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Conditions: Dislocation, Hip
Interventions: Dual Mobility Implant, Conventional, single-bearing implant; Device
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 322 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2036
U.S. locations: 2
States / cities: New York, New York • Philadelphia, Pennsylvania

Conditions: Non-Pharmacological Pain Management
Interventions: Non-pharmacological Options in post-operative Hospital and Rehabilitative Management (NOHARM); Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 128 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 6
States / cities: Scottsdale, Arizona • Jacksonville, Florida • Mankato, Minnesota + 3 more

Conditions: Degeneration of Lumbar Intervertebral Disc
Interventions: Aspen Spinous Process Fixation Device, Pedicle Screws; Device
Lead sponsor: Zimmer Biomet; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 3
States / cities: Paducah, Kentucky • Lockport, New York • Medford, Oregon

Conditions: End-stage Ankle Arthritis (ESAA), Osteoarthritis (OA)
Interventions: Ankle Arthrodesis, Ankle Arthroplasty; Procedure
Lead sponsor: Seattle Institute for Biomedical and Clinical Research; Other
Eligibility: 21 Years to 89 Years
Enrollment: 517 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2026
U.S. locations: 6
States / cities: Fort Collins, Colorado • Grand Rapids, Michigan • Edina, Minnesota + 2 more

Conditions: Burns, Contracture Scar, Surgical Injury
Interventions: Full Thickness Skin Graft (FTSG), Base of wound fat graft with Split Thickness Skin Graft (STSG) Reconstruction (Autologous Layered Composite Grafting).; Procedure
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 2
States / cities: Pittsburgh, Pennsylvania

Conditions: Mandibular Reconstruction, Segmental Mandibular Defects
Interventions: Surgical Resection and Reconstruction; Procedure
Lead sponsor: AO Innovation Translation Center; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Timeline: 2022 – 2030
U.S. locations: 5
States / cities: Jacksonville, Florida • Chicago, Illinois • New Hyde Park, New York + 2 more

Conditions: Appendicitis
Interventions: Cefoxitin, Ertapenem, Moxifloxacin, Tigecycline, Ticarcillin-Clavulanic Acid; Metronidazole plus Cefazolin, Cefuroxime, Ceftriaxone, Cefotaxime, Ciprofloxacin, or Levofloxacin, Appendectomy; Drug · Procedure
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 1,552 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2021
U.S. locations: 25
States / cities: Sylmar, California • Torrance, California • Aurora, Colorado + 14 more

Conditions: Ventral Hernia
Interventions: Strattice Arm, Bio-A Arm; Device
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 1
States / cities: Charlotte, North Carolina

Conditions: Inguinal Hernia
Interventions: Open Inguinal Hernia Repair, Laparoscopic Inguinal Hernia Repair, Robotic-Assisted Inguinal Hernia Repair; Procedure · Device
Lead sponsor: Intuitive Surgical; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 156 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Single Level Spinal Fusion, Discetomy, Laminectomy
Interventions: Mindfulness training, Acupuncture, Enhanced education; Behavioral · Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Coronary Artery Disease, Angina Pectoris, Cardiac Valve Disease
Interventions: SternaLock Blue closure system, Suture Wire; Device
Lead sponsor: Zimmer Biomet; Industry
Eligibility: 18 Years and older
Enrollment: 236 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 12
States / cities: Jacksonville, Florida • Orlando, Florida • Atlanta, Georgia + 8 more

Conditions: Chronic Subdural Hematoma, Hemorrhage Brain
Interventions: Matched pair Aristotle 14 guidewire and Plato 17 microcatheter, Surgeon combination preference; Device
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Postoperative Pain, Inguinal Hernia
Interventions: Opioids, No opioids; Drug · Other
Lead sponsor: Clayton Petro; Other
Eligibility: 18 Years and older
Enrollment: 904 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 7
States / cities: Fountain Valley, California • Royal Oak, Michigan • Cleveland, Ohio + 3 more

Conditions: Obstructive Sleep Apnea of Child
Interventions: Adenotonsillectomy, Drug-induced sleep endoscopy directed surgery; Procedure
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 2 Years to 18 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Lumbar Disc Disease
Interventions: Autologous bone marrow aspirate injected intradiscal after microdiscectomy, Discectomy only; Procedure
Lead sponsor: New York Presbyterian Hospital; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Hernia Incisional, Suture, Complication
Interventions: Duramesh Laparotomy Closure, Conventional suture closure; Device
Lead sponsor: Uniformed Services University of the Health Sciences; Federal
Eligibility: 18 Years to 75 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 2
States / cities: Baltimore, Maryland • Bethesda, Maryland

Conditions: Hysterectomy
Interventions: Not listed
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older · Female only
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 3
States / cities: Boston, Massachusetts

Conditions: Osteoarthritis, Knee
Interventions: Shared Decision-Making Tool, Video, Standard of Care; Other
Lead sponsor: Yale University; Other
Eligibility: 45 Years to 65 Years
Enrollment: 105 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023
U.S. locations: 3
States / cities: Guilford, Connecticut • Milford, Connecticut • New Haven, Connecticut

Conditions: Abnormal Uterine Bleeding, Uterine Bleeding, Fibroid Uterus, Surgery
Interventions: Total Laparoscopic Hysterectomy; Procedure
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 46 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Carcinoma, Squamous Cell, Head and Neck Neoplasms, Oropharyngeal Neoplasms
Interventions: Intensity Modulated Radiotherapy (IMRT), Cisplatin (or alternative), Assessment for surgical evaluation; Radiation · Drug · Procedure
Lead sponsor: UNC Lineberger Comprehensive Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 115 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2024
U.S. locations: 5
States / cities: Gainesville, Florida • Chapel Hill, North Carolina • Hendersonville, North Carolina + 2 more

Conditions: Prostate Cancer, Quality of Life
Interventions: Retzius sparing; Procedure
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 40 Years to 80 Years · Male only
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: New York, New York

Conditions: Breast Cancer
Interventions: Usual care American Society of Plastic Surgeons booklet "Breast Reconstruction", Decision tool, Usual Care Group - Outcome Measures, Decision Group - Outcome Measures, Demographic and Background Questions; Other
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older · Female only
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Malignant Glioma of Brain
Interventions: 5ALA exoscopic fluorescence filter; Diagnostic Test
Lead sponsor: Northwell Health; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: New York, New York

Conditions: Deep Vein Thrombosis of Lower Limb, Pulmonary Embolism (PE), Bleeding
Interventions: ActiveCare CECT device, Enoxaparin; Device · Drug
Lead sponsor: Medical Compression Systems; Industry
Eligibility: 18 Years and older
Enrollment: 411 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 9
States / cities: La Jolla, California • Loma Linda, California • Los Angeles, California + 6 more

Search by objective public record fields.

Dual Mobility Acetabular Cups in Revision TJA

Pain Management Intervention Preparatory to a Future Pragmatic Trial

Comparison of the Aspen Device Versus Pedicle Screws for Supplemental Posterior Fixation in Lumbar Interbody Fusion

Comparing Ankle Fusion to Ankle Replacement

Autologous Point-of-Care Adipose Therapy: Delayed Injury/Scar

Registry to Collect Data on Patients Undergoing Segmental Mandibular Defect Reconstruction Following Oral Squamous Cell Carcinoma Resection and Drugs-induced Osteonecrosis

The Comparison of Outcomes of Antibiotic Drugs and Appendectomy (CODA) Trial

The Use of Biologic Mesh vs Bioabsorbable Mesh During Ventral Hernia Repair in At-risk Patients

Pain and Quality of Life After Inguinal Hernia Repair

Integration of Mindfulness and Acupuncture After Spine Surgery

An Evaluation of Rigid Sternal Fixation in Supporting Bone Healing and Improving Postoperative Recovery

Microfabricated Microcatheter Advantages in Middle Meningeal Artery Embolization: an Early Experience at a Single Center

No Opioids vs. Minimal Opioids Following Inguinal Hernia Repair

Surgical Treatment of Children With OSA and Small Tonsils or Down Syndrome

Injection of Autologous Bone Marrow Aspirate in Patients With Degenerative Disc Disease.

DuraMesh Laparotomy Closure Following Trauma and Emergency Surgery

Perioperative Outcomes of Common Methods of Minimally Invasive Contained Tissue Extraction

Investigating the Impact of a Shared Decision-Making Tool

Outcomes on Abdominal Versus Vaginal Morcellation At Time of Hysterectomy

De-intensification of Radiation and Chemotherapy for Low-Risk HPV-related Oropharyngeal SCC: Follow-up Study

A Prospective Trial on Nerve Sparing Techniques Performed in Radical Prostatectomy

Optimizing Decision Making About Breast Reconstruction After Mastectomy: A Patient-Centered Approach

Pilot Study Evaluating the Optimization of the ORBEYE Blue Light Filter During Fluorescence-Guided Resection of Gliomas

Deep Vein Thrombosis (DVT) Prevention in Total Hip Arthroplasty: Continuous Enhanced Circulation Therapy (CECT) Versus Low Molecular Weight Heparin (LMWH)