 50 Years · Female only
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 2, 2013 · Synced Sep 3, 2026, 5:13 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Comparison of Adhesive Latch Device to Subcuticular Skin Closure at the Time of Cesarean Section

NCT03052647
View directory record Official record
Conditions
Wound
Interventions
Dermaclip, Subcuticular suture
Device
Lead sponsor
Rubino Ob-Gyn Group
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 14, 2017 · Synced Sep 3, 2026, 5:13 AM EDT
Completed Not applicable Interventional

Wound Closure Techniques in Primary Spine Surgery

NCT04396613
View directory record Official record
Conditions
Spinal Injuries
Interventions
Closure technique
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Sep 3, 2026, 5:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cesarean Trial of Staples vs. Sutures

NCT01211600
View directory record Official record
Conditions
Cesarean Section, Wound Complications, Patient Satisfaction, Pain Measurement
Interventions
Staples, Suture
Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
Female only
Enrollment
746 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
2
States / cities
New Haven, Connecticut • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 25, 2019 · Synced Sep 3, 2026, 5:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Comparative Study of Incision Closure Methods for Total Knee Replacement

NCT01088074
View directory record Official record
Conditions
Total Knee Replacement Closure, Wound Closure
Interventions
Histoacryl Tissue Adhesive, Dermabond, Staples, Monocryl 4-0
Device
Lead sponsor
Foundation for Southwest Orthopedic Research
Other
Eligibility
21 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 21, 2012 · Synced Sep 3, 2026, 5:13 AM EDT
Terminated Not applicable Interventional Results available

Staples Versus Suture for Cesarean Wound Closure

NCT01008449
View directory record Official record
Conditions
Wound
Interventions
Surgical staples, Absorbable Surgical Suture
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
16 Years and older · Female only
Enrollment
398 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 2, 2014 · Synced Sep 3, 2026, 5:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Perfusion Assessment of Wound Closure Techniques in Primary Total Knee Arthroplasty

NCT01924403
View directory record Official record
Conditions
Total Knee Arthroplasty
Interventions
Staple Closure, Vertical Mattress Closure, Running Subcuticular Closure
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 15, 2015 · Synced Sep 3, 2026, 5:13 AM EDT
Not yet recruiting Not applicable Interventional

Absorbable Staples Versus Conventional Skin Closure in Women Undergoing Cesarean Delivery

NCT07167199
View directory record Official record
Conditions
Pregnancy
Interventions
Subcuticular monocryl suture, Subcuticular absorbable staple using Insorb device
Procedure · Device
Lead sponsor
Inova Health Care Services
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
237 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Falls Church, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Sep 3, 2026, 5:13 AM EDT
Completed Not applicable Interventional Results available

A Study Investigating the Efficacy of Various Wound Closure Devices in Reducing Postoperative Wound Complications

NCT03134209
View directory record Official record
Conditions
Joint Disease, Arthropathy
Interventions
Zipper surgical skin closure, Monocryl + Dermabond, Polyester mesh + Dermabond
Device · Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 13, 2021 · Synced Sep 3, 2026, 5:13 AM EDT
Terminated Phase 1 Interventional Results available

INSORB Versus Subcuticular Sutures at Cesarean Section

NCT01687972
View directory record Official record
Conditions
Cesarean Section, Pregnancy
Interventions
Insorb absorbable staples, Absorbable sutures
Combination Product
Lead sponsor
Johns Hopkins University
Other
Eligibility
16 Years to 50 Years · Female only
Enrollment
187 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 1, 2018 · Synced Sep 3, 2026, 5:13 AM EDT
Completed Not applicable Interventional

A Randomized Trial of Ostomy Closure Techniques

NCT01713452
View directory record Official record
Conditions
Wound Infection
Interventions
Purse string closure, Primary closure
Procedure
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 31, 2019 · Synced Sep 3, 2026, 5:13 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Post-Operative Cesarean Section Cosmesis

NCT06412978
View directory record Official record
Conditions
Cesarean Delivery
Interventions
absorbable subcuticular polyglycolic acid staples (INSORB), subcuticular, polyglecaprone suture (Monocryl)
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 15, 2026 · Synced Sep 3, 2026, 5:13 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Outcomes Comparing Different Methods of Skin Closure in Patients Undergoing Head and Neck Surgery.

NCT02936063
View directory record Official record
Conditions
Surgical Wound
Interventions
Surgical staples, Subcuticular sutures
Procedure
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 5, 2017 · Synced Sep 3, 2026, 5:13 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Subcuticular Absorbable Staples Versus Conventional Skin Closure in Women Undergoing Cesarean Delivery

NCT05112640
View directory record Official record
Conditions
Operative Time, Wound Heal
Interventions
INSORB: subcuticular stapling device, Subcuticular monocryl suture manufactured by Ethicon
Device
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
117 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 20, 2024 · Synced Sep 3, 2026, 5:13 AM EDT
Completed Not applicable Interventional Results available

Comparison of Staples Versus Prolene Suture for Skin Closure at Cesarean Delivery

NCT01509950
View directory record Official record
Conditions
Pregnancy, Cesarean Section
Interventions
Staples, Prolene non-absorbable sutures, Absorbable Sutures
Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Mar 3, 2019 · Synced Sep 3, 2026, 5:13 AM EDT
Completed Not applicable Interventional

A Study Assessing Circulation Around Surgical Incisions at the Time of Laparotomy Closure

NCT03408366
View directory record Official record
Conditions
Laparotomy
Interventions
Laparotomy, ICG, Spectrum NIR imaging system
Procedure · Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
8
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 1, 2022 · Synced Sep 3, 2026, 5:13 AM EDT
Completed Not applicable Interventional Results available

Comparison of Staples Versus Subcuticular Suture in Class III Obese Women Undergoing Cesarean Delivery

NCT02466776
View directory record Official record
Conditions
Obesity, Severe, Cesarean Section
Interventions
Absorbable subcuticular suture, Stainless steel staples
Device
Lead sponsor
MemorialCare Health System
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
238 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
4
States / cities
Long Beach, California • Orange, California
Source: ClinicalTrials.gov public record
Updated Jan 8, 2024 · Synced Sep 3, 2026, 5:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Clinical Trial of Subcuticular Staples Versus Subcuticular Suture for Cesarean Section Skin Closure

NCT01753518
View directory record Official record
Conditions
Surgical Wound
Interventions
Subcuticular suture, Subcuticular staple
Device
Lead sponsor
Margaret L. Dow, M.D.
Other
Eligibility
18 Years and older · Female only
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 29, 2015 · Synced Sep 3, 2026, 5:13 AM EDT