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ClinicalTrials.gov public records Last synced Nov 7, 2026, 9:26 AM EST

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Showing 1–24 of 34 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: TCD Ultrasound Clear all

Conditions: Stroke
Interventions: 2-MHz transcranial Doppler ultrasound, 2-MHz transcranial Doppler ultrasound insonation; Device
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2013
U.S. locations: 2
States / cities: Birmingham, Alabama • Houston, Texas

Conditions: Sturge-Weber Syndrome
Interventions: Not listed
Lead sponsor: Hugo W. Moser Research Institute at Kennedy Krieger, Inc.; Other
Eligibility: 6 Months to 21 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Sickle Cell Disease
Interventions: Voxelotor, Placebo; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 2 Years to 14 Years
Enrollment: 236 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 13
States / cities: Washington D.C., District of Columbia • Miami, Florida • Atlanta, Georgia + 5 more

Conditions: Hypoxia, Hypercapnia
Interventions: L-NMMA, Ketorolac, Ascorbic Acid, Intravenous Catheter, Transcranial Doppler Ultrasound; Drug · Procedure
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 45 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Healthy, Aging
Interventions: MRI, TCD; Device
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 20 Years to 64 Years
Enrollment: 46 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Asymptomatic Carotid Stenosis, Symptomatic Carotid Stenosis, TCD, HITS
Interventions: Transcranial Doppler (TCD); Device
Lead sponsor: Ochsner Health System; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013
U.S. locations: 1
States / cities: New Orleans, Louisiana

Conditions: Right to Left Shunt, Patent Foramen Ovale, Atrial Septal Defect
Interventions: Flow Detection System; Device
Lead sponsor: Cardiox Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 141 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 8
States / cities: Phoenix, Arizona • Los Angeles, California • Aurora, Colorado + 5 more

Conditions: Critical Illness, Pediatric Critical Illness, Respiratory Failure, Traumatic Brain Injury, Cardiac Arrest
Interventions: Transcranial Doppler; Device
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 1 Day to 17 Years
Enrollment: 125 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Traumatic Brain Injury
Interventions: Acupuncture, Sham Acupuncture; Device
Lead sponsor: AOMA Graduate School of Integrative Medicine; Other
Eligibility: 18 Years to 50 Years
Enrollment: 22 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Total Knee Replacement
Interventions: Reaming with Synthes RIA (Reamer-Irrigator-Aspirator), Reaming with conventional reamer; Procedure
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Premature Birth, Extremely Low Birth Weight, Infant, Small for Gestational Age, Intracerebral Hemorrhage
Interventions: Diffuse Correlation Spectroscopy (DCS), Amplitude Integrated Electroencephalography (aEEG); Device
Lead sponsor: Maria Angela Franceschini; Other
Eligibility: 0 Hours to 72 Hours
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Mechanical Circulatory Support
Interventions: Not listed
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Sickle Cell Disease
Interventions: Hematopoietic Stem Cell Transplantation, CliniMACS, See intervention description; Procedure · Device · Drug
Lead sponsor: St. Jude Children's Research Hospital; Other
Eligibility: 2 Years to 16 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2009
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Brain Blood Flow, Neurovascular Control
Interventions: MRI, Transcranial Doppler Ultrasound, Sympathetic Nerve Activity; Device · Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 45 Years to 68 Years
Enrollment: 70 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Cognitive/Functional Effects, Recurrent Breast Cancer, Stage IA Breast Cancer, Stage IB Breast Cancer, Stage II Breast Cancer, Stage IIIA Breast Cancer, Stage IIIB Breast Cancer, Stage IIIC Breast Cancer
Interventions: ultrasound imaging, questionnaire administration, assessment of therapy complications, quality-of-life assessment, magnetic resonance imaging; Procedure · Other
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older · Female only
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Healthy, Carotid Artery Diseases
Interventions: Ultrasound imaging, Magnetic Resonance Imaging (MRI), Neurocognitive testing, Transcranial Doppler (TCD), Pulse Wave Doppler; Device · Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 89 Years
Enrollment: 217 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Intracranial Aneurysm, Aneurysm, Intracranial, Giant Intracranial Aneurysm
Interventions: TCD Ultrasound; Device
Lead sponsor: University of Florida; Other
Eligibility: 18 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Atrial Fibrillation
Interventions: non-invasive testing; Procedure
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Cerebral Aneurysm, Stroke, Vasospasm, Cerebral, Subarachnoid Hemorrhage, Aneurysmal, Aneurysmal Subarachnoid Hemorrhage, Cerebral Ischemia
Interventions: Transcranial Doppler; Diagnostic Test
Lead sponsor: Hackensack Meridian Health; Other
Eligibility: 18 Years and older
Enrollment: 3 participants
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Hackensack, New Jersey

Conditions: Insulin Resistance
Interventions: Hypercapnia, Transcranial Doppler, Cycle ergometer, Cognitive Tests; Other · Device
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 12 Years to 18 Years
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Traumatic Brain Injury, Subarachnoid Hemorrhage, Intracerebral Hemorrhage, Liver Failure, Ischemic Stroke
Interventions: Transcranial Doppler; Diagnostic Test
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 162 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2025
U.S. locations: 3
States / cities: Davis, California • San Francisco, California • Atlanta, Georgia

Conditions: Blood Pressure, Cerebrovascular Reactivity
Interventions: Low Sodium Meal (138 mg sodium), High Sodium Meal (1,495 mg sodium); Other
Lead sponsor: University of Delaware; Other
Eligibility: 18 Years to 45 Years
Enrollment: 37 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Newark, Delaware

Conditions: Anterior Cerebral Artery Syndrome, Anterior Cerebral Artery Stroke, Acute Ischemic Stroke, Cardioembolic Stroke, Vasogenic Cerebral Edema
Interventions: Transcranial Doppler (TCD) examination; Other
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Embolic Stroke of Undetermined Source, Transient Ischemic Attack, Right-To-Left Atrial Shunt, Patent Foramen Ovale
Interventions: NeuralBot Investigational System, Transthoracic Echocardiography (TTE); Diagnostic Test
Lead sponsor: NeuraSignal Inc dba NovaSignal; Industry
Eligibility: 18 Years and older
Enrollment: 154 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 7
States / cities: Phoenix, Arizona • Portland, Oregon • Chattanooga, Tennessee + 3 more

Search by objective public record fields.

CLOTBUST Hands-Free: A Phase I/II Pilot Safety Trial

Biomarker Development in Sturge-Weber Syndrome

Study to Evaluate the Effect of GBT440 on TCD in Pediatrics With Sickle Cell Disease

Impact of NOS, COX, and ROS Inhibition on Cerebral Blood Flow Regulation

Brain Blood Flow: Age and Gender

Transcranial Doppler(TCD) Evaluation of High Intensity Transient Signals and Carotid Disease

Right to Left Cardiac Shunt Detection

Brain Blood Flow and Cerebral Autoregulation Monitoring in Critically Ill Children

Translational Research Examining Acupuncture Treatment in Traumatic Brain Injury

Embolic Events Detected During Total Knee Arthroplasty With the Use of RIA (Reamer-Irrigator-Aspirator)

DCS Study in Extremely Premature Newborns

BRAIN-HEART Ultrasound Study Normative Values for Transcranial Doppler Based Cerebral Blood Flow Assessment

Haploidentical Stem Cell Transplant for Patients With Sickle Cell Disease and Prior Stroke or Abnormal Transcranial Ultrasound

Cardiovascular and Neurovascular Regulation in GWI

Vascular and Cognitive Assessments in Patients With Breast Cancer Undergoing Chemotherapy After Surgery

Early Detection of Vascular Dysfunction Using Biomarkers From Lagrangian Carotid Strain Imaging

Transcranial Doppler Ultrasound Monitoring During Flow-Diverter Embolization

The Effect of Atrial Fibrillation Hemodynamics on Regulation of Cerebral Blood Flow

Variability in Transcranial Doppler Technique in Neuro-Critical Care Patients

Exercise in Adolescents With Insulin Resistance

NOninVasive Intracranial prEssure From Transcranial doppLer Ultrasound Development of a Comprehensive Database of Multimodality Monitoring Signals for Brain-Injured Patients

Effects of Acute Dietary Sodium on Cerebrovascular Reactivity and Blood Pressure Reactivity

Transcranial Doppler Evaluation After Endovascular Thrombectomy for Acute Ischemic Stroke (PRECISE-TCD)

RoBotic TCD Ultrasound BubbLe Study Compared to Transthoracic Echocardiography for Detection of Right to Left Shunt