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ClinicalTrials.gov public records Last synced Nov 12, 2026, 12:52 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 121–144 of 3,083 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Surgical Management Clear all

Conditions: Coronary Artery Disease, Valvular Heart Disease, Aorta Disease, Heart Failure
Interventions: Sugammadex administration; Drug
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Prostate Cancer
Interventions: Preferred music listening, Relaxation breathing narrative over hypnotic music listening; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 45 Years to 80 Years · Male only
Enrollment: 77 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Obesity
Interventions: bariatric surgery, control; Procedure · Other
Lead sponsor: Neuropsychiatric Research Institute, Fargo, North Dakota; Other
Eligibility: 18 Years to 60 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Fargo, North Dakota

Conditions: Postoperative Pain
Interventions: Extended-Release liposomal bupivacaine (Exparel), Normal saline; Drug
Lead sponsor: Walter Reed National Military Medical Center; Federal
Eligibility: 18 Years and older · Female only
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Bladder Carcinoma, Post-operative Pain
Interventions: Placebo, Questionnaire Administration, Ropivacaine Hydrochloride; Other · Drug
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Pain, Postoperative
Interventions: Fentanyl; Drug
Lead sponsor: Bassett Healthcare; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2014
U.S. locations: 1
States / cities: Cooperstown, New York

Conditions: Surgical Site Infection, Sternal Infection, Cardiac Surgery
Interventions: D-PLEX, Standard of Care; Drug · Other
Lead sponsor: PolyPid Ltd.; Industry
Eligibility: 18 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 2
States / cities: Rochester, Minnesota • Huston, Texas

Conditions: Abdominal Reconstruction
Interventions: Vacuum-assisted closure (VAC) therapy, Gauze dressing; Procedure
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 70 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Pancreas Cancer, Biliary Tract Cancer
Interventions: Alcohol Injection, Placebo Injection; Other
Lead sponsor: Indiana University; Other
Eligibility: 18 Years to 85 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2019
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: NSAID (Non-Steroidal Anti-Inflammatory Drug), Lumbar Spine Fusion, Ketorolac, Postoperative Pain
Interventions: Ketorolac, Naproxen, Standard Postoperative Pain Management; Drug · Other
Lead sponsor: Rothman Institute Orthopaedics; Other
Eligibility: 18 Years and older
Enrollment: 428 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Postoperative Pain Management
Interventions: Not listed
Lead sponsor: Nationwide Children's Hospital; Other
Eligibility: Not listed
Enrollment: 92 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Osteoarthritis, Arthroplasty
Interventions: Ropivacaine with NaCl, Epinephrine, Morphine, Ketorolac Tromethamine, Ropivacaine; Drug
Lead sponsor: Corewell Health East; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Royal Oak, Michigan

Conditions: Head and Neck Cancer, Patients Requiring a Free Flap Surgery
Interventions: FloTrac; Device
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years and older
Enrollment: 94 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Breast Carcinoma In Situ, Breast Ductal Carcinoma In Situ, Breast Lobular Carcinoma In Situ, Stage I Breast Cancer AJCC v7, Stage IA Breast Cancer AJCC v7, Stage IB Breast Cancer AJCC v7, Stage II Breast Cancer AJCC v6 and v7, Stage IIA Breast Cancer AJCC v6 and v7, Stage IIB Breast Cancer AJCC v6 and v7, Stage III Breast Cancer AJCC v7, Stage IIIA Breast Cancer AJCC v7, Stage IIIB Breast Cancer AJCC v7, Stage IIIC Breast Cancer AJCC v7
Interventions: Endoxifen Hydrochloride, Placebo Administration, Questionnaire Administration; Drug · Other
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: 18 Years and older · Female only
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2027
U.S. locations: 3
States / cities: Los Angeles, California • Chicago, Illinois • New York, New York

Conditions: Coronary Artery Disease (CAD)
Interventions: XC001, A195/placebo; Drug
Lead sponsor: XyloCor Therapeutics, Inc.; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 116 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Hand or Wrist Surgery
Interventions: Open Placebo; Drug
Lead sponsor: Brown University; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 2
States / cities: East Providence, Rhode Island • Providence, Rhode Island

Conditions: Postoperative Facial Ecchymosis, Postoperative Facial Edema
Interventions: ELIXIR MD Photobiomodulation (PBM) System; Device
Lead sponsor: Elixir MD Inc; Industry
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Advanced Malignant Neoplasm
Interventions: Cordotomy, Morphine, Questionnaire Administration, Sham Intervention; Procedure · Drug · Other
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2028
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Hemophilia A
Interventions: Recombinant Protein-Free Factor VIII (rAHF-PFM); Drug
Lead sponsor: Baxalta now part of Shire; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 85 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2015
U.S. locations: 10
States / cities: Los Angeles, California • Washington D.C., District of Columbia • Chicago, Illinois + 7 more

Conditions: Juvenile; Scoliosis, Scoliosis Idiopathic, Scoliosis; Adolescence, Scoliosis;Congenital, Kyphosis, Spondylolisthesis
Interventions: CBT (SurgeryPal), Education; Behavioral
Lead sponsor: Seattle Children's Hospital; Other
Eligibility: 12 Years to 18 Years
Enrollment: 433 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Lacerations, Wounds, Injuries
Interventions: Absorbable Suture Arm, Non-absorbable suture (Prolene), suture; Procedure · Device
Lead sponsor: Temple University; Other
Eligibility: 1 Year to 65 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Total Knee Arthroplasty Postoperative Pain, Opioid Reduction After TKA
Interventions: NEUROCUPLE™ Patch, Sham patch, Enhanced Recovery After Surgery (ERAS) Standard of Care; Device · Other
Lead sponsor: Jacques E. Chelly; Other
Eligibility: 18 Years and older
Enrollment: 274 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 3
States / cities: Pittsburgh, Pennsylvania

Conditions: Anesthesia, Upper Extremity Injury
Interventions: Retroclavicular Brachial Plexus Block and Catheter Insertion; Procedure
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years to 100 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Facial Defect
Interventions: cephalexin; Drug
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 236 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2025
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Search by objective public record fields.

Sugammadex Titration in Cardiac Surgery Patients

Music Listening as a Postanesthesia Care Unit (PACU) Nursing Intervention

A Preliminary Comparison of the Blood Levels of Medications in Obese Subjects Compared to Post-Gastric Bypass Subjects

Efficacy of Extended-Release Liposomal Bupivacaine for Post-Operative Urogynecologic Surgery

Continuous Infusion of Ropivacaine Hydrochloride in Reducing Pain After Surgery in Patients With Bladder Cancer

Post-Operative Pain Control in Opioid Tolerant Patients: Fentanyl Challenge Protocol Versus Standard of Care

D-PLEX 302: Efficacy and Safety of D-PLEX in the Prevention of Sternal Infection Post Cardiac Surgery

A Comparison of Incisional Negative-Pressure Wound Therapy Versus Conventional Dressings Following Abdominal Surgery

Surgery Plus Celiac Nerve Block for Long-term Pancreatic Cancer Pain Control

NSAIDS Following Elective Lumbar Spine Fusion

Review of Pain Management After Congenital Cardiac Surgery

Psoas Compartment Block Versus Periarticular Local Anesthetic for Total Hip Arthroplasty

A Prospective Study Evaluating the Use of Intraoperative Stroke Volume Variation Via the FloTrac Device to Guide Fluid and Vasopressor Management in Head and Neck Free Flaps

Phase I Trial of Endoxifen Gel Versus Placebo in Women Undergoing Breast Surgery

Epicardial Delivery of XC001 Gene Therapy to Promote Angiogenesis in CAD Patients Undergoing Treatment With CABG

Using Honest Placebos to Improve Pain Management in Hand Surgery Patients

Perioperative Photobiomodulation in Facial Plastic Surgery

Cordotomy in Reducing Pain in Patients With Advanced Cancer

Phase 3/4 Study of a Recombinant Protein-Free Factor VIII (rAHF-PFM): Comparison of Continuous Infusion Versus Intermittent Bolus Infusion in Hemophilia A Subjects Undergoing Major Orthopedic Surgery

Digital Health Psychosocial Intervention for Adolescent Spine Surgery Preparation and Recovery

Comparison of Cosmetic Outcomes of Lacerations Repaired Using Absorbable Versus Non-absorbable Sutures

NEUROCUPLE™ as an Opioid Alternative Following Total Knee Arthroplasty

Clinical Evaluation of the Ultrasound-Guided Retroclavicular Brachial Plexus Block

The Role of Antibiotics in Full Thickness Skin Graft Survival for Facial Reconstructive Surgery