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Conditions: PTSD, Firearm Injury, Suicide Prevention, Firearm Safety
Interventions: Project Safe Guard - Trauma, Project Safe Guard; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years and older
Enrollment: 168 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Substance Use
Interventions: Standard Screening, Standard Psychoeducation, Standard Brief Negotiated Interview (BNI), Standard Referral to Treatment (RT), Family Screening, Family Psychoeducation, Family Brief Negotiated Interview (BNI), Family Facilitated Conversation (FC) & Referral to Treatment (RT); Behavioral
Lead sponsor: The National Center on Addiction and Substance Abuse at Columbia University; Other
Eligibility: 12 Years to 17 Years
Enrollment: 2,300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2029
U.S. locations: 1
States / cities: New York, New York

Conditions: Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Interventions: Behavioral Intervention, Survey Administration, Interview; Behavioral · Other
Lead sponsor: Fred Hutchinson Cancer Center; Other
Eligibility: 18 Years to 54 Years
Enrollment: 374 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 2
States / cities: Memphis, Tennessee • Seattle, Washington

Conditions: Depression
Interventions: RESCUE Problem Solving Intervention; Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: Not listed
Enrollment: 210 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2024
U.S. locations: 3
States / cities: Gainesville, Florida • Orlando, Florida • Tampa, Florida

Conditions: Breastfeeding, Exclusive
Interventions: MILC application, Usual care; Behavioral
Lead sponsor: Benten Technologies, Inc.; Industry
Eligibility: 18 Years to 44 Years · Female only
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 3
States / cities: Farmington, Connecticut • Research Triangle Park, North Carolina • Philadelphia, Pennsylvania

Conditions: Intervention 1: Resilience and Coping for Healthcare Group, Intervention 2: Resilience and Coping for Healthcare Plus Additional Services, Waitlist Control Group
Interventions: RCHC+, Waitlist control; Behavioral · Other
Lead sponsor: University of Illinois at Urbana-Champaign; Other
Eligibility: 18 Years and older
Enrollment: 1,100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Smoking Cessation
Interventions: Nicotine patch, Quitline Counseling Phone Calls, Counseling Sessions, Pathways to Freedom, Monetary Incentive; Drug · Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 21 Years and older
Enrollment: 1,550 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2030
U.S. locations: 5
States / cities: Phoenix, Arizona • Indianapolis, Indiana • Kansas City, Kansas + 2 more

Conditions: Type 2 Diabetes, Hypertension, Hyperlipidemia
Interventions: home health/primary care collaboration; Behavioral
Lead sponsor: Albert Einstein College of Medicine; Other
Eligibility: 30 Years and older
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Breast Carcinoma
Interventions: Best Practice, Discussion, Interview - Stakeholder, Interview - Key Informant, Interview - Ancillary studies, Patient Navigation - C Components, Patient Navigation - B components, Patient Navigation - A components, Survey Administration, Survey Administration - Ancillary studies; Other · Behavioral
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 800 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Diabetes Mellitus
Interventions: Arts-Based Storytelling Workshop Series; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 16 Years to 25 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Critical Illness, Sepsis, Shock, Septic, Shock, Respiratory Failure, Respiratory Distress Syndrome, Adult, Shock, Hypovolemic, Chronic Disease
Interventions: Peer Support with Motivational Interviewing, Usual Care Group; Behavioral
Lead sponsor: University of Texas at Austin; Other
Eligibility: 18 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Temple, Texas

Conditions: Medication Adverse Effects, Older Adults (65 Years and Older), Polypharmacy, Polypharmacy Patients, Deprescribing
Interventions: Patient-tailored deprescribing assessment and intervention; Behavioral
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 65 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Body Weight, Weight Loss, Motor Activity
Interventions: 24 months of personalized coaching through the EHR patient portal, with 24 scheduled contacts., Online self-monitoring, Real-time updates to Primary Care physicians; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 75 Years
Enrollment: 194 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Alcohol Use, Drug Use, Diagnostic Self Evaluation, Gonorrhea, Unprotected Sex, Chlamydia, Trichomonas
Interventions: Project EMPWR, Optimized Standard Care (OSC); Behavioral · Other
Lead sponsor: Johns Hopkins Bloomberg School of Public Health; Other
Eligibility: 18 Years to 49 Years
Enrollment: 350 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Fort Apache, Arizona

Conditions: Obesity, Nutrition Poor, Physical Activity, Weight Loss
Interventions: Healthy Frio In-Person Family-focused Intervention, Healthy Frio Remote Technology Family-focused Intervention, Control; Behavioral
Lead sponsor: University of Texas at Austin; Other
Eligibility: 8 Years and older
Enrollment: 260 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Pearsall, Texas

Conditions: Smoking, Cigarette, Smoking Cessation
Interventions: Varenicline, Combination nicotine patch and nicotine mini-lozenge treatment, Monetary incentives for initiating treatment, Automated tailored outreach, Care management, Wisconsin Tobacco Quit Line referral, Primary care provider referral, Untailored outreach, Multiple smoking cessation coaching calls; Drug · Behavioral · Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 210 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Tobacco Use Disorder, Nicotine Dependence
Interventions: Counseling, Contingency management, Text-based support; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 25 Years
Enrollment: 350 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Parkinson Disease, Dysarthria
Interventions: Remote speech rehabilitation; Behavioral
Lead sponsor: Florida State University; Other
Eligibility: 25 Years to 85 Years
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Tallahassee, Florida

Conditions: Irritable Bowel Syndrome, Abdominal Pain
Interventions: BodiMojo Buddy for IBS; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 13 Years to 21 Years
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Head and Neck Neoplasms, Emergency Department Presentation, Head and Neck Cancer (H&N)
Interventions: Community Health Support Specialist (CHSS) Navigation; Behavioral
Lead sponsor: University of Tennessee; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 2
States / cities: Orlando, Florida • Memphis, Tennessee

Conditions: Breast Cancer, Hormone-resistant Prostate Cancer, Recurrent Prostate Cancer
Interventions: dietary intervention, nutritional support, laboratory biomarker analysis; Dietary Supplement · Procedure · Other
Lead sponsor: University of Southern California; Other
Eligibility: 19 Years and older
Enrollment: 130 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2027
U.S. locations: 3
States / cities: Los Angeles, California • Newport Beach, California • Rochester, Minnesota

Conditions: Secondhand Smoke
Interventions: Quitline Delivered Treatment; Behavioral
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 18 Years and older
Enrollment: 484 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Teenage Pregnancy
Interventions: Girl2Girl; Behavioral
Lead sponsor: Center for Innovative Public Health Research; Other
Eligibility: 14 Years to 18 Years · Female only
Enrollment: 948 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: San Clemente, California

Conditions: Cigarette Smoking, E-Cigarette Use, Smoking Cessation
Interventions: Varenicline, Counseling, Guided Self-Change Booklets; Drug · Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: New Haven, Connecticut

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Project Safe Guard-Trauma

Primary Connections for Youth and Families

Testing Counseling and Mobile Health Interventions to Improve Physical Activity and Diet Quality in Survivors of Childhood Cancer

Spanish Intervention for Caregivers of Veterans With Stroke

MILC: A Comprehensive Mobile Application That Addresses the Breastfeeding Challenges of Low-income Hispanic Mothers

Health and Wellness in Healthcare Providers Post-disaster

My Path to Quit Tobacco

Controlling Hypertension in Diabetes- Feasibility Study

Mobile Health Patient Navigation for the Improvement of Screening and the Early Detection of Breast Cancer in Women Accessing Primary Care Clinics in Kenya

Evaluation of Arts-Based Storytelling Program in Adolescents With Diabetes

Peer Support for Post Intensive Care Syndrome Self-Management

Population Health Approach to Optimizing Medications in Older Adults

Computer-Based Weight Maintenance in Primary Care

Trial of an Adapted STD Screening and Risk Reduction Intervention

Healthy Frio: A Rural Community Partnership to Advance Latino Obesity Research

Health Systems Reach Interventions Project

Young Adult Tobacco/Nicotine and Cannabis Co-use

Dysarthria Management for Minor Groups

Mobile Self-Management of Irritable Bowel Syndrome for Adolescents

Access to Care Pilot for ED-Presenting Head and Neck Cancer Patients (ENRICH-HNC)

Controlled Low Calorie Diet in Reducing Side Effects and Increasing Response to Chemotherapy in Patients With Breast or Prostate Cancer

Parent eReferral to Tobacco Quitline

Girl2Girl: Harnessing Text Messaging to Reduce Teenage Pregnancy Among LGB Girls

Concurrent vs. Sequential Cessation of Dual Cigarette and E-cigarette Use