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ClinicalTrials.gov public records Last synced Oct 21, 2026, 6:51 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 865–888 of 2,923 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Supplement Clear all
Recruiting Not applicable Interventional

Single Versus Dual Implant Fixation of Distal Femur Fractures

NCT06286670
View directory record Official record
Conditions
Articular Fractures
Interventions
Single Implant Fixation, Dual Implant Fixation
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
16
States / cities
Birmingham, Alabama • Los Angeles, California • Atlanta, Georgia + 13 more
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Vascular Inflammation and Anti-inflammatory Supplements After Adverse Pregnancy Outcomes

NCT04633551
View directory record Official record
Conditions
Pre-Eclampsia, Pre-Term, Intrauterine Growth Restriction, Hypertension in Pregnancy
Interventions
Anti-inflammatory supplement
Dietary Supplement
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 21, 2023 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Not applicable Interventional

The Effects of Micronutrients in Combination With Usual Care in Type 2 Diabetes

NCT01738802
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Anti-oxidant and micronutrient, Placebo
Dietary Supplement · Drug
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
50 Years and older
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
2
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 28, 2016 · Synced Oct 21, 2026, 6:51 AM EDT
Not yet recruiting Not applicable Interventional

Assessing Treatment With High-phenolic EVOO Supplements for Neurovascular Activity

NCT07741773
View directory record Official record
Conditions
Mild Cognitive Impairment (MCI)
Interventions
EVOO-phenolics dietary supplement, Placebo
Dietary Supplement
Lead sponsor
Augusta University
Other
Eligibility
50 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 21, 2026, 6:51 AM EDT
Recruiting Not applicable Interventional

B6 Administration for Levetiracetam-Associated Neurobehavioral Changes and Epilepsy

NCT07271966
View directory record Official record
Conditions
Brain Tumor Related Epilepsy (BTRE)
Interventions
Vitamin B6 100 MG
Dietary Supplement
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study to Evaluate Your Super's Moon Balance and Its Impact on Premenstrual Syndrome

NCT05237661
View directory record Official record
Conditions
PMS, Menstrual Discomfort, Menstrual Pain
Interventions
Moon Balance
Dietary Supplement
Lead sponsor
Your Super, INC.
Industry
Eligibility
18 Years to 40 Years · Female only
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Jun 21, 2022 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Immune Function and Muscle Adaptations to Resistance Exercise in Older Adults

NCT02261961
View directory record Official record
Conditions
Sarcopenia, Aging, Immune Function
Interventions
TDAP, Acute Resistance Exercise, Resistance Exercise Training, Post-training Follow-up, Nutritional Supplement (Muscle Armor), Placebo (Kool-Aid)
Biological · Other · Dietary Supplement
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
60 Years to 80 Years
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
North Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Sep 28, 2021 · Synced Oct 21, 2026, 6:51 AM EDT
Recruiting Early Phase 1 Interventional

Supplemental Oxygen in Pulmonary Embolism (SO-PE)

NCT05891886
View directory record Official record
Conditions
Pulmonary Embolism, Venous Thromboembolism, Metabolomics, Oxygen Inhalation Therapy
Interventions
Oxygen Therapy, Non-rebreather mask
Drug · Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 15, 2025 · Synced Oct 21, 2026, 6:51 AM EDT
Recruiting Not applicable Interventional

Anti-inflammatory Activities of Vitamin C Supplementation on the Gut Barrier Function in Adults With Obesity

NCT07151105
View directory record Official record
Conditions
Adequate Vitamin C Status, Inadequate Vitamin C Status
Interventions
Vitamin C Supplement + Low Vitamin C Diet, Placebo + Low Vitamin C Diet
Dietary Supplement
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 50 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Citicoline Effects on Cortical Membrane Structure and Function

NCT02705066
View directory record Official record
Conditions
Healthy
Interventions
Citicoline supplement, Placebo supplement
Dietary Supplement
Lead sponsor
Kyowa Hakko Bio Co., Ltd.
Industry
Eligibility
40 Years to 60 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated May 23, 2019 · Synced Oct 21, 2026, 6:51 AM EDT
Withdrawn Not applicable Interventional

End-Of-Life Decision Making and Preparedness Planning Among Heart Failure Patients Hospitalized for Advanced Disease

NCT02398617
View directory record Official record
Conditions
Heart Failure
Interventions
Decision Making Intervention
Other
Lead sponsor
Saint Luke's Health System
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 19, 2021 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Caloric Restriction and Protein Intake on Metabolism and Anabolic Sensitivity

NCT02945410
View directory record Official record
Conditions
Weight Loss, Starvation
Interventions
Caloric Restriction, Protein, Exercise, Calcium and Vitamin D, Maltodextrin
Other · Dietary Supplement
Lead sponsor
University of Nebraska Lincoln
Other
Eligibility
19 Years to 30 Years · Male only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Dec 19, 2019 · Synced Oct 21, 2026, 6:51 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Cardiac and Vascular Responses to Creatine Supplementation in Elderly Men

NCT05329480
View directory record Official record
Conditions
Cardiac Function and Hemodynamics
Interventions
Creatine Monohydrate, Maltodextrin
Dietary Supplement
Lead sponsor
Radford University
Other
Eligibility
55 Years to 80 Years · Male only
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 16, 2024 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Feasibility or Oral Lactoferrin to Prevent Iron Deficiency Anemia in Obese Pregnancy

NCT04810546
View directory record Official record
Conditions
Iron-deficiency, Pregnancy Anemia, Obesity
Interventions
Jarrow Formulas Oral Bovine Lactoferrin Supplement
Dietary Supplement
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Oct 21, 2026, 6:51 AM EDT
Terminated Phase 2 Interventional

Phase 2 Study to Examine Grape Seed Extract as an Anti-Oligomerization Agent in Alzheimer's Disease (AD)

NCT02033941
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
Meganatural-Az Grapeseed Extract, Placebo
Drug
Lead sponsor
Hillel Grossman
Other
Eligibility
Not listed
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Phase 2 Interventional Results available

Supplements, Placebo, or Rosuvastatin Study

NCT04846231
View directory record Official record
Conditions
Hypercholesterolemia
Interventions
Fish Oil, Cinnamon, Garlique,Turmeric, Plant Sterol, Red Yeast Rice, Rosuvastatin, Placebo
Dietary Supplement · Drug · Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
40 Years to 75 Years
Enrollment
203 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 25, 2023 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Phase 1Phase 2 Interventional

Ready to Use Therapeutic Food (RUTF) to Promote Growth in Cystic Fibrosis

NCT03462056
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
Cystic Fibrosis Ready to Use Supplemental Food
Dietary Supplement
Lead sponsor
Washington University School of Medicine
Other
Eligibility
2 Years to 12 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 20, 2019 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pilot Investigation of a Multinutrient Supplement on Skin Aging and Aging Metabolites in Healthy Women

NCT00541931
View directory record Official record
Conditions
Skin Diseases
Interventions
Dietary Supplement: LifePak Nano
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Nov 20, 2017 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Maternal Choline Intake on Choline Status and Health Biomarkers During Pregnancy and Lactation

NCT01127022
View directory record Official record
Conditions
Pregnancy, Lactation
Interventions
Choline Chloride
Dietary Supplement
Lead sponsor
Cornell University
Other
Eligibility
21 Years and older · Female only
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Ithaca, New York
Source: ClinicalTrials.gov public record
Updated Sep 18, 2013 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Resveratrol for the Prevention of Bone Loss in Postmenopausal Women

NCT06250283
View directory record Official record
Conditions
Low Bone Mass
Interventions
Resveratrol, Placebo
Dietary Supplement
Lead sponsor
University of Delaware
Other
Eligibility
Female only
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Phase 2 Interventional Results available

A Controlled Trial to Evaluate the Effects of GanedenBC30 on the Immune System

NCT01184456
View directory record Official record
Conditions
HIV Infection, Gastrointestinal Symptoms
Interventions
GanedenBC30, GBI-30, PTA-6086, Placebo
Dietary Supplement · Drug
Lead sponsor
AIDS Healthcare Foundation
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Beverly Hills, California
Source: ClinicalTrials.gov public record
Updated Jan 13, 2021 · Synced Oct 21, 2026, 6:51 AM EDT
Enrolling by invitation Not applicable Interventional

Evaluating an Enhanced Home-delivered Meal Program on Older Adults' Health and Well-being

NCT06401694
View directory record Official record
Conditions
Diet, Healthy, Food Insecurity, Loneliness, Quality of Life
Interventions
Home-delivered meals, Wellness check and socialization visit, Community Health Worker calls, Supplemental grocery bag
Other · Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
60 Years and older
Enrollment
1,640 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Oct 21, 2026, 6:51 AM EDT
Completed No phase listed Observational Results available

Dietary Supplement With and Without a Probiotic and/or Antibiotic

NCT05141903
View directory record Official record
Conditions
Healthy Adults
Interventions
Antibiotic, HMO Concentrate, Probiotic, Food Supplement
Dietary Supplement
Lead sponsor
Prolacta Bioscience
Industry
Eligibility
18 Years to 75 Years
Enrollment
92 participants
Timeline
2021 – 2022
U.S. locations
1
States / cities
Cypress, California
Source: ClinicalTrials.gov public record
Updated Feb 17, 2025 · Synced Oct 21, 2026, 6:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of an Aromatic Botanical Extract on Respiratory Health.

NCT04368169
View directory record Official record
Conditions
Respiratory Health
Interventions
Teramune Botanical Extract, Placebo
Dietary Supplement · Other
Lead sponsor
Nutraceuticals Research Institute
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Franklin, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 26, 2021 · Synced Oct 21, 2026, 6:51 AM EDT