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Showing 1–24 of 28 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Synthetic Mesh Clear all
Completed Phase 4 Interventional Results available

Efficacy Study of Vaginal Mesh for Anterior Prolapse

NCT00557882
View directory record Official record
Conditions
Vaginal Prolapse, Uterine Prolapse, Cystocele, Pelvic Organ Prolapse
Interventions
synthetic polypropylene mesh
Device
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
21 Years and older · Female only
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 29, 2020 · Synced Sep 10, 2026, 2:07 AM EDT
Completed No phase listed Observational Results available

Restorelle Direct Fix Anterior and Posterior (A&P) for Female Pelvic Organ Prolapse: A Prospective Post Market Study

NCT01378065
View directory record Official record
Conditions
Pelvic Organ Prolapse (POP)
Interventions
Restorelle Direct Fix A&P
Device
Lead sponsor
Coloplast A/S
Industry
Eligibility
18 Years and older · Female only
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
6
States / cities
Baltimore, Maryland • Grand Rapids, Michigan • Marshall, Missouri + 3 more
Source: ClinicalTrials.gov public record
Updated May 11, 2020 · Synced Sep 10, 2026, 2:07 AM EDT
Not listed Not applicable Interventional

Breast Mesh Used in Two-staged Breast Reconstruction

NCT04967976
View directory record Official record
Conditions
Breast Cancer, Radiation, Breast Reconstruction, Synthetic Mesh
Interventions
TiLoop Bra mesh in expander-implant breast reconstrution, sub-pectoral expander-implant breast reconstruction
Procedure
Lead sponsor
Tianjin Medical University Cancer Institute and Hospital
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 19, 2021 · Synced Sep 10, 2026, 2:07 AM EDT
Completed No phase listed Observational

Uterosacral Ligament Suspension vs Robotic Sacrocolpopexy

NCT02741830
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Not listed
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 9, 2019 · Synced Sep 10, 2026, 2:07 AM EDT
Not listed No phase listed Observational Results available

Review of Complex Recurrent Hernia Repair

NCT01644695
View directory record Official record
Conditions
Recurrent Hernia
Interventions
Bony Anchoring Reinforcement System
Procedure
Lead sponsor
Institute For Advanced Reconstruction
Other
Eligibility
18 Years to 65 Years
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2020
U.S. locations
1
States / cities
Shrewsbury, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 14, 2012 · Synced Sep 10, 2026, 2:07 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

TOMUS-Trial Of Mid-Urethral Slings

NCT00325039
View directory record Official record
Conditions
Urinary Incontinence
Interventions
retropubic mid-urethral sling (TVT), transobturator mid-urethral sling (TVT-O and the Monarc)
Procedure
Lead sponsor
Carelon Research
Other
Eligibility
21 Years and older · Female only
Enrollment
597 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2013
U.S. locations
11
States / cities
Birmingham, Alabama • San Diego, California • Maywood, Illinois + 7 more
Source: ClinicalTrials.gov public record
Updated Jan 13, 2014 · Synced Sep 10, 2026, 2:07 AM EDT
Active, not recruiting Not applicable Interventional Results available

Apical Suspension Repair for Vault Prolapse In a Three-Arm Randomized Trial Design

NCT02676973
View directory record Official record
Conditions
Visceral Prolapse
Interventions
Open, Robotic, or Laparoscopic, Transvaginal Native Tissue Repair, Uphold™ LITE
Procedure
Lead sponsor
NICHD Pelvic Floor Disorders Network
Network
Eligibility
21 Years and older · Female only
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
10
States / cities
Birmingham, Alabama • San Diego, California • Albuquerque, New Mexico + 6 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2025 · Synced Sep 10, 2026, 2:07 AM EDT
Completed No phase listed Observational Results available

Observational Data Collection of Surgical Outcomes in the Treatment of Vaginal Prolapse With AMS Products

NCT00388947
View directory record Official record
Conditions
Vaginal Prolapse
Interventions
AMS Prolapse Product
Device
Lead sponsor
ASTORA Women's Health
Industry
Eligibility
21 Years and older · Female only
Enrollment
1,543 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Whitinsville, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 10, 2016 · Synced Sep 10, 2026, 2:07 AM EDT
Completed Not applicable Interventional Results available

Non-Endoscopic Surveillance for Barrett's Esophagus Following Ablative Therapy

NCT02106910
View directory record Official record
Conditions
Barrett's Esophagus
Interventions
Cytosponge
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 80 Years
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 19, 2020 · Synced Sep 10, 2026, 2:07 AM EDT
Completed Not applicable Interventional Results available

Efficacy Study of Vaginal Mesh for Prolapse

NCT00475540
View directory record Official record
Conditions
Pelvic Organ Prolapse, Uterine Prolapse, Vaginal Prolapse, Cystocele, Rectocele
Interventions
synthetic monofilament polypropylene mesh
Device
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
21 Years and older · Female only
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 11, 2022 · Synced Sep 10, 2026, 2:07 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Biologic Versus Synthetic Mesh for Treatment of Paraesophageal Hernia

NCT02242526
View directory record Official record
Conditions
Hiatal Hernia
Interventions
Parietex™ Composite Hiatal Mesh, North Haven, CT, Biodesign™ Surgisis® Graft, Cook Medical, Bloomington
Device
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years to 80 Years
Enrollment
312 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2020
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Oct 14, 2018 · Synced Sep 10, 2026, 2:07 AM EDT
Terminated Not applicable Interventional Results available

Complex Ventral Hernia Repair Using Biologic or Synthetic Mesh

NCT02041494
View directory record Official record
Conditions
Hernia, Ventral
Interventions
Ventralight, Strattice
Device
Lead sponsor
Hobart Harris
Other
Eligibility
21 Years and older
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 13, 2021 · Synced Sep 10, 2026, 2:07 AM EDT
Not listed No phase listed Observational

Study of Paraesophageal Hernia Repair With Small Intestine Submucosa

NCT00786084
View directory record Official record
Conditions
Hiatal Hernia, Paraesophageal Hernia
Interventions
Not listed
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
4
States / cities
St Louis, Missouri • Portland, Oregon • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 30, 2009 · Synced Sep 10, 2026, 2:07 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Silk Scaffold Surgical Incision Dressing

NCT05508945
View directory record Official record
Conditions
Surgical Incision
Interventions
Dermabond Prineo Skin Closure System, silk, 3M Steri-Strip
Device
Lead sponsor
Mehrdad Mark Mofid
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Apr 17, 2024 · Synced Sep 10, 2026, 2:07 AM EDT
Completed No phase listed Observational

Synthetic Mesh Explant Study

NCT01880021
View directory record Official record
Conditions
Herniorrhaphy, Humans, Polypropylene, Polytetrafluoroethylene, Histology, Materials Testing
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 22, 2016 · Synced Sep 10, 2026, 2:07 AM EDT
Recruiting Not applicable Interventional

Gamete Treatment to Correct Fertilization Failure

NCT01944332
View directory record Official record
Conditions
Infertility
Interventions
gamete treatment
Procedure
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
21 Years to 89 Years
Enrollment
1,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Sep 10, 2026, 2:07 AM EDT
Completed Not applicable Interventional

Mesh Type in Ventral Hernia Repair

NCT03091790
View directory record Official record
Conditions
Ventral Hernia
Interventions
Synthetic Mesh, Biologic Mesh
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 21, 2023 · Synced Sep 10, 2026, 2:07 AM EDT
Recruiting Not applicable Interventional

CAMPR-II RWE TRIAL: A Saline-hydrated Allogeneic Dual-layer Amniotic Membrane Product or a Synthetic, Resorbable Polymeric Wound Matrix to a Coarsened Exact Matched Retrospective Control Cohort of Hard to Heal DFUs and VLUs

NCT07701590
View directory record Official record
Conditions
Wound, Foot, Diabetic Foot Ulcer (DFU), Venus Leg Ulcer
Interventions
Microlyte®, IP 1: Membrane Wrap - Hydro
Device
Lead sponsor
Capsicure, LLC
Network
Eligibility
18 Years and older
Enrollment
147 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
7
States / cities
San Diego, California • Coral Gables, Florida • Miami, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Sep 10, 2026, 2:07 AM EDT
Completed Not applicable Interventional Results available

Biologic Mesh Versus Synthetic Mesh in Repair of Ventral Hernias

NCT02451176
View directory record Official record
Conditions
Ventral Hernia
Interventions
Davol Bard Soft Mesh synthetic, LifeCell Strattice Reconstructive Tissue Biologic
Device
Lead sponsor
Michael Rosen
Other
Eligibility
21 Years and older
Enrollment
253 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
4
States / cities
St Louis, Missouri • Cleveland, Ohio • Greenville, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 6, 2022 · Synced Sep 10, 2026, 2:07 AM EDT
Completed Not applicable Interventional Results available

The Altis® Single Incision Sling System for Female Stress Urinary Incontinence Study

NCT01272284
View directory record Official record
Conditions
Stress Urinary Incontinence
Interventions
Altis® Single Incision Sling System (SIS)
Device
Lead sponsor
Coloplast A/S
Industry
Eligibility
18 Years and older · Female only
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
16
States / cities
Murrieta, California • Hialeah, Florida • Alpharetta, Georgia + 12 more
Source: ClinicalTrials.gov public record
Updated Feb 10, 2021 · Synced Sep 10, 2026, 2:07 AM EDT
Completed Not applicable Interventional

Study of Artelon FLEXBAND® for Patients Undergoing Soft Tissue Reconstruction of the Anterior Talofibular Ligament (ATFL) to Treat Lateral Ankle Instability

NCT06638138
View directory record Official record
Conditions
Lateral Ankle Instability
Interventions
Flexband
Device
Lead sponsor
Stryker Trauma and Extremities
Industry
Eligibility
18 Years to 75 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
8
States / cities
Phoenix, Arizona • Gainesville, Florida • Jacksonville, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 10, 2026, 2:07 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Short Term Outcomes of Heavy-weight Versus Medium-weight Synthetic Mesh

NCT06409091
View directory record Official record
Conditions
Hernia, Ventral, Hernia Incisional
Interventions
Medium weight or Heavy weight mesh
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
1,496 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 13, 2024 · Synced Sep 10, 2026, 2:07 AM EDT
Completed No phase listed Observational

Evaluation of the Avaulta Procedure for the Correction of Pelvic Organ Prolapse - Results at 1 Year

NCT00774215
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Not listed
Lead sponsor
Atlantic Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Morristown, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 25, 2010 · Synced Sep 10, 2026, 2:07 AM EDT
Terminated Not applicable Interventional Results available

The Use of Biologic Mesh vs Bioabsorbable Mesh During Ventral Hernia Repair in At-risk Patients

NCT01794338
View directory record Official record
Conditions
Ventral Hernia
Interventions
Strattice Arm, Bio-A Arm
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 14, 2022 · Synced Sep 10, 2026, 2:07 AM EDT