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ClinicalTrials.gov public records Last synced Oct 21, 2026, 5:45 AM EDT

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Showing 1–24 of 210 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Suture closure Clear all
Terminated Not applicable Interventional Results available

Extended-release Epidural Morphine for Acute Post-operative Analgesia Following Selective Dorsal Rhizotomy in Children

NCT00955877
View directory record Official record
Conditions
Spastic Cerebral Palsy
Interventions
Extended-release Epidural morphine (EREM) 80, Extended-release Epidural Morphine (EREM) 120, Control: Saline
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
2 Years to 12 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 11, 2018 · Synced Oct 21, 2026, 5:45 AM EDT
Not yet recruiting Not applicable Interventional

Cyanoacrylate Skin Adhesive After Mohs Surgery or Wide Local Excision

NCT07844681
View directory record Official record
Conditions
Surgical Site Infection, Skin Cancer, Wound Healing
Interventions
Cyanoacrylate Skin Adhesive, Fast Gut Running Epidermal Suture Closure, Vicryl Rapide Running Epidermal Suture Closure, Prolene Running Epidermal Suture Closure
Device · Procedure
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
3
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 21, 2026, 5:45 AM EDT
Recruiting Not applicable Interventional

Aesthetic Outcome of Intra-dermal Versus Transcutaneous Purse-string Closure

NCT06448481
View directory record Official record
Conditions
Scarring
Interventions
Intra-dermal purse-string closure, Transcutaneous purse-string closure
Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Oct 21, 2026, 5:45 AM EDT
Recruiting Not applicable Interventional

Effect of Collagen Membrane on Ridge Preservation

NCT07580495
View directory record Official record
Conditions
Dehiscence, Tooth Extraction, Alveolar Bone Loss
Interventions
Minimally Invasive tooth extraction, Alveolar ridge preservation with ABCC, Resorbable collagen membrane (InterCollagen® Guide)
Procedure · Device
Lead sponsor
Debora Dias
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Oct 21, 2026, 5:45 AM EDT
Not yet recruiting Not applicable Interventional

Knotless Versus Conventional Sutures for Wound Closure in Cerebral Palsy Multilevel Surgery

NCT07880197
View directory record Official record
Conditions
Cerebral Palsy
Interventions
Knotless barbed suture, Conventional suture
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 21, 2026, 5:45 AM EDT
Completed Not applicable Interventional

Evaluation of Purse-String Closure Vs Second Intention

NCT02062866
View directory record Official record
Conditions
Wound Closure Techniques
Interventions
Purse-String, Second Intent
Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Apr 16, 2015 · Synced Oct 21, 2026, 5:45 AM EDT
Completed Not applicable Interventional Results available

ZIPS Study - Zip Incision aPproximation vs. Suture

NCT02213510
View directory record Official record
Conditions
Wound, Cardiac Arrhythmia
Interventions
Zip Surgical Skin Closure Device, Standard Suture Closure
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated May 30, 2016 · Synced Oct 21, 2026, 5:45 AM EDT
Completed Phase 4 Interventional

Study of Sutures Versus Staples for Skin Closure After Surgical Procedures of Hip

NCT00273715
View directory record Official record
Conditions
Surgery
Interventions
Surgical wound closure techniques, Surgical wound closure techniques (Comparator)
Procedure
Lead sponsor
University of Kentucky
Other
Eligibility
18 Years and older
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 31, 2013 · Synced Oct 21, 2026, 5:45 AM EDT
Completed Not applicable Interventional

Wound Closure Techniques in Primary Spine Surgery

NCT04396613
View directory record Official record
Conditions
Spinal Injuries
Interventions
Closure technique
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 17, 2026 · Synced Oct 21, 2026, 5:45 AM EDT
Recruiting Not applicable Interventional

CLOSM Trial: Groin Closure Using Layered Option for Suture Material

NCT06990425
View directory record Official record
Conditions
Vascular Diseases
Interventions
Groin closure with PDS suture, Groin closure suture material
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
259 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 21, 2026, 5:45 AM EDT
Completed No phase listed Observational

Rhinoplasty Scar Comparison

NCT03748459
View directory record Official record
Conditions
Surgical Incision, Nose Deformity
Interventions
Closure with Permanent Suture, Closure with Resorbable Suture
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 99 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
2
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 4, 2024 · Synced Oct 21, 2026, 5:45 AM EDT
Not listed No phase listed Observational

Characteristics Predictive of Success and Complications in the Use of Suture-Mediated Closure of Femoral Venous Access

NCT00838175
View directory record Official record
Conditions
Cardiac Catheterization
Interventions
suture mediated closure
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 6, 2009 · Synced Oct 21, 2026, 5:45 AM EDT
Completed Phase 2 Interventional Results available

Fibrin Sealant for the Sealing of Dura Sutures

NCT00681824
View directory record Official record
Conditions
Pathological Processes in the Posterior Fossa, Dura Defects
Interventions
Fibrin Sealant, Vapor Heated, Solvent/Detergent-treated with 500 IU/mL thrombin and synthetic aprotinin (FS VH S/D 500 s-apr), Standard of care
Biological · Procedure
Lead sponsor
Baxter Healthcare Corporation
Industry
Eligibility
3 Years and older
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
12
States / cities
Duarte, California • Sacramento, California • San Diego, California + 9 more
Source: ClinicalTrials.gov public record
Updated Jun 27, 2013 · Synced Oct 21, 2026, 5:45 AM EDT
Completed Not applicable Interventional

Sacrocolpopexy With Posterior Repair Obstructed Defecation Symptoms

NCT03658395
View directory record Official record
Conditions
Vaginal Prolapse
Interventions
Laparoscopic Sacrocolopopexy, Posterior repair
Procedure
Lead sponsor
University of Oklahoma
Other
Eligibility
21 Years to 80 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Dec 6, 2024 · Synced Oct 21, 2026, 5:45 AM EDT
Completed Not applicable Interventional

Vaginal Cuff Closure in Robotic Hysterectomy

NCT02696239
View directory record Official record
Conditions
Complications of Medical Care
Interventions
Vaginal cuff closure
Procedure
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 21, 2026, 5:45 AM EDT
Not listed No phase listed Observational

Vascular Closure With Novel External Compression Device: The LockeT Study

NCT06199414
View directory record Official record
Conditions
Atrial Fibrillation, Hemostasis
Interventions
Venous Closure
Device
Lead sponsor
Kansas City Heart Rhythm Research Foundation
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
2
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Jan 10, 2024 · Synced Oct 21, 2026, 5:45 AM EDT
Not listed Not applicable Interventional

Clinical Trial Comparing Tissue Adhesive Vs. Absorbable Suture Vs. Non-Absorbable Suture

NCT00292513
View directory record Official record
Conditions
Cyst of Face, Neck or Shoulder, Pilomatrixoma of Face, Neck or Shoulder
Interventions
standard suture (5-0 prolene), topical skin adhesive (dermabond), absorbable suture (5-0 Chromic gut)
Device
Lead sponsor
Rady Children's Hospital, San Diego
Other
Eligibility
0 Years to 18 Years
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 16, 2006 · Synced Oct 21, 2026, 5:45 AM EDT
Not listed Not applicable Interventional

Primary Fascial Closure With Laparoscopic Ventral Hernia Repair: A Randomized Controlled Trial

NCT02363790
View directory record Official record
Conditions
Hernia, Ventral
Interventions
LVHR PFC, Bridging LVHR
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
189 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
5
States / cities
Washington D.C., District of Columbia • Iowa City, Iowa • Lexington, Kentucky + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 20, 2018 · Synced Oct 21, 2026, 5:45 AM EDT
Completed Not applicable Interventional Results available

Prospective, Multicenter, Multidisciplinary, Controlled Clinical Investigation Evaluating the Safety and Efficacy of PerClot® Polysaccharide Hemostatic System

NCT02359994
View directory record Official record
Conditions
Blood Loss, Surgical
Interventions
PerClot Polysaccharide Hemostatic System, Arista AH
Device
Lead sponsor
Artivion Inc.
Industry
Eligibility
22 Years and older
Enrollment
324 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 17, 2022 · Synced Oct 21, 2026, 5:45 AM EDT
Withdrawn No phase listed Observational

Suture Material for Closure of Hysterotomy

NCT03026647
View directory record Official record
Conditions
Cesarean Section; Complications, Wound, Hematoma
Interventions
Suture
Procedure
Lead sponsor
St. Louis University
Other
Eligibility
14 Years to 55 Years · Female only
Timeline
2017 – 2018
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 13, 2017 · Synced Oct 21, 2026, 5:45 AM EDT
Terminated Not applicable Interventional

Pelvic Floor Support After Laparoscopic Hysterectomy for Benign Conditions: A Randomized Controlled Trial Comparing Vaginal Cuff Closure Techniques

NCT03753516
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Laparoscopic - Vaginal Cuff Closure, Vaginal- Vaginal Cuff Closure
Procedure
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years and older · Female only
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Oct 21, 2026, 5:45 AM EDT
Terminated Not applicable Interventional Results available

Comparison of Cyanoacrylate Tissue Adhesive and Suture for Closure of Cardiac Device Pockets

NCT00674128
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
Cyanoacrylate tissue adhesive (Dermabond), Polyglactin 910 suture (Vicryl)
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years and older
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 29, 2010 · Synced Oct 21, 2026, 5:45 AM EDT
Not listed Not applicable Interventional

Optimal Method of Fascial Closure in High Risk Patients Undergoing Laparotomy

NCT02145052
View directory record Official record
Conditions
Fascial Closure
Interventions
Continuous suture, Interrupted suture
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
388 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 29, 2016 · Synced Oct 21, 2026, 5:45 AM EDT
Completed Phase 4 Interventional Results available

Subcuticular Suture for Cesarean Skin Incision Closure

NCT02459093
View directory record Official record
Conditions
Complications; Cesarean Section, Surgical Wound Infection
Interventions
poliglecaprone 25 suture, polyglactin 910 suture
Device
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
550 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
2
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jun 1, 2018 · Synced Oct 21, 2026, 5:45 AM EDT