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Showing 1–24 of 38 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Swallowing Training Clear all
Terminated Not applicable Interventional

Tongue Pressure Resistance Training for Swallowing Impairment Post-Stroke

NCT03969095
View directory record Official record
Conditions
Stroke, Dysphagia
Interventions
Tongue Pressure Resistance Training
Behavioral
Lead sponsor
University Health Network, Toronto
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Wheaton, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 20, 2022 · Synced Sep 10, 2026, 1:26 AM EDT
Recruiting Phase 2 Interventional

Wearable Biofeedback for Swallowing Disorders Rehabilitation in Stroke and Parkinson Disease

NCT06638944
View directory record Official record
Conditions
Dysphagia, Stroke, Parkinson Disease
Interventions
In-person sEMG-biofeedback, Remote sEMG-biofeedback, Standard-of-care treatment
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
50 Years to 90 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
2
States / cities
Champaign, Illinois • West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Sep 10, 2026, 1:26 AM EDT
Enrolling by invitation Not applicable Interventional

High Intensity Dysphagia Rehab for Acute Ischemic Stroke Patients

NCT05970406
View directory record Official record
Conditions
Dysphagia Following Cerebrovascular Accident
Interventions
high intensity dysphagia therapy
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 99 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 11, 2025 · Synced Sep 10, 2026, 1:26 AM EDT
Completed Not applicable Interventional

Training Swallowing Initiation During Expiration

NCT05278039
View directory record Official record
Conditions
Head and Neck Cancer, Dysphagia, Oropharyngeal Dysphagia, Oropharynx Squamous Cell Carcinoma
Interventions
Respiratory-Swallow Phase Training, Swallow Practice
Behavioral · Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Chicago, Illinois • Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Sep 10, 2026, 1:26 AM EDT
Completed Not applicable Interventional

BCAA Supplemental Study

NCT03339232
View directory record Official record
Conditions
Cirrhosis
Interventions
BCAA Supplement, Physical Activity
Dietary Supplement · Other
Lead sponsor
Loyola University
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 23, 2020 · Synced Sep 10, 2026, 1:26 AM EDT
Completed Not applicable Interventional

Acute Intermittent Hypoxia to Improve Airway Protection in Chronic Traumatic Brain Injury

NCT06520358
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Acute Intermittent Hypoxia (AIH), Task specific Airway Protection Training, Sham AIH
Other · Behavioral
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 80 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Sep 10, 2026, 1:26 AM EDT
Recruiting Not applicable Interventional

K01 Impacts of Lingual Endurance Exercise

NCT06072924
View directory record Official record
Conditions
Dysphagia, Dysphagia, Oropharyngeal, Ischemic Stroke, Stroke
Interventions
Isotonic Endurance Exercise, Sham Exercise
Behavioral
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Sep 10, 2026, 1:26 AM EDT
Recruiting Not applicable Interventional

Combined Respiratory Training in Persons With ALS

NCT05913882
View directory record Official record
Conditions
ALS, Respiratory Insufficiency, Dysphagia
Interventions
Respiratory Muscle Strength Training (LVR+EMST)
Device
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 90 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Sep 10, 2026, 1:26 AM EDT
Completed Not applicable Interventional

Lung Volume Recruitment Combined With Expiratory Muscle Strength Training in ALS

NCT03202017
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis
Interventions
Expiratory Muscle Strength Training (EMST), EMST + Lung Volume Recruitment (LVR)
Procedure
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
2
States / cities
Gainesville, Florida • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 22, 2023 · Synced Sep 10, 2026, 1:26 AM EDT
Recruiting Phase 1Phase 2 Interventional

A Phase 1/2 Study of Intravenous Gene Transfer With an AAV9 Vector Expressing Human Beta-galactosidase in Type I and Type II GM1 Gangliosidosis

NCT03952637
View directory record Official record
Conditions
Lysosomal Diseases, Gangliosidosis, GM1
Interventions
AAV9-GLB1, Abdominal ultrasound, Rituximab, Sirolimus, Methylprednisolone, Prednisone, Audiology assessment with ABR, Bone density scan (DEXA), Electrocardiogram (EKG), Echocardiogram, Electroencephalogram (EEG) awake and extended overnight, Laboratory tests, Lumbar puncture, Brain MRI/MRS/fMRI, Neurocognitive testing, Neurology exam, PICC or other Central line placement, Skeletal survey, Skin biopsy, Speech and modified barium swallow study, Ophthalmology exam
Biological · Procedure · Drug + 3 more
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
6 Months to 12 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Sep 10, 2026, 1:26 AM EDT
Terminated Not applicable Interventional

EMST and Swallowing in Long-Term Survivors of HNCA

NCT03975465
View directory record Official record
Conditions
Head and Neck Neoplasms, Deglutition Disorders
Interventions
Expiratory Muscle Strength Training, Pharyngeal Muscle Strengthening Exercises
Behavioral
Lead sponsor
University of Wisconsin, Milwaukee
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
2
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced Sep 10, 2026, 1:26 AM EDT
Not yet recruiting Not applicable Interventional

Optimizing Dysphagia Treatment Delivery in Acute Care: A Hybrid Efficacy Implementation Trial

NCT07736105
View directory record Official record
Conditions
Dysphagia, Critical Illness
Interventions
Expiratory muscle strength training (EMST), Standard of Care Dysphagia Treatment, Intensive Dysphagia Treatment
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Sep 10, 2026, 1:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Influence of Lifestyle Factors on Neutrophil Migration Pilot Study

NCT02411318
View directory record Official record
Conditions
Neutrophil Chemotactic Response
Interventions
Exercise, ProLab 200mg caffeine capsule, Ethanol ingestion, Glucose Tolerance Drink
Behavioral · Drug · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
21 Years to 60 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 16, 2020 · Synced Sep 10, 2026, 1:26 AM EDT
Recruiting Not applicable Interventional

Tongue Proactive Strengthening Exercise Program Following Partial/Hemi Glossectomy and Reconstruction

NCT07110142
View directory record Official record
Conditions
Oral Cancer, Head and Neck Cancer
Interventions
Tongueometer
Other
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Sep 10, 2026, 1:26 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Motor Learning in Dysphagia Rehabilitation

NCT02576470
View directory record Official record
Conditions
Dysphagia, Swallowing Disorders, Deglutition Disorders, Stroke
Interventions
Biofeedback, Transcranial Direct Current Stimulation, Financial Reward, targeted dysphagia training maneuver, Videofluoroscopy (VF) and Barium, Transcranial Magnetic Stimulation, Submental Electromyography
Behavioral · Device · Radiation
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 100 Years
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 3, 2019 · Synced Sep 10, 2026, 1:26 AM EDT
Completed Not applicable Interventional Results available

Effects of Oropharyngeal Strengthening on Dysphagia in Patients Post-stroke

NCT02322411
View directory record Official record
Conditions
Stroke
Interventions
Isometric Progressive Resistance Oropharyngeal Therapy, Compensatory approaches
Device · Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
21 Years to 95 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 14, 2020 · Synced Sep 10, 2026, 1:26 AM EDT
Completed Not applicable Interventional

Correlation Between Montreal Cognitive Assessment and Voice Therapy Outcomes in the Aging Treatment- Seeking Population

NCT05187910
View directory record Official record
Conditions
Cognitive Impairment, Voice Disorders, Voicebox Disorders, Cognitive Decline, Swallowing Disorder
Interventions
Speech Therapy, Swallowing Therapy, Upper Airway Therapy
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
60 Years to 110 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
4
States / cities
San Francisco, California • Atlanta, Georgia • New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 25, 2023 · Synced Sep 10, 2026, 1:26 AM EDT
Enrolling by invitation Not applicable Interventional

Myofunctional Therapy for Obstructive Sleep Apnea

NCT07301125
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Myofunctional Therapy
Procedure
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 10, 2026, 1:26 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Swallowing in OSA & CPAP Intolerance

NCT06786117
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Healthy
Interventions
SLP swallowing exercises, myofunctional exercises
Other
Lead sponsor
Denise Dewald
Other
Eligibility
40 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 10, 2025 · Synced Sep 10, 2026, 1:26 AM EDT
Not listed Phase 1 Interventional

i-BiSSkApp for Swallowing Rehabilitation in Parkinson's Disease

NCT05837520
View directory record Official record
Conditions
Parkinson Disease
Interventions
i-BiSSkApp (tablet application) with swallowing therapy, Traditional behavioral swallowing therapy
Device · Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 99 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Apr 30, 2023 · Synced Sep 10, 2026, 1:26 AM EDT
Recruiting Not applicable Interventional

Respiratory Strength Training in Heart Transplant Recipients

NCT06190171
View directory record Official record
Conditions
Dysphagia, Heart Transplant Recipients
Interventions
Active respiratory muscle strength training, Sham respiratory muscle strength training
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 90 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Sep 10, 2026, 1:26 AM EDT
Completed Phase 2 Interventional

Volitional Swallowing in Stroke Patients With Chronic Dysphagia

NCT00306501
View directory record Official record
Conditions
Stroke, Dysphagia
Interventions
Swallowing Training
Procedure
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 75 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 10, 2026, 1:26 AM EDT
Completed No phase listed Observational Results available

Use of the Passy Muir Swallowing Self Trainer

NCT02848664
View directory record Official record
Conditions
Stroke, Brain Injury, Head and Neck Cancer
Interventions
Dysphagia retraining with device
Device
Lead sponsor
James Madison University
Other
Eligibility
13 Years to 100 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Harrisonburg, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 10, 2019 · Synced Sep 10, 2026, 1:26 AM EDT
Completed Not applicable Interventional Results available

Clinical Impact of Respiratory-Swallow Training on Refractory Dysphagia in Oropharyngeal Head and Neck Cancer

NCT03377270
View directory record Official record
Conditions
Head and Neck Cancer, Dysphagia
Interventions
Respiratory Swallow Training
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
2
States / cities
Chicago, Illinois • Hines, Illinois
Source: ClinicalTrials.gov public record
Updated May 5, 2025 · Synced Sep 10, 2026, 1:26 AM EDT