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ClinicalTrials.gov public records Last synced Oct 19, 2026, 10:57 AM EDT

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Showing 25–48 of 1,843 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Supplementation Clear all
Active, not recruiting Phase 2Phase 3 Interventional Accepts healthy volunteers

Nicotinamide and Pyruvate for Open Angle Glaucoma: A Randomized Clinical Study

NCT05695027
View directory record Official record
Conditions
Primary Open Angle Glaucoma
Interventions
Dietary supplements - Nicotinamide and Pyruvate, Placebo
Drug
Lead sponsor
Columbia University
Other
Eligibility
35 Years to 85 Years
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
3
States / cities
Palo Alto, California • New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 19, 2026, 10:57 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Impacts of Nicotinamide Riboside on Functional Capacity and Muscle Physiology in Older Veterans

NCT04691986
View directory record Official record
Conditions
Sarcopenia, Nicotinamide Adenine Dinucleotide Concentration, Muscle Quality and NAD+ Content
Interventions
Nicotinamide Riboside, Placebo
Dietary Supplement · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
65 Years to 85 Years
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 19, 2026, 10:57 AM EDT
Completed Not applicable Interventional Results available

Vitamin D Supplementation in Psychiatric Illnesses

NCT01004354
View directory record Official record
Conditions
Obesity, Vitamin D Deficiency, Psychosis, Schizophrenia, Schizoaffective Disorder
Interventions
Ergocalciferols
Drug
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
10 Years to 18 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 6, 2017 · Synced Oct 19, 2026, 10:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating Whole Foods Supplementation on Cognition

NCT01672359
View directory record Official record
Conditions
Sub-optimal Cognitive Function, Sub-optimal Immune Function
Interventions
Ginkgo Synergy® and Choline, OPC Synergy® and Catalyn, Placebo
Dietary Supplement
Lead sponsor
University of Miami
Other
Eligibility
60 Years and older
Enrollment
97 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 6, 2014 · Synced Oct 19, 2026, 10:57 AM EDT
Completed Phase 1 Interventional Results available

A Phase 1 Study of LY2787106 in Cancer and Anemia

NCT01340976
View directory record Official record
Conditions
Anemia
Interventions
LY2787106, Iron Supplementation
Drug · Dietary Supplement
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
9
States / cities
La Jolla, California • Santa Monica, California • Indianapolis, Indiana + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 3, 2018 · Synced Oct 19, 2026, 10:57 AM EDT
Completed Not applicable Interventional

Supplemental Egg Protein Intervention in Older Adults

NCT03530774
View directory record Official record
Conditions
Sarcopenia, Aging
Interventions
powdered egg white protein supplement, maltodextrin supplement
Dietary Supplement
Lead sponsor
The University of Texas at San Antonio
Other
Eligibility
60 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Dec 20, 2024 · Synced Oct 19, 2026, 10:57 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Evaluation of a Daily Oral Care Lozenge on Oral Health and Quality of Life in Older Adults

NCT03693027
View directory record Official record
Conditions
Oral Health
Interventions
PTx800 lozenges, Placebo control
Dietary Supplement
Lead sponsor
Primal Therapies Inc.
Industry
Eligibility
60 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 9, 2018 · Synced Oct 19, 2026, 10:57 AM EDT
Not listed Phase 1Phase 2 Interventional

Single-dose Potassium Supplementation in Patients With ADHD for Whom the Anesthetic Lidocaine is Ineffective

NCT03563573
View directory record Official record
Conditions
ADHD
Interventions
Potassium Gluconate Oral Capsule, Placebo oral capsule
Drug
Lead sponsor
AlkaliDx, Inc.
Industry
Eligibility
13 Years to 49 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Voorhees Township, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 20, 2018 · Synced Oct 19, 2026, 10:57 AM EDT
Completed Not applicable Interventional

Effect of Supplemental Oral Curcumin in Patients With Atopic Asthma

NCT01179256
View directory record Official record
Conditions
Atopic Asthma
Interventions
CURCUMIN, no intervention other than stopping study
Dietary Supplement · Other
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 60 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Aug 11, 2010 · Synced Oct 19, 2026, 10:57 AM EDT
Completed Not applicable Interventional Results available

Effect of Vitamin D on the Honeymoon Period in Children and Adolescents With Type 1 Diabetes

NCT01724190
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
Vitamin D, Placebo
Drug
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
4 Years to 18 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 28, 2024 · Synced Oct 19, 2026, 10:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Crossover Clinical Trial Investigating the Effects of Geranylgeraniol (GG) Supplementation on Testosterone Levels in Healthy Men and Women Over an 18-week Period

NCT06747624
View directory record Official record
Conditions
Wellness, Health
Interventions
Geranylgeraniol 300 mg, Placebo
Dietary Supplement
Lead sponsor
Designs for Health
Industry
Eligibility
40 Years to 65 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Palm Coast, Florida
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 19, 2026, 10:57 AM EDT
Active, not recruiting Not applicable Interventional

Randomized Trial of Enteral Vitamin D Supplementation in Infants < 28 Weeks Gestational Age or <1000 Grams Birth Weight

NCT05694689
View directory record Official record
Conditions
Vitamin D Deficiency
Interventions
Placebo, 800 IU/day vitamin D supplementation with feedings in the first 28 days after birth, Usual Care
Dietary Supplement · Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
24 Hours to 96 Hours
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 19, 2026, 10:57 AM EDT
Active, not recruiting Not applicable Interventional

Pea Protein Oral Nutrition Supplement for the Reduction of Gastrostomy Tube Placement Rate in Patients With Locally Advanced Head and Neck Cancer Undergoing Chemoradiation Therapy

NCT05115760
View directory record Official record
Conditions
Locally Advanced Head and Neck Carcinoma
Interventions
Dietary Supplement, Quality-of-Life Assessment, Questionnaire Administration
Dietary Supplement · Other
Lead sponsor
Jonsson Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 19, 2026, 10:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Curcumin Supplementation for the Improvement of Diabetes-related Outcomes

NCT06984640
View directory record Official record
Conditions
Over Age 60, Prediabetes or Overweight
Interventions
Curcumin, Placebo
Dietary Supplement
Lead sponsor
Oklahoma State University
Other
Eligibility
60 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Stillwater, Oklahoma
Source: ClinicalTrials.gov public record
Updated May 22, 2025 · Synced Oct 19, 2026, 10:57 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Influence of Creatine Monohydrate Supplementation on Androgens and Global Hair Assessments

NCT04298840
View directory record Official record
Conditions
Dihydrotestosterone, Testosterone, Hair Loss
Interventions
Creatine Monohydrate Supplementation, Placebo Supplementation
Dietary Supplement
Lead sponsor
Texas Tech University
Other
Eligibility
18 Years to 35 Years · Male only
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Sep 14, 2021 · Synced Oct 19, 2026, 10:57 AM EDT
Completed Phase 1 Interventional

In Vitro Basophil Responsiveness to Allergen Challenge After Gamma-tocopherol Supplementation in Allergic Asthmatics

NCT00836368
View directory record Official record
Conditions
Allergic, Asthmatic, Allergy, Asthma
Interventions
gamma-tocopherol
Dietary Supplement
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 50 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 7, 2011 · Synced Oct 19, 2026, 10:57 AM EDT
Active, not recruiting Not applicable Interventional Results available

Early Protein Supplementation in Extremely Preterm Infants Fed Human Milk

NCT04325308
View directory record Official record
Conditions
Prematurity; Extreme, Feeding Disorder Neonatal, Breast Milk Expression, Growth Failure, Microbial Colonization
Interventions
Protein-enriched human milk diet, Usual human milk diet
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
1 Day to 4 Days
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 19, 2026, 10:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Soy Nuts and Cardiovascular Risk in Postmenopausal Women

NCT01740076
View directory record Official record
Conditions
Postmenopausal Women
Interventions
soy nuts
Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
21 Years and older · Female only
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 22, 2025 · Synced Oct 19, 2026, 10:57 AM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers Results available

Brain Small Chain Fatty Acid Metabolism in Parkinson Disease: Tributyrin Supplementation

NCT05446168
View directory record Official record
Conditions
Parkinson Disease
Interventions
tributyrin
Drug
Lead sponsor
Nicolaas Bohnen, MD, PhD
Other
Eligibility
45 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 23, 2025 · Synced Oct 19, 2026, 10:57 AM EDT
Completed Phase 2 Interventional

The Nutritional Supplement Phosphatidylserine in Patients With Familial Dysautonomia

NCT02276716
View directory record Official record
Conditions
Familial Dysautonomia
Interventions
Phosphatidylserine
Dietary Supplement
Lead sponsor
NYU Langone Health
Other
Eligibility
12 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 21, 2021 · Synced Oct 19, 2026, 10:57 AM EDT
Not listed Early Phase 1 Interventional Accepts healthy volunteers

Role of Gastrointestinal Microbes on Digestion of Resistant Starch and Tryptophan Availability to Humans

NCT02974699
View directory record Official record
Conditions
Type II Diabetes
Interventions
Potato Starch (Bob's Red Mill), Pregelatinized Starch (Resource ThickenUp)
Dietary Supplement
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2017
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated May 4, 2017 · Synced Oct 19, 2026, 10:57 AM EDT
Completed Not applicable Interventional

Fiber Supplementation After Bariatric Surgery

NCT05653648
View directory record Official record
Conditions
Bariatric Surgery Candidate
Interventions
Potato starch
Dietary Supplement
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Feb 29, 2024 · Synced Oct 19, 2026, 10:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Gut-microbiota Targeted Nutritional Intervention for Gut Barrier Integrity at High Altitude

NCT04111263
View directory record Official record
Conditions
Gastrointestinal Injury, Acute Mountain Sickness
Interventions
FP, Placebo, High altitude, Sea level
Dietary Supplement · Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
17 Years to 39 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 23, 2022 · Synced Oct 19, 2026, 10:57 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Changes in Amino Acid Absorption After Adding a Probiotic to an Acute Protein Feeding

NCT06701604
View directory record Official record
Conditions
Amino Acid Absorption, Probiotic
Interventions
Single Strain Probiotic + Milk Protein, Placebo + Milk Protein
Dietary Supplement
Lead sponsor
The Archer-Daniels-Midland Company
Industry
Eligibility
18 Years to 35 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Belton, Texas
Source: ClinicalTrials.gov public record
Updated Nov 22, 2024 · Synced Oct 19, 2026, 10:57 AM EDT