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Showing 1–24 of 46 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Supportive Non-directive Therapy Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Understanding and Treating Neuropsychiatric Symptoms of Pediatric Physical Illness

NCT00769353
View directory record Official record
Conditions
Inflammatory Bowel Disease, Ulcerative Colitis, Crohn's Disease, Depression
Interventions
Primary and Secondary Coping Enhancement Training, Supportive Non-directive Therapy
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years to 17 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2014
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 20, 2014 · Synced Sep 10, 2026, 10:32 AM EDT
Recruiting Not applicable Interventional

Supportive Hospital-Based Intervention for Firearm Trauma

NCT06712940
View directory record Official record
Conditions
Gun Violence Prevention, Adolescent Behavior
Interventions
Motivational Interviewing and Firearm Safety Training, with Case Management
Behavioral
Lead sponsor
Tulane University
Other
Eligibility
16 Years to 24 Years
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Feb 16, 2025 · Synced Sep 10, 2026, 10:32 AM EDT
Terminated Not applicable Interventional

Serving Women Using Opioids During Pregnancy

NCT03552120
View directory record Official record
Conditions
Opioid Use, Pregnancy Related
Interventions
MORE, Supportive Psychotherapy
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 23, 2023 · Synced Sep 10, 2026, 10:32 AM EDT
Recruiting Not applicable Interventional

Multiphase Optimization Strategy (MOST) for Treating Pediatric Post-traumatic Stress Disorder (PTSD)

NCT06956781
View directory record Official record
Conditions
PTSD, Trauma, Pediatric ALL
Interventions
Emotion Regulation, Exposure, Cognitive Processing, Bi-lateral Stimulation, Psychological Placebo
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
8 Years to 17 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Sep 10, 2026, 10:32 AM EDT
Recruiting Not applicable Interventional

A Biobehavioral Intervention for Latino/Hispanic Young Adults with Cancer

NCT06338475
View directory record Official record
Conditions
Cancer
Interventions
Goal-Focused Emotion-Regulation Therapy (GET), Individual Supportive Listening (ISL)
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 39 Years · Male only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Mar 24, 2025 · Synced Sep 10, 2026, 10:32 AM EDT
Completed Not applicable Interventional

Mobile CBT for Negative Symptoms

NCT03621774
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder
Interventions
Mobile-assisted CBT-informed Skills Training, Supportive Contact
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 60 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Nov 7, 2024 · Synced Sep 10, 2026, 10:32 AM EDT
Completed Not applicable Interventional Results available

The Use of Skills Training to Augment Compensated Work Therapy (CWT)/VI for Veterans With SMI

NCT00272168
View directory record Official record
Conditions
Mental Illness, Schizophrenia
Interventions
Maryland Program for Vocational Effectiveness, Supportive Treatment for SMI
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 16, 2016 · Synced Sep 10, 2026, 10:32 AM EDT
Recruiting Phase 1Phase 2 Interventional

RCT of Psilocybin-assisted CBT for Depression

NCT07281352
View directory record Official record
Conditions
Major Depressive Diorder
Interventions
Psilocybin (drug), cognitive behavioral therapy, Minimal supportive therapy
Drug · Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Sep 10, 2026, 10:32 AM EDT
Completed Not applicable Interventional

A Trial of Neurocognitive and Supportive Therapy Interventions for Individuals With Parkinson's Disease

NCT01646333
View directory record Official record
Conditions
Parkinson's Disease, Mild Cognitive Impairment
Interventions
Memory and Problem-Solving Intervention, Supportive Therapy
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 7, 2016 · Synced Sep 10, 2026, 10:32 AM EDT
Completed Not applicable Interventional

Reducing Depressive Symptoms in Physically Ill Youth

NCT00534911
View directory record Official record
Conditions
Inflammatory Bowel Disease, Depression
Interventions
Cognitive Behavioral Therapy, Supportive Non-directive Therapy (SNDT)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
9 Years to 17 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2019
U.S. locations
2
States / cities
Boston, Massachusetts • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 6, 2020 · Synced Sep 10, 2026, 10:32 AM EDT
Completed Not applicable Interventional

Confirming the Efficacy/Mechanism of Family Therapy for Children With Low Weight ARFID

NCT04450771
View directory record Official record
Conditions
Avoidant/Restrictive Food Intake Disorder
Interventions
Family-based Treatment for ARFID, Manualized Non-Specific Usual Care for ARFID
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
6 Years to 12 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 1, 2026 · Synced Sep 10, 2026, 10:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project HOME: Home-Based Treatment Options and Mechanisms for Eating Disorders

NCT05184556
View directory record Official record
Conditions
Anorexia Nervosa, Eating Disorders
Interventions
Family-based treatment (FBT), Integrative family therapy
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years to 18 Years
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • Pawtucket, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Sep 10, 2026, 10:32 AM EDT
Completed Not applicable Interventional

Four Models of Telephone Support for Stimulant Recovery

NCT00744068
View directory record Official record
Conditions
Drug Addiction
Interventions
Continuing Care Telephone Support
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
6
States / cities
Los Alamitos, California • Los Angeles, California • Rancho Cucamonga, California + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 27, 2016 · Synced Sep 10, 2026, 10:32 AM EDT
Completed Not applicable Interventional Results available

Stroke and CPAP Outcome Study 3

NCT06029959
View directory record Official record
Conditions
Ischemic Stroke, Intra Cerebral Hemorrhage, Obstructive Sleep Apnea, Adherence, Treatment, Motivation
Interventions
Continuous positive airway pressure (CPAP), CPAP technical support intervention, Motivational Enhancement Therapy (MET), Mobile Health intervention
Device · Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 7, 2025 · Synced Sep 10, 2026, 10:32 AM EDT
Completed Not applicable Interventional

Health Coaching for Chronic Multisymptom Illness

NCT04157101
View directory record Official record
Conditions
Pain Predominant Chronic Multisymptom Illness
Interventions
Health Coaching, Supportive Psychotherapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
East Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Sep 10, 2026, 10:32 AM EDT
Completed Phase 2Phase 3 Interventional

Prolonged Exposure Therapy for Post Traumatic Stress Disorder Following Sexual Assault

NCT00057629
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Prolonged Exposure (PE), Treatment as usual group therapy (TUGT), Supportive counseling (SC)
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 67 Years · Female only
Enrollment
187 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2009
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 12, 2015 · Synced Sep 10, 2026, 10:32 AM EDT
Completed Not applicable Interventional Results available

Financial Incentives, Randomization With Stepped Treatment Trial

NCT03089320
View directory record Official record
Conditions
Unhealthy Alcohol Use
Interventions
Contingency Management Counseling, Addiction Physician Management, Motivational Enhancement Therapy
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
7
States / cities
Los Angeles, California • Washington D.C., District of Columbia • Atlanta, Georgia + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 14, 2024 · Synced Sep 10, 2026, 10:32 AM EDT
Enrolling by invitation Not applicable Interventional

Personalizing Treatment Delivery

NCT05821634
View directory record Official record
Conditions
Anxiety Disorders and Symptoms, PTSD and Trauma-related Symptoms, Alcohol; Use, Problem; Alcohol Use Disorder
Interventions
Personalized intervention condition: Cognitive behavioral therapy skills, Therapeutic control condition: Cognitive behavioral therapy skills, Tracking control condition: Supportive counseling
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 65 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Sep 10, 2026, 10:32 AM EDT
Completed Not applicable Interventional

Increasing Treatment for Obesity Among Underserved Populations

NCT05666323
View directory record Official record
Conditions
Obesity
Interventions
Single Text Messaging (TM1), Patient Navigation (PN), Multiple Text Messaging (TM+)
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 30, 2024 · Synced Sep 10, 2026, 10:32 AM EDT
Completed Not applicable Interventional

Multisystemic Therapy to Reduce Health Disparities in Adolescents With Asthma

NCT00916240
View directory record Official record
Conditions
Asthma
Interventions
Multisystemic Therapy, Home-based, Non-Directive Family Support
Behavioral
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
12 Years to 16 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 18, 2016 · Synced Sep 10, 2026, 10:32 AM EDT
Completed Not applicable Interventional

Adapting DBT for Children With DMDD: Pilot RCT

NCT01862549
View directory record Official record
Conditions
Disruptive Mood Dysregulation Disorder
Interventions
Dialectical Behavior Therapy for children, Treatment as Usual
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
7 Years to 12 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Feb 28, 2019 · Synced Sep 10, 2026, 10:32 AM EDT
Completed Not applicable Interventional

Illness Management and Parental Adjustment to Cancer Treatment

NCT02505165
View directory record Official record
Conditions
Solid Tumor, Leukemia, Lymphoma, Brain Tumor
Interventions
IMPACT, ESO
Behavioral · Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
0 Years to 18 Years
Enrollment
279 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
3
States / cities
Cincinnati, Ohio • Dayton, Ohio • Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 12, 2022 · Synced Sep 10, 2026, 10:32 AM EDT
Recruiting Not applicable Interventional

A Biobehavioral Intervention to Reduce Adverse Outcomes in Young Adult Testicular Cancer Survivors

NCT05836688
View directory record Official record
Conditions
Testicular Cancer
Interventions
Goal-Focused Emotion-Regulation Therapy (GET), Individual Supportive Listening
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 39 Years · Male only
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Apr 30, 2025 · Synced Sep 10, 2026, 10:32 AM EDT
Active, not recruiting Not applicable Interventional

FIT Families Multicomponent Obesity Intervention for African American Adolescents

NCT04974554
View directory record Official record
Conditions
Obesity, Childhood, Metabolic Syndrome
Interventions
FIT, Home-Based Family Support
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
12 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 10, 2026, 10:32 AM EDT