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ClinicalTrials.gov public records Last synced Nov 14, 2026, 6:54 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 529–550 of 550 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Surgical Approach Clear all

Conditions: Intracerebral Hemorrhage
Interventions: Not listed
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 2,500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2033
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Intervertebral Disc Degeneration
Interventions: C5-C6 arthrodesis; Procedure
Lead sponsor: University of Pittsburgh; Other
Eligibility: 21 Years to 60 Years
Enrollment: 106 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2024
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Laparoscopic Colorectal Resection
Interventions: TAP block, Epidural, Paravertebral block, Acetaminophen 1g IV, Dexamethasone 4mg, Midazolam up to 2mg, Propofol 1-2.5 mg/kg, Sevoflurane to keep a bispectral index of between 40-60, Local infiltration with 10 mL of plain ropivacaine 0.25%, Lidocaine, Epinephrine, Hydromorphone; Procedure · Drug
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Stage I - II Primary Lung Cancer, Stage I Lung Cancer, Stage II Lung Cancer, Lung Cancer Stage I, Lung Cancer Stage II, Lung Cancer
Interventions: AveCure 16 Gauge Flexible Microwave Ablation Probe; Device
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 22 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Alcoholic Liver Disease, Non-Alcoholic Fatty Liver Disease, Steatohepatitis, Nonalcoholic, Steatohepatitis
Interventions: Not listed
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 75 Years
Enrollment: 155 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Atrial Fibrillation (AF)
Interventions: Not listed
Lead sponsor: McMaster University; Other
Eligibility: 18 Years to 100 Years
Enrollment: 1,780 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 4
States / cities: Evanston, Illinois • Detroit, Michigan • Great Neck, New York + 1 more

Conditions: Degenerative Disc Disease
Interventions: HEALOS and Leopard Cage, Leopard Cage and Autograft; Device
Lead sponsor: Advanced Technologies and Regenerative Medicine, LLC (ATRM); Other
Eligibility: 18 Years to 70 Years
Enrollment: 138 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2006
U.S. locations: 17
States / cities: Little Rock, Arkansas • Beverly Hills, California • Brandon, Florida + 14 more

Conditions: Breast Cancer, Invasive Breast Cancer
Interventions: Pre-neoadjuvant radiotherapy (NART) biopsy, Neoadjuvant radiotherapy, Unilateral total mastectomy with axillary lymph node dissection; Diagnostic Test · Radiation · Procedure
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 7
States / cities: Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more

Conditions: Colorectal Cancer
Interventions: McCorkle Model Intervention; Other
Lead sponsor: H. Lee Moffitt Cancer Center and Research Institute; Other
Eligibility: 60 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2013
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Breast Cancer Surgery
Interventions: Nipple Sparing Mastectomy (NSM), Skin-Sparing Mastectomy (SSM), Total (Simple) Mastectomy; Procedure
Lead sponsor: Sir Mortimer B. Davis - Jewish General Hospital; Other
Eligibility: 18 Years to 90 Years · Female only
Enrollment: 4,700 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 5
States / cities: New Haven, Connecticut • Boston, Massachusetts • New York, New York + 2 more

Conditions: Benign Polyps of Large Intestine
Interventions: Colonoscopy; Procedure
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 618 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Hip Arthritis, Total Hip Arthroplasty
Interventions: Formal Physical Therapy, Self-directed Physical Therapy; Other
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years to 80 Years
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 2
States / cities: Somerset, New Jersey • Somerville, New Jersey

Conditions: Acute Lower Limb Arterial Occlusion
Interventions: Artix Thrombectomy System; Device
Lead sponsor: Inari Medical; Industry
Eligibility: 18 Years and older
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 26
States / cities: San Francisco, California • New Haven, Connecticut • Washington D.C., District of Columbia + 22 more

Conditions: Radical Cystectomy
Interventions: Surgery Radical Cystectomy, Ultrapro mesh; Procedure
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 178 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2026
U.S. locations: 7
States / cities: Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more

Conditions: Cutaneous Squamous Cell Carcinoma (CSCC)
Interventions: Short course radiation, Active Surveillance; Radiation · Other
Lead sponsor: University of Vermont Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2031
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Knee Osteoarthritis
Interventions: Minimally invasive total knee replacement, Standard approach total knee replacement; Procedure
Lead sponsor: Mayo Clinic; Other
Eligibility: 45 Years to 75 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Malignant Neoplasm of Prostate
Interventions: Da Vinci ® Xi system - MP Robotic Radical Prostatectomy, Da Vinci ® SP system - SP Robotic Radical Prostatectomy; Device
Lead sponsor: Case Comprehensive Cancer Center; Other
Eligibility: 19 Years and older · Male only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Clostridium Difficile Colitis
Interventions: Ileal diversion and lavage, total abdominal colectomy; Procedure
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Gynecologycal Cancer
Interventions: muscle sample, blood draw; Diagnostic Test · Other
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 50 Years and older · Female only
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 2
States / cities: Charlotte, North Carolina • Winston-Salem, North Carolina

Conditions: Total Knee Arthroplasty
Interventions: mini-midvastus surgical approach for total knee arthroplasty, mini-subvastus surgical approach for total knee arthroplasty; Procedure
Lead sponsor: Sinai Hospital of Baltimore; Other
Eligibility: 40 Years and older
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2009
U.S. locations: 1
States / cities: Effingham, Illinois

Conditions: Glaucoma, Open-Angle
Interventions: Xen Gel Stent; Device
Lead sponsor: Johns Hopkins University; Other
Eligibility: Not listed
Enrollment: 137 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Ankle Fractures, Distal Radius Fracture
Interventions: Peripheral Nerve Block; Procedure
Lead sponsor: MaineGeneral Health; Other
Eligibility: 18 Years and older
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Augusta, Maine

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Rapid Evacuation and Access of Cerebral Hemorrhage Registry

Adjacent Segment Mechanics in Cervical Arthrodesis Patients

Comparison Study of Transversus Abdominal Plane, Paravertebral and Epidural Blocks in Laparoscopic Colectomy

Avecure Flexible Microwave Ablation Probe For Lung Nodules

Integrated Approaches for Identifying Molecular Targets in Liver Disease

Perioperative Anticoagulant Use for Surgery Evaluation -Virtual Visit (PAUSE-Virtual)

Safety and Efficacy Study of Healos as a Bone Replacement to Treat Degenerative Disc Disease

A Study of an Alternative Treatment Approach (Preoperative Radiotherapy, Then Mastectomy, Then Immediate Reconstruction Surgery) in People With T4 Breast Cancer

Pilot Study of a Geriatric Intervention After Colorectal and Lung Cancer Surgery

Long-term Safety of Nipple Sparing Mastectomy in Women With High Penetrance Breast Cancer Susceptibility Genes in Breast Cancer

Resect and Discard Approach to Diminutive Colonic Polyps

The Impact of Two Different Physical Therapy Programs in the Rehabilitation of Patients Undergoing Anterior Approach Hip Replacement Surgery

The ArtixASCEND Study

A Study to Determine if Mesh Placement During Bladder Surgery Can Reduce the Chances of Developing a Hernia

MOHs Surgery and Short-Course Radiation Therapy With Structured Follow-Up for Head & Neck Squamous Cell Skin Cancer

Minimally Invasive Surgical Approaches In Total Knee Arthroplasty

Single-Port Versus Multi-Port Robotic Radical Prostatectomy

Optimal Surgical Treatment Of Fulminant Clostridium Difficile Colitis

Role of Mitochondrial Bioenergetics in Resilience for Gynecologic Cancer

A Comparison of Subvastus and Midvastus Approaches in Minimally-Invasive Total Knee Arthroplasty

Retrospective Review of Xen Gel Stent Implantation With Open vs. Closed Conjunctiva Approach

Nerve Block for Pain Control After Fracture Surgery