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ClinicalTrials.gov public records Last synced Nov 1, 2026, 1:23 PM EST

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Showing 697–720 of 9,976 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: TARGET Clear all
Suspended Not applicable Interventional

Focused Ultrasound and Exosomes to Treat Depression, Anxiety, and Dementias

NCT04202770
View directory record Official record
Conditions
Refractory Depression, Anxiety Disorders, Neurodegenerative Diseases
Interventions
Exosomes
Other
Lead sponsor
Neurological Associates of West Los Angeles
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Sep 28, 2022 · Synced Nov 1, 2026, 1:23 PM EST
Recruiting Not applicable Interventional

The Effects of Prophylactic Limited Palmar Fasciectomy on Surgical Outcomes and Scarring

NCT03155854
View directory record Official record
Conditions
Dupuytren Contracture
Interventions
Pretendinous cord excision, Division/manipulation of the cord
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Nov 1, 2026, 1:23 PM EST
Completed Phase 1 Interventional

Single Session Spine Stereotactic Radiosurgery in Metastatic Epidural Spinal Cord Compression

NCT01256554
View directory record Official record
Conditions
Metastatic Epidural Spinal Cord Compression
Interventions
Stereotactic Radiosurgery (SSRS), Questionnaires
Procedure · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 25, 2021 · Synced Nov 1, 2026, 1:23 PM EST
Terminated Phase 2 Interventional Results available

Safety and Preliminary Efficacy Study of WST11 (Stakel®)-Mediated VTP Therapy in Subjects With CNV Associated With AMD

NCT01021956
View directory record Official record
Conditions
Macular Degeneration, Choroidal Neovascularization
Interventions
STAKEL
Drug
Lead sponsor
Steba Biotech S.A.
Other
Eligibility
50 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
3
States / cities
Baltimore, Maryland • West Columbia, South Carolina • Harlingen, Texas
Source: ClinicalTrials.gov public record
Updated Sep 17, 2018 · Synced Nov 1, 2026, 1:23 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Closed-loop TIVA Propofol, Sufentanil and Ketamine Guided by BIS Monitor

NCT01942356
View directory record Official record
Conditions
Acute Cholecystitis, Chronic Cholecystitis
Interventions
TIVA - Hypotension, TIVA - Hypertension, TIVA - Bradycardia, TIVA - Tachycardia, INH - Hypotension, INH - Hypertension, INH - Bradycardia, INH - Tachycardia
Procedure
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 27, 2015 · Synced Nov 1, 2026, 1:23 PM EST
Terminated Not applicable Interventional Results available

Pharmacogenetic Prediction of Metoprolol Effectiveness

NCT02293096
View directory record Official record
Conditions
Hypertension
Interventions
metoprolol succinate, Genotyping, CYP2D6 Phenotyping
Drug · Genetic · Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
30 Years to 80 Years
Enrollment
462 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 16, 2021 · Synced Nov 1, 2026, 1:23 PM EST
Recruiting Not applicable Interventional

Personal BP - CAI Study

NCT06492746
View directory record Official record
Conditions
Blood Pressure
Interventions
HemoSphere Advanced Monitoring Platform with Acumen IQ sensor and Tissue Oximetry Monitoring
Device
Lead sponsor
Becton, Dickinson and Company
Industry
Eligibility
45 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Nov 1, 2026, 1:23 PM EST
Completed Not applicable Interventional Results available

Deep Brain Stimulation for Treatment Resistant Depression

NCT00367003
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Deep Brain Stimulation
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years to 70 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2024
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Nov 1, 2026, 1:23 PM EST
Completed No phase listed Observational

Patient Satisfaction Survey of Non-surgical Urinary Incontinence Treatment

NCT04064970
View directory record Official record
Conditions
Urinary Incontinence
Interventions
patient acceptable symptom state (PASS)
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older · Female only
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Oct 6, 2020 · Synced Nov 1, 2026, 1:23 PM EST
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Extended Emergence Strategy on Post-Anesthesia Care Unit Events After Outpatient Orthopedic Surgery

NCT07533370
View directory record Official record
Conditions
Perioperative Care, EEG Power Spectra, Delirium - Postoperative
Interventions
Standard of Care EEG-Guided Emergence, Extended EEG Emergence Trajectory
Procedure
Lead sponsor
Harrison Shong-Wen Chow
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Nov 1, 2026, 1:23 PM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Patient-Clinic-Community Integration to Prevent Obesity Among Rural Preschool Children

NCT04406441
View directory record Official record
Conditions
Pediatric Obesity, Preventive Medicine, Mentoring, Food Supply
Interventions
Patient Reported Outcome Well Child Visit, Patient Reported Outcome Well Child Visit + Food Care
Behavioral
Lead sponsor
Geisinger Clinic
Other
Eligibility
20 Months to 59 Months
Enrollment
2,040 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 5, 2025 · Synced Nov 1, 2026, 1:23 PM EST
Completed Phase 1Phase 2 Interventional

Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation of Patients With Hematological Diseases

NCT00056966
View directory record Official record
Conditions
Hematologic Malignancy
Interventions
ANTI-CD45, CAMPATH-1H, FK506, Fludarabine, Total Body Irradiation, Stem cell infusion
Drug · Radiation · Procedure
Lead sponsor
Baylor College of Medicine
Other
Eligibility
Not listed
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2006
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 29, 2012 · Synced Nov 1, 2026, 1:23 PM EST
Completed Not applicable Interventional Results available

Care Improving Cognition for ADolescents on the Autism Spectrum

NCT04562688
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
CICADAS only, PEERS + CICADAS and then no-contact, PEERS + Active Comparator and then no-contact
Other
Lead sponsor
Posit Science Corporation
Industry
Eligibility
11 Years to 18 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Nov 1, 2026, 1:23 PM EST
Recruiting Not applicable Interventional

Randomized Clinical Trial of iTEST: A Blended Intervention Targeting Introspective Accuracy

NCT07098169
View directory record Official record
Conditions
Schizophrenia Disorders, Schizoaffective Disorder, Psychotic Disorder
Interventions
iTEST, Active Control
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
3
States / cities
San Diego, California • Miami, Florida • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 23, 2026 · Synced Nov 1, 2026, 1:23 PM EST
Completed Not applicable Interventional Results available

Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Septic Shock

NCT01046669
View directory record Official record
Conditions
Septic Shock, Endotoxemia
Interventions
TORAYMYXIN PMX-20R (PMX cartridge), Standard medical care for septic shock
Device · Other
Lead sponsor
Spectral Diagnostics (US) Inc.
Industry
Eligibility
18 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
33
States / cities
Birmingham, Alabama • Tucson, Arizona • Little Rock, Arkansas + 30 more
Source: ClinicalTrials.gov public record
Updated Feb 26, 2019 · Synced Nov 1, 2026, 1:23 PM EST
Not listed Not applicable Interventional Accepts healthy volunteers

Tailored Messages to Increase Eye Examination Behavior

NCT00649766
View directory record Official record
Conditions
Eye Disease, Eye Care
Interventions
tailored newsletter, targeted newsletter
Behavioral
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
65 Years and older
Enrollment
330 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 1, 2008 · Synced Nov 1, 2026, 1:23 PM EST
Completed Phase 1 Interventional

A Study of DT2216 in Relapsed/Refractory Malignancies

NCT04886622
View directory record Official record
Conditions
Solid Tumor, Hematologic Malignancy
Interventions
DT2216
Drug
Lead sponsor
Dialectic Therapeutics, Inc
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
3
States / cities
Chicago, Illinois • Dallas, Texas • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Apr 16, 2025 · Synced Nov 1, 2026, 1:23 PM EST
Active, not recruiting Phase 2 Interventional

53-Week Study Evaluating the Safety and Efficacy of Intra-articular Injections of TPX-100 With Mild to Severe Tibio-Femoral Osteoarthritis of the Knee

NCT06865079
View directory record Official record
Conditions
Osteoarthritis (OA) of the Knee
Interventions
TPX-100 200mg, Once weekly for 4 weeks, PBS
Drug · Other
Lead sponsor
OrthoTrophix, Inc
Industry
Eligibility
50 Years to 80 Years
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
33
States / cities
Scottsdale, Arizona • Tucson, Arizona • Carrolton, California + 26 more
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Nov 1, 2026, 1:23 PM EST
Recruiting Phase 4 Interventional

Effectiveness and Tolerability of Zavegepant for Acute Migraine Treatment Among Those Using CGRP Targeting Preventive Medications

NCT06401642
View directory record Official record
Conditions
Migraine
Interventions
Zavegepant
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Nov 1, 2026, 1:23 PM EST
Completed Phase 4 Interventional Results available

Efficacy and Safety of Sugammadex Dosed According to Actual Body Weight (ABW) or Ideal Body Weight (IBW) in Reversal of Neuromuscular Blockade (NMB) in Morbidly Obese Participants (MK-8616-146)

NCT03346070
View directory record Official record
Conditions
Neuromuscular Blockade
Interventions
Sugammadex 2 mg/kg ABW, Sugammadex 2 mg/kg IBW, Sugammadex 4 mg/kg ABW, Sugammadex 4 mg/kg IBW, Neostigmine + Glycopyrrolate, Rocuronium or Vecuronium
Drug
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Eligibility
18 Years and older
Enrollment
207 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
13
States / cities
Sacramento, California • Miami, Florida • Kansas City, Kansas + 9 more
Source: ClinicalTrials.gov public record
Updated Jan 28, 2021 · Synced Nov 1, 2026, 1:23 PM EST
Completed Phase 3 Interventional Results available

A Study of First-Line Ambrisentan and Tadalafil Combination Therapy in Subjects With Pulmonary Arterial Hypertension (PAH)

NCT01178073
View directory record Official record
Conditions
Hypertension, Pulmonary
Interventions
ambrisentan, tadalafil
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 75 Years
Enrollment
610 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
61
States / cities
Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 50 more
Source: ClinicalTrials.gov public record
Updated Sep 13, 2017 · Synced Nov 1, 2026, 1:23 PM EST
Completed Not applicable Interventional

BOLD MRI as a Surrogate of Improved Muscle Oxygenation Following Endovascular Therapy for the Treatment of CLI

NCT02601430
View directory record Official record
Conditions
Peripheral Arterial Disease, Critical Limb Ischemia
Interventions
BOLD-MRI
Other
Lead sponsor
Zimmer Biomet
Industry
Eligibility
19 Years to 89 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Springfield, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 12, 2017 · Synced Nov 1, 2026, 1:23 PM EST
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Emotional Cognition: Establishing Constructs and Neural-Behavioral Mechanisms in Older Adults With Depression

NCT05966532
View directory record Official record
Conditions
Major Depressive Disorder (MDD), Healthy Adult Volunteer
Interventions
Hot Cognitive Task, Cold cognitive tasks, Structural magnetic resonance imaging (sMRI), Magnetoencephalography imaging (MEG), four self-report forms per the requirement of the NIH Common Data Elements project, Four self-report measures to assess interpersonal functioning, Clinical assessments, ATHF
Behavioral · Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
21 Years to 80 Years
Enrollment
276 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
2
States / cities
Arlington, Texas • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Nov 1, 2026, 1:23 PM EST
Completed Phase 2 Interventional Results available

UAB 0718 - Phase II Trial to Assess Target Oral Therapy as Adjuvant Chemoprevention in High-Risk Head and Neck Cancer

NCT00570232
View directory record Official record
Conditions
Head and Neck Cancer
Interventions
Erlotinib
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
Not listed
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2015
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 21, 2015 · Synced Nov 1, 2026, 1:23 PM EST