- Conditions
- Migraine, Headaches
- Interventions
- 100 mg Sumatriptan Tablet and OPTINOSE Placebo delivered nasally, OPTINOSE SUMATRIPTAN delivered nasally and placebo tablet
- Drug
- Lead sponsor
- Avanir Pharmaceuticals
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 275 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2014
- U.S. locations
- 13
- States / cities
- San Francisco, California • Santa Monica, California • Fairfied, Connecticut + 10 more
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Showing 1–24
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- Conditions
- Migraine Headaches
- Interventions
- sumatriptan, naproxen sodium
- Drug
- Lead sponsor
- POZEN
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 1,200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2005
- U.S. locations
- 2
- States / cities
- Chapel Hill, North Carolina • Nashville, Tennessee
- Conditions
- Migraine
- Interventions
- sumatriptan succinate 85 mg/naproxen sodium 500 mg (Treximet)
- Drug
- Lead sponsor
- Cady, Roger, M.D.
- Individual
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 147 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009 – 2010
- U.S. locations
- 8
- States / cities
- San Francisco, California • Kalamazoo, Michigan • Springfield, Missouri + 5 more
- Conditions
- Migraine
- Interventions
- sumatriptan and Treximet
- Drug
- Lead sponsor
- Gary E. Ruoff, M.D.
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009 – 2011
- U.S. locations
- 1
- States / cities
- Kalamazoo, Michigan
- Conditions
- Migraine Disorders
- Interventions
- NP101 Sumatriptan Iontophoretic Transdermal Patch
- Drug
- Lead sponsor
- NuPathe Inc.
- Industry
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 4 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008
- U.S. locations
- 1
- States / cities
- Saint Paul, Minnesota
- Conditions
- Migraine Disorders
- Interventions
- Combination Product (sumatriptan succinate / naproxen sodium), RELPAX(eletriptan) 40mg Tablet
- Drug
- Lead sponsor
- GlaxoSmithKline
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006
- U.S. locations
- 1
- States / cities
- Lexington, Kentucky
- Conditions
- Post-traumatic Headache
- Interventions
- Sumatriptan 100 mg
- Drug
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2018
- U.S. locations
- 2
- States / cities
- Seattle, Washington
- Conditions
- Migraine Disorders
- Interventions
- Sumatriptan and Naproxen Sodium, Placebo
- Drug
- Lead sponsor
- GlaxoSmithKline
- Industry
- Eligibility
- 12 Years to 17 Years
- Enrollment
- 589 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2010
- U.S. locations
- 79
- States / cities
- Gilbert, Arizona • Litchfield Park, Arizona • Phoenix, Arizona + 71 more
- Conditions
- Migraine
- Interventions
- Sumatriptan/Naproxen Sodium, Naproxen Sodium
- Drug
- Lead sponsor
- Cady, Roger, M.D.
- Individual
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2012
- U.S. locations
- 2
- States / cities
- Newport Beach, California • Springfield, Missouri
- Conditions
- Migraine
- Interventions
- Treximet, Placebo
- Drug
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 36 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2013
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Lactating Women on Select DOI, Breastfed Infants of Mothers on Select DOI
- Interventions
- Tranexamic acid (TXA), labetalol, metformin, nifedipine, clindamycin, oxycodone, azithromycin, escitalopram, sertraline, ondansetron, Ciprofloxacin, Doxycycline, Levofloxacin, Methylphenidate, Sumatriptan, Citalopram, Cyclobenzaprine, Furosemide, Gabapentin, Hydrochlorothiazide, Hydroxyurea, Rosuvastatin, Topiramate, Trazodone, Valganciclovir, Venlafaxine, Verapamil, Remdesivir, Anakinra, Tocilizumab, Fluvoxamine, Amoxicillin, Bupropion, Duloxetine, Hydrocodone, Levetiracetam, Paroxetine, Buprenorphine
- Drug
- Lead sponsor
- Duke University
- Other
- Eligibility
- Not listed
- Enrollment
- 1,600 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2028
- U.S. locations
- 20
- States / cities
- La Jolla, California • Loma Linda, California • Chicago, Illinois + 15 more
- Conditions
- Delayed Alcohol Induced Headache
- Interventions
- VVD-101, Placebo
- Drug
- Lead sponsor
- Cady, Roger, M.D.
- Individual
- Eligibility
- 21 Years and older
- Enrollment
- 31 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 2
- States / cities
- Mountain View, California • Springfield, Missouri
- Conditions
- Migraine Disorders
- Interventions
- sumatriptan succinate/naproxen sodium, placebo
- Drug
- Lead sponsor
- GlaxoSmithKline
- Industry
- Eligibility
- 18 Years to 65 Years · Female only
- Enrollment
- 320 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006
- U.S. locations
- 34
- States / cities
- Mesa, Arizona • Little Rock, Arkansas • Fair Oaks, California + 31 more
- Conditions
- Migraine Disorders
- Interventions
- NP101 - Sumatriptan iontophoretic transdermal patch, Placebo
- Drug
- Lead sponsor
- NuPathe Inc.
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 530 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009
- U.S. locations
- 34
- States / cities
- Phoenix, Arizona • Little Rock, Arkansas • Newport Beach, California + 31 more
- Conditions
- Migraine Headache, Cognitive Impairment
- Interventions
- Treximet, Migraine rescue medication of choice
- Drug
- Lead sponsor
- Neurological Research Center
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009
- U.S. locations
- 1
- States / cities
- Bennington, Vermont
- Conditions
- Migraine Headaches
- Interventions
- sumatriptan, naproxen sodium
- Drug
- Lead sponsor
- POZEN
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 1,400 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2005
- U.S. locations
- 2
- States / cities
- Little Rock, Arkansas • Chapel Hill, North Carolina
- Conditions
- Migraine Disorders
- Interventions
- Placebo, Combination Product (sumatriptan succinate/naproxen sodium)
- Drug
- Lead sponsor
- GlaxoSmithKline
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 169 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2007
- U.S. locations
- 28
- States / cities
- Jasper, Alabama • Oceanside, California • San Francisco, California + 25 more
- Conditions
- Migraine Disorders
- Interventions
- sumatriptan succinate/naproxen sodium, placebo
- Drug
- Lead sponsor
- GlaxoSmithKline
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 623 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2006
- U.S. locations
- 52
- States / cities
- Anniston, Alabama • Tuscaloosa, Alabama • Mesa, Arizona + 48 more
- Conditions
- Acute Migraine Headache
- Interventions
- prochlorperazine and benadryl IV, Imitrex SubQ, saline IV
- Drug
- Lead sponsor
- United States Naval Medical Center, Portsmouth
- Federal
- Eligibility
- 18 Years to 50 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007
- U.S. locations
- 1
- States / cities
- Portsmouth, Virginia
- Conditions
- Chronic Migraine
- Interventions
- Sumatriptan/Naproxen Sodium, Naproxen Sodium
- Drug
- Lead sponsor
- Cady, Roger, M.D.
- Individual
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 56 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2012
- U.S. locations
- 2
- States / cities
- Springfield, Missouri • San Antonio, Texas
- Conditions
- Acute Migraine
- Interventions
- Not listed
- Lead sponsor
- Mclean Hospital
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 2 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2012
- U.S. locations
- 1
- States / cities
- Belmont, Massachusetts
- Conditions
- Migraine
- Interventions
- Naproxen, Sumatriptan, Migraine education, Reenforcement of diagnosis, Typical care
- Drug · Behavioral · Other
- Lead sponsor
- Montefiore Medical Center
- Other
- Eligibility
- 21 Years to 70 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2012
- U.S. locations
- 1
- States / cities
- The Bronx, New York
- Conditions
- Migraine
- Interventions
- Sumatriptan
- Drug
- Lead sponsor
- Optinose US Inc.
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012
- U.S. locations
- 1
- States / cities
- Neptune City, New Jersey
- Conditions
- Migraine Disorders
- Interventions
- Sumatriptan succinate, NP101 Study Patch
- Drug
- Lead sponsor
- NuPathe Inc.
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 23 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2009
- U.S. locations
- 1
- States / cities
- Hallandale, Florida