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Showing 1–24 of 233 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Surgical Gastrojejunostomy Clear all
Terminated No phase listed Observational

Studies of Biological Changes Related to Weight Loss After Gastric Bypass Surgery

NCT00120562
View directory record Official record
Conditions
Obesity, Morbid Obesity, Weight Loss
Interventions
Gastric Bypass Surgery
Procedure
Lead sponsor
Rockefeller University
Other
Eligibility
18 Years to 65 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2007
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 27, 2009 · Synced Sep 22, 2026, 9:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nutritional Effect of an Amino Acid Mixture on Lean Body Mass (LBM) in Post-bariatric Surgery Patients

NCT00473356
View directory record Official record
Conditions
Obesity, Post-gastric Bypass
Interventions
receive amino acid supplement
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 18, 2013 · Synced Sep 22, 2026, 9:45 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Alcohol and Bariatric Surgery

NCT02766322
View directory record Official record
Conditions
Obesity
Interventions
Oral Alcohol challenge test Alcohol visit first, Oral Alcohol challenge test Placebo visit first, Intravenous Alcohol Challenge Test (Clamp), Intravenous Alcohol Self-administration Test
Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
21 Years to 64 Years · Female only
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 10, 2025 · Synced Sep 22, 2026, 9:45 PM EDT
Completed No phase listed Observational

Comparative Effectiveness of Bariatric Surgery Versus Medical Management to Induce Diabetes Remission in Diabetic Patients With BMI 30-35

NCT01423877
View directory record Official record
Conditions
Diabetes
Interventions
Not listed
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 80 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 31, 2014 · Synced Sep 22, 2026, 9:45 PM EDT
Completed No phase listed Observational

Reversal of Obese/Diabetic Cardiomyopathy After Gastric Bypass Surgery

NCT01067209
View directory record Official record
Conditions
Cardiomyopathy
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
35 Years to 70 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 10, 2024 · Synced Sep 22, 2026, 9:45 PM EDT
Completed Phase 4 Interventional Results available

Pilot Study for Zoledronic Acid to Prevent Bone Loss After Bariatric Surgery

NCT03424239
View directory record Official record
Conditions
Bariatric Surgery Candidate
Interventions
Zoledronic Acid, Calcium citrate + vitamin D, Vitamin D3
Drug · Dietary Supplement
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
25 Years to 100 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 28, 2021 · Synced Sep 22, 2026, 9:45 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Trial of Leptin Administration After Roux-en-Y Gastric Bypass

NCT00710814
View directory record Official record
Conditions
Overweight
Interventions
Leptin, Placebo
Drug · Other
Lead sponsor
Columbia University
Other
Eligibility
25 Years to 65 Years · Female only
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 15, 2015 · Synced Sep 22, 2026, 9:45 PM EDT
Completed Not applicable Interventional

DSS: Diabetes Surgery Study - Intensive Medical Management of Type 2 Diabetes, With and Without Gastric Bypass Surgery

NCT00641251
View directory record Official record
Conditions
Type 2 Diabetes, Cardiovascular Disease
Interventions
intensive medical management, RYGB & IMM
Other
Lead sponsor
Medtronic - MITG
Industry
Eligibility
30 Years to 67 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
3
States / cities
Minneapolis, Minnesota • Rochester, Minnesota • New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 28, 2017 · Synced Sep 22, 2026, 9:45 PM EDT
Completed Phase 1 Interventional

Antibiotics, Gastric Bypass, and the Microbiome

NCT05367479
View directory record Official record
Conditions
Obesity, Morbid, Hypertension, Bariatric Surgery Candidate
Interventions
Antibiotic
Drug
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 70 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 9, 2022 · Synced Sep 22, 2026, 9:45 PM EDT
Completed No phase listed Observational

Mechanisms of Diabetes Control After Weight Loss Surgery

NCT00571220
View directory record Official record
Conditions
Gastric Bypass Surgery, Obesity
Interventions
gastric bypass surgery, Diet induced weight loss
Procedure · Other
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
21 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 8, 2018 · Synced Sep 22, 2026, 9:45 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Adipose Secretory Function in Patients Before & After Laparoscopic Surgery

NCT00495599
View directory record Official record
Conditions
Obesity
Interventions
Cytokines assessed from fat tissue
Procedure
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 65 Years
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 20, 2016 · Synced Sep 22, 2026, 9:45 PM EDT
Completed Not applicable Interventional Results available

Reinforcement of Surgical Staple Lines Using Peri-Strips Dry (PSD) With Veritas Collagen Matrix

NCT00566943
View directory record Official record
Conditions
Obesity
Interventions
PSD Veritas Collagen Matrix, Roux-en-Y gastric by-pass surgery with no buttress
Device · Procedure
Lead sponsor
Baxter Healthcare Corporation
Industry
Eligibility
18 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated May 18, 2017 · Synced Sep 22, 2026, 9:45 PM EDT
Terminated Not applicable Interventional

Bariatric Atrial Restoration of Sinus Rhythm

NCT04050969
View directory record Official record
Conditions
Atrial Fibrillation, Morbid Obesity
Interventions
Bariatric surgery, Atrial Fibrillation (AF) Catheter Ablation
Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 70 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Oct 18, 2022 · Synced Sep 22, 2026, 9:45 PM EDT
Terminated No phase listed Observational

A Study to Examine Changes in GIP Plasma Levels Following Gastric Bypass Surgery in Obese Patients

NCT00207389
View directory record Official record
Conditions
Obesity, Type 2 Diabetes Mellitus, Insulin Resistance
Interventions
Not listed
Lead sponsor
Boston Medical Center
Other
Eligibility
21 Years to 64 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 25, 2017 · Synced Sep 22, 2026, 9:45 PM EDT
Terminated Not applicable Interventional

Total Joint Arthroplasty (TJA) Weight Loss Study

NCT05156762
View directory record Official record
Conditions
Osteoarthritis, Hip, Osteoarthritis, Knee, Obesity, Morbid
Interventions
Bariatric surgery, Medical weight loss, Patient research surveys, Total joint arthroplasty (TJA), Usual standard of care
Procedure · Behavioral · Other
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced Sep 22, 2026, 9:45 PM EDT
Completed Phase 1 Interventional

RYGB and the Gastric Adipose Axis

NCT01474785
View directory record Official record
Conditions
Obesity
Interventions
human ghrelin, very low calorie diet, Hyperinsulinemic/Euglycemic Clamp
Drug · Other · Procedure
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 20, 2018 · Synced Sep 22, 2026, 9:45 PM EDT
Completed Not applicable Interventional Results available

The Effect of Pre-Operative Transversus Abdominis Plane (TAP) Block in the Post Operative Opioid Consumption in Morbid Obese Patients Undergoing Laparoscopic Gastric Bypass Surgery: A Prospective,Randomized, Blinded Study

NCT01075087
View directory record Official record
Conditions
Pain, Obesity, Surgery
Interventions
Placebo, (study group) will receive a bilateral TAP block using 20 cc of 0.5% ropivacaine on each side.
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 25, 2014 · Synced Sep 22, 2026, 9:45 PM EDT
Completed Not applicable Interventional

Effect of Bariatric Surgery on Mechanisms of Type 2 Diabetes

NCT01278823
View directory record Official record
Conditions
Obesity, Type 2 Diabetes
Interventions
laparoscopic roux en y gastric bypass operation, medical management
Procedure · Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 60 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 10, 2019 · Synced Sep 22, 2026, 9:45 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Biometabolic Outcomes After Weight Loss Surgery: An Individualized Approach

NCT04841057
View directory record Official record
Conditions
Obesity, Morbid, Metabolic Syndrome, NASH - Nonalcoholic Steatohepatitis
Interventions
50 cm BP limb length, 100 cm BP limb length, 150 cm BP limb length
Procedure
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 80 Years
Enrollment
750 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2031
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Sep 22, 2026, 9:45 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

BAriatric Surgery Induced Chromosomal Change

NCT05903521
View directory record Official record
Conditions
Obesity, Morbid
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Oct 23, 2025 · Synced Sep 22, 2026, 9:45 PM EDT
Terminated No phase listed Observational

Surgical Weight-Loss to Improve Functional Status Trajectories Following Total Knee Arthroplasty (SWIFT Trial)

NCT02598531
View directory record Official record
Conditions
Obesity, Osteoarthritis
Interventions
Not listed
Lead sponsor
Geisinger Clinic
Other
Eligibility
22 Years to 75 Years
Enrollment
289 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2024
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 21, 2025 · Synced Sep 22, 2026, 9:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

fMRI and Appetite-Related Hormones Pre and Post Obesity Surgery

NCT01583725
View directory record Official record
Conditions
Obesity
Interventions
Liquid meal responses, fMRI responses to food-cues
Procedure · Behavioral
Lead sponsor
New York Obesity and Nutrition Research Center
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 26, 2024 · Synced Sep 22, 2026, 9:45 PM EDT
Terminated No phase listed Observational

Long-Term Follow-up of Ohio State University Medical Center (OSUMC) Bariatric Patients

NCT00700843
View directory record Official record
Conditions
Obesity
Interventions
Not listed
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 89 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 14, 2015 · Synced Sep 22, 2026, 9:45 PM EDT
Terminated No phase listed Observational

Obesity and Memory, mRNA, Body Composition, Comorbidity Scale

NCT00531505
View directory record Official record
Conditions
Obesity, Memory Deficits
Interventions
Not listed
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 15, 2015 · Synced Sep 22, 2026, 9:45 PM EDT