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ClinicalTrials.gov public records Last synced Nov 10, 2026, 4:11 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1705–1728 of 3,155 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Supportive management Clear all

Conditions: Tobacco Use Disorder, Nicotine Dependence
Interventions: Counseling, Contingency management, Text-based support; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 25 Years
Enrollment: 350 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Alcoholism, Alcohol Use Disorder (AUD)
Interventions: Topiramate, Medical Management, Inactive Placebo; Drug · Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 70 Years
Enrollment: 320 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2020
U.S. locations: 2
States / cities: Philadelphia, Pennsylvania

Conditions: Hypertension
Interventions: Electronic Intervention; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 75 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Hypercholesterolemia
Interventions: spouse-assisted intervention; Behavioral
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: Not listed
Enrollment: 255 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Chronic Low-back Pain (cLBP), High-Impact Chronic Pain (HICP)
Interventions: ENCompaSS (Education, Navigated Care, and Supported Self-Management) with VA Stepped Usual Care; Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 530 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Breast Carcinoma, Breast Inflammatory Carcinoma, Locally Recurrent Breast Carcinoma
Interventions: Exercise Intervention, Educational Intervention, Supportive Care, Biospecimen Collection, Magnetic Resonance Imaging, Questionnaire Administration, Accelerometry, Electronic Health Record Review, Cardiopulmonary Exercise Testing; Other · Procedure
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years to 85 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 4
States / cities: Winston-Salem, North Carolina • Richmond, Virginia

Conditions: Pelvic Organ Prolapse, Prolapse
Interventions: Reia System, Standard of Care Pessary; Device
Lead sponsor: Medstar Health Research Institute; Other
Eligibility: 18 Years and older · Female only
Enrollment: 218 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 9
States / cities: Birmingham, Alabama • Palo Alto, California • Washington D.C., District of Columbia + 6 more

Conditions: Chronic Obstructive Pulmonary Disease
Interventions: Self-Management Support, COPD Education; Behavioral
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 40 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: New York, New York

Conditions: Suicide, Suicide, Attempted, Suicide and Self-harm, Suicide Threat
Interventions: Safe Alternatives for Teens and Youth - Parent (SAFETY-P), Treatment As Usual (TAU); Behavioral
Lead sponsor: Jennifer Hughes; Other
Eligibility: 10 Years to 18 Years
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 2
States / cities: Columbus, Ohio

Conditions: Pre-Exposure Prophylaxis (PrEP)
Interventions: eSTEP, Usual Care; Behavioral
Lead sponsor: San Diego State University; Other
Eligibility: 18 Years and older · Male only
Enrollment: 113 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: San Diego, California

Conditions: Recurrent T-Cell Non-Hodgkin Lymphoma, Refractory T-Cell Non-Hodgkin Lymphoma
Interventions: Bendamustine, Pralatrexate, Bone Marrow Aspiration, Bone Marrow Biopsy, Chest Radiography, Computed Tomography, Echocardiography Test, Lumbar Puncture, Magnetic Resonance Imaging, Multigated Acquisition Scan, Peripheral Blood Stem Cell Transplantation, Positron Emission Tomography, Questionnaire Administration, Total-Body Irradiation, Biospecimen Collection; Drug · Procedure · Other + 1 more
Lead sponsor: Fred Hutchinson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Cigarette Smoking, Post Traumatic Stress Disorder, Signs and Symptoms, Respiratory
Interventions: CBT-A, CBT-S; Behavioral
Lead sponsor: Stony Brook University; Other
Eligibility: 18 Years and older
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Stony Brook, New York

Conditions: HIV Infection, Sexually Transmitted Infections, Implementation
Interventions: Training Tool for Preventing HIV/AIDS among Teens (PHAT) Life; Behavioral
Lead sponsor: Oregon Research Behavioral Intervention Strategies, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Springfield, Oregon

Conditions: Substance Use Disorder, Opioid Use Disorder, Child Maltreatment, Implementation, Peer Recovery Supporters
Interventions: COSTARS, Implementation As Usual; Other
Lead sponsor: Alicia Bunger; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Methamphetamine Abuse
Interventions: Peer Contingency Management, Standard of Care Contingency Management; Behavioral
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 18 Years to 105 Years
Enrollment: 1,283 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 2
States / cities: Portland, Oregon

Conditions: Type 1 Diabetes
Interventions: Social Media; Behavioral
Lead sponsor: Seattle Children's Hospital; Other
Eligibility: 13 Years to 18 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Depression, Quality of Life, Self Efficacy, Recovery of Function, Stress, Positive Aspects of Caregiving
Interventions: Caregiver problem-solving, Standard Care; Behavioral · Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 174 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2021
U.S. locations: 3
States / cities: Gainesville, Florida • Miami, Florida • Tampa, Florida

Conditions: Adolescent Substance Use
Interventions: Guiding Good Choices; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 11 Years to 12 Years
Enrollment: 3,636 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2025
U.S. locations: 3
States / cities: Oakland, California • Aurora, Colorado • Detroit, Michigan

Conditions: Parkinson Disease, Idiopathic Parkinson Disease
Interventions: Intravenous and Oral n-acetyl cysteine, Control group, Oral Supplements: Baicalin, Ganoderma, Omega 3 and Curcumin; Dietary Supplement · Other
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 30 Years to 80 Years
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2022
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Suicide
Interventions: Crisis Response Planning, Crisis Risk Counseling; Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 191 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Post-intensive Care Syndrome, Transitional Care, Critical Care, Health Services
Interventions: PICTURE-THIS, Enhanced Usual Care, Run-In Phase; Other · Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 50 Years and older
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Opioid Dependence
Interventions: Medsignals, smartphone app; Device
Lead sponsor: Care Team Solutions; Industry
Eligibility: 21 Years and older
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Depression
Interventions: Enhanced BHL Program Services, Standard BHL Program Services; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 65 Years and older
Enrollment: 2,432 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Fatigue
Interventions: Mindfulness-Based Stress Reduction, Attention Control; Behavioral
Lead sponsor: Indiana University; Other
Eligibility: 18 Years and older
Enrollment: 107 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 4
States / cities: Carmel, Indiana • Indianapolis, Indiana

Search by objective public record fields.

Young Adult Tobacco/Nicotine and Cannabis Co-use

A Randomized, Double-blind Placebo-Controlled Pharmacogenetic Study of Topiramate in European-American Heavy Drinkers

Improving Medication Adherence in Hypertensive Patients

A Patient-Spouse Intervention for Self-Managing High Cholesterol

Comparing Non-Medicine Strategies for Improving Low Back Pain

Personalized Exercise Program for Survivors of Breast Cancer, STEPS-BC Trial

POMEGRANATE Trial: Comparing Reia Pessary Versus Standard of Care Pessary for Pelvic Organ Prolapse Treatment

Comprehensive Patient-Centered Home-based Care Coaching for COPD Self-management

SAFETY-Parent: Online Learning Module to Support Parents of Suicidal Youth

eSTEP: An Integrated mHealth Intervention to Engage High-risk Individuals Along the Full PrEP Care Continuum

Pralatrexate With Bendamustine and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory T-Cell Non-Hodgkin Lymphoma

Enhanced Smoking Cessation Intervention for Smokers Exposed to the World Trade Center (WTC) Disaster

Technology-based Training Tool for PHAT Life

Testing the CrOss Systems Technical Assistance for Retaining Staff (COSTARS) Model for Improving Staff Retention Among Child Welfare Workers and Peer Supporters, and Implementation of Evidence Based Interventions.

Peer Engagement in Methamphetamine Harm-Reduction With Contingency Management (PEER-CM)

Social Media Use in Adolescent Diabetes Care

RESCUE Stroke Caregiver Website to Enhance Discharge Planning

Guiding Good Choices for Health

Physiological Effects of Nutritional Support in Patients With Parkinson's Disease

Neural Mechanisms and Predictors of an Ultra-Brief Suicide Prevention Strategy

Pilot Testing PICTURE-THIS

Using mHealth to Aid Opioid Medication Adherence Pilot Study

The PACE/PACENET Behavioral Health Laboratory Project

Treatment for Persistently Fatigued Cancer Survivors: A Randomized Controlled Trial With Biomarker Response